Enhanced evolvability in immunoglobulin V genes under somatic hypermutation

Journal of Molecular Evolution

Volumn 49, Issue 1, 1999, Pages 23-26

  Cowell, Lindsay G ^a   Kim, Hye Jung ^b   Humaljoki, Tiina ^b   Berek, Claudia ^b   Kepler, Thomas B ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

Author keywords

Adaptability; Affinity maturation; Genome evolution; Somatic hypermutation

Indexed keywords

ADAPTATION; ARTICLE; CELL MATURATION; CELL MIGRATION; CHROMOSOME REARRANGEMENT; GENE MUTATION; GENE REARRANGEMENT; GENE TARGETING; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOGLOBULIN VARIABLE REGION; OPEN READING FRAME; SOMATIC MUTATION;

ARTHRITIS; ARTHRITIS, RHEUMATOID; DNA, COMPLEMENTARY; EVOLUTION, MOLECULAR; GENE FREQUENCY; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; MUTATION; SELECTION (GENETICS); SERINE;

DARWINIA;

EID: 0033050612     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00006530     Document Type: Article

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