The intrinsic hypermutability of antibody heavy and light chain genes decays exponentially

EMBO Journal

Volumn 20, Issue 16, 2001, Pages 4570-4576

  Rada, C ^a   Milstein, C ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Decay; Error prone DNA repair; Hypermutation; RNA pol II; Transcription

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; RNA POLYMERASE II;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA REPAIR; MOUSE; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION;

ANIMALS; BINDING SITES; GENES, IMMUNOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; MUTAGENESIS; PROMOTER REGIONS (GENETICS);

ANIMALIA;

EID: 0035881820     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.16.4570     Document Type: Article

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