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Volumn 32, Issue 1, 2007, Pages 1-14

p38 mitogen-activated protein kinase plays a critical role in the control of energy metabolism and development of cardiovascular diseases

Author keywords

Adipocyte; Apoptosis; Diabetes; Gluconeogenesis; Glucose transporter 4 (Glut 4); Glucose uptake; Insulin secretion; Insulin signaling; Obesity; p38; Phosphoenolpyruvate carboxykinase (PEPCK); Skeletal muscle; Uncoupling protein 1 (UCP1)

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 33947579564     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (156)
  • 1
    • 0033965158 scopus 로고    scopus 로고
    • The p38 signal transduction pathway; activation and function[J]
    • Ono K, Han J. The p38 signal transduction pathway; activation and function[J]. Cell Signal, 2000,12(1):1-13.
    • (2000) Cell Signal , vol.12 , Issue.1 , pp. 1-13
    • Ono, K.1    Han, J.2
  • 2
    • 0035920122 scopus 로고    scopus 로고
    • beta-Adrenergic activation of p38 MAP kinase in adipocytes: CAMP induction of the uncoupling protein 1 (UCP1) gene requires p38 MAP kinase[J]
    • Cao W, Medvedev A V, Daniel KW, et al. beta-Adrenergic activation of p38 MAP kinase in adipocytes: cAMP induction of the uncoupling protein 1 (UCP1) gene requires p38 MAP kinase[J]. J Biol Chem, 2001,276(29):27077-27082.
    • (2001) J Biol Chem , vol.276 , Issue.29 , pp. 27077-27082
    • Cao, W.1    Medvedev, A.V.2    Daniel, K.W.3
  • 3
    • 1642293248 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene[J]
    • Cao W, Daniel K W, Robidoux J, et al. p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene[J]. Mol Cell Biol, 2004,24(7):3057-3067.
    • (2004) Mol Cell Biol , vol.24 , Issue.7 , pp. 3057-3067
    • Cao, W.1    Daniel, K.W.2    Robidoux, J.3
  • 4
    • 20744441357 scopus 로고    scopus 로고
    • Selective activation of MAP kinase kinase-3 and p38 MAP kinase is essential for cAMP-dependent UCP1 expression in adipocytes[J]
    • Robidoux J, Cao W, Quan H, et al. Selective activation of MAP kinase kinase-3 and p38 MAP kinase is essential for cAMP-dependent UCP1 expression in adipocytes[J]. Mol Cell Biol, 2005, 25(13):5466-5479.
    • (2005) Mol Cell Biol , vol.25 , Issue.13 , pp. 5466-5479
    • Robidoux, J.1    Cao, W.2    Quan, H.3
  • 5
    • 30044436829 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis [J]
    • Cao W, Collins Q F, Becker T C, et al. p38 mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis [J]. J Biol Chem, 2005,280(52):42731-42737.
    • (2005) J Biol Chem , vol.280 , Issue.52 , pp. 42731-42737
    • Cao, W.1    Collins, Q.F.2    Becker, T.C.3
  • 6
    • 3843142820 scopus 로고    scopus 로고
    • Glucose regulates interleukin-8 production in aortic endothelial cells through activation of the p38 mitogen-activated protein kinase pathway in diabetes [J]
    • Srinivasan S, Bolick D T, Hatley M E, et al. Glucose regulates interleukin-8 production in aortic endothelial cells through activation of the p38 mitogen-activated protein kinase pathway in diabetes [J]. J Biol Chem, 2004,279(30):31930-31936.
    • (2004) J Biol Chem , vol.279 , Issue.30 , pp. 31930-31936
    • Srinivasan, S.1    Bolick, D.T.2    Hatley, M.E.3
  • 7
    • 0034993799 scopus 로고    scopus 로고
    • Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells[J]
    • Nakagami H, Morishita R, Yamamoto K, et al. Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells[J]. Diabetes, 2001,50(6):1472-1481.
    • (2001) Diabetes , vol.50 , Issue.6 , pp. 1472-1481
    • Nakagami, H.1    Morishita, R.2    Yamamoto, K.3
  • 8
    • 33746667829 scopus 로고    scopus 로고
    • Hyperglycemia accelerated endothelial progenitor cell eenescence via the activation of p38 mitogen-activated protein kinase [J]
    • Kuki S, Imanishi T, Kobayashi K, et al. Hyperglycemia accelerated endothelial progenitor cell eenescence via the activation of p38 mitogen-activated protein kinase [J]. Circ J, 2006,70 (8):1076-1081.
    • (2006) Circ J , vol.70 , Issue.8 , pp. 1076-1081
    • Kuki, S.1    Imanishi, T.2    Kobayashi, K.3
  • 9
    • 33749329784 scopus 로고    scopus 로고
    • Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase[J]
    • Wang X L, Zhang L, Youker K, et al. Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase[J]. Diabetes, 2006,55(8):2301-2310.
    • (2006) Diabetes , vol.55 , Issue.8 , pp. 2301-2310
    • Wang, X.L.1    Zhang, L.2    Youker, K.3
  • 10
    • 33748299056 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase mediates free fatty acid-induced gluconeogenesis in hepatocytes[J]
    • Collins Q F, Xiong Y, Lupo J, et al. p38 mitogen-activated protein kinase mediates free fatty acid-induced gluconeogenesis in hepatocytes[J]. J Biol Chem, 2006 281 (34):24336-24344.
    • (2006) J Biol Chem , vol.281 , Issue.34 , pp. 24336-24344
    • Collins, Q.F.1    Xiong, Y.2    Lupo, J.3
  • 11
    • 0036710513 scopus 로고    scopus 로고
    • An adipocentric view of signaling and intracellular trafficking[J]
    • Mora S, Pessin J E. An adipocentric view of signaling and intracellular trafficking[J]. Diabetes Metab Res Rev, 2002,18(5):345-356.
    • (2002) Diabetes Metab Res Rev , vol.18 , Issue.5 , pp. 345-356
    • Mora, S.1    Pessin, J.E.2
  • 12
    • 22844437863 scopus 로고    scopus 로고
    • Endocrine and signalling role of adipose tissue: New perspectives on fat[J]
    • Trayhurn P. Endocrine and signalling role of adipose tissue: new perspectives on fat[J]. Acta Physiol Scand, 2005,184(4):285-293.
    • (2005) Acta Physiol Scand , vol.184 , Issue.4 , pp. 285-293
    • Trayhurn, P.1
  • 13
    • 4444358045 scopus 로고    scopus 로고
    • Leptin and the control of metabolism: Role for stearoyl-CoA desaturase-1 (SCD-1)[J]
    • Cohen P, Friedman J M. Leptin and the control of metabolism: role for stearoyl-CoA desaturase-1 (SCD-1)[J]. J Nutr, 2004,134 (9):2455S-2463S.
    • (2004) J Nutr , vol.134 , Issue.9
    • Cohen, P.1    Friedman, J.M.2
  • 14
    • 0000898480 scopus 로고    scopus 로고
    • Second ed. W. B. Saunders Company, Philadelphia, London, Toronto, Montreal, Sydney, Tokyo
    • Nedergaard J, Cannon B. Brown Adipose Tissue: Development and Function[M]. Second ed. W. B. Saunders Company, Philadelphia, London, Toronto, Montreal, Sydney, Tokyo, 1998:478-489.
    • (1998) Brown Adipose Tissue: Development and Function[M] , pp. 478-489
    • Nedergaard, J.1    Cannon, B.2
  • 16
    • 0031945461 scopus 로고    scopus 로고
    • Cold-induced thermoregulation and biological aging[J]
    • Florez-Duquet M, McDonald R B. Cold-induced thermoregulation and biological aging[J]. Physiol Rev, 1998,78(2):339-358.
    • (1998) Physiol Rev , vol.78 , Issue.2 , pp. 339-358
    • Florez-Duquet, M.1    McDonald, R.B.2
  • 17
    • 0028224485 scopus 로고
    • 3-agonist, on energy balance and brown and white adipose tissues in rats[J]
    • 3-agonist, on energy balance and brown and white adipose tissues in rats[J]. Am J Physiol, 1994,266 (4 Pt 2):R1371-R1382.
    • (1994) Am J Physiol , vol.266 , Issue.4 PART 2
    • Himms-Hagen, J.1    Cui, J.2    Danforlh Jr, E.3
  • 18
    • 0031025546 scopus 로고    scopus 로고
    • Strain-specific response to beta 3-adrenergic receptor agonist treatment of diet-induced obesity in mice[J]
    • Collins S, Daniel K W, Petro A E, et al. Strain-specific response to beta 3-adrenergic receptor agonist treatment of diet-induced obesity in mice[J]. Endocrinology, 1997,138(1):405-413.
    • (1997) Endocrinology , vol.138 , Issue.1 , pp. 405-413
    • Collins, S.1    Daniel, K.W.2    Petro, A.E.3
  • 19
    • 0032043141 scopus 로고    scopus 로고
    • Anti-obesity effects of selective agonists to the β3-adrenergic receptor in dogs[J]. II. Recruitment of thermogenic brown adipocytes and reduction of adiposity after chronic treatment with a β3-adrenergic agonist[J]
    • Sasaki N, Uchida E, Niiyama M, et al. Anti-obesity effects of selective agonists to the β3-adrenergic receptor in dogs[J]. II. Recruitment of thermogenic brown adipocytes and reduction of adiposity after chronic treatment with a β3-adrenergic agonist[J]. J Vet Med Sci, 1998,60(4):465-469.
    • (1998) J Vet Med Sci , vol.60 , Issue.4 , pp. 465-469
    • Sasaki, N.1    Uchida, E.2    Niiyama, M.3
  • 20
    • 0025836657 scopus 로고
    • β3-Adrenergic receptor stimulation restores message and expression of brown-fat mitochondrial uncoupling protein in adult dogs[J]
    • Champigny O, Ricquier D, Blondel O, et al. β3-Adrenergic receptor stimulation restores message and expression of brown-fat mitochondrial uncoupling protein in adult dogs[J]. Proc Natl Acad Sci USA, 1991,88(23):10774-10777.
    • (1991) Proc Natl Acad Sci USA , vol.88 , Issue.23 , pp. 10774-10777
    • Champigny, O.1    Ricquier, D.2    Blondel, O.3
  • 21
    • 0032081279 scopus 로고    scopus 로고
    • A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys[J]
    • Fisher M H, Amend A M, Bach T J, et al. A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys[J]. J Clin Invest, 1998,101(11):2387-2393.
    • (1998) J Clin Invest , vol.101 , Issue.11 , pp. 2387-2393
    • Fisher, M.H.1    Amend, A.M.2    Bach, T.J.3
  • 22
    • 0033610788 scopus 로고    scopus 로고
    • Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis[J]
    • Engelman JA, Lisanti MP, Scherer PE. Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis[J]. J Biol Chem, 1998,273(48):32111-32120.
    • (1998) J Biol Chem , vol.273 , Issue.48 , pp. 32111-32120
    • Engelman, J.A.1    Lisanti, M.P.2    Scherer, P.E.3
  • 23
    • 1242338174 scopus 로고    scopus 로고
    • Co-treatment with dexamethasone and octanoate induces adipogenesis in 3T3-L1 cells[J]
    • Takenouchi T, Takayama Y, Takezawa T. Co-treatment with dexamethasone and octanoate induces adipogenesis in 3T3-L1 cells[J]. Cell Biol Int, 2004,28(3):209-216.
    • (2004) Cell Biol Int , vol.28 , Issue.3 , pp. 209-216
    • Takenouchi, T.1    Takayama, Y.2    Takezawa, T.3
  • 24
    • 0033544862 scopus 로고    scopus 로고
    • Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis[J]
    • Engelman J A, Berg A H, Lewis R Y, et al. Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis[J]. J Biol Chem, 1999, 274(50):35630-35638.
    • (1999) J Biol Chem , vol.274 , Issue.50 , pp. 35630-35638
    • Engelman, J.A.1    Berg, A.H.2    Lewis, R.Y.3
  • 25
    • 0037323398 scopus 로고    scopus 로고
    • Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis[J]
    • Hata K, Nishimura R, Ikeda F, et al. Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis[J]. Mol Biol Cell, 2003,14(2):545-555.
    • (2003) Mol Biol Cell , vol.14 , Issue.2 , pp. 545-555
    • Hata, K.1    Nishimura, R.2    Ikeda, F.3
  • 26
    • 0027465113 scopus 로고
    • Regulation of adipocyte gene expression in diffenentiation and syndromes of obesity/diabetes[J]
    • Spiegelman B M, Choy L, Hotamisligil G S, et al. Regulation of adipocyte gene expression in diffenentiation and syndromes of obesity/diabetes[J]. Journal of Biological Chemistry, 1993,268 (10):6823-6826.
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.10 , pp. 6823-6826
    • Spiegelman, B.M.1    Choy, L.2    Hotamisligil, G.S.3
  • 27
    • 0030297919 scopus 로고    scopus 로고
    • Adipogenesis and obesity; rounding out the big picture[J]
    • Spiegelman B M, Flier J S. Adipogenesis and obesity; rounding out the big picture[J]. Cell, 1996,87(3):377-389.
    • (1996) Cell , vol.87 , Issue.3 , pp. 377-389
    • Spiegelman, B.M.1    Flier, J.S.2
  • 28
    • 33644856152 scopus 로고    scopus 로고
    • The when and wheres of CDC25 phosphatases[J]
    • Boutros R, Doziers C, Ducommum B. The when and wheres of CDC25 phosphatases[J]. Curr Opin Cell Biol, 2006,18(2):185-191.
    • (2006) Curr Opin Cell Biol , vol.18 , Issue.2 , pp. 185-191
    • Boutros, R.1    Doziers, C.2    Ducommum, B.3
  • 29
    • 33644751833 scopus 로고    scopus 로고
    • Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages[J]
    • Aouadi M, Laurent K, Prot M, et al. Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages[J]. Diabetes, 2006,55(2):281-289.
    • (2006) Diabetes , vol.55 , Issue.2 , pp. 281-289
    • Aouadi, M.1    Laurent, K.2    Prot, M.3
  • 30
    • 33947600777 scopus 로고    scopus 로고
    • Xiong Y, Collins Q F, Lupo J G, et al. p38 mitogen-activated protein kinase plays an inhibitory role in hepatic lipogenesis[J]. J Biol Chem, 2006, [Epub ahead of print].
    • Xiong Y, Collins Q F, Lupo J G, et al. p38 mitogen-activated protein kinase plays an inhibitory role in hepatic lipogenesis[J]. J Biol Chem, 2006, [Epub ahead of print].
  • 31
    • 0033537853 scopus 로고    scopus 로고
    • An inhibitor of p38 mitogen-activated protein kinase prevents insulin- stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes[J]
    • Sweeney G, Sornwar R, Ramlal T, et al. An inhibitor of p38 mitogen-activated protein kinase prevents insulin- stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes[J]. J Biol Chem, 1999,274(15):10071-10078.
    • (1999) J Biol Chem , vol.274 , Issue.15 , pp. 10071-10078
    • Sweeney, G.1    Sornwar, R.2    Ramlal, T.3
  • 32
    • 0035920212 scopus 로고    scopus 로고
    • Potentiation of insulin-related signal transduction by a novel protein-tyrosine phosphatase inhibitor, Et-3,4-dephostatin, on cultured 3T3-L1 adipocytes[J]
    • Suzuki T, Hiroki A, Watanabe T, et al. Potentiation of insulin-related signal transduction by a novel protein-tyrosine phosphatase inhibitor, Et-3,4-dephostatin, on cultured 3T3-L1 adipocytes[J]. J Biol Chem, 2001,276(29):27511-27518.
    • (2001) J Biol Chem , vol.276 , Issue.29 , pp. 27511-27518
    • Suzuki, T.1    Hiroki, A.2    Watanabe, T.3
  • 33
    • 0036723740 scopus 로고    scopus 로고
    • Need for GLUT4 activation to reach maximum effect of insulin-mediated glucose uptake in brown adipocytes isolated from GLUT4myc-expressing mice[J]
    • Konrad D, Bilan P J, Nawaz Z, et al. Need for GLUT4 activation to reach maximum effect of insulin-mediated glucose uptake in brown adipocytes isolated from GLUT4myc-expressing mice[J]. Diabetes, 2002,51(9):2719-2726.
    • (2002) Diabetes , vol.51 , Issue.9 , pp. 2719-2726
    • Konrad, D.1    Bilan, P.J.2    Nawaz, Z.3
  • 34
    • 0347721775 scopus 로고    scopus 로고
    • A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation[J]
    • Somwar R, Koterski S, Sweeney G, et al. A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation[J]. J Biol Chem, 2002,277 (52):50386-50395.
    • (2002) J Biol Chem , vol.277 , Issue.52 , pp. 50386-50395
    • Somwar, R.1    Koterski, S.2    Sweeney, G.3
  • 35
    • 15444375497 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase inhibitor SB203580 reduces glucose turnover by the glucose transporter-4 of 3T3-L1 adipocytes in the insulin-stimulated state[J]
    • Bazuine M, Carlotti F, Rabelink M J, et al. The p38 mitogen-activated protein kinase inhibitor SB203580 reduces glucose turnover by the glucose transporter-4 of 3T3-L1 adipocytes in the insulin-stimulated state[J]. Endocrinology, 2005,146(4):1818-1824.
    • (2005) Endocrinology , vol.146 , Issue.4 , pp. 1818-1824
    • Bazuine, M.1    Carlotti, F.2    Rabelink, M.J.3
  • 36
    • 0141815503 scopus 로고    scopus 로고
    • Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity[J]
    • Bazuine M, Ouwens D M, Gomes de Mesquita D S, et al. Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity[J]. Eur J Biochem, 2003,270(19):3891-3903.
    • (2003) Eur J Biochem , vol.270 , Issue.19 , pp. 3891-3903
    • Bazuine, M.1    Ouwens, D.M.2    Gomes de Mesquita, D.S.3
  • 37
    • 0033766405 scopus 로고    scopus 로고
    • Stimulation of MAPK cascades by insulin and osmotic shock: Lack of an involvement of p38 mitogen-activated protein kinase in glucose transport in 3T3-L1 adipocytes[J]
    • Kayali A G, Austin D A, Webster N J. Stimulation of MAPK cascades by insulin and osmotic shock: lack of an involvement of p38 mitogen-activated protein kinase in glucose transport in 3T3-L1 adipocytes[J]. Diabetes, 2000,49(11):1783-1793.
    • (2000) Diabetes , vol.49 , Issue.11 , pp. 1783-1793
    • Kayali, A.G.1    Austin, D.A.2    Webster, N.J.3
  • 38
    • 0035827642 scopus 로고    scopus 로고
    • MKK6/3 and p38 MAPK pathway activation is not necessary for insulin- induced glucose uptake but regulates glucose transporter expression[J]
    • Fujishiro M, Gotoh Y, Katagiri H, et al. MKK6/3 and p38 MAPK pathway activation is not necessary for insulin- induced glucose uptake but regulates glucose transporter expression[J]. J Biol Chem, 2001,276(23):19800-19806.
    • (2001) J Biol Chem , vol.276 , Issue.23 , pp. 19800-19806
    • Fujishiro, M.1    Gotoh, Y.2    Katagiri, H.3
  • 39
    • 20444458773 scopus 로고    scopus 로고
    • Pharmacological inhibition of p38 MAP kinase results in improved glucose uptake in insulin-resistant 3T3-L1 adipocytes[J]
    • Carlson C J, Rondinone C M. Pharmacological inhibition of p38 MAP kinase results in improved glucose uptake in insulin-resistant 3T3-L1 adipocytes[J]. Metabolism, 2005,54(7):895-901.
    • (2005) Metabolism , vol.54 , Issue.7 , pp. 895-901
    • Carlson, C.J.1    Rondinone, C.M.2
  • 40
    • 15444361999 scopus 로고    scopus 로고
    • Endofacial competitive inhibition of glucose transporter-4 intrinsic activity by the mitogen-activated protein kinase inhibitor SB203580[J]
    • Ribe D, Yang J, Patel S, et al. Endofacial competitive inhibition of glucose transporter-4 intrinsic activity by the mitogen-activated protein kinase inhibitor SB203580[J]. Endocrinology, 2005,146 (4):1713-1717.
    • (2005) Endocrinology , vol.146 , Issue.4 , pp. 1713-1717
    • Ribe, D.1    Yang, J.2    Patel, S.3
  • 41
    • 0037341276 scopus 로고    scopus 로고
    • Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: Potential role of p38 in the downregulalion of GLUT4 expression[J]
    • Carlson C J, Koterski S, Sciotti R J, et al. Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulalion of GLUT4 expression[J]. Diabetes, 2003,52(3):634-641.
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 634-641
    • Carlson, C.J.1    Koterski, S.2    Sciotti, R.J.3
  • 42
    • 0035937474 scopus 로고    scopus 로고
    • TNF-alpha inhibits UCP-1 expression in brown adipocytes via ERKs. Opposite effect of p38MAPK[J]
    • Valladares A, Roncero C, Benito M, et al. TNF-alpha inhibits UCP-1 expression in brown adipocytes via ERKs. Opposite effect of p38MAPK[J]. FEBS Lett, 2001,493(1):6-11.
    • (2001) FEBS Lett , vol.493 , Issue.1 , pp. 6-11
    • Valladares, A.1    Roncero, C.2    Benito, M.3
  • 43
    • 0037414826 scopus 로고    scopus 로고
    • Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes[J]
    • Teruel T, Hernandez R, Benito M, et al. Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes[J]. J Biol Chem, 2003,278(1):263-269.
    • (2003) J Biol Chem , vol.278 , Issue.1 , pp. 263-269
    • Teruel, T.1    Hernandez, R.2    Benito, M.3
  • 44
    • 24344476219 scopus 로고    scopus 로고
    • Transcriptional synergy and the regulation of Ucp1 during brown adipocyte induction in white fat depots[J]
    • Xue B, Coulter A, Rim J S, et al. Transcriptional synergy and the regulation of Ucp1 during brown adipocyte induction in white fat depots[J]. Mol Cell Biol, 2005,25(15):8311-8322.
    • (2005) Mol Cell Biol , vol.25 , Issue.15 , pp. 8311-8322
    • Xue, B.1    Coulter, A.2    Rim, J.S.3
  • 45
    • 20144387426 scopus 로고    scopus 로고
    • Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta[J]
    • Kramer D K, Al-Khalili L, Perrini S, et al. Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta[J]. Diabetes, 2005, 54(4):1157-1163.
    • (2005) Diabetes , vol.54 , Issue.4 , pp. 1157-1163
    • Kramer, D.K.1    Al-Khalili, L.2    Perrini, S.3
  • 46
    • 2942733636 scopus 로고    scopus 로고
    • Exercise signalling to glucose transport in skeletal muscle[J]
    • Richter E A, Nielsen J N, Jorgensen S B, et al. Exercise signalling to glucose transport in skeletal muscle[J]. Proc Nutr Soc, 2004,63(2):211-216.
    • (2004) Proc Nutr Soc , vol.63 , Issue.2 , pp. 211-216
    • Richter, E.A.1    Nielsen, J.N.2    Jorgensen, S.B.3
  • 47
    • 33644670987 scopus 로고    scopus 로고
    • Insulin-stimulated glucose uptake does not require p38 mitogen-activated protein kinase in adipose tissue or skeletal muscle[J]
    • Turban S, Beardmore V A, Carr J M, et al. Insulin-stimulated glucose uptake does not require p38 mitogen-activated protein kinase in adipose tissue or skeletal muscle[J]. Diabetes, 2005,54 (11):3161-3168.
    • (2005) Diabetes , vol.54 , Issue.11 , pp. 3161-3168
    • Turban, S.1    Beardmore, V.A.2    Carr, J.M.3
  • 48
    • 15444367035 scopus 로고    scopus 로고
    • Activation of p38 MAP kinase enhances sensitivity of muscle glucose transport to insulin [J]
    • Geiger P C, Wright D C, Han D H, et al. Activation of p38 MAP kinase enhances sensitivity of muscle glucose transport to insulin [J]. Am J Physiol Endocrinol Metab, 2005,288(4):E782-788.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , Issue.4
    • Geiger, P.C.1    Wright, D.C.2    Han, D.H.3
  • 49
    • 2342599054 scopus 로고    scopus 로고
    • Exercise and myocyte enhancer factor 2 regulation in human skeletal muscle[J]
    • McGee S L, Hargreaves M. Exercise and myocyte enhancer factor 2 regulation in human skeletal muscle[J]. Diabetes, 2004,53(5):1208-1214.
    • (2004) Diabetes , vol.53 , Issue.5 , pp. 1208-1214
    • McGee, S.L.1    Hargreaves, M.2
  • 50
    • 33645028038 scopus 로고    scopus 로고
    • Exercise and skeletal muscle glucose transporter 4 expression: Molecular mechanisms[J]
    • McGee S L, Hargreaves M. Exercise and skeletal muscle glucose transporter 4 expression: molecular mechanisms[J]. Clin Exp Pharmacol Physiol, 2006,33(4):395-399.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , Issue.4 , pp. 395-399
    • McGee, S.L.1    Hargreaves, M.2
  • 51
    • 2342428466 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner[J]
    • de Alvaro C, Teruel T, Hernandez R, et al. Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner[J]. J Biol Chem, 2004,279(17):17070- 17078.
    • (2004) J Biol Chem , vol.279 , Issue.17 , pp. 17070-17078
    • de Alvaro, C.1    Teruel, T.2    Hernandez, R.3
  • 52
    • 33745769040 scopus 로고    scopus 로고
    • Mitochondrial dysfunction induces aberrant insulin signalling and glucose utilisation in murine C2C12 myotube cells[J]
    • Lim J H, Lee J I, Suh Y H, et al. Mitochondrial dysfunction induces aberrant insulin signalling and glucose utilisation in murine C2C12 myotube cells[J]. Diabetologia, 2006,49(8):1924-1936.
    • (2006) Diabetologia , vol.49 , Issue.8 , pp. 1924-1936
    • Lim, J.H.1    Lee, J.I.2    Suh, Y.H.3
  • 53
    • 30444440735 scopus 로고    scopus 로고
    • Regulation of skeletal muscle gene expression by p38 MAP kinases[J]
    • Lluis F, Perdiguero E, Nebreda A R, et al. Regulation of skeletal muscle gene expression by p38 MAP kinases[J]. Trends Cell Biol, 2006,16(1):36-44.
    • (2006) Trends Cell Biol , vol.16 , Issue.1 , pp. 36-44
    • Lluis, F.1    Perdiguero, E.2    Nebreda, A.R.3
  • 54
    • 0033548233 scopus 로고    scopus 로고
    • Stress-activated protein kinase-2/p38 and a rapamycin-sensitive pathway are required for C2C12 myogenesis [J]
    • Cuenda A, Cohen P. Stress-activated protein kinase-2/p38 and a rapamycin-sensitive pathway are required for C2C12 myogenesis [J]. J Biol Chem, 1999,274(4):4341-4346.
    • (1999) J Biol Chem , vol.274 , Issue.4 , pp. 4341-4346
    • Cuenda, A.1    Cohen, P.2
  • 55
    • 0033582459 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor[J]
    • Zetser A, Gredinger E, Bengal E. p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor[J]. J Biol Chem, 1999,274 (8):5193-5200.
    • (1999) J Biol Chem , vol.274 , Issue.8 , pp. 5193-5200
    • Zetser, A.1    Gredinger, E.2    Bengal, E.3
  • 56
    • 0034067079 scopus 로고    scopus 로고
    • p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps[J]
    • Wu Z, Woodring P J, Bhakta K S, et al. p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps[J]. Mol Cell Biol, 2000,20(11):3951-3964.
    • (2000) Mol Cell Biol , vol.20 , Issue.11 , pp. 3951-3964
    • Wu, Z.1    Woodring, P.J.2    Bhakta, K.S.3
  • 57
    • 0034528405 scopus 로고    scopus 로고
    • Myogenic differentiation requires signalling through both phosphatidylinositol 3-kinase and p38 MAP kinase[J]
    • Li Y, Jiang B, Ensign W Y, et al. Myogenic differentiation requires signalling through both phosphatidylinositol 3-kinase and p38 MAP kinase[J]. Cell Signal, 2000,12(11-12):751-757.
    • (2000) Cell Signal , vol.12 , Issue.11-12 , pp. 751-757
    • Li, Y.1    Jiang, B.2    Ensign, W.Y.3
  • 58
    • 1542350798 scopus 로고    scopus 로고
    • Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes[J]
    • Suelves M, Lluis F, Ruiz V, et al. Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes[J]. Embo J, 2004,23(2):365-375.
    • (2004) Embo J , vol.23 , Issue.2 , pp. 365-375
    • Suelves, M.1    Lluis, F.2    Ruiz, V.3
  • 59
    • 0020629380 scopus 로고
    • Involvement of a cytosolic carrier protein fraction in the microsomal metabolism of benzo(a) pyrene in rat liver[J]
    • Hanson-Painton O, Griffin M, Tang J. Involvement of a cytosolic carrier protein fraction in the microsomal metabolism of benzo(a) pyrene in rat liver[J]. Cancer Res, 1983,43(9):4198-4206.
    • (1983) Cancer Res , vol.43 , Issue.9 , pp. 4198-4206
    • Hanson-Painton, O.1    Griffin, M.2    Tang, J.3
  • 60
    • 0033168093 scopus 로고    scopus 로고
    • Post-translational control of the MEF2A transcriptional regulatory protein[J]
    • Ornatsky O I, Cox D M, Tangirala P, et al. Post-translational control of the MEF2A transcriptional regulatory protein[J]. Nucleic Acids Res, 1999,27(13):2646-2654.
    • (1999) Nucleic Acids Res , vol.27 , Issue.13 , pp. 2646-2654
    • Ornatsky, O.I.1    Cox, D.M.2    Tangirala, P.3
  • 61
    • 16344385453 scopus 로고    scopus 로고
    • E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription[J]
    • Lluis F, Ballestar E, Suelves M, et al. E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription[J]. Embo J, 2005,24(5):974-984.
    • (2005) Embo J , vol.24 , Issue.5 , pp. 974-984
    • Lluis, F.1    Ballestar, E.2    Suelves, M.3
  • 62
    • 3042763342 scopus 로고    scopus 로고
    • p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci [J]
    • Simone C, Forcales S V, Hill D A, et al. p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci [J]. Nat Genet, 2004,36(7):738-743.
    • (2004) Nat Genet , vol.36 , Issue.7 , pp. 738-743
    • Simone, C.1    Forcales, S.V.2    Hill, D.A.3
  • 63
    • 0042170212 scopus 로고    scopus 로고
    • Inhibition of p38 MAPK signaling promotes late stages of myogenesis[J]
    • Weston A D, Sampaio A V, Ridgeway A G, et al. Inhibition of p38 MAPK signaling promotes late stages of myogenesis[J]. J Cell Sci, 2003,116(Pt 14):2885-2893.
    • (2003) J Cell Sci , vol.116 , Issue.PART 14 , pp. 2885-2893
    • Weston, A.D.1    Sampaio, A.V.2    Ridgeway, A.G.3
  • 64
    • 14644400387 scopus 로고    scopus 로고
    • TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle[J]
    • Li Y P, Chen Y, John J, et al. TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle[J]. Faseb J, 2005,19(3):362-370.
    • (2005) Faseb J , vol.19 , Issue.3 , pp. 362-370
    • Li, Y.P.1    Chen, Y.2    John, J.3
  • 65
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of of nuclear receptors linked to adaptive thermogenesis [J]
    • Puigserver P, Wu Z, Park C, et al. A cold-inducible coactivator of of nuclear receptors linked to adaptive thermogenesis [J]. Cell, 1998,92(6):829-839.
    • (1998) Cell , vol.92 , Issue.6 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.3
  • 66
    • 0037102256 scopus 로고    scopus 로고
    • Transcriptional co-activator PGC-1 alpha drives the formation of slow- twitch muscle fibres[J]
    • Lin J, Wu H, Tarr P T, et al. 2002 Transcriptional co-activator PGC-1 alpha drives the formation of slow- twitch muscle fibres[J]. Nature, 418(6899):797-801.
    • (2002) Nature , vol.418 , Issue.6899 , pp. 797-801
    • Lin, J.1    Wu, H.2    Tarr, P.T.3
  • 67
    • 21244477127 scopus 로고    scopus 로고
    • Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway[J]
    • Akimoto T, Pohnert S C, Li P, et al. Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway[J]. J Biol Chem, 2005,280(20):19587-19593.
    • (2005) J Biol Chem , vol.280 , Issue.20 , pp. 19587-19593
    • Akimoto, T.1    Pohnert, S.C.2    Li, P.3
  • 68
    • 0038810035 scopus 로고    scopus 로고
    • An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle[J]
    • Handschin C, Rhee J, Lin J, et al. An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle[J]. Proc Natl Acad Sci USA, 2003,100 (12):7111-7116.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.12 , pp. 7111-7116
    • Handschin, C.1    Rhee, J.2    Lin, J.3
  • 69
    • 18244399631 scopus 로고    scopus 로고
    • Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPAR Coactivator-1[J]
    • Puigserver P, Rhee J, Lin J, et al. Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPAR Coactivator-1[J]. Molecular Cell, 2001,8(5):971-982.
    • (2001) Molecular Cell , vol.8 , Issue.5 , pp. 971-982
    • Puigserver, P.1    Rhee, J.2    Lin, J.3
  • 70
    • 0030846574 scopus 로고    scopus 로고
    • The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic-cells[J]
    • Macfarlane W, Smith S B, James R F, et al. The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic-cells[J]. J Biol Chem, 1997,272(33):20936-20944.
    • (1997) J Biol Chem , vol.272 , Issue.33 , pp. 20936-20944
    • Macfarlane, W.1    Smith, S.B.2    James, R.F.3
  • 71
    • 0033534620 scopus 로고    scopus 로고
    • Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells [J]
    • Macfarlane W M, McKinnon C M, Felton-Edkins Z A, et al. Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells [J]. J Biol Chem, 1999,274(2):1011-1016.
    • (1999) J Biol Chem , vol.274 , Issue.2 , pp. 1011-1016
    • Macfarlane, W.M.1    McKinnon, C.M.2    Felton-Edkins, Z.A.3
  • 72
    • 0033572844 scopus 로고    scopus 로고
    • Insulin stimulates pancreatic-duodenal homoeobox factor-1 (PDX1) DNA- binding activity and insulin promoter activity in pancreatic beta cells[J]
    • Wu H, MacFarlane W M, Tadayyon M, et al. Insulin stimulates pancreatic-duodenal homoeobox factor-1 (PDX1) DNA- binding activity and insulin promoter activity in pancreatic beta cells[J]. Biochem J, 1999,344 Pt 3:813-818.
    • (1999) Biochem J , vol.344 , Issue.PART 3 , pp. 813-818
    • Wu, H.1    MacFarlane, W.M.2    Tadayyon, M.3
  • 73
    • 0034717337 scopus 로고    scopus 로고
    • Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2[J]
    • Rafiq I, da Silva Xavier G, Hooper S, et al. Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2[J]. J Biol Chem, 2000, 275(21):15977-15984.
    • (2000) J Biol Chem , vol.275 , Issue.21 , pp. 15977-15984
    • Rafiq, I.1    da Silva Xavier, G.2    Hooper, S.3
  • 74
    • 0035097612 scopus 로고    scopus 로고
    • Insulinotropic hormone glucagon-like peptide 1 (GLP-1) activation of insulin gene promoter inhibited by p38 mitogen-activated protein kinase[J]
    • Kemp D M, Habener J F. Insulinotropic hormone glucagon-like peptide 1 (GLP-1) activation of insulin gene promoter inhibited by p38 mitogen-activated protein kinase[J]. Endocrinology, 2001,142(3):1179-1187.
    • (2001) Endocrinology , vol.142 , Issue.3 , pp. 1179-1187
    • Kemp, D.M.1    Habener, J.F.2
  • 75
    • 1642564596 scopus 로고    scopus 로고
    • The specific p38 mitogen-activated protein kinase pathway inhibitor FR167653 keeps insulitis benign in nonobese diabetic mice[J]
    • Ando H, Kurita S, Takamura T. The specific p38 mitogen-activated protein kinase pathway inhibitor FR167653 keeps insulitis benign in nonobese diabetic mice[J]. Life Sci, 2004,74(14): 1817-1827.
    • (2004) Life Sci , vol.74 , Issue.14 , pp. 1817-1827
    • Ando, H.1    Kurita, S.2    Takamura, T.3
  • 76
    • 12344323484 scopus 로고    scopus 로고
    • Type 2 diabetes-a matter of beta-cell life and death? [J]
    • Rhodes C J. Type 2 diabetes-a matter of beta-cell life and death? [J]. Science, 2005,307(5708):380-384.
    • (2005) Science , vol.307 , Issue.5708 , pp. 380-384
    • Rhodes, C.J.1
  • 77
    • 0032510838 scopus 로고    scopus 로고
    • Interleukin-1 beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases[J]
    • Larsen C M, Wadt K A, Juhl L F, et al. Interleukin-1 beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases[J]. J Biol Chem, 1998,273(24):15294-15300.
    • (1998) J Biol Chem , vol.273 , Issue.24 , pp. 15294-15300
    • Larsen, C.M.1    Wadt, K.A.2    Juhl, L.F.3
  • 78
    • 0035164537 scopus 로고    scopus 로고
    • Modulation of JNK and p38 stress activated protein kinases in isolated islets of Langerhans: Insulin as an autocrine survival signal[J]
    • Paraskevas S, Aikin R, Maysinger D, et al. Modulation of JNK and p38 stress activated protein kinases in isolated islets of Langerhans: insulin as an autocrine survival signal[J]. Ann Surg, 2001, 233(1):124-133.
    • (2001) Ann Surg , vol.233 , Issue.1 , pp. 124-133
    • Paraskevas, S.1    Aikin, R.2    Maysinger, D.3
  • 79
    • 0035877087 scopus 로고    scopus 로고
    • Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis[J]
    • Saldeen J, Lee J C, Welsh N. Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis[J]. Biochem Pharmacol, 2001,61(12):1561-1569.
    • (2001) Biochem Pharmacol , vol.61 , Issue.12 , pp. 1561-1569
    • Saldeen, J.1    Lee, J.C.2    Welsh, N.3
  • 80
    • 33746782577 scopus 로고    scopus 로고
    • Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic beta-cells[J]
    • Zhang S, Liu H, Liu J, et al. Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic beta-cells[J]. FEBS J, 2006,273 (16):3779-3791.
    • (2006) FEBS J , vol.273 , Issue.16 , pp. 3779-3791
    • Zhang, S.1    Liu, H.2    Liu, J.3
  • 81
    • 33644749322 scopus 로고    scopus 로고
    • Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: Many differences, few similarities[J]
    • Cnop M, Welsh N, Jonas J C, et al. Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities[J]. Diabetes, 2005,54 (Suppl 2):S97-107.
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 2
    • Cnop, M.1    Welsh, N.2    Jonas, J.C.3
  • 82
    • 0141785429 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase[J]
    • Ehses J A, Casilla V R, Doty T, et al. Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase[J]. Endocrinology, 2003,144(10):4433-4445.
    • (2003) Endocrinology , vol.144 , Issue.10 , pp. 4433-4445
    • Ehses, J.A.1    Casilla, V.R.2    Doty, T.3
  • 83
    • 0030908291 scopus 로고    scopus 로고
    • Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion[J]
    • Khoo S, Cobb M H. Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion[J]. Proc Natl Acad Sci USA, 1997,94(11):5599-5604.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.11 , pp. 5599-5604
    • Khoo, S.1    Cobb, M.H.2
  • 84
    • 0033602201 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase cascade is not required for the stimulation of insulin secretion from rat islets of Langerhans[J]
    • Burns C J, Howell S L, Jones P M, et al. The p38 mitogen-activated protein kinase cascade is not required for the stimulation of insulin secretion from rat islets of Langerhans[J]. Mol Cell Endocrinol, 1999,148(1-2):29-35.
    • (1999) Mol Cell Endocrinol , vol.148 , Issue.1-2 , pp. 29-35
    • Burns, C.J.1    Howell, S.L.2    Jones, P.M.3
  • 85
    • 1842855230 scopus 로고    scopus 로고
    • Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta[J]
    • Kuma Y, Campbell D G, Cuenda A. Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta[J]. Biochem J, 2004,379(Pt 1):133-139.
    • (2004) Biochem J , vol.379 , Issue.PART 1 , pp. 133-139
    • Kuma, Y.1    Campbell, D.G.2    Cuenda, A.3
  • 86
    • 33747725908 scopus 로고    scopus 로고
    • C/EBPalpha mediates induction of hepatic phosphoenolpyruvate carboxykinase by p38 mitogen-activated protein kinase[J]
    • Qiao L, Macdougald O A, Shao J. C/EBPalpha mediates induction of hepatic phosphoenolpyruvate carboxykinase by p38 mitogen-activated protein kinase[J]. J Biol Chem, 2006,281(34):24390-24397.
    • (2006) J Biol Chem , vol.281 , Issue.34 , pp. 24390-24397
    • Qiao, L.1    Macdougald, O.A.2    Shao, J.3
  • 87
    • 33745353794 scopus 로고    scopus 로고
    • Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity[J]
    • Wu J J, Roth R J, Anderson E J, et al. Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity[J]. Cell Metab, 2006,4(1):61-73.
    • (2006) Cell Metab , vol.4 , Issue.1 , pp. 61-73
    • Wu, J.J.1    Roth, R.J.2    Anderson, E.J.3
  • 88
    • 0035855905 scopus 로고    scopus 로고
    • CREB regulates hepatic gluconeogenesis through the coactivator PGC-1[J]
    • Heraig S, Long F, Jhala U S, et al. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1[J]. Nature, 2001,413 (6852):179-183.
    • (2001) Nature , vol.413 , Issue.6852 , pp. 179-183
    • Heraig, S.1    Long, F.2    Jhala, U.S.3
  • 89
    • 0036783554 scopus 로고    scopus 로고
    • p38 MAPK mediates acid-induced transcription of PEPCK in LLC-PK(1)-FBPase(+) cells[J]
    • Feifel E, Obexer P, Andratsch M, et al. p38 MAPK mediates acid-induced transcription of PEPCK in LLC-PK(1)-FBPase(+) cells[J]. Am J Physiol Renal Physiol, 2002,283(4):F678-688.
    • (2002) Am J Physiol Renal Physiol , vol.283 , Issue.4
    • Feifel, E.1    Obexer, P.2    Andratsch, M.3
  • 90
    • 0035977050 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: A potential role in the cardiac metabolic stress response[J]
    • Barger P M, Browning A C, Garner A N, et al. p38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: a potential role in the cardiac metabolic stress response[J]. J Biol Chem, 2001,276(48):44495-44501.
    • (2001) J Biol Chem , vol.276 , Issue.48 , pp. 44495-44501
    • Barger, P.M.1    Browning, A.C.2    Garner, A.N.3
  • 91
    • 0242516072 scopus 로고    scopus 로고
    • Regulation of microsomal triglyceride transfer protein gene by insulin in HepG2 cells: Roles of MAP-Kerk and MAPKp38[J]
    • Au W S, Kung H F, Lin M C. Regulation of microsomal triglyceride transfer protein gene by insulin in HepG2 cells: roles of MAP-Kerk and MAPKp38[J]. Diabetes, 2003,52(5):1073-1080.
    • (2003) Diabetes , vol.52 , Issue.5 , pp. 1073-1080
    • Au, W.S.1    Kung, H.F.2    Lin, M.C.3
  • 92
    • 20044368479 scopus 로고    scopus 로고
    • Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes[J]
    • Allister E M, Borradaile N M, Edwards J Y, et al. Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes[J]. Diabetes, 2005,54(6):1676-1683.
    • (2005) Diabetes , vol.54 , Issue.6 , pp. 1676-1683
    • Allister, E.M.1    Borradaile, N.M.2    Edwards, J.Y.3
  • 93
    • 0033538498 scopus 로고    scopus 로고
    • One-way cross-talk between p38 (MAPK) and p42/44 (MAPK). Inhibition of p38 (MAPK) induces low density lipoprotein receptor expression through activation of the p42/44 (MAPK) cascade[J]
    • Singh R P, Dhawan P, Golden C, et al. One-way cross-talk between p38 (MAPK) and p42/44 (MAPK). Inhibition of p38 (MAPK) induces low density lipoprotein receptor expression through activation of the p42/44 (MAPK) cascade[J]. J Biol Chem, 1999,274(28):19593-19600.
    • (1999) J Biol Chem , vol.274 , Issue.28 , pp. 19593-19600
    • Singh, R.P.1    Dhawan, P.2    Golden, C.3
  • 94
    • 0009870909 scopus 로고    scopus 로고
    • Inhibition of stress-activated p38 mitogen-activated protein kinase induces low-density lipoprotein receptor expression[J]
    • Mehta K D, Miller L. Inhibition of stress-activated p38 mitogen-activated protein kinase induces low-density lipoprotein receptor expression[J]. Trends Cardiovasc Med, 1999,9(7):201-205.
    • (1999) Trends Cardiovasc Med , vol.9 , Issue.7 , pp. 201-205
    • Mehta, K.D.1    Miller, L.2
  • 95
    • 0034910937 scopus 로고    scopus 로고
    • Tauroursodesoxycholate-induced choleresis involves p38 (MAPK) activation and translocation of the bile salt export pump in rats[J]
    • Kurz A K, Graf D, Schmitt M, et al. Tauroursodesoxycholate-induced choleresis involves p38 (MAPK) activation and translocation of the bile salt export pump in rats[J]. Gastroenterology, 2001, 121(2):407-419.
    • (2001) Gastroenterology , vol.121 , Issue.2 , pp. 407-419
    • Kurz, A.K.1    Graf, D.2    Schmitt, M.3
  • 96
    • 0842299393 scopus 로고    scopus 로고
    • Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase[J]
    • Kubitz R, Sutfels G, Kuhlkamp T, et al. Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase[J]. Gastroenterology, 2004,126 (2):541-553.
    • (2004) Gastroenterology , vol.126 , Issue.2 , pp. 541-553
    • Kubitz, R.1    Sutfels, G.2    Kuhlkamp, T.3
  • 97
    • 0034858012 scopus 로고    scopus 로고
    • Glutamine and cell signaling in liver[J]
    • discussion 2523S-2524S
    • Haussinger D, Graf D, Weiergraber O H. Glutamine and cell signaling in liver[J]. J Nutr, 2001,131(9 Suppl):2509S-14S; discussion 2523S-2524S.
    • (2001) J Nutr , vol.131 , Issue.9 SUPPL.
    • Haussinger, D.1    Graf, D.2    Weiergraber, O.H.3
  • 98
    • 18844383961 scopus 로고    scopus 로고
    • p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes [J]
    • Engel F B, Schebesta M, Duong M T, et al. p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes [J]. Genes Dev, 2005,19(10):1175-1187.
    • (2005) Genes Dev , vol.19 , Issue.10 , pp. 1175-1187
    • Engel, F.B.1    Schebesta, M.2    Duong, M.T.3
  • 99
    • 0031844392 scopus 로고    scopus 로고
    • Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy[J]
    • Nemoto S, Sheng Z, Lin A. Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy[J]. Mol Cell Biol, 1998,18(6):3518-3526.
    • (1998) Mol Cell Biol , vol.18 , Issue.6 , pp. 3518-3526
    • Nemoto, S.1    Sheng, Z.2    Lin, A.3
  • 100
    • 0034535088 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase plays an essential role in hypertrophic agonists, endothelin-1 and phenylephrine-induced cardiomyocyte hypertrophy [J]
    • Yue T L, Gu J L, Wang C, et al. Extracellular signal-regulated kinase plays an essential role in hypertrophic agonists, endothelin-1 and phenylephrine-induced cardiomyocyte hypertrophy [J]. J Biol Chem, 2000,275(48):37895-37901.
    • (2000) J Biol Chem , vol.275 , Issue.48 , pp. 37895-37901
    • Yue, T.L.1    Gu, J.L.2    Wang, C.3
  • 101
    • 0035834071 scopus 로고    scopus 로고
    • The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardlomyopathy[J]
    • Liao P, Georgakopoulos D, Kovacs A, et al. The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardlomyopathy[J]. Proc Natl Acad Sci USA, 2001,98(21):12283-12288.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.21 , pp. 12283-12288
    • Liao, P.1    Georgakopoulos, D.2    Kovacs, A.3
  • 102
    • 85047687695 scopus 로고    scopus 로고
    • The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis [J]
    • Zhang S, Weinheimer C, Courtois M, et al. The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis [J]. J Clin Invest, 2003,111(6):833-841.
    • (2003) J Clin Invest , vol.111 , Issue.6 , pp. 833-841
    • Zhang, S.1    Weinheimer, C.2    Courtois, M.3
  • 103
    • 4444381927 scopus 로고    scopus 로고
    • Regulation of glucose transporter expression in cardiac myocytes: P38 MAPK is a strong inducer of GLUT4[J]
    • Montessuit C, Rosenblatt-Velin N, Papageorgiou I, et al. Regulation of glucose transporter expression in cardiac myocytes: p38 MAPK is a strong inducer of GLUT4[J]. Cardiovasc Res, 2004, 64(1):94-104.
    • (2004) Cardiovasc Res , vol.64 , Issue.1 , pp. 94-104
    • Montessuit, C.1    Rosenblatt-Velin, N.2    Papageorgiou, I.3
  • 104
    • 0034973683 scopus 로고    scopus 로고
    • Activation of p38 MAPK induced by a multi-cycle ischaemic preconditioning protocol is associated with attenuated p38 MAPK activity during sustained ischaemia and reperfusion[J]
    • Marais E, Genade S, Huisamen B, et al. Activation of p38 MAPK induced by a multi-cycle ischaemic preconditioning protocol is associated with attenuated p38 MAPK activity during sustained ischaemia and reperfusion[J]. J Mol Cell Cardiol, 2001, 33:769-778.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 769-778
    • Marais, E.1    Genade, S.2    Huisamen, B.3
  • 105
    • 0036839541 scopus 로고    scopus 로고
    • LOX-1 inhibition in myocardial ischemia-reperfusion injury: Modulation of MMP-1 and inflammation[J]
    • Li D, Williams V, Liu L, et al. LOX-1 inhibition in myocardial ischemia-reperfusion injury: modulation of MMP-1 and inflammation[J]. Am J Physiol Heart Circ Physiol, 2002,283(5):H1795-1801.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , Issue.5
    • Li, D.1    Williams, V.2    Liu, L.3
  • 106
    • 0036164426 scopus 로고    scopus 로고
    • p38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation[J]
    • Gao F, Yue T L, Shi D W, et al. p38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation[J]. Cardiovasc Res, 2002,53(2):414-422.
    • (2002) Cardiovasc Res , vol.53 , Issue.2 , pp. 414-422
    • Gao, F.1    Yue, T.L.2    Shi, D.W.3
  • 107
    • 11244305854 scopus 로고    scopus 로고
    • Intracellular acidosis-activated p38 MAPK signaling and its essential role in cardiomyocyte hypoxic injury[J]
    • Zheng M, Reynolds C, Jo S H, et al. Intracellular acidosis-activated p38 MAPK signaling and its essential role in cardiomyocyte hypoxic injury[J]. Faseb J, 2005,19(1):109-111.
    • (2005) Faseb J , vol.19 , Issue.1 , pp. 109-111
    • Zheng, M.1    Reynolds, C.2    Jo, S.H.3
  • 108
    • 0031239584 scopus 로고    scopus 로고
    • Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart[J]
    • Weinbrenner C, Liu G S, Cohen M V, et al. Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart[J]. J Mol Cell Cardiol, 1997,29(9):2383- 2391.
    • (1997) J Mol Cell Cardiol , vol.29 , Issue.9 , pp. 2383-2391
    • Weinbrenner, C.1    Liu, G.S.2    Cohen, M.V.3
  • 109
    • 0034532277 scopus 로고    scopus 로고
    • SB 203580, an inhibitor of p38 MAPK, abolishes infarct-limiting effect of ischemic preconditioning in isolated rabbit hearts[J]
    • Nakano A, Cohen M V, Critz S, et al. SB 203580, an inhibitor of p38 MAPK, abolishes infarct-limiting effect of ischemic preconditioning in isolated rabbit hearts[J]. Basic Res Cardiol, 2000, 95(6):466-471.
    • (2000) Basic Res Cardiol , vol.95 , Issue.6 , pp. 466-471
    • Nakano, A.1    Cohen, M.V.2    Critz, S.3
  • 110
    • 0034537885 scopus 로고    scopus 로고
    • The p38 MAPK inhibitor, SB203580, abrogates ischaemic preconditioning in rat heart but timing of administration is critical[J]
    • Mocanu M M, Baxter G F, Yue Y, et al. The p38 MAPK inhibitor, SB203580, abrogates ischaemic preconditioning in rat heart but timing of administration is critical[J]. Basic Res Cardiol, 2000,95(6):472-478.
    • (2000) Basic Res Cardiol , vol.95 , Issue.6 , pp. 472-478
    • Mocanu, M.M.1    Baxter, G.F.2    Yue, Y.3
  • 111
    • 0033960626 scopus 로고    scopus 로고
    • Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: Evidence for involvement of p38 MAPK[J]
    • Nakano A, Baines C P, Kim S O, et al. Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: evidence for involvement of p38 MAPK[J]. Circ Res, 2000,86(2):144-151.
    • (2000) Circ Res , vol.86 , Issue.2 , pp. 144-151
    • Nakano, A.1    Baines, C.P.2    Kim, S.O.3
  • 112
    • 0035834815 scopus 로고    scopus 로고
    • p38 Triggers late preconditioning elicited by anisomycin in heart; involvement of NF-kappaB and iNOS[J]
    • Zhao T C, Taher M M, Valerie K C, et al. p38 Triggers late preconditioning elicited by anisomycin in heart; involvement of NF-kappaB and iNOS[J]. Circ Res, 2001,89(10):915-922.
    • (2001) Circ Res , vol.89 , Issue.10 , pp. 915-922
    • Zhao, T.C.1    Taher, M.M.2    Valerie, K.C.3
  • 113
    • 0035793337 scopus 로고    scopus 로고
    • Role of phasic dynamism of p38 mitogen-activated protein kinase activation in ischemic preconditioning of the canine heart[J]
    • Sanada S, Kitakaze M, Papst P J, et al. Role of phasic dynamism of p38 mitogen-activated protein kinase activation in ischemic preconditioning of the canine heart[J]. Circ Res, 2001,88(2):175-180.
    • (2001) Circ Res , vol.88 , Issue.2 , pp. 175-180
    • Sanada, S.1    Kitakaze, M.2    Papst, P.J.3
  • 114
    • 0034970996 scopus 로고    scopus 로고
    • Adenosine-induced late preconditioning in mouse hearts: Role of p38 MAP kinase and mitochondrial K(ATP) channels[J]
    • Zhao T C, Hines D S, Kukreja R C. Adenosine-induced late preconditioning in mouse hearts: role of p38 MAP kinase and mitochondrial K(ATP) channels[J]. Am J Physiol Heart Circ Physiol, 2001,280(3):H1278-1285.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280 , Issue.3
    • Zhao, T.C.1    Hines, D.S.2    Kukreja, R.C.3
  • 115
    • 0035695805 scopus 로고    scopus 로고
    • p38 MAPK activation triggers pharmacologically-induced beta-adrenergic preconditioning, but not ischaemic preconditioning[J]
    • Marais E, Genade S, Strijdom H, et al. p38 MAPK activation triggers pharmacologically-induced beta-adrenergic preconditioning, but not ischaemic preconditioning[J]. J Mol Cell Cardiol, 2001,33(12):2157-2177.
    • (2001) J Mol Cell Cardiol , vol.33 , Issue.12 , pp. 2157-2177
    • Marais, E.1    Genade, S.2    Strijdom, H.3
  • 116
    • 0036023646 scopus 로고    scopus 로고
    • p38 MAP kinase is a mediator of ischemic preconditioning in pigs [J]
    • Schulz R, Belosjorow S, Gres P, et al. p38 MAP kinase is a mediator of ischemic preconditioning in pigs [J]. Cardiovasc Res, 2002,55(3):690-700.
    • (2002) Cardiovasc Res , vol.55 , Issue.3 , pp. 690-700
    • Schulz, R.1    Belosjorow, S.2    Gres, P.3
  • 117
    • 0242637234 scopus 로고    scopus 로고
    • Comparison between ischaemic and anisomycin-induced preconditioning; role of p38 MAPK[J]
    • Lochner A, Genade S, Hattingh S, et al. Comparison between ischaemic and anisomycin-induced preconditioning; role of p38 MAPK[J]. Cardiovasc Drugs Ther, 2003,17(3):217-230.
    • (2003) Cardiovasc Drugs Ther , vol.17 , Issue.3 , pp. 217-230
    • Lochner, A.1    Genade, S.2    Hattingh, S.3
  • 118
    • 33646768213 scopus 로고    scopus 로고
    • Potentiation of a survival signal in the ischemic heart by resveratrol through p38 mitogen-activated protein kinase/mitogen- and stress-activated protein kinase 1/cAMP response element-binding protein signaling[J]
    • Das S, Tosaki A, Bagchi D, et al. Potentiation of a survival signal in the ischemic heart by resveratrol through p38 mitogen-activated protein kinase/mitogen- and stress-activated protein kinase 1/cAMP response element-binding protein signaling[J]. J Pharmacol Exp Ther, 2006,317(3):980-988.
    • (2006) J Pharmacol Exp Ther , vol.317 , Issue.3 , pp. 980-988
    • Das, S.1    Tosaki, A.2    Bagchi, D.3
  • 119
    • 0037590100 scopus 로고    scopus 로고
    • Ischemic preconditioning preserves connexin 43 phosphorylation during sustained ischemia in pig hearts in vivo[J]
    • Schulz R, Gres P, Skyschally A, et al. Ischemic preconditioning preserves connexin 43 phosphorylation during sustained ischemia in pig hearts in vivo[J]. Faseb J, 2003,17(10):1355-1357.
    • (2003) Faseb J , vol.17 , Issue.10 , pp. 1355-1357
    • Schulz, R.1    Gres, P.2    Skyschally, A.3
  • 120
    • 12844256390 scopus 로고    scopus 로고
    • Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo[J]
    • Martindale J J, Wall J A, Martinez-Longoria D M, et al. Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo[J]. J Biol Chem, 2005,280 (1):669-676.
    • (2005) J Biol Chem , vol.280 , Issue.1 , pp. 669-676
    • Martindale, J.J.1    Wall, J.A.2    Martinez-Longoria, D.M.3
  • 121
    • 28144443729 scopus 로고    scopus 로고
    • Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia- reperfusion[J]
    • Kaiser R A, Lyons J M, Duffy J Y, et al. Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia- reperfusion[J]. Am J Physiol Heart Circ Physiol, 2005,289:H2747-2751.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Kaiser, R.A.1    Lyons, J.M.2    Duffy, J.Y.3
  • 122
    • 0026333959 scopus 로고
    • Role of oxidized low density lipoprotein in atherogenesis[J]
    • Witztum J L, Steinberg D. Role of oxidized low density lipoprotein in atherogenesis[J]. J Clin Invest, 1991,88(6):1785-1792.
    • (1991) J Clin Invest , vol.88 , Issue.6 , pp. 1785-1792
    • Witztum, J.L.1    Steinberg, D.2
  • 123
    • 0036860896 scopus 로고    scopus 로고
    • Atherosclerosis in type 2 diabetes mellitus and insulin resistance: Mechanistic links and therapeutic targets[J]
    • Plutzky J, Viberti G, Haffner S. Atherosclerosis in type 2 diabetes mellitus and insulin resistance: mechanistic links and therapeutic targets[J]. J Diabetes Complications, 2002,16(6):401-415.
    • (2002) J Diabetes Complications , vol.16 , Issue.6 , pp. 401-415
    • Plutzky, J.1    Viberti, G.2    Haffner, S.3
  • 124
    • 3142510687 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis and diabetes mellitus [J]
    • Plutzky J. Inflammation in atherosclerosis and diabetes mellitus [J]. Rev Endocr Metab Disord, 2004,5(3):255-259.
    • (2004) Rev Endocr Metab Disord , vol.5 , Issue.3 , pp. 255-259
    • Plutzky, J.1
  • 125
    • 0028961110 scopus 로고
    • Diabetes and cardiovascular disease. The "common soil" hypothesis[J]
    • Stern M P. Diabetes and cardiovascular disease. The "common soil" hypothesis[J]. Diabetes, 1995,44(4):369-374.
    • (1995) Diabetes , vol.44 , Issue.4 , pp. 369-374
    • Stern, M.P.1
  • 126
    • 0034671604 scopus 로고    scopus 로고
    • Homocysteine stimulates nuclear factor kappaB activity and monocyte chemoattractant protein-1 expression in vascular smooth-muscle cells; a possible role for protein kinase C[J]
    • Wang G, Siow Y L, O K. Homocysteine stimulates nuclear factor kappaB activity and monocyte chemoattractant protein-1 expression in vascular smooth-muscle cells; a possible role for protein kinase C[J]. Biochem J, 2000,352(Pt 3):817-826.
    • (2000) Biochem J , vol.352 , Issue.PART 3 , pp. 817-826
    • Wang, G.1    Siow, Y.L.O.K.2
  • 127
    • 0035810980 scopus 로고    scopus 로고
    • Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: Implications for vascular disease[J]
    • Poddar R, Sivasubramanian N, DiBello P M, et al. Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: implications for vascular disease[J]. Circulation, 2001,103(22):2717-2723.
    • (2001) Circulation , vol.103 , Issue.22 , pp. 2717-2723
    • Poddar, R.1    Sivasubramanian, N.2    DiBello, P.M.3
  • 128
    • 0035122305 scopus 로고    scopus 로고
    • Homocysteine stimulates the expression of monocyte chemoattractant protein-1 in endothelial cells leading to enhanced monocyte chemotaxis[J]
    • Sung F L, Slow Y L, Wang G, et al. Homocysteine stimulates the expression of monocyte chemoattractant protein-1 in endothelial cells leading to enhanced monocyte chemotaxis[J]. Mol Cell Biochem, 2001,216(1-2):121-128.
    • (2001) Mol Cell Biochem , vol.216 , Issue.1-2 , pp. 121-128
    • Sung, F.L.1    Slow, Y.L.2    Wang, G.3
  • 129
    • 0036333434 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors in leukocyte trafficking[J]
    • Olson T S, Ley K. Chemokines and chemokine receptors in leukocyte trafficking[J]. Am J Physiol Regul Integr Comp Physiol, 2002,283(1):R7-28.
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283 , Issue.1
    • Olson, T.S.1    Ley, K.2
  • 130
    • 0032936517 scopus 로고    scopus 로고
    • The MKK6/p38 stress kinase cascade is critical for tumor necrosis factor-alpha-induced expression of monocyte-chemoattractant protein-1 in endothelial cells[J]
    • Goebeler M, Kilian K, Gillitzer R, et al. The MKK6/p38 stress kinase cascade is critical for tumor necrosis factor-alpha-induced expression of monocyte-chemoattractant protein-1 in endothelial cells[J]. Blood, 1999,93(3):857-865.
    • (1999) Blood , vol.93 , Issue.3 , pp. 857-865
    • Goebeler, M.1    Kilian, K.2    Gillitzer, R.3
  • 131
    • 0035437126 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment [J]
    • Marin V, Farnarier C, Gres S, et al. The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment [J]. Blood, 2001,98(3):667-673.
    • (2001) Blood , vol.98 , Issue.3 , pp. 667-673
    • Marin, V.1    Farnarier, C.2    Gres, S.3
  • 132
    • 0042878460 scopus 로고    scopus 로고
    • Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes[J]
    • Zeng X, Dai J, Remick D G, et al. Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes[J]. Circ Res, 2003,93(4):311-320.
    • (2003) Circ Res , vol.93 , Issue.4 , pp. 311-320
    • Zeng, X.1    Dai, J.2    Remick, D.G.3
  • 133
    • 0345327683 scopus 로고    scopus 로고
    • Chylomicron remnants induce monocyte chemoattractant protein-1 expression via p38 MAPK activation in vascular smooth muscle cells[J]
    • Domoto K, Taniguchi T, Takaishi H, et al. Chylomicron remnants induce monocyte chemoattractant protein-1 expression via p38 MAPK activation in vascular smooth muscle cells[J]. Atherosclerosis, 2003,171(2):193-200.
    • (2003) Atherosclerosis , vol.171 , Issue.2 , pp. 193-200
    • Domoto, K.1    Taniguchi, T.2    Takaishi, H.3
  • 134
    • 3142767560 scopus 로고    scopus 로고
    • Myocyte enhancer factor 2 mediates vascular inflammation via the p38-dependent pathway[J]
    • Suzuki E, Salonaka H, Nishimatsu H, et al. Myocyte enhancer factor 2 mediates vascular inflammation via the p38-dependent pathway[J]. Circ Res, 2004,95(1):42-49.
    • (2004) Circ Res , vol.95 , Issue.1 , pp. 42-49
    • Suzuki, E.1    Salonaka, H.2    Nishimatsu, H.3
  • 135
    • 0842278630 scopus 로고    scopus 로고
    • Activation of discoidin domain receptor 1 isoform b with collagen up-regulates chemokine production in human macrophages: Role of p38 mitogen-activated protein kinase and NF-kappa B[J]
    • Matsuyama W, Wang L, Farrar W L, et al. Activation of discoidin domain receptor 1 isoform b with collagen up-regulates chemokine production in human macrophages: role of p38 mitogen-activated protein kinase and NF-kappa B[J]. J Immunol, 2004,172 (4):2332-2340.
    • (2004) J Immunol , vol.172 , Issue.4 , pp. 2332-2340
    • Matsuyama, W.1    Wang, L.2    Farrar, W.L.3
  • 136
    • 0035863864 scopus 로고    scopus 로고
    • Signal transduction involved in MCP-1-mediated monocytic transendothelial migration [J]
    • Cambien B, Pomeranz M, Millet M A, et al. Signal transduction involved in MCP-1-mediated monocytic transendothelial migration [J]. Blood, 2001,97(2):359-366.
    • (2001) Blood , vol.97 , Issue.2 , pp. 359-366
    • Cambien, B.1    Pomeranz, M.2    Millet, M.A.3
  • 137
    • 0035844243 scopus 로고    scopus 로고
    • Distinct signaling pathways for MCP-1-dependent integrin activation and chemotaxis[J]
    • Ashida N, Arai H, Yamasaki M, et al. Distinct signaling pathways for MCP-1-dependent integrin activation and chemotaxis[J]. J Biol Chem, 2001,276(19):16555-16560.
    • (2001) J Biol Chem , vol.276 , Issue.19 , pp. 16555-16560
    • Ashida, N.1    Arai, H.2    Yamasaki, M.3
  • 138
    • 0030043420 scopus 로고    scopus 로고
    • Early signal transduction by the receptor to the chemokine monocyte chemolactic protein-1 in a murine T cell hybrid [J]
    • Dubois P M, Palmer D, Webb M L, et al. Early signal transduction by the receptor to the chemokine monocyte chemolactic protein-1 in a murine T cell hybrid [J]. J Immunol, 1996,156(4):1356-1361.
    • (1996) J Immunol , vol.156 , Issue.4 , pp. 1356-1361
    • Dubois, P.M.1    Palmer, D.2    Webb, M.L.3
  • 139
    • 0347994947 scopus 로고    scopus 로고
    • Soluble fractalkine prevents monocyte chemoattractant protein-1-induced monocyte migration via inhibition of stress-activated protein kinase 2/p38 and matrix metalloproteinase activities[J]
    • Vitale S, Schmid-Alliana A, Breuil V, et al. Soluble fractalkine prevents monocyte chemoattractant protein-1-induced monocyte migration via inhibition of stress-activated protein kinase 2/p38 and matrix metalloproteinase activities[J]. J Immunol, 2004, 172(1):585-592.
    • (2004) J Immunol , vol.172 , Issue.1 , pp. 585-592
    • Vitale, S.1    Schmid-Alliana, A.2    Breuil, V.3
  • 140
    • 0037927961 scopus 로고    scopus 로고
    • Interaction of discoidin domain receptor 1 isoform b (DDR1b) with collagen activates p38 mitogen-activated protein kinase and promotes differentiation of macrophages[J]
    • Matsuyama W, Kamohara H, Galligan C, et al. Interaction of discoidin domain receptor 1 isoform b (DDR1b) with collagen activates p38 mitogen-activated protein kinase and promotes differentiation of macrophages[J]. Faseb J, 2003,17(10):1286-1288.
    • (2003) Faseb J , vol.17 , Issue.10 , pp. 1286-1288
    • Matsuyama, W.1    Kamohara, H.2    Galligan, C.3
  • 141
    • 0141727773 scopus 로고    scopus 로고
    • High glucose-mediated effects on endothelial cell proliferation occur via p38 MAP kinase [J]
    • McGinn S, Saad S, Poronnik P, et al. High glucose-mediated effects on endothelial cell proliferation occur via p38 MAP kinase [J]. Am J Physiol Endocrinol Metab, 2003,285(4):E708-717.
    • (2003) Am J Physiol Endocrinol Metab , vol.285 , Issue.4
    • McGinn, S.1    Saad, S.2    Poronnik, P.3
  • 142
    • 20444385832 scopus 로고    scopus 로고
    • Activation of p38 has opposing effects on the proliferation and migration of endothelial cells[J]
    • McMullen M E, Bryant P W, Glembotski C C, et al. Activation of p38 has opposing effects on the proliferation and migration of endothelial cells[J]. J Biol Chem, 2005,280(22):20995-21003.
    • (2005) J Biol Chem , vol.280 , Issue.22 , pp. 20995-21003
    • McMullen, M.E.1    Bryant, P.W.2    Glembotski, C.C.3
  • 143
    • 33646368397 scopus 로고    scopus 로고
    • Up-regulalion of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells[J]
    • Shen Y H, Zhang L, Gan Y, et al. Up-regulalion of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells[J]. J Biol Chem, 2006,281(12):7727-7736.
    • (2006) J Biol Chem , vol.281 , Issue.12 , pp. 7727-7736
    • Shen, Y.H.1    Zhang, L.2    Gan, Y.3
  • 144
    • 20144371342 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase downregulates endothelial progenitor cells[J]
    • Seeger F H, Haendeler J, Walter D H, et al. p38 mitogen-activated protein kinase downregulates endothelial progenitor cells[J]. Circulation, 2005,111(19):1184-1191.
    • (2005) Circulation , vol.111 , Issue.19 , pp. 1184-1191
    • Seeger, F.H.1    Haendeler, J.2    Walter, D.H.3
  • 145
    • 0037625636 scopus 로고    scopus 로고
    • Role of JNK, p38, and ERK in platelet-derived growth factor-induced vascular proliferation, migration, and gene expression[J]
    • Zhan Y, Kim S, Izumi Y, et al. Role of JNK, p38, and ERK in platelet-derived growth factor-induced vascular proliferation, migration, and gene expression[J]. Arterioscler Thromb Vasc Biol, 2003,23(5):795-801.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , Issue.5 , pp. 795-801
    • Zhan, Y.1    Kim, S.2    Izumi, Y.3
  • 147
    • 0030699447 scopus 로고    scopus 로고
    • Pioglitazone reduces smooth muscle cell density of rat carotid arterial intima induced by balloon catheterization[J]
    • Igarashi M, Takeda Y, Ishibashi N, et al. Pioglitazone reduces smooth muscle cell density of rat carotid arterial intima induced by balloon catheterization[J]. Horm Metab Res, 1997,29(9):444-449.
    • (1997) Horm Metab Res , vol.29 , Issue.9 , pp. 444-449
    • Igarashi, M.1    Takeda, Y.2    Ishibashi, N.3
  • 148
    • 8344254327 scopus 로고    scopus 로고
    • Altered PDGF-BB-induced p38 MAP kinase activation in diabetic vascular smooth muscle cells: Roles of protein kinase C-delta[J]
    • Yamaguchi H, Igarashi M, Hirata A, et al. Altered PDGF-BB-induced p38 MAP kinase activation in diabetic vascular smooth muscle cells: roles of protein kinase C-delta[J]. Arterioscler Thromb Vasc Biol, 2004,24(11):2095-2101.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , Issue.11 , pp. 2095-2101
    • Yamaguchi, H.1    Igarashi, M.2    Hirata, A.3
  • 149
    • 26844460177 scopus 로고    scopus 로고
    • Cholesterol is the major component of native lipoproteins activating the p38 mitogen-activated protein kinases[J]
    • Dobreva I, Zschornig O, Waeber G, et al. Cholesterol is the major component of native lipoproteins activating the p38 mitogen-activated protein kinases[J]. Biol Chem, 2005,386(9):909-918.
    • (2005) Biol Chem , vol.386 , Issue.9 , pp. 909-918
    • Dobreva, I.1    Zschornig, O.2    Waeber, G.3
  • 150
    • 0035933127 scopus 로고    scopus 로고
    • Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members [J]
    • Surapisitchat J, Hoefen R J, Pi X, et al. Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members [J]. Proc Natl Acad Sci USA, 2001,98(11):6476-6481.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.11 , pp. 6476-6481
    • Surapisitchat, J.1    Hoefen, R.J.2    Pi, X.3
  • 151
    • 0344304814 scopus 로고    scopus 로고
    • p38 MAPK inhibitors ameliorate target organ damage in hypertension: Part 1. p38 MAPK-dependent endothelial dysfunction and hypertension [J]
    • Ju H, Behm D J, Nerurkar S, et al. p38 MAPK inhibitors ameliorate target organ damage in hypertension: Part 1. p38 MAPK-dependent endothelial dysfunction and hypertension [J]. J Pharmacol Exp Ther, 2003,307(3):932-938.
    • (2003) J Pharmacol Exp Ther , vol.307 , Issue.3 , pp. 932-938
    • Ju, H.1    Behm, D.J.2    Nerurkar, S.3
  • 152
    • 0034596279 scopus 로고    scopus 로고
    • Cholesterol modulates vascular reactivity to endothelin-1 by stimulating a pro-inflammatory pathway[J]
    • Paris D, Town T, Humphrey J, et al. Cholesterol modulates vascular reactivity to endothelin-1 by stimulating a pro-inflammatory pathway[J]. Biochem Biophys Res Commun, 2000,274(2): 553-558.
    • (2000) Biochem Biophys Res Commun , vol.274 , Issue.2 , pp. 553-558
    • Paris, D.1    Town, T.2    Humphrey, J.3
  • 153
    • 0033949329 scopus 로고    scopus 로고
    • Evidence for modulation of smooth muscle force by the p38 MAP kinase/HSP27 pathway[J]
    • Yamboliev I A, Hedges J C, Mutnick J L, et al. Evidence for modulation of smooth muscle force by the p38 MAP kinase/HSP27 pathway[J]. Am J Physiol Heart Circ Physiol, 2000,278(6):H1899-1907.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278 , Issue.6
    • Yamboliev, I.A.1    Hedges, J.C.2    Mutnick, J.L.3
  • 154
    • 0032693770 scopus 로고    scopus 로고
    • Possible involvement of heat shock protein 25 in the angiotensin II-induced glomerular mesangial cell contraction via p38 MAP kinase[J]
    • Muller E, Burger-Kentischer A, Neuhofer W, et al. Possible involvement of heat shock protein 25 in the angiotensin II-induced glomerular mesangial cell contraction via p38 MAP kinase[J]. J Cell Physiol, 1999,181(3):462-469.
    • (1999) J Cell Physiol , vol.181 , Issue.3 , pp. 462-469
    • Muller, E.1    Burger-Kentischer, A.2    Neuhofer, W.3
  • 155
    • 0033864719 scopus 로고    scopus 로고
    • p38 MAP kinase pathway regulates angiotensin II-induced contraction of rat vascular smooth muscle[J]
    • Meloche S, Landry J, Huot J, et al. p38 MAP kinase pathway regulates angiotensin II-induced contraction of rat vascular smooth muscle[J]. Am J Physiol Heart Circ Physiol, 2000,279(2):H741-751.
    • (2000) Am J Physiol Heart Circ Physiol , vol.279 , Issue.2
    • Meloche, S.1    Landry, J.2    Huot, J.3
  • 156
    • 0035571571 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinases by endothelin and noradrenaline in small arteries, regulation by calcium influx and tyrosine kinases, and their role in contraction[J]
    • Ohanian J, Cunliffe P, Ceppi E, et al. Activation of p38 mitogen-activated protein kinases by endothelin and noradrenaline in small arteries, regulation by calcium influx and tyrosine kinases, and their role in contraction[J]. Arterioscler Thromb Vase Biol, 2001,21(12):1921-1927.
    • (2001) Arterioscler Thromb Vase Biol , vol.21 , Issue.12 , pp. 1921-1927
    • Ohanian, J.1    Cunliffe, P.2    Ceppi, E.3


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