Co-treatment with dexamethasone and octanoate induces adipogenesis in 3T3-L1 cells

Cell Biology International

Volumn 28, Issue 3, 2004, Pages 209-216

  Takenouchi, Takato ^a   Takayama, Yoshiharu ^b   Takezawa, Toshiaki ^a  

^a NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^b NATIONAL INSTITUTE OF LIVESTOCK AND GRASSLAND SCIENCE   (Japan)

Author keywords

3T3 L1 cells; Adipogenesis; Dexamethasone; Octanoate; p38 MAP kinase inhibitor

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CAVEOLIN 1; DEXAMETHASONE; GLUCOSE; INSULIN; ISOBUTYLMETHYLXANTHINE; MEDIUM CHAIN FATTY ACID; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; OCTANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STIMULATION; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SPECIFICITY; LIPID STORAGE; LIPOGENESIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR UPREGULATION;

EID: 1242338174     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2003.11.020     Document Type: Article

References (27)

1. Abumrad N.A., Park J.H., Park C.R. Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. J Biol Chem. 259:1984;8945-8953.
2. Amri E.Z., Ailhaud G., Grimaldi P.A. Fatty acids as signal transducing molecules: involvement in the differentiation of preadipose to adipose cells. J Lipid Res. 35:1994;930-937.
3. Amri E.Z., Bertrand B., Ailhaud G., Grimaldi P. Regulation of adipose cell differentiation. I. Fatty acids are inducers of the aP2 gene expression. J Lipid Res. 32:1991;1449-1456.
4. Aso H., Abe H., Nakajima I., Ozutsumi K., Yamaguchi T., Takamori Y., et al. A preadipocyte clonal line from bovine intramuscular adipose tissue: nonexpression of GLUT-4 protein during adipocyte differentiation. Biochem Biophys Res Commun. 213:1995;369-375.
5. Bach A.C., Ingenbleek Y., Frey A. The usefulness of dietary medium-chain triglycerides in body weight control: fact or fancy? J Lipid Res. 37:1996;708-726.
6. Christensen E., Hagve T.A., Gronn M., Christophersen B.O. β-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. Biochim Biophys Acta. 1004:1989;187-195.
7. Cuenda A., Rouse J., Doza Y.N., Meier R., Cohen P., Gallagher T.F., et al. SB 203580 is a specific inhibitor of a MAP kinase homologue that is stimulated by cellular stresses and interleukin-1. FEBS Lett. 364:1995;229-233.
8. Ding S., Mersmann H.J. Fatty acids modulate porcine adipocyte differentiation and transcripts for transcription factors and adipocyte-characteristic proteins. J Nutr Biochem. 12:2001;101-108.
9. Engelman J.A., Berg A.H., Lewis R.Y., Lin A., Lisanti M.P., Scherer P.E. Constitutively active mitogen-activated protein kinase kinase 6(MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis. J Biol Chem. 274:1999;35630-35638.
10. Engelman J.A., Lisanti M.P., Scherer P.E. Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis. J Biol Chem. 273:1998;32111-32120.
11. Green H., Kehinde O. An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell. 5:1975;19-27.
12. Gregoire F.M., Smas C.M., Sul H.S. Understanding adipocyte differentiation. Physiol Rev. 78:1998;783-809.
13. Guo W., Choi J.K., Kirkland J.L., Corkey B.E., Hamilton J.A. Esterification of free fatty acids in adipocytes: a comparison between octanoate and oleate. Biochem J. 349:2000;463-471.
14. Han J., Farmer S.R., Kirkland J.L., Corkey B.E., Yoon R., Pirtskhalava T., et al. Octanoate attenuates adipogenesis in 3T3-L1 preadipocytes. J Nutr. 132:2002;904-910.
15. MacDougald O.A., Lane M.D. Transcriptional regulation of gene expression during adipocyte differentiation. Annu Rev Biochem. 64:1995;345-373.
16. Morikawa M., Nixon T., Green H. Growth hormone and the adipose conversion of 3T3 cells. Cell. 29:1982;783-789.
17. Obata T., Brown G.E., Yaffe M.B. MAP kinase pathways activated by stress: the p38 MAPK pathway. Crit Care Med. 28:2000;N67-077.
18. Olson J.E., Evers J.A., Holtzman D. Astrocyte volume regulation and ATP and phosphocreatine concentrations after exposure to salicylate, ammonium, and fatty acids. Metab Brain Dis. 7:1992;183-196.
19. Papamandjaris A.A., MacDougall D.E., Jones P.J. Medium chain fatty acid metabolism and energy expenditure: obesity treatment implications. Life Sci. 62:1998;1203-1215.
20. Sato K., Nakanishi N., Mitsumoto M. Culture conditions supporting adipose conversion of stromal-vascular cells from bovine intramuscular adipose tissues. J Vet Med Sci. 58:1996;1073-1078.
21. Scherer P.E., Lewis R.Y., Volonte D., Engelman J.A., Galbiati F., Couet J., et al. Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo. J Biol Chem. 272:1997;29337-29346.
22. Schoonjans K., Watanabe M., Suzuki H., Mahfoudi A., Krey G., Wahli W., et al. Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter. J Biol Chem. 270:1995;19269-19276.
23. Stremmel W., Pohl L., Ring A., Herrmann T. A new concept of cellular uptake and intracellular trafficking of long-chain fatty acids. Lipids. 36:2001;981-989.
24. Student A.K., Hsu R.Y., Lane M.D. Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes. J Biol Chem. 255:1980;4745-4750.
25. Sweeney G., Somwar R., Ramlal T., Volchuk A., Ueyama A., Klip A. An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes. J Biol Chem. 274:1999;10071-10078.
26. Tontonoz P., Hu E., Spiegelman B.M. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell. 79:1994;1147-1156.
27. Wang X.Z., Ron D. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase. Science. 272:1996;1347-1349.