Glucose-stimulated preproinsulin gene expression and nuclear trans- location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2

Journal of Biological Chemistry

Volumn 275, Issue 21, 2000, Pages 15977-15984

  Rafiq, Imran ^a   Da Silva Xavier, Gabriela ^a   Hooper, Steven ^a,b   Rutter, Guy A ^a  

^a SCHOOL OF MEDICAL SCIENCES   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; HOMEODOMAIN PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL KINASE; PREPROINSULIN; STRESS ACTIVATED PROTEIN KINASE; WORTMANNIN;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; CELL NUCLEUS; CHROMONES; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GLUCOSE; HOMEODOMAIN PROTEINS; IMIDAZOLES; ISLETS OF LANGERHANS; MAP KINASE KINASE 6; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROINSULIN; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C; PROTEIN PRECURSORS; PYRIDINES; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSFECTION;

EID: 0034717337     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.21.15977     Document Type: Article

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