Adenosine-induced late preconditioning in mouse hearts: Role of p38 MAP kinase and mitochondrial KATP channels

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 3 49-3, 2001, Pages

  Zhao, Ting C ^a   Hines, Denise S ^a   Kukreja, Rakesh C ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine; ATP sensivitive potassium channel; Ischemia; Mitogen activated protein; Reperfusion myocardial infarction; Signaling transduction

Indexed keywords

2 CHLORO 6 N CYCLOPENTYLADENOSINE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 5 HYDROXYDECANOIC ACID; ADENOSINE; ADENOSINE A1 RECEPTOR; DIMETHYL SULFOXIDE; GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE; POTASSIUM CHANNEL; TYROSINE KINASE RECEPTOR;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HEART INFARCTION PREVENTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0034970996     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.3.h1278     Document Type: Article

References (38)

1. Inhibition of the cardiac p38-MAPK pathway by SB-203580 delays ischemic cell death
2. Characterisation of the infarct-limiting effect of delayed preconditioning: Time course and dose-dependency studies in rabbit myocardium
3. Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning
4. 1 receptor activation
5. Second window of ischemic preconditioning is mediated by opening of ATP-sensitive potassium channels in the rabbit heart
6. + channels in rabbit heart
7. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures
8. Diversity in function and regulation of MAP kinase pathways
9. Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart: p38/RK MAPK and c-Jun N-terminal kinases are activated by ischemia/reperfusion
10. Adenosine A(1) receptor induced delayed preconditioning in rabbits: Induction of p38 mitogen-activated protein kinase activation and hsp27 phosphorylation via a tyrosine kinase- and protein kinase C-dependent mechanism
11. A new MAP kinase targeted by endotoxin and hyperosmolarity in mamalian cells
12. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by adenosine in the perfused rat heart
13. ATP-sensitive potassium channel mediates delayed ischemic protection by heat stress in rabbit heart
14. HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress
15. Genistein, a tyrosine kinase inhibitor, blocks the "second window of protection" 48 h after ischemic preconditioning in the rabbit
16. Stress- and mitogen-induced phosphorylation of the small heat shock protein Hsp25 by MAPKAP kinase 2 is not essential for chaperone properties and cellular thermoresistance
17. Interleukin-1β regulation of inducible nitric oxide synthase and cyclooxygenase-2 involves the p42/44 and p38 MAPK signaling pathways in cardiac myocytes
18. Induction of Chinese hamster HSP27 gene expression in mouse cells confers resistance to heat shock. HSP27 stabilization of the microfilament organization
19. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart
20. Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion
21. Modulation of the heat-induced activation of mitogen-activated protein (MAP) kinase by quercetin
22. Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts
23. Ischemic preconditioning triggers tyrosine kinase signaling: A potential role for MAPKAP kinase 2
24. Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase
25. ATP channels mediate late preconditioning against infarction produced by monophosphoryl lipid A
26. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
27. ATP channel induces early and delayed cardioprotective effect: Role of nitric oxide
28. Tyrosine kinase signaling in action potential shortening and expression of HSP72 in late preconditioning
29. Opening of mitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals
30. Myocardial ischemic tolerance following heat stress is abolished by ATP-sensitive potassium channel blockade
31. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
32. Translocation of HSP27 to sarcomere induced by ischemic preconditioning in isolated rat hearts
33. Activation of mitochondrial ATP-dependent potassium channels by nitric oxide
34. ATP channel elicits late preconditioning against myocardial infarction via protein kinase C signaling pathway
35. 1 selective agonist, 2-cyclopentyladenosine (CCPA), causes a sustained limitation of infarct size in rabbits
36. Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart
37. Myocardial ischemia/reperfusion injury in the inducible nitric oxide synthase knockout mice
38. 1 receptors: Evidence from gene knockout mice