A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation

Journal of Biological Chemistry

Volumn 277, Issue 52, 2002, Pages 50386-50395

  Somwar, Romel ^a,b   Koterski, Sandra ^c   Sweeney, Gary ^a   Sciotti, Richard ^c   Djuric, Stevan ^c   Berg, Cathy ^c   Trevillyan, James ^c   Scherer, Philipp E ^d   Rondinone, Christina M ^c   Klip, Amira ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c ABBOTT LABORATORIES   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; GLUCOSE; INSULIN;

ADIOCYTES;

PROTEINS;

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; A 291077; A 304000; AZULENE DERIVATIVE; CYTOCHALASIN B; FORSKOLIN; GLUCOSE TRANSPORTER 4; GLUTAMINE; INDINAVIR; INSULIN; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL STRAIN 3T3; CELL SURFACE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; GLUCOSE TRANSPORT; IC 50; MYOTUBE; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT;

3T3 CELLS; ADIPOCYTES; ANIMALS; BIOLOGICAL TRANSPORT; CLONING, MOLECULAR; ENZYME INHIBITORS; GENE LIBRARY; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; HUMANS; IMIDAZOLES; INSULIN; L CELLS (CELL LINE); MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; MUSCLE, SKELETAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLYMERASE CHAIN REACTION; PROTEIN TRANSPORT; PYRIDINES; RATS; TRANSFECTION;

ANIMALIA;

EID: 0347721775     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205277200     Document Type: Article

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