Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: Evidence for involvement of p38 MAPK

Circulation Research

Volumn 86, Issue 2, 2000, Pages 144-151

  Nakano, Atsushi ^a   Baines, Christopher P ^a   Kim, Sung O ^c   Pelech, Steven L ^c   Downey, James M ^a   Cohen, Michael V ^a,b   Critz, Stuart D ^a  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Anisomycin; Ischemic preconditioning; JNK; MAPKAPK2; P38 MAPK

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 8 (4 SULFOPHENYL)THEOPHYLLINE; ANISOMYCIN; GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHENYLISOPROPYLADENOSINE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART MUSCLE BIOPSY; HEART MUSCLE ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; RABBIT;

EID: 0033960626     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.86.2.144     Document Type: Article

References (5)

1. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. 1986; 74:1124-1136.
2. Ytrehus K, Liu Y, Downey JM. Preconditioning protects ischemic rabbit heart by protein kinase C activation. Am J Physiol. 1994;266: H1145-H1152.
3. Ping P, Zhang J, Qiu Y, Tang X-L, Manchikalapudi S, Cao X, Bolli R. Ischemic preconditioning induces selective translocation of protein kinase C isoforms ε and η in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity. Circ Res. 1997;81: 404-414.
4. Armstrong SC, Delacey M, Ganote CE. Phosphorylation state of hsp27 and p38 MAPK during preconditioning and protein phosphatase inhibitor protection of rabbit cardiomyocytes. J Mol Cell Cardiol. 1999;31: 555-567.
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