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Volumn 13, Issue 4, 2006, Pages 1069-1084

Calcium-dependent growth regulation of small cell lung cancer cells by neuropeptides

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 1 [3,5 DICHLORO 4 (4 CHLOROBENZOYL)BENZYL] 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; AUTOANTIBODY; BOMBESIN; CISPLATIN; ETOPOSIDE; GASTRIN RELEASING PEPTIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE; NEUROPEPTIDE; PHOSPHOLIPASE C BETA1; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE; SUBSTANCE P DERIVATIVE;

EID: 33846846701     PISSN: 13510088     EISSN: None     Source Type: Journal    
DOI: 10.1677/erc.1.01302     Document Type: Review
Times cited : (19)

References (134)
  • 2
    • 0024292722 scopus 로고    scopus 로고
    • Almoguera C, Shibata D, Forrester K, Martin J, Arnheim N & Perucho M 1988 Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell 53 549-554.
    • Almoguera C, Shibata D, Forrester K, Martin J, Arnheim N & Perucho M 1988 Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell 53 549-554.
  • 3
    • 0036257483 scopus 로고    scopus 로고
    • Nuclear translocation of cell adhesion kinase beta/proline-rich tyrosine kinase 2
    • Aoto H, Sasaki H, Ishino M & Sasaki T 2002 Nuclear translocation of cell adhesion kinase beta/proline-rich tyrosine kinase 2. Cell Structure and Function 27 47-61.
    • (2002) Cell Structure and Function , vol.27 , pp. 47-61
    • Aoto, H.1    Sasaki, H.2    Ishino, M.3    Sasaki, T.4
  • 5
    • 23344446919 scopus 로고    scopus 로고
    • Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway
    • Basile JR, Afkhami T & Gutkind JS 2005 Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway. Molecular and Cellular Biology 25 6889-6898.
    • (2005) Molecular and Cellular Biology , vol.25 , pp. 6889-6898
    • Basile, J.R.1    Afkhami, T.2    Gutkind, J.S.3
  • 6
    • 0032032681 scopus 로고    scopus 로고
    • Expression of catalytically inactive phospholipase Cβ disrupts phospholipase Cβ and mitogen-activated protein kinase signaling and inhibits small cell lung cancer growth
    • Beekman A, Helfrich B, Bunn PA, Jr & Heasley LE 1998 Expression of catalytically inactive phospholipase Cβ disrupts phospholipase Cβ and mitogen-activated protein kinase signaling and inhibits small cell lung cancer growth. Cancer Research 58 910-913.
    • (1998) Cancer Research , vol.58 , pp. 910-913
    • Beekman, A.1    Helfrich, B.2    Bunn Jr, P.A.3    Heasley, L.E.4
  • 8
    • 0037451803 scopus 로고    scopus 로고
    • GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila
    • Bernards A 2003 GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. Biochimica et Biophysica Acta 1603 47-82.
    • (2003) Biochimica et Biophysica Acta , vol.1603 , pp. 47-82
    • Bernards, A.1
  • 13
    • 0036118399 scopus 로고    scopus 로고
    • Matrix metalloproteinases and matrix metalloproteinase inhibitors in lung cancer
    • Bonomi P 2002 Matrix metalloproteinases and matrix metalloproteinase inhibitors in lung cancer. Seminars in Oncology 29 78-86.
    • (2002) Seminars in Oncology , vol.29 , pp. 78-86
    • Bonomi, P.1
  • 15
    • 1242340431 scopus 로고    scopus 로고
    • Oncogenic Ras and its role in tumor cell invasion and metastasis
    • Campbell PM & Der CJ 2004 Oncogenic Ras and its role in tumor cell invasion and metastasis. Seminars in Cancer Biology 14 105-114.
    • (2004) Seminars in Cancer Biology , vol.14 , pp. 105-114
    • Campbell, P.M.1    Der, C.J.2
  • 16
    • 0036097190 scopus 로고    scopus 로고
    • Bradykinin antagonist dimer, CU201, inhibits the growth of human lung cancer cell lines in vitro and in vivo and produces synergistic growth inhibition in combination with other antitumor agents
    • Chan DC, Gera L, Stewart JM, Helfrich B, Zhao TL, Feng WY, Chan KK, Covey JM & Bunn PA Jr 2002 Bradykinin antagonist dimer, CU201, inhibits the growth of human lung cancer cell lines in vitro and in vivo and produces synergistic growth inhibition in combination with other antitumor agents. Clinical Cancer Research 8 1280-1287.
    • (2002) Clinical Cancer Research , vol.8 , pp. 1280-1287
    • Chan, D.C.1    Gera, L.2    Stewart, J.M.3    Helfrich, B.4    Zhao, T.L.5    Feng, W.Y.6    Chan, K.K.7    Covey, J.M.8    Bunn Jr, P.A.9
  • 17
    • 9244256817 scopus 로고    scopus 로고
    • Inhibition of akt/protein kinase B signaling by naltrindole in small cell lung cancer cells
    • Chen YL, Law PY & Loh HH 2004 Inhibition of akt/protein kinase B signaling by naltrindole in small cell lung cancer cells. Cancer Research 64 8723-8730.
    • (2004) Cancer Research , vol.64 , pp. 8723-8730
    • Chen, Y.L.1    Law, P.Y.2    Loh, H.H.3
  • 19
    • 0347504835 scopus 로고    scopus 로고
    • TRP channels as cellular sensors
    • Clapham DE 2003 TRP channels as cellular sensors. Nature 426 517-524.
    • (2003) Nature , vol.426 , pp. 517-524
    • Clapham, D.E.1
  • 20
    • 0031776001 scopus 로고    scopus 로고
    • Small-cell lung cancer: Treatment progress and prospects
    • discussion 661-643
    • Clark R & Ihde DC 1998 Small-cell lung cancer: treatment progress and prospects. Oncology (Williston Park) 12 647-658 (discussion 661-643).
    • (1998) Oncology (Williston Park) , vol.12 , pp. 647-658
    • Clark, R.1    Ihde, D.C.2
  • 21
    • 29544439599 scopus 로고    scopus 로고
    • Recent advances in Ca(2+)-dependent Ras regulation and cell proliferation
    • Cook SJ & Lockyer PJ 2006 Recent advances in Ca(2+)-dependent Ras regulation and cell proliferation. Cell Calcium 39 101-112.
    • (2006) Cell Calcium , vol.39 , pp. 101-112
    • Cook, S.J.1    Lockyer, P.J.2
  • 23
    • 17244378994 scopus 로고    scopus 로고
    • Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4 and annexin II
    • Derbyshire ZE, Halfter UM, Heimark RL, Sy TH & Vaillancourt RR 2005 Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4 and annexin II. Molecular and Cellular Biochemistry 271 77-90.
    • (2005) Molecular and Cellular Biochemistry , vol.271 , pp. 77-90
    • Derbyshire, Z.E.1    Halfter, U.M.2    Heimark, R.L.3    Sy, T.H.4    Vaillancourt, R.R.5
  • 24
    • 0029907265 scopus 로고    scopus 로고
    • A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
    • Dikic I, Tokiwa G, Lev S, Courtneidge SA & Schlessinger J 1996 A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature 383 547-550.
    • (1996) Nature , vol.383 , pp. 547-550
    • Dikic, I.1    Tokiwa, G.2    Lev, S.3    Courtneidge, S.A.4    Schlessinger, J.5
  • 27
    • 0032524389 scopus 로고    scopus 로고
    • RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs
    • Ebinu JO, Bottorff DA, Chan EY, Stang SL, Dunn RJ & Stone JC 1998 RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Science 280 1082-1086.
    • (1998) Science , vol.280 , pp. 1082-1086
    • Ebinu, J.O.1    Bottorff, D.A.2    Chan, E.Y.3    Stang, S.L.4    Dunn, R.J.5    Stone, J.C.6
  • 31
    • 0345304866 scopus 로고    scopus 로고
    • 2+-selective cation channel TRPV6 in human prostate cancer: A novel prognostic marker for tumor progression
    • 2+-selective cation channel TRPV6 in human prostate cancer: a novel prognostic marker for tumor progression. Oncogene 22 7858-7861.
    • (2003) Oncogene , vol.22 , pp. 7858-7861
    • Fixemer, T.1    Wissenbach, U.2    Flockerzi, V.3    Bonkhoff, H.4
  • 32
    • 0033552615 scopus 로고    scopus 로고
    • Induction of cell scattering by expression of β1 integrins in β1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function
    • Gimond C, van Der Flier A, van Delft S, Brakebusch C, Kuikman I, Collard JG, Fassler R & Sonnenberg A 1999 Induction of cell scattering by expression of β1 integrins in β1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function. Journal of Cell Biology 147 1325-1340.
    • (1999) Journal of Cell Biology , vol.147 , pp. 1325-1340
    • Gimond, C.1    van Der Flier, A.2    van Delft, S.3    Brakebusch, C.4    Kuikman, I.5    Collard, J.G.6    Fassler, R.7    Sonnenberg, A.8
  • 33
    • 0036080595 scopus 로고    scopus 로고
    • CaM kinase II-dependent activation of tyrosine kinases and ERK1/2 in vascular smooth muscle
    • Ginnan R & Singer HA 2002 CaM kinase II-dependent activation of tyrosine kinases and ERK1/2 in vascular smooth muscle. American Journal of Physiology. Cell Physiology 282 C754-C761.
    • (2002) American Journal of Physiology. Cell Physiology , vol.282
    • Ginnan, R.1    Singer, H.A.2
  • 34
    • 0035230048 scopus 로고    scopus 로고
    • Multiple pathways of ERK activation by G protein-coupled receptors
    • discussion 80-64, 150-159
    • Gudermann T 2001 Multiple pathways of ERK activation by G protein-coupled receptors. Novartis Foundation Symposium 239 68-79 (discussion 80-64, 150-159).
    • (2001) Novartis Foundation Symposium , vol.239 , pp. 68-79
    • Gudermann, T.1
  • 36
    • 19244365565 scopus 로고    scopus 로고
    • Gudermann T, Mederos y Schnitzler M & Dietrich A 2004 Receptor-operated cation entry - more than esoteric terminology? Science's STKE pe35.
    • Gudermann T, Mederos y Schnitzler M & Dietrich A 2004 Receptor-operated cation entry - more than esoteric terminology? Science's STKE pe35.
  • 37
    • 0031016389 scopus 로고    scopus 로고
    • Reduction in receptors for bombesin and epidermal growth factor in xenografts of human small-cell lung cancer after treatment with bombesin antagonist RC-3095
    • Halmos G & Schally AV 1997 Reduction in receptors for bombesin and epidermal growth factor in xenografts of human small-cell lung cancer after treatment with bombesin antagonist RC-3095. PNAS 94 956-960.
    • (1997) PNAS , vol.94 , pp. 956-960
    • Halmos, G.1    Schally, A.V.2
  • 38
    • 0037542854 scopus 로고    scopus 로고
    • Ras proteins: Different signals from different locations
    • Hancock JF 2003 Ras proteins: different signals from different locations. Nature Reviews Molecular Cell Biology 4 373-384.
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , pp. 373-384
    • Hancock, J.F.1
  • 40
    • 21744433347 scopus 로고    scopus 로고
    • CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells
    • Hartmann TN, Burger JA, Glodek A, Fujii N & Burger M 2005 CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells. Oncogene 24 4462-4471.
    • (2005) Oncogene , vol.24 , pp. 4462-4471
    • Hartmann, T.N.1    Burger, J.A.2    Glodek, A.3    Fujii, N.4    Burger, M.5
  • 41
    • 0032525199 scopus 로고    scopus 로고
    • The related adhesion focal tyrosine kinase (RAFTK) is tyrosine phosphorylated and participates in colony-stimulating factor-1/macrophage colony-stimulating factor signaling in monocyte-macrophages
    • Hatch WC, Ganju RK, Hiregowdara D, Avraham S & Groopman JE 1998 The related adhesion focal tyrosine kinase (RAFTK) is tyrosine phosphorylated and participates in colony-stimulating factor-1/macrophage colony-stimulating factor signaling in monocyte-macrophages. Blood 91 3967-3973.
    • (1998) Blood , vol.91 , pp. 3967-3973
    • Hatch, W.C.1    Ganju, R.K.2    Hiregowdara, D.3    Avraham, S.4    Groopman, J.E.5
  • 42
    • 0035952679 scopus 로고    scopus 로고
    • Autocrine and paracrine signaling through neuropeptide receptors in human cancer
    • Heasley LE 2001 Autocrine and paracrine signaling through neuropeptide receptors in human cancer. Oncogene 20 1563-1569.
    • (2001) Oncogene , vol.20 , pp. 1563-1569
    • Heasley, L.E.1
  • 44
    • 0033538342 scopus 로고    scopus 로고
    • i proteins use a novel βγ- and Ras-independent pathway to activate extracellular signal-regulated kinase and mobilize AP-1 transcription factors in Jurkat T lymphocytes
    • i proteins use a novel βγ- and Ras-independent pathway to activate extracellular signal-regulated kinase and mobilize AP-1 transcription factors in Jurkat T lymphocytes. Journal of Biological Chemistry 274 19992-20001.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 19992-20001
    • Hedin, K.E.1    Bell, M.P.2    Huntoon, C.J.3    Karnitz, L.M.4    McKean, D.J.5
  • 45
    • 0029955660 scopus 로고    scopus 로고
    • An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase
    • Hildebrand JD, Taylor JM & Parsons JT 1996 An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Molecular and Cellular Biology 16 3169-3178.
    • (1996) Molecular and Cellular Biology , vol.16 , pp. 3169-3178
    • Hildebrand, J.D.1    Taylor, J.M.2    Parsons, J.T.3
  • 48
    • 9644269056 scopus 로고    scopus 로고
    • Genotoxicity of environmental tobacco smoke: A review
    • Husgafvel-Pursiainen K 2004 Genotoxicity of environmental tobacco smoke: a review. Mutation Research 567 427-445.
    • (2004) Mutation Research , vol.567 , pp. 427-445
    • Husgafvel-Pursiainen, K.1
  • 49
    • 0033792527 scopus 로고    scopus 로고
    • Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium
    • Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R & Kitamura H 2000 Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development 127 3913-3921.
    • (2000) Development , vol.127 , pp. 3913-3921
    • Ito, T.1    Udaka, N.2    Yazawa, T.3    Okudela, K.4    Hayashi, H.5    Sudo, T.6    Guillemot, F.7    Kageyama, R.8    Kitamura, H.9
  • 51
    • 0036191304 scopus 로고    scopus 로고
    • Rho GTPases in transformation and metastasis
    • Jaffe AB & Hall A 2002 Rho GTPases in transformation and metastasis. Advances in Cancer Research 84 57-80.
    • (2002) Advances in Cancer Research , vol.84 , pp. 57-80
    • Jaffe, A.B.1    Hall, A.2
  • 54
    • 0028122890 scopus 로고
    • Tyrosine 508 of the 85 kilodalton subunit of phosphatidylinositol 3-kinase is phosphorylated by the platelet-derived growth factor receptor
    • Kavanaugh WM, Turck CW, Klippel A & Williams LT 1994 Tyrosine 508 of the 85 kilodalton subunit of phosphatidylinositol 3-kinase is phosphorylated by the platelet-derived growth factor receptor. Biochemistry 33 11046-11050.
    • (1994) Biochemistry , vol.33 , pp. 11046-11050
    • Kavanaugh, W.M.1    Turck, C.W.2    Klippel, A.3    Williams, L.T.4
  • 55
    • 0037381940 scopus 로고    scopus 로고
    • 2+ channels and phosphoinositide 3-kinase in endothelin-1-induced PYK2 tyrosine phosphorylation
    • 2+ channels and phosphoinositide 3-kinase in endothelin-1-induced PYK2 tyrosine phosphorylation. Molecular Pharmacology 63 808-813.
    • (2003) Molecular Pharmacology , vol.63 , pp. 808-813
    • Kawanabe, Y.1    Hashimoto, N.2    Masaki, T.3
  • 56
    • 4944267210 scopus 로고    scopus 로고
    • Growth factor independence-1 is expressed in primary human neuroendocrine lung carcinomas and mediates the differentiation of murine pulmonary neuroendocrine cells
    • Kazanjian A, Wallis D, Au N, Nigam R, Venken KJ, Cagle PT, Dickey BF, Bellen HJ, Gilks CB & Grimes HL 2004 Growth factor independence-1 is expressed in primary human neuroendocrine lung carcinomas and mediates the differentiation of murine pulmonary neuroendocrine cells. Cancer Research 64 6874-6882.
    • (2004) Cancer Research , vol.64 , pp. 6874-6882
    • Kazanjian, A.1    Wallis, D.2    Au, N.3    Nigam, R.4    Venken, K.J.5    Cagle, P.T.6    Dickey, B.F.7    Bellen, H.J.8    Gilks, C.B.9    Grimes, H.L.10
  • 57
    • 0032055396 scopus 로고    scopus 로고
    • SynGAP: A synaptic RasGAP that associates with the PSD-95/SAP90 protein family
    • Kim JH, Liao D, Lau LF & Huganir RL 1998 SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family. Neuron 20 683-691.
    • (1998) Neuron , vol.20 , pp. 683-691
    • Kim, J.H.1    Liao, D.2    Lau, L.F.3    Huganir, R.L.4
  • 59
    • 0042031108 scopus 로고    scopus 로고
    • The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1
    • Kruljac-Letunic A, Moelleken J, Kallin A, Wieland F & Blaukat A 2003 The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1. Journal of Biological Chemistry 278 29560-29570.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 29560-29570
    • Kruljac-Letunic, A.1    Moelleken, J.2    Kallin, A.3    Wieland, F.4    Blaukat, A.5
  • 60
    • 0036729867 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy
    • Krystal GW, Sulanke G & Litz J 2002 Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy. Molecular Cancer Therapeutics 1 913-922.
    • (2002) Molecular Cancer Therapeutics , vol.1 , pp. 913-922
    • Krystal, G.W.1    Sulanke, G.2    Litz, J.3
  • 63
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by β-arrestins
    • Lefkowitz RJ & Shenoy SK 2005 Transduction of receptor signals by β-arrestins. Science 308 512-517.
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 65
    • 0032981482 scopus 로고    scopus 로고
    • Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein
    • Lev S, Hernandez J, Martinez R, Chen A, Plowman G & Schlessinger J 1999 Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein. Molecular and Cellular Biology 19 2278-2288.
    • (1999) Molecular and Cellular Biology , vol.19 , pp. 2278-2288
    • Lev, S.1    Hernandez, J.2    Martinez, R.3    Chen, A.4    Plowman, G.5    Schlessinger, J.6
  • 67
    • 0034693049 scopus 로고    scopus 로고
    • Targeting of PYK2 to focal adhesions as a cellular mechanism for convergence between integrins and G protein-coupled receptor signaling cascades
    • Litvak V, Tian D, Shaul YD & Lev S 2000 Targeting of PYK2 to focal adhesions as a cellular mechanism for convergence between integrins and G protein-coupled receptor signaling cascades. Journal of Biological Chemistry 275 32736-32746.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 32736-32746
    • Litvak, V.1    Tian, D.2    Shaul, Y.D.3    Lev, S.4
  • 70
    • 0141988690 scopus 로고    scopus 로고
    • c-MET mutational analysis in small cell lung cancer: Novel juxtamembrane domain mutations regulating cytoskeletal functions
    • Ma PC, Kijima T, Maulik G, Fox EA, Sattler M, Griffin JD, Johnson BE & Salgia R 2003 c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions. Cancer Research 63 6272-6281.
    • (2003) Cancer Research , vol.63 , pp. 6272-6281
    • Ma, P.C.1    Kijima, T.2    Maulik, G.3    Fox, E.A.4    Sattler, M.5    Griffin, J.D.6    Johnson, B.E.7    Salgia, R.8
  • 73
    • 0033146386 scopus 로고    scopus 로고
    • Arg6,D-Trp7,9,NmePhe8]-substance P (6-11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism
    • MacKinnon AC, Armstrong RA, Waters CM, Cummings J, Smyth JF, Haslett C & Sethi T 1999 [Arg6,D-Trp7,9,NmePhe8]-substance P (6-11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism. British Journal of Cancer 80 1026-1034.
    • (1999) British Journal of Cancer , vol.80 , pp. 1026-1034
    • MacKinnon, A.C.1    Armstrong, R.A.2    Waters, C.M.3    Cummings, J.4    Smyth, J.F.5    Haslett, C.6    Sethi, T.7
  • 74
    • 0035958925 scopus 로고    scopus 로고
    • Bombesin and substance P analogues differentially regulate G-protein coupling to the bombesin receptor. Direct evidence for biased agonism
    • MacKinnon AC, Waters C, Jodrell D, Haslett C & Sethi T 2001 Bombesin and substance P analogues differentially regulate G-protein coupling to the bombesin receptor. Direct evidence for biased agonism. Journal of Biological Chemistry 276 28083-28091.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 28083-28091
    • MacKinnon, A.C.1    Waters, C.2    Jodrell, D.3    Haslett, C.4    Sethi, T.5
  • 75
    • 0033537356 scopus 로고    scopus 로고
    • Favourable prognosis in Lambert-Eaton myasthenic syndrome and small-cell lung carcinoma
    • Maddison P, Newsom-Davis J, Mills KR & Souhami RL 1999 Favourable prognosis in Lambert-Eaton myasthenic syndrome and small-cell lung carcinoma. Lancet 353 117-118.
    • (1999) Lancet , vol.353 , pp. 117-118
    • Maddison, P.1    Newsom-Davis, J.2    Mills, K.R.3    Souhami, R.L.4
  • 76
    • 0035398487 scopus 로고    scopus 로고
    • G-protein-coupled receptors and signaling networks: Emerging paradigms
    • Marinissen MJ & Gutkind JS 2001 G-protein-coupled receptors and signaling networks: emerging paradigms. Trends in Pharmacological Sciences 22 368-376.
    • (2001) Trends in Pharmacological Sciences , vol.22 , pp. 368-376
    • Marinissen, M.J.1    Gutkind, J.S.2
  • 77
    • 0032564460 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide inhibits human small-cell lung cancer proliferation in vitro and in vivo
    • Maruno K, Absood A & Said SI 1998 Vasoactive intestinal peptide inhibits human small-cell lung cancer proliferation in vitro and in vivo. PNAS 95 14373-14378.
    • (1998) PNAS , vol.95 , pp. 14373-14378
    • Maruno, K.1    Absood, A.2    Said, S.I.3
  • 79
    • 0141523025 scopus 로고    scopus 로고
    • Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model
    • Meuwissen R, Linn SC, Linnoila RI, Zevenhoven J, Mooi WJ & Berns A 2003 Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model. Cancer Cell 4 181-189.
    • (2003) Cancer Cell , vol.4 , pp. 181-189
    • Meuwissen, R.1    Linn, S.C.2    Linnoila, R.I.3    Zevenhoven, J.4    Mooi, W.J.5    Berns, A.6
  • 81
    • 33644875032 scopus 로고    scopus 로고
    • The TRP superfamily of cation channels
    • Montell C 2005 The TRP superfamily of cation channels. Science STKE re3.
    • (2005) Science STKE
    • Montell, C.1
  • 83
    • 0032534025 scopus 로고    scopus 로고
    • The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway
    • Moore SM, Rintoul RC, Walker TR, Chilvers ER, Haslett C & Sethi T 1998 The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway. Cancer Research 58 5239-5247.
    • (1998) Cancer Research , vol.58 , pp. 5239-5247
    • Moore, S.M.1    Rintoul, R.C.2    Walker, T.R.3    Chilvers, E.R.4    Haslett, C.5    Sethi, T.6
  • 84
    • 0032242416 scopus 로고    scopus 로고
    • Synthesis of peptide and pseudopeptide amides inhibiting the proliferation of small cell and epithelial types of lung carcinoma cells
    • Nyeki O, Rill A, Schon I, Orosz A, Schrett J, Bartha L & Nagy J 1998 Synthesis of peptide and pseudopeptide amides inhibiting the proliferation of small cell and epithelial types of lung carcinoma cells. Journal of Peptide Science 4 486-495.
    • (1998) Journal of Peptide Science , vol.4 , pp. 486-495
    • Nyeki, O.1    Rill, A.2    Schon, I.3    Orosz, A.4    Schrett, J.5    Bartha, L.6    Nagy, J.7
  • 86
    • 0028930676 scopus 로고
    • New short-chain analogs of a substance-P antagonist inhibit proliferation of human small-cell lung-cancer cells in vitro and in vivo
    • Orosz A, Schrett J, Nagy J, Bartha L, Schon I & Nyeki O 1995 New short-chain analogs of a substance-P antagonist inhibit proliferation of human small-cell lung-cancer cells in vitro and in vivo. International Journal of Cancer 60 82-87.
    • (1995) International Journal of Cancer , vol.60 , pp. 82-87
    • Orosz, A.1    Schrett, J.2    Nagy, J.3    Bartha, L.4    Schon, I.5    Nyeki, O.6
  • 87
    • 0033083095 scopus 로고    scopus 로고
    • Protein kinase D in small cell lung cancer cells: Rapid activation through protein kinase C
    • Paolucci L & Rozengurt E 1999 Protein kinase D in small cell lung cancer cells: rapid activation through protein kinase C. Cancer Research 59 572-577.
    • (1999) Cancer Research , vol.59 , pp. 572-577
    • Paolucci, L.1    Rozengurt, E.2
  • 91
  • 92
    • 26844456493 scopus 로고    scopus 로고
    • Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines
    • Plummer HK III, Dhar MS, Cekanova M & Schuller HM 2005 Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines. BMC Cancer 5 104.
    • (2005) BMC Cancer , vol.5 , pp. 104
    • Plummer III, H.K.1    Dhar, M.S.2    Cekanova, M.3    Schuller, H.M.4
  • 93
    • 0033958493 scopus 로고    scopus 로고
    • Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression
    • Prawitt D, Enklaar T, Klemm G, Gartner B, Spangenberg C, Winterpacht A, Higgins M, Pelletier J & Zabel B 2000 Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression. Human Molecular Genetics 9 203-216.
    • (2000) Human Molecular Genetics , vol.9 , pp. 203-216
    • Prawitt, D.1    Enklaar, T.2    Klemm, G.3    Gartner, B.4    Spangenberg, C.5    Winterpacht, A.6    Higgins, M.7    Pelletier, J.8    Zabel, B.9
  • 95
    • 0035809922 scopus 로고    scopus 로고
    • Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein
    • Ren XR, Du QS, Huang YZ, Ao SZ, Mei L & Xiong WC 2001 Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein. Journal of Cell Biology 152 971-984.
    • (2001) Journal of Cell Biology , vol.152 , pp. 971-984
    • Ren, X.R.1    Du, Q.S.2    Huang, Y.Z.3    Ao, S.Z.4    Mei, L.5    Xiong, W.C.6
  • 97
    • 0028277844 scopus 로고
    • Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras
    • Rosen LB, Ginty DD, Weber MJ & Greenberg ME 1994 Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron 12 1207-1221.
    • (1994) Neuron , vol.12 , pp. 1207-1221
    • Rosen, L.B.1    Ginty, D.D.2    Weber, M.J.3    Greenberg, M.E.4
  • 98
    • 0031741856 scopus 로고    scopus 로고
    • Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists
    • Rozengurt E 1998 Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists. Journal of Cellular Physiology 177 507-517.
    • (1998) Journal of Cellular Physiology , vol.177 , pp. 507-517
    • Rozengurt, E.1
  • 99
    • 0032995692 scopus 로고    scopus 로고
    • Autocrine loops, signal transduction, and cell cycle abnormalities in the molecular biology of lung cancer
    • Rozengurt E 1999 Autocrine loops, signal transduction, and cell cycle abnormalities in the molecular biology of lung cancer. Current Opinion in Oncology 11 116-122.
    • (1999) Current Opinion in Oncology , vol.11 , pp. 116-122
    • Rozengurt, E.1
  • 100
    • 0036551292 scopus 로고    scopus 로고
    • Neuropeptides as growth factors for normal and cancerous cells
    • Rozengurt E 2002 Neuropeptides as growth factors for normal and cancerous cells. Trends in Endocrinology and Metabolism 13 128-134.
    • (2002) Trends in Endocrinology and Metabolism , vol.13 , pp. 128-134
    • Rozengurt, E.1
  • 101
    • 0035131504 scopus 로고    scopus 로고
    • TRP-PLIK, a bifunctional protein with kinase and ion channel activities
    • Runnels LW, Yue L & Clapham DE 2001 TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science 291 1043-1047.
    • (2001) Science , vol.291 , pp. 1043-1047
    • Runnels, L.W.1    Yue, L.2    Clapham, D.E.3
  • 103
    • 0035952766 scopus 로고    scopus 로고
    • Heterotrimeric G-protein betagamma-dimers in growth and differentiation
    • Schwindinger WF & Robishaw JD 2001 Heterotrimeric G-protein betagamma-dimers in growth and differentiation. Oncogene 20 1653-1660.
    • (2001) Oncogene , vol.20 , pp. 1653-1660
    • Schwindinger, W.F.1    Robishaw, J.D.2
  • 104
    • 0030614842 scopus 로고    scopus 로고
    • Seckl MJ, Higgins T, Widmer F & Rozengurt E 1997 [D-Arg1, D-Trp5,7,9,Leu11]substance P: a novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells. Cancer Research 57 51-54.
    • Seckl MJ, Higgins T, Widmer F & Rozengurt E 1997 [D-Arg1, D-Trp5,7,9,Leu11]substance P: a novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells. Cancer Research 57 51-54.
  • 105
    • 0026681259 scopus 로고
    • Growth of small cell lung cancer cells: Stimulation by multiple neuropeptides and inhibition by broad spectrum antagonists in vitro and in vivo
    • s
    • Sethi T, Langdon S, Smyth J & Rozengurt E 1992 Growth of small cell lung cancer cells: stimulation by multiple neuropeptides and inhibition by broad spectrum antagonists in vitro and in vivo. Cancer Research 52 2737s-2742s.
    • (1992) Cancer Research , vol.52
    • Sethi, T.1    Langdon, S.2    Smyth, J.3    Rozengurt, E.4
  • 108
    • 13144302858 scopus 로고    scopus 로고
    • Agonist-induced down-regulation of type 1 and type 3 inositol 1,4,5-trisphosphate receptors in A7r5 and DDT1 MF-2 smooth muscle cells
    • Sipma H, Deelman L, Smedt HD, Missiaen L, Parys JB, Vanlingen S, Henning RH & Casteels R 1998 Agonist-induced down-regulation of type 1 and type 3 inositol 1,4,5-trisphosphate receptors in A7r5 and DDT1 MF-2 smooth muscle cells. Cell Calcium 23 11-21.
    • (1998) Cell Calcium , vol.23 , pp. 11-21
    • Sipma, H.1    Deelman, L.2    Smedt, H.D.3    Missiaen, L.4    Parys, J.B.5    Vanlingen, S.6    Henning, R.H.7    Casteels, R.8
  • 110
    • 0036260904 scopus 로고    scopus 로고
    • The immunopathogenesis of paraneoplastic neurological syndromes
    • Sutton I & Winer JB 2002 The immunopathogenesis of paraneoplastic neurological syndromes. Clinical Science (London) 102 475-486.
    • (2002) Clinical Science (London) , vol.102 , pp. 475-486
    • Sutton, I.1    Winer, J.B.2
  • 112
  • 114
    • 0030904698 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated adhesion by the small GTP-binding protein Rho in small cell lung carcinoma cells
    • Tokman MG, Porter RA & Williams CL 1997 Regulation of cadherin-mediated adhesion by the small GTP-binding protein Rho in small cell lung carcinoma cells. Cancer Research 57 1785-1793.
    • (1997) Cancer Research , vol.57 , pp. 1785-1793
    • Tokman, M.G.1    Porter, R.A.2    Williams, C.L.3
  • 115
  • 116
    • 0035328671 scopus 로고    scopus 로고
    • Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins
    • Tsavaler L, Shapero MH, Morkowski S & Laus R 2001 Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. Cancer Research 61 3760-3769.
    • (2001) Cancer Research , vol.61 , pp. 3760-3769
    • Tsavaler, L.1    Shapero, M.H.2    Morkowski, S.3    Laus, R.4
  • 118
    • 24944522719 scopus 로고    scopus 로고
    • Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy
    • Tsurutani J, West KA, Sayyah J, Gills JJ & Dennis PA 2005 Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy. Cancer Research 65 8423-8432.
    • (2005) Cancer Research , vol.65 , pp. 8423-8432
    • Tsurutani, J.1    West, K.A.2    Sayyah, J.3    Gills, J.J.4    Dennis, P.A.5
  • 119
    • 0034678330 scopus 로고    scopus 로고
    • Suppression of Pyk2 kinase and cellular activities by FIP200
    • Ueda H, Abbi S, Zheng C & Guan JL 2000 Suppression of Pyk2 kinase and cellular activities by FIP200. Journal of Cell Biology 149 423-430.
    • (2000) Journal of Cell Biology , vol.149 , pp. 423-430
    • Ueda, H.1    Abbi, S.2    Zheng, C.3    Guan, J.L.4
  • 120
    • 0642348940 scopus 로고    scopus 로고
    • The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies
    • Varker KA, Phelps SH, King MM & Williams CL 2003 The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies. International Journal of Oncology 22 671-681.
    • (2003) International Journal of Oncology , vol.22 , pp. 671-681
    • Varker, K.A.1    Phelps, S.H.2    King, M.M.3    Williams, C.L.4
  • 123
  • 126
    • 0034910622 scopus 로고    scopus 로고
    • Molecular genetics of small cell lung carcinoma
    • Wistuba II, Gazdar AF & Minna JD 2001 Molecular genetics of small cell lung carcinoma. Seminars in Oncology 28 3-13.
    • (2001) Seminars in Oncology , vol.28 , pp. 3-13
    • Wistuba II, G.A.F.1    Minna, J.D.2
  • 127
    • 0034738958 scopus 로고    scopus 로고
    • The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins
    • Wittau N, Grosse R, Kalkbrenner F, Gohla A, Schultz G & Gudermann T 2000 The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins. Oncogene 19 4199-4209.
    • (2000) Oncogene , vol.19 , pp. 4199-4209
    • Wittau, N.1    Grosse, R.2    Kalkbrenner, F.3    Gohla, A.4    Schultz, G.5    Gudermann, T.6
  • 128
    • 0028363961 scopus 로고
    • Muscarinic receptor activation downregulates the type I inositol 1,4,5-trisphosphate receptor by accelerating its degradation
    • Wojcikiewicz RJ, Furuichi T, Nakade S, Mikoshiba K & Nahorski SR 1994 Muscarinic receptor activation downregulates the type I inositol 1,4,5-trisphosphate receptor by accelerating its degradation. Journal of Biological Chemistry 269 7963-7969.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 7963-7969
    • Wojcikiewicz, R.J.1    Furuichi, T.2    Nakade, S.3    Mikoshiba, K.4    Nahorski, S.R.5
  • 131
    • 0030777767 scopus 로고    scopus 로고
    • Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase
    • Xiong W & Parsons JT 1997 Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase. Journal of Cell Biology 139 529-539.
    • (1997) Journal of Cell Biology , vol.139 , pp. 529-539
    • Xiong, W.1    Parsons, J.T.2
  • 132
    • 0031846188 scopus 로고    scopus 로고
    • Expression and characterization of splice variants of PYK2, a focal adhesion kinase-related protein
    • Xiong WC, Macklem M & Parsons JT 1998 Expression and characterization of splice variants of PYK2, a focal adhesion kinase-related protein. Journal of Cell Science 111 (Pt 14) 1981-1991.
    • (1998) Journal of Cell Science , vol.111 , Issue.PART 14 , pp. 1981-1991
    • Xiong, W.C.1    Macklem, M.2    Parsons, J.T.3
  • 133
    • 33646016274 scopus 로고    scopus 로고
    • TRPM8 in prostate cancer cells: A potential diagnostic and prognostic marker with a secretory function?
    • Zhang L & Barritt GJ 2006 TRPM8 in prostate cancer cells: a potential diagnostic and prognostic marker with a secretory function? Endocrine-Related Cancer 13 27-38.
    • (2006) Endocrine-Related Cancer , vol.13 , pp. 27-38
    • Zhang, L.1    Barritt, G.J.2
  • 134
    • 0030770603 scopus 로고    scopus 로고
    • Critical role of calcium-dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling
    • Zwick E, Daub H, Aoki N, Yamaguchi-Aoki Y, Tinhofer I, Maly K & Ullrich A 1997 Critical role of calcium-dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling. Journal of Biological Chemistry 272 24767-24770.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 24767-24770
    • Zwick, E.1    Daub, H.2    Aoki, N.3    Yamaguchi-Aoki, Y.4    Tinhofer, I.5    Maly, K.6    Ullrich, A.7


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