Multiple pathways of ERK activation by G protein-coupled receptors

Novartis Foundation Symposium

Volumn 239, Issue , 2001, Pages 68-79

  Gudermann, Thomas ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CELL SURFACE RECEPTOR; CYCLIC AMP; G PROTEIN BETA GAMMA; G-PROTEIN BETA GAMMA; GNAI2 PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; OLFACTORY G PROTEIN SUBUNIT ALPHA OLF; ONCOPROTEIN; PROTEIN TYROSINE KINASE; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

CYTOSKELETON; ENZYME ACTIVATION; HUMAN; METABOLISM; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION;

CALCIUM; CYCLIC AMP; CYTOSKELETON; ENZYME ACTIVATION; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; GTP-BINDING PROTEINS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; LIGANDS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, CELL SURFACE;

EID: 0035230048     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (35)

1. Bos JL 1998 All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral. EMBO J 17:6776-6782
2. Boudreau NJ, Jones PL 1999 Extracellular matrix and integrin signalling: the shape of things to come. Biochem J 339:481-488
3. de Rooij J, Zwartkruis FJ, Verheijen MH et al 1998 Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature 396:474-477
4. DeFea KA, Zalevsky J, Thoma MS, Déry O, Mullins RD, Bunnett NW 2000 β-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J Cell Biol 148:1267-1281
5. Fan H, Derynck R 1999 Ectodomain shedding of TGF-α and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades. EMBO J 18:6962-6972
6. Farfel Z, Bourne HR, Iiri T 1999 The expanding spectrum of G protein diseases. N Engl J Med 340:1012-1020
7. Gechtman Z, Alonso JL, Raab G, Ingber DE, Klagsbrun M 1999 The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading. J Biol Chem 274:28828-28835
8. Gross S, Knebel A, Tenev T et al 1999 Inactivation of protein-tyrosine phosphatases as mechanisms of UV-induced signal transduction. J Biol Chem 274:26378-26386
9. Grosse R, Roelle S, Herrlich A, Höhn J, Gudermann T 2000a Epidermal growth factor receptor tyrosine kinase mediates Ras activation by gonadotropin releasing hormone. J Biol Chem 275:12251-12260
10. q/11 proteins. J Biol Chem 275:9193-9200
11. Gudermann T, Kalkbrenner F, Schultz G 1996 Diversity and selectivity of receptor-G protein interaction. Annu Rev Pharmacol Toxicol 36:429-459
12. Gudermann T, Grosse R, Schultz G 2000 Contribution of receptor/G protein signaling to cell growth and transformation. Naunyn Schmiedebergs Arch Pharmacol 361:345-362
13. Gutkind JS 1998 Cell growth control by G protein-coupled receptors: from signal transduction to signal integration. Oncogene 17:1331-1342
14. Heeneman S, Haendler J, Saito Y, Ishida M, Berk BC 2000 Angiotensin II induces transactivation of two different populations of the PDGFβ-receptor: Key role for the adaptor protein Shc. J Biol Chem 275:15926-15932
15. Herrlich A, Daub H, Knebel A et al 1998 Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic acid-stimulated mitogenic activity in L cells. Proc Natl Acad Sci USA 95:8985-8990
16. o with Rap1 GTPase-activating protein. J Biol Chem 274:21507-21510
17. Kawasaki H, Springett GM, Mochizuki N et al 1998 A family of cAMP-binding proteins that directly activate Rap1. Science 282:2275-2279
18. src. J Biol Chem 275:12619-12625
19. Mm following phosphorylation by the nonreceptor tyrosine kinase Src. J Biol Chem 275:5441-5446
20. Kranenburg O, Verlaan I, Moolenaar WH 1999 Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase. J Biol Chem 274:35301-35304
21. Luttrell LM, Daaka Y, Lefkowitz RJ 1999 Regulation of tyrosine kinase cascades by G-protein-coupled receptors. Curr Opin Cell Biol 11:177-183
22. Marais R, Light Y, Mason C, Paterson H, Olson MF, Marshall CJ 1998 Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C. Science 280: 109-112
23. 2-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. J Biol Chem 275:9572-9580
24. z and Rap1GAP suggests a novel form of cellular cross-talk. J Biol Chem 274:36663-36669
25. Miller WE, Maudsley S, Ahn S, Khan KD, Luttrell LM, Lefkowitz RJ 2000 β-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of β-arrestin1-dependent targeting of c-SRC in receptor endocytosis. J Biol Chem 275:11312-11319
26. i. Nature 400:891-894
27. Pierce KL, Maudsley S, Daaka Y, Luttrell LM, Lefkowitz RJ 2000 Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors. Proc Natl Acad Sci USA 97:1489-1494
28. Prenzel N, Zwick E, Daub H et al 1999 EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402: 884-888
29. Saxena M, Williams S, Taskén K, Mustellin T 1999 Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase. Nat Cell Biol 1:305-311
30. Schlaepfer DD, Hauck CR, Sieg DJ 1999 Signaling through focal adhesion kinase. Prog Biophys Mol Biol 71:435-478
31. Wilde A, Beattie EC, Lem L et al 1999 EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. Cell 96:677-687
32. Yamashita S, Mochizuki N, Ohba Y et al 2000 CalDAG-GEFIII activation of Ras, R-Ras, and Rap1. J Biol Chem 275:25488-25493
33. Zrihan-Licht S, Fu Y, Settleman J et al 2000 RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion. Oncogene 19:1318-1328
34. Zwick E, Hackel PO, Prenzel N, Ullrich A 1999a The EGF receptor as central transducer of heterologous signalling systems. Trends Pharmacol Sci 20:408-412
35. Zwick E, Wallasch C, Daub H, Ullrich A 1999b Distinct calcium-dependent pathways of epidermal growth factor receptor transactivation and PYK2 tyrosine phosphorylation in PC12 cells. J Biol Chem 274:20989-20996