Recent advances in Ca2+-dependent Ras regulation and cell proliferation

Cell Calcium

Volumn 39, Issue 2, 2006, Pages 101-112

  Cook, Simon J ^a   Lockyer, Peter J ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

Calcium; Cancer; Cell cycle; Cell proliferation; GAP; GEF; GTPase; Rap; Ras

Indexed keywords

CALCIUM BINDING PROTEIN; CALCIUM ION; CALMODULIN; CALPHOBINDIN II; CYCLIN DEPENDENT KINASE; GUANOSINE TRIPHOSPHATASE; RAS PROTEIN;

CALCIUM BINDING; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REVIEW;

EID: 29544439599     PISSN: 01434160     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ceca.2005.10.014     Document Type: Short Survey

References (83)

1. M.G. Lee P. Nurse Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2 Nature 327 1987 31-35
2. S. Ortega M. Malumbres M. Barbacid Cyclin D-dependent kinases, INK4 inhibitors and cancer Biochim. Biophys. Acta 1602 2002 73-87
3. C.X. Deng P.M. Zhang J.W. Harper S.J. Elledge P. Leder Mice lacking P21(C/P1/Waf1) undergo normal development, but are defective in G1 checkpoint control Cell 82 1995 675-684
4. J.W. Harper S.J. Elledge K. Keyomarsi B. Dynlacht L.H. Tsai P.M. Zhang S. Dobrowolski C. Bai L. Connell-Crowley E. Swindell M.P. Fox N. Wei Inhibition of cyclin-dependent kinases by P21 Mol. Biol. Cell 6 1995 387-400
5. D.E. Quelle F. Zindy R.A. Ashmun C.J. Sherr Alternative reading frames of the Ink4a tumor-suppressor gene encode 2 unrelated proteins capable of inducing cell-cycle arrest Cell 83 1995 993-1000
6. D.E. Quelle R.A. Ashmun G.J. Hannon P.A. Rehberger D. Trono K.H. Richter C. Walker D. Beach C.J. Sherr M. Serrano Cloning and characterization of murine P16(Ink4a) and P15(Ink4b) genes Oncogene 11 1995 635-645
7. J. Lukas J. Bartkova J. Bartek Convergence of mitogenic signaling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G(1) checkpoint Mol. Cell. Biol. 16 1996 6917-6925
8. M. Hall G. Peters Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer Adv. Cancer Res. 68 1996 67-108
9. F. McCormick Going for the GAP Curr. Biol. 8 1998 R673-R674
10. J.L. Bos Ras oncogenes in human cancer-a review Cancer Res. 49 1989 4682-4689
11. J.F. Hancock Ras proteins: Different signals from different locations Nat. Rev. Mol. Cell Biol. 4 2003 373-384
12. S.A. Walker P.J. Lockyer Visualizing Ras signalling in real-time J. Cell Sci. 117 2004 2879-2886
13. P.J. Cullen P.J. Lockyer Integration of calcium and Ras signalling Nat. Rev. Mol. Cell Biol. 3 2002 339-348
14. 2+ FEBS Lett. 546 2003 6-10
15. M.L. Coleman C.J. Marshall M.F. Olson Ras and Rho GTPases in G1-phase cell-cycle regulation Nat. Rev. Mol. Cell Biol. 5 2004 355-366
16. S. Mittnacht H. Paterson M.F. Olson C.J. Marshall Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein Curr. Biol. 7 1997 219-221
17. J.J. Liu J.R. Chao M.C. Jiang S.Y. Ng J.J.Y. Yen H.F. Yangyen Ras transformation results in an elevated level of cyclin D1 and acceleration of G(1) progression in NIH 3T3 cells Mol. Cell. Biol. 15 1995 3654-3663
18. H. Gille J. Downward Multiple Ras effector pathways contribute to G1 cell cycle progression J. Biol. Chem. 274 1999 22033-22040
19. C. Albanese J. Johnson G. Watanabe N. Eklund D. Vu A. Arnold R.G. Pestell Transforming P21(Ras) mutants and C-Ets-2 activate the cyclin D1 promoter through distinguishable regions J. Biol. Chem. 270 1995 23589-23597
20. G.M. D'Abaco S. Hooper H. Paterson C.J. Marshall Loss of Rb overrides the requirement for ERK activity for cell proliferation J. Cell Sci. 115 2002 4607-4616
21. J.A. Diehl M. Cheng M.F. Roussel C.J. Sherr Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization Genes Dev. 12 1998 3499-3511
22. C.R. Kahl A.R. Means Regulation of cell cycle progression by calcium/ calmodulin-dependent pathways Endocr. Rev. 24 2003 719-736
23. 2+-dependent stimulation of retinoblastoma gene-product phosphorylation and p34cdc2 kinase activation in serum-stimulated human fibroblasts J. Biol. Chem. 268 1993 138-145
24. S.D. Balk J.F. Whitfield T. Youdale A.C. Braun Roles of calcium, serum, plasma, and folic acid in the control of proliferation of normal and Rous Sarcoma virus-infected chicken fibroblasts Proc. Natl. Acad. Sci. U.S.A. 70 1973 675-679
25. S.H. Swierenga J.F. Whitfield S. Karasaki Loss of proliferative calcium dependence: Simple in vitro indicator of tumorigenicity Proc. Natl. Acad. Sci. U.S.A. 75 1978 6069-6072
26. A.L. Boynton J.F. Whitfield Different calcium requirements for proliferation of conditionally and unconditionally tumorigenic mouse cells Proc. Natl. Acad. Sci. U.S.A. 73 1976 1651-1654
27. B.E. Weissman S.A. Aaronson Balb and Kirsten murine sarcoma-viruses alter growth and differentiation of Egf-dependent Balb/C mouse epidermal keratinocyte lines Cell 32 1983 599-606
28. B. Weissman S.A. Aaronson Members of the Src and Ras oncogene families supplant the epidermal growth-factor requirement of Balb/Mk-2 keratinocytes and induce distinct alterations in their terminal differentiation program Mol. Cell. Biol. 5 1985 3386-3396
29. F. Lang F. Friedrich E. Kahn E. Woll M. Hammerer S. Waldegger K. Maly H. Grunicke Bradykinin-induced oscillations of cell membrane potential in cells expressing the Ha-ras oncogene J. Biol. Chem. 266 1991 4938-4942
30. 2+ influx in voltage-clamped Ras-transformed NIH/3T3 fibroblasts J. Biol. Chem. 268 1993 19403-19410
31. N. Berry K. Ase A. Kishimoto Y. Nishizuka Activation of resting human T cells requires prolonged stimulation of protein kinase C Proc. Natl. Acad. Sci. U.S.A. 87 1990 2294-2298
32. N.A. Dower S.L. Stang D.A. Bottorff J.O. Ebinu P. Dickie H.L. Ostergaard J.C. Stone RasGRP is essential for mouse thymocyte differentiation and TCR signaling Nat. Immunol. 1 2002 317-321
33. J.P. Roose M. Mollenauer V.A. Gupta J. Stone A. Weiss A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells Mol. Cell. Biol. 25 2005 4426-4441
34. E.D. Emberley L.C. Murphy P.H. Watson S100 proteins and their influence on pro-survival pathways in cancer Biochem. Cell Biol. 82 2004 508-515
35. I. Marenholz C.W. Heizmann G. Fritz S100 proteins in mouse and man: From evolution to function and pathology (including an update of the nomenclature) Biochem. Biophys. Res. Commun. 322 2004 1111-1122
36. J. Lin M. Blake C. Tang D. Zimmer R.R. Rustandi D.J. Weber F. Carrier Inhibition of p53 transcriptional activity by the S100B calcium-binding protein J. Biol. Chem. 276 2001 35037-35041
37. R.R. Rustandi D.M. Baldisseri D.J. Weber Structure of the negative regulatory domain of p53 bound to S100B Nat. Struct. Mol. Biol. 7 2000 570-574
38. A. Mueller B.W. Schafer S. Ferrari M. Weibel M. Makek M. Hochli C.W. Heizmann The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity J. Biol. Chem. 280 2005 29186-29193
39. M.J. Hayes S.E. Moss Annexins and disease Biochem. Biophys. Res. Commun. 322 2004 1166-1170
40. M. Srivastava C. Montagna X. Leighton M. Glasman S. Naga O. Eidelman T. Ried H.B. Pollard Haploinsufficiency of Anx7 tumor suppressor gene and consequent genomic instability promotes tumorigenesis in the Anx7(±) mouse Proc. Natl. Acad. Sci. U.S.A. 100 2003 14287-14292
41. 2+ pump J. Biol. Chem. 276 2001 26737-26740
42. 2+ ATPase type 2 downregulated in human oral squamous cell carcinoma Int. J. Cancer 110 2004 225-231
43. K. Cichowski T. Jacks NF1 tumor suppressor gene function: Narrowing the GAP Cell 104 2001 593-604
44. T. Jacks T.S. Shih E.M. Schmitt R.T. Bronson A. Bernards R.A. Weinberg Tumor predisposition in mice heterozygous for a targeted mutation in Nf1 Nat. Genet. 7 1994 353-361
45. R.M. Costa N.B. Federov J.H. Kogan G.G. Murphy J. Stern M. Ohno R. Kucherlapati T. Jacks A.J. Silva Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1 Nature 415 2002 526-530
46. D.N. Cooper M. Upadhyaya Neurofibromatosis Type 1: From Genotype to Phenotype 1998 Bios Scientific Oxford
47. T. Korkiamaki H. Yla-Outinen J. Koivunen S.L. Karvonen J. Peltonen Altered calcium-mediated cell signaling in keratinocytes cultured from patients with neurofibromatosis type 1 Am. J. Pathol. 160 2002 1981-1990
48. E. Friedman P.V. Gejman G.A. Martin F. McCormick Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours Nat. Genet. 5 1993 242-247
49. L.M. Boon J.B. Mulliken M. Vikkula RASA1: Variable phenotype with capillary and arteriovenous malformations Curr. Opin. Genet. Dev. 15 2005 265-269
50. T. Grewal F. Tebar A. Pol C. Enrich Annexin A6 and its role in Ras signaling Annexins 1 2004 62-67
51. E. Smythe P.D. Smith S.M. Jacob J. Theobald S.E. Moss Endocytosis occurs independently of annexin VI in human A431 cells J. Cell Biol. 124 1994 301-306
52. J. Theobald A. Hanby K. Patel S.E. Moss Annexin VI has tumor-suppressor activity in human A431 squamous epithelial carcinoma-cells Br. J. Cancer 71 1995 786-788
53. 2+-dependent phospholipid-binding (CalB) domain within P120 gap, a GTPase-activating protein for P21 Ras Biochem. J. 307 1995 487-491
54. D.J. Gawler L.J. Zhang M. Reedijk P.S. Tung M.F. Moran CalB-a 43 amino-acid calcium-dependent membrane phospholipid-binding domain in P120 Ras GTPase-activating protein Oncogene 10 1995 817-825
55. 2+-dependent membrane-binding proteins. Evidence for a direct interaction between annexin VI and P120GAP J. Biol. Chem. 271 1996 24333-24336
56. T. Grewal R. Evans C. Rentero F. Tebar L. Cubells I.D. Diego M.F. Kirchhoff W.E. Hughes J. Heeren K.A. Rye F. Rinninger R.J. Daly A. Pol C. Enrich Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity Oncogene 24 2005 5809-5820
57. T.E. Hawkins J. Roes D. Rees J. Monkhouse S.E. Moss Immunological development and cardiovascular function are normal in annexin VI null mutant mice Mol. Cell. Biol. 19 1999 8028-8032
58. 2+ stores, phosphorylation of eIF2alpha, and sustained inhibition of translation initiation mediate the anticancer effects of clotrimazole Proc. Natl. Acad. Sci. U.S.A. 95 1998 8280-8285
59. A.M. Patton J. Kassis H. Doong E.C. Kohn Calcium as a molecular target in angiogenesis Curr. Pharm. Des. 9 2003 543-551
60. 2+ -dependent inactivation of the Ras-MAPK pathway Curr. Biol. 11 2001 981-986
61. 2+ oscillations EMBO J. 23 2004 1749-1760
62. 2+ J. Cell Biol. 170 2005 183-190
63. C.P. Kratz B.M. Emerling S. Donovan M. Laig-Webster B.R. Taylor P. Thompson S. Jensen A. Banerjee J. Bonifas W. Makalowski E.D. Green M.M. Le Beau K.M. Shannon Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies Genomics 77 2001 171-180
64. K.M. Shannon J. Watterson P. Johnson P. O'Connell B. Lange N. Shah P. Steinherz Y.W. Kan J.R. Priest Monosomy 7 myeloproliferative disease in children with neurofibromatosis, type 1: Epidemiology and molecular analysis Blood 79 1992 1311-1318
65. T.F. Westbrook E.S. Martin M.R. Schlabach Y. Leng A.C. Liang B. Feng J.J. Zhao T.M. Roberts G. Mandel G.J. Hannon R.A. DePinho L. Chin S.J. Elledge A genetic screen for candidate tumor suppressors identifies REST Cell 121 2005 837-848
66. I.G. Kolfschoten B. van Leeuwen K. Berns J. Mullenders R.L. Beijersbergen R. Bernards P.M. Voorhoeve R. Agami A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity Cell 121 2005 849-858
67. J. Zhang J. Guo I. Dzhagalov Y.-W. He An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis Nat. Immun. 6 2005 911-919
68. S. Greenberg A CAPRIciously translocating Rac adaptor Nat. Immun. 6 2005 864-866
69. 2+/calmodulin J. Cell Biol. 170 2005 429-441
70. L.B. Rosen D.D. Ginty M.J. Weber M.E. Greenberg Membrane depolarization and calcium influx stimulate Mek and Map kinase via activation of Ras Neuron 12 1994 1207-1221
71. C.J. Marshall Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation Cell 80 1995 179-185
72. CIP1 Mol. Cell Biol. 17 1997 5598-5611
73. CIP1 and a subset of AP-1 proteins in CCL39 cells Oncogene 18 1999 3085-3097
74. 2+, and calmodulin Cell. Signal. 14 2002 649-654
75. 2+ -dependent signal pathways in Rat-1 cells J. Biol. Chem. 272 1997 13309-13319
76. M. Bosch J. Gil O. Bachs N. Agell Calmodulin inhibitor W13 induces sustained activation of ERK2 and expression of p21(cip1) J. Biol. Chem. 273 1998 22145-22150
77. P. Villalonga C. Lopez-Alcala A. Chiloeches J. Gil R. Marais O. Bachs N. Agell Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts J. Biol. Chem. 277 2002 37929-37935
78. G.G. Kelley S.E. Reks J.M. Ondrako A.V. Smrcka Phospholipase C epsilon: a novel Ras effector EMBO J. 20 2001 743-754
79. I. Lopez E.C. Mak J.R. Ding H.E. Hamm J.W. Lomasney A novel bifunctional phospholipase C that is regulated by G alpha(12) and stimulates the Ras/ mitogen-activated protein kinase pathway J. Biol. Chem. 276 2001 2758-2765
80. C. Song C.D. Hu M. Masago K. Kariya Y. Yamawaki-Kataoka M. Shibatohge D.M. Wu T. Satoh T. Kataoka Regulation of a novel human phospholipase C, PLC epsilon, through membrane targeting by Ras J. Biol. Chem. 276 2001 2752-2757
81. A. Schulze K. Lehmann H.B.J. Jefferies M. McMahon J. Downward Analysis of the transcriptional program induced by Raf in epithelial cells Genes Dev. 15 2001 981-994
82. J. Schultz F. Milpetz P. Bork C.P. Ponting SMART, a simple modular architecture research tool: Identification of signaling domains Proc. Natl. Acad. Sci. 95 1998 5857-5864
83. M. Berridge Calcium signalling and cell proliferation Bioessays 17 1995 491-500