Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4 and annexin II

Molecular and Cellular Biochemistry

Volumn 271, Issue 1-2, 2005, Pages 77-90

  Derbyshire, Zachary E ^a   Halfter, Ursula M ^a   Heimark, Ronald L ^a   Sy, Terence H ^a   Vaillancourt, Richard R ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Angiotensin II; Annexin II; Cyclooxygenase II; Insect cells; MEKK4; p38 MAP kinase; Pyk2

Indexed keywords

ANGIOTENSIN; CYCLOOXYGENASE 2; FOCAL ADHESION KINASE 2; LIPOCORTIN 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; RECOMBINANT PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FAR WESTERN BLOTTING; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MASS SPECTROMETRY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SMOOTH MUSCLE FIBER; TRANSCRIPTION REGULATION; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN II; ANIMALS; ANNEXIN A2; CALCIUM; CELLS, CULTURED; CYCLOOXYGENASE 2; FOCAL ADHESION KINASE 2; HUMANS; MAP KINASE KINASE 6; MAP KINASE KINASE KINASE 4; MEMBRANE PROTEINS; MUSCLE, SMOOTH, VASCULAR; ONCOGENE PROTEIN PP60(V-SRC); PHOSPHORYLATION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN-TYROSINE KINASES; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TYROSINE;

INSECTA;

EID: 17244378994     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11010-005-5386-9     Document Type: Article

References (42)

1. Lange-Carter CA, Pleiman CM, Gardner AM, Blumer KJ, Johnson GL: A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science260: 315-319, 1993
2. Gerwins P, Blank JL, Johnson GL: Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway. J Biol Chem 272: 8288-8295, 1997
3. Mita H, Tsutsui J, Takekawa M, Witten EA, Saito H: Regulation of MTK1/ MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding. Mol Cell Biol 22: 4544-4555, 2002
4. Takekawa M, Saito H: A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK. Cell 95: 521-530, 1998
5. Takekawa M, Posas F, Saito, H: A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways. EMBO J 16: 4973-4982, 1997
6. Murasawa S, Matsubara H, Mori Y, Masaki H, Tsutsumi Y, Shibasaki Y, Kitabayashi I, Tanaka Y, Fujiyama S, Koyama Y, Fujiyama A, Iba S, Iwasaka T: Angiotensin II initiates tyrosine kinase Pyk2-dependent signalings leading to activation of Rac1-mediated c-Jun NH2-terminal kinase. J Biol Chem 275: 26856-26863, 2000
7. Eguchi S, Iwasaki H, Inagami T, Numaguchi K, Yamakawa T, Motley ED, Owada KM, Marumo F, Hirata Y: Involvement of PYK2 in angiotensin II signaling of vascular smooth muscle cells. Hypertension 33: 201-206, 1999
8. Haendeler J, Berk BC: Angiotensin II mediated signal transduction. Important role of tyrosine kinases. Regul Pept 95: 1-7, 2000
9. Rocic P, Govindarajan G, Sabri A, Lucchesi PA: A role for PYK2 in regulation of ERK1/2 MAP kinases and PI 3-kinase by ANG II in vascular smooth muscle. Am J Physiol Cell Physiol 280: C90-C99, 2001
10. Pandey P, Avraham S, Kumar S, Nakazawa A, Place A, Ghanem L, Rana A, Kumar V, Majumder PK, Avraham H, Davis RJ, Kharbanda S: Activation of p38 mitogen-activated protein kinase by PYK2/related adhesion focal tyrosine kinase-dependent mechanism. J Biol Chem 274: 10140-10144, 1999
11. Sorokin A, Kozlowski P, Graves L, Philip A: Protein-tyrosine kinase Pyk2 mediates endothelin-induced p38 MAPK activation in glomerular mesangial cells. J Biol Chem 276: 21521-21528, 2001
12. Rebsamen MC, Capoccia R, Vallotton MB, Lang U: Role of cyclooxygenase 2, p38 and p42/44 MAPK in the secretion of prostacyclin induced by epidermal growth factor, endothelin-1 and angiotensin II in rat ventricular cardiomyocytes. J Mol Cell Cardiol 35: 81-89, 2003
13. Wang Z, Brecher P: Salicylate inhibits phosphorylation of the nonreceptor tyrosine kinases, proline-rich tyrosine kinase 2 and c-Src. Hypertension 37: 148-153, 2001
14. Robeva AS, Woodard R, Luthin DR, Taylor HE, Linden J: Double tagging recombinant A1- and A2A-adenosine receptors with hexahistidine and the FLAG epitope. Development of an efficient generic protein purification procedure. Biochem Pharmacol 51: 545-555, 1996
15. Sarkar G, Sommer SS: The "megaprimer" method of site-directed mutagenesis. Biotechniques 8: 404-407, 1990
16. techniques to study kinase anchoring. Methods Mol Biol 88: 47-64, 1998
17. Shevchenko A, Wilm M, Vorm O, Mann M: Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68: 850-858, 1996 10.1021/ac950914h
18. Sabri A, Govindarajan G, Griffin TM, Byron KL, Samarel AM, Lucchesi PA: Calcium- and protein kinase C-dependent activation of the tyrosine kinase PYK2 by angiotensin II in vascular smooth muscle. Circ Res 83: 841-851, 1998
19. Johnsson N, Marriott G, Weber K: P36, the major cytoplasmic substrate of src tyrosine protein kinase, binds to its p11 regulatory subunit via a short amino-terminal amphiphatic helix. EMBO J 7: 2435-2442, 1988
20. 2+ and phospholipid. FEBS Lett 192: 79-82, 1985
21. Mallon R, Feldberg LR, Kim SC, Collins K, Wojciechowicz D, Hollander I, Kovacs ED, Kohler C: An enzyme-linked immunosorbent assay for the Raf/ MEK1/MAPK signaling cascade. Anal Biochem 294: 48-54, 2001
22. Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J: A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature383: 547-550, 1996
23. Zanke BW, Rubie EA, Winnett E, Chan J, Randall S, Parsons M, Boudreau K, McInnis M, Yan M, Templeton DJ, Woodgett JR: Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes. J Biol Chem 271: 29876-29881, 1996
24. Wei C, Cardarelli MG, Downing SW, McLaughlin JS: The effect of angiotensin II on mitogen-activated protein kinase in human cardiomyocytes. J Renin Angiotensin Aldosterone Syst 1: 379-384, 2000
25. Ohnaka K, Numaguchi K, Yamakawa T, Inagami T: Induction of cyclooxygenase-2 by angiotensin II in cultured rat vascular smooth muscle cells. Hypertension 35: 68-75, 2000
26. Inoue H, Yokoyama C, Hara S, Tone Y, Tanabe T: Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element. J Biol Chem 270: 24965-24971, 1995
27. Hagemann C, Blank JL: The ups and downs of MEK kinase interactions. Cell Signal 13: 863-875, 2001
28. Garrington TP, Johnson GL: Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr Opin Cell Biol 11: 211-218, 1999
29. Widmann C, Gibson S, Jarpe MB, Johnson GL: Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human. Physiol Rev 79: 143-180, 1999 1:CAS:528:DyaK1MXhs1Cgu7s%3D
30. Fanger GR, Widmann C, Porter AC, Sather S, Johnson GL, Vaillancourt RR: 14-3-3 proteins interact with specific MEK kinases. J Biol Chem 273: 3476-3483, 1998
31. Guan Z, Buckman SY, Pentland AP, Templeton DJ, Morrison AR: Induction of cyclooxygenase-2 by the activated MEKK1 → SEK1/MKK4 → p38 mitogen-activated protein kinase pathway. J Biol Chem 273: 12901-12908, 1998
32. Scheuren N, Jacobs M, Ertl G, Schorb W: Cyclooxygenase-2 in myocardium stimulation by angiotensin-II in cultured cardiac fibroblasts and role at acute myocardial infarction. J Mol Cell Cardiol 34: 29-37, 2002
33. Berk BC, Corson MA: Angiotensin II signal transduction in vascular smooth muscle: Role of tyrosine kinases. Circ Res 80: 607-616, 1997
34. Eguchi S, Numaguchi K, Iwasaki H, Matsumoto T, Yamakawa T, Utsunomiya H, Motley ED, Kawakatsu H, Owada KM, Hirata Y, Marumo F, Inagami T: Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. J Biol Chem 273: 8890-8896, 1998
35. Lakkakorpi PT, Bett AJ, Lipfert L, Rodan GA, Duong le T: PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption. J Biol Chem 278: 11502-11512, 2003
36. Salgia R, Avraham S, Pisick E, Li JL, Raja S, Greenfield EA, Sattler M, Avraham H, Griffin JD: The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells. J Biol Chem 271: 31222-31226, 1996
37. Yu H, Li X, Marchetto GS, Dy R, Hunter D, Calvo B, Dawson TL, Wilm M, Anderegg RJ, Graves LM, Earp HS: Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation. J Biol Chem 271: 29993-29998, 1996
38. Jost M, Thiel C, Weber K, Gerke V: Mapping of three unique Ca(2+)-binding sites in human annexin II. Eur J Biochem 207: 923-930, 1992
39. Brinson AE, Harding T, Diliberto PA, He Y, Li X, Hunter D, Herman B, Earp HS, Graves LM: Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton. J Biol Chem 273: 1711-1718, 1998
40. Hubaishy I, Jones PG, Bjorge J, Bellagamba C, Fitzpatrick S, Fujita DJ, Waisman DM: Modulation of annexin II tetramer by tyrosine phosphorylation. Biochemistry 34: 14527-14534, 1995
41. Kintscher U, Wakino S, Kim S, Fleck E, Hsueh WA, Law RE: Angiotensin II induces migration and Pyk2/paxillin phosphorylation of human monocytes. Hypertension 37: 587-593, 2001
42. Pai R, Szabo IL, Giap AQ, Kawanaka H, Tarnawski AS: Nonsteroidal anti-inflammatory drugs inhibit re-epithelialization of wounded gastric monolayers by interfering with actin, Src, FAK, and tensin signaling. Life Sci69: 3055-3071, 2001