ANG II and LPA induce Pyk2 tyrosine phosphorylation in intestinal epithelial cells: Role of Ca2+, PKC, and Rho kinase

American Journal of Physiology - Cell Physiology

Volumn 282, Issue 6 51-6, 2002, Pages

  Wu, Steven S ^a   Chiu, Terence ^b   Rozengurt, Enrique ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cytochalasin D; G protein coupled receptor; Gi; Gq; IEC 18; Migration; Paxillin

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ANGIOTENSIN; BACTERIAL ENZYME; CALCIUM ION; CYTOCHALASIN D; FASUDIL; IONOMYCIN; LYSOPHOSPHATIDIC ACID; PAXILLIN; PHORBOL DIBUTYRATE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; RHO KINASE;

ANIMAL CELL; ARTICLE; CLOSTRIDIUM BOTULINUM; CONTROLLED STUDY; ENZYME ACTIVITY; INTESTINE EPITHELIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALIA; BACTERIA (MICROORGANISMS); CLOSTRIDIUM; CLOSTRIDIUM BOTULINUM;

EID: 0036087255     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00323.2001     Document Type: Article

References (66)

1. Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase
2. Protein kinases C-gamma and -delta are involved in insulin-like growth factor I-induced migration of colonic epithelial cells
3. RAFTK/Pyk2-mediated cellular signaling
4. Angiotensin II induces contraction and proliferation of human hepatic stellate cells
5. Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades
6. Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton
7. Differentiation of rat small intestinal epithelial cells by extracellular matrix
8. PKD in intestinal epithelial cells: Rapid activation by phorbol esters, LPA, and angiotensin through PKC
9. Vasopressin-mediated mitogenic signaling in intestinal epithelial cells
10. Transforming growth factor beta regulation of migration in wounded rat intestinal epithelial monolayers
11. Specificity and mechanism of action of some commonly used protein kinase inhibitors
12. Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase
13. p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction
14. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
15. Tyrosine kinase and MAPK inhibition of TNF-α- and EGF-stimulated IEC-6 cell growth
16. Involvement of PYK2 in angiotensin II signaling of vascular smooth muscle cells
17. Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor
18. Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF
19. RAFTK a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytes
20. Angiotensin receptors and their antagonists
21. Glycogen synthase kinase 3 beta is tyrosine phosphorylated by PYK2
22. Tyrosine phosphorylation of the related adhesion focal tyrosine kinase in megakaryocytes upon stem cell factor and phorbol myristate acetate stimulation and its association with paxillin
23. Identification of in vivo phosphorylation sites required for protein kinase D activation
24. Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases
25. src
26. 2+-induced regulation of ion channel and MAP kinase functions
27. Interactions between two cytoskeleton-associated tyrosine kinases: Calcium-dependent tyrosine kinase and focal adhesion tyrosine kinase
28. Paxillin is tyrosine-phosphorylated by and preferentially associates with the calcium-dependent tyrosine kinase in rat liver epithelial cells
29. Angiotensin II stimulates ERK via two pathways in epithelial cells: Protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway
30. Targeting of PYK2 to focal adhesions as a cellular mechanism for convergence between integrins and G protein-coupled receptor signaling cascades
31. Biological functions of angiotensin and its receptors
32. μ
33. Migration of IEC-6 cells: A model for mucosal healing
34. Lysophosphatidic acid, a multifunctional phospholipid messenger
35. Lysophosphatidic acid: G-protein signaling and cellular responses
36. 2-terminal kinase
37. Role of calcium-sensitive tyrosine kinase Pyk2/CAKβ/RAFTK in angiotensin II-induced Ras/ERK signaling
38. Rho kinase inhibitor HA-1077 prevents Rho-mediated myosin phosphatase inhibition in smooth muscle cells
39. Epidermal growth factor receptor-stimulated intestinal epithelial cell migration requires phospholipase C activity
40. Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria
41. 2+-RhoA signaling pathway required for polyamine-dependent intestinal epithelial cell migration
42. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
43. A role for PYK2 in regulation of ERK1/2 MAP kinases and PI 3-kinase by ANG II in vascular smooth muscle
44. Rho and ROCK modulate the tyrosine kinase PYK2 in T cells through regulation of the activity of the integrin LFA-1
45. The role of Rho in G protein-coupled receptor signal transduction
46. The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells
47. Rho proteins play a critical role in cell migration during the early phase of mucosal restitution
48. Autoradiographic characterization of angiotensin II receptor subtypes in rat intestine
49. PYK2 links Gqα and G13α signaling to NF-κB activation
50. G13α-mediated PYK2 activation
51. Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: Dissociation from tyrosine phosphorylation of p130cas
52. 2+ mobilization, and the actin cytoskeleton
53. Activation of AT-1 angiotensin receptors induces DNA synthesis in a rat intestinal epithelial (RIE-1) cell line
54. Identification of atypical (non-AT1, non-AT2) angiotensin binding sites with high affinity for angiotensin I on IEC-18 rat intestinal epithelial cells
55. Modulation of intestinal epithelial wound healing in vitro and in vivo by lysophosphatidic acid
56. The Hedgehog and Wnt signaling pathways in cancer
57. Regulation of calcium-sensitive tyrosine kinase Pyk2 by angiotensin II in endothelial cells. Roles of Yes tyrosine kinase and tyrosine phosphatase SHP-2
58. Cholecystokinin activates PYK2/CAKβ by a phospholipase C-dependent mechanism and its association with the mitogen-activated protein kinase signaling pathway in pancreatic acinar cells
59. Activation of Pyk2 by stress signals and coupling with JNK signaling pathway
60. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C
61. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
62. Temporal dispersion of activation of phospholipase C-β1 and -γ isoforms by angiotensin II in vascular smooth muscle cells. Role of αq/11, α12, and βγ G protein subunits
63. Nitric oxide inhibits angiotensin II-induced activation of the calcium-sensitive tyrosine kinase proline-rich tyrosine kinase 2 without affecting epidermal growth factor receptor transactivation
64. Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cells
65. q
66. Distinct calcium-dependent pathways of epidermal growth factor receptor transactivation and PYK2 tyrosine phosphorylation in PC12 cells