Protective activities of Vaccinium antioxidants with potential relevance to mitochondrial dysfunction and neurotoxicity

NeuroToxicology

Volumn 28, Issue 1, 2007, Pages 93-100

  Yao, Yu ^a   Vieira, Amandio ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Anthocyanins; Cytochrome c; Dopamine; Mitochondria; Neurotoxic; Vaccinium

Indexed keywords

ANTHOCYANIN; ASCORBIC ACID; CYANIDIN 3 GLUCOSIDE; CYTOCHROME C; FLAVONOID; MYRICETIN; OXIDOPAMINE; QUERCETIN;

AEROBIC METABOLISM; ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CORRELATION ANALYSIS; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG ACTIVITY; DRUG POTENCY; DRUG PURIFICATION; GLYCOSYLATION; METABOLITE; NEUROTOXICITY; PHYSIOLOGY; PRIORITY JOURNAL; VACCINIUM; VACCINIUM CORYMBOSUM; VACCINIUM MYRTILLUS; VACCINIUM OXYCOCCUS;

ANIMALS; ANTHOCYANINS; ANTIOXIDANTS; ASCORBIC ACID; CYTOCHROMES C; DOPAMINE; FLAVONOIDS; GLUCOSIDES; KINETICS; MITOCHONDRIA; NERVE DEGENERATION; NEUROTOXICITY SYNDROMES; OXIDATION-REDUCTION; OXIDOPAMINE; SYMPATHOLYTICS; VACCINIUM;

VACCINIUM; VACCINIUM CORYMBOSUM; VACCINIUM MYRTILLUS; VACCINIUM OXYCOCCUS;

EID: 33846808961     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2006.07.015     Document Type: Article

References (75)

1. Adams Jr. J.D., and Odunze I.N. Oxygen free radicals and Parkinson's disease. Free Radic Biol Med 10 (1991) 161-169
2. Ames B.N. Delaying the mitochondrial decay of aging. Ann NY Acad Sci 1019 (2004) 406-411
3. Ames B.M., Shigena M.K., and Hagen T.M. Oxidants, antioxidants and the degenerative diseases of aging. Proc Natl Acad Sci USA 90 (1993) 7915-7922
4. Arts I.C.W., van de Putte B., and Hollman P.C.H. Catechin contents of foods commonly consumed in the Netherlands. J Agric Food Chem 48 (2000) 1746-1751
5. Benzie I.F. Evolution of dietary antioxidants. Comp Biochem Physiol 136 (2003) 113-126
6. Berman S.B., and Hastings T.G. Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease. J Neurochem 73 (1999) 1127-1137
7. Bickford P.C., Gould T., Briederick L., Chadman K., Pollock A., Young D., Shukitt-Hale B., and Joseph J. Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats. Brain Res 866 (2000) 211-217
8. Bilyk A., and Sapers G.M. Varietal differences in the quercetin, kaempferol, and myricetin contents of highbush blueberry. J Agric Food Chem 34 (1986) 585-588
9. Bitsch I., Janssen M., Netzel M., Strass G., and Frank T. Bioavailability of anthocyanidin-3-glycosides following consumption of elderberry extract and blackcurrant juice. Int J Clin Pharmacol Ther 42 (2004) 293-300
10. Bormann H., and Melzig M.F. Inhibition of metallopeptidases by flavonoids and related compounds. Pharmazie 55 (2000) 129-132
11. Cai J., Yang J., and Jones D.P. Mitochondrial control of apoptosis: the role of cytochrome c. Biochim Biophys Acta 1366 (1998) 139-149
12. Chen Q., Takeyama N., Brady G., Watson A.J., and Dive C. Blood cells with reduced mitochondrial membrane potential and cytosolic cytochrome c can survive and maintain clonogenicity given appropriate signals to suppress apoptosis. Blood 92 (1998) 4545-4553
13. Clayton R., Clark J.B., and Sharpe M. Cytochrome c release from rat brain mitochondria is proportional to the mitochondrial functional deficit: implications for apoptosis and neurodegenerative disease. J Neurochem 92 (2005) 840-849
14. Cohen G., and Heikkila R.E. The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents. J Biol Chem 249 (1974) 2447-2452
15. De Iuliis A., Burlina A.P., Boschetto R., Zambenedetti P., Arslan P., and Galzigna L. Increased dopamine peroxidation in postmortem Parkinsonian brain. Biochim Biophys Acta 1573 (2002) 63-67
16. Deshmukh M., and Johnson J. Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c. Neuron 21 (1998) 695-705
17. Dessolin J., Schuler M., Quinart A., De Giorgi F., Ghosez L., and Ichas F. Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases?. Eur J Pharmacol 447 (2002) 155-161
18. Galli R.L., Shukitt-Hale B., Youdim K.A., and Joseph J.A. Fruit polyphenolics and brain aging: nutritional interventions targeting age-related neuronal and behavioural deficits. Ann NY Acad Sci 959 (2002) 128-132
19. Galli R.L., Bielinski D.F., Szprengiel A., Shukitt-Hale B., and Joseph J.A. Blueberry supplemented diet reverses age-related decline in hippocampal HSP70 neuroprotection. Neurobiol Aging 27 (2006) 344-350
20. Gao L., and Mazza G. Quantitation and distribution of simple and acylated anthocyanins and other phenolics in blueberries. J Food Sci 59 (1994) 1057-1059
21. Hakkinen S.H., Karenlampi S.O., Heinonen I.M., Mykkanen H.M., and Torronen A.R. Content of the flavonols quercetin, myricetin, and kaempferol in 25 edible berries. J Agric Food Chem 47 (1999) 2274-2279
22. Hashimoto M., Rockenstein E., Crews L., and Masliah E. Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer's and Parkinson's diseases. Neuromol Med 4 (2003) 21-36
23. Hashimoto M., Takeda A., Hsu L.J., Takenouchi T., and Masliah E. Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease. J Biol Chem 274 (1999) 28849-28852
24. Heinonen I.M., Lehtonen P.J., and Hopia A.I. Antioxidant activity of berry and fruit wines and liquors. J Agric Food Chem 46 (1998) 25-31
25. Hukkanen A.T., Polonen S.S., Karenlampi S.O., and Kokko H.I. Antioxidant capacity and phenolic content of sweet rowanberries. J Agric Food Chem 54 (2006) 112-119
26. Jenner P. Oxidative stress in Parkinson's disease and other neurodegenerative disorders. Pathol Biol 44 (1996) 57-64
27. Jones D.C., Gunasekar P.G., Borowitz J.L., and Isom G.E. Dopamine-induced apoptosis is mediated by oxidative stress and is enhanced by cyanide in differentiated PC12 cells. J Neurochem 74 (2000) 2296-2304
28. Joseph J.A., Shukitt-Hale B., and Casadesus G. Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds. Am J Clin Nutr 81 (2005) 313S-316S
29. Joseph J.A., Shukitt-Hale B., Denisova N.A., Bielinski D., Martin A., McEwen J.J., and Bickford P.C. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J Neurosci 19 (1999) 8114-8121
30. Justesen U., Knuthsen P., and Leth T. Quantitative analysis of flavonols, flavones, and flavanones in fruits, vegetables and beverages by high-performance liquid chromatography with photo-diode array and mass spectrometric detection. J Chromatogr A 799 (1998) 101-110
31. Kahkonen M.P., and Heinonen M. Antioxidant activity of anthocyanins and their aglycones. J Agric Food Chem 51 (2003) 628-633
32. Kahkonen M.P., Hopia A.I., and Heinonen M. Berry phenolics and their antioxidant activity. J Agric Food Chem 49 (2001) 4076-4082
33. Kalt W., Ryan D.A., Duy J.C., Prior R.L., Ehlenfeldt M.K., and Vander Kloet S.P. Interspecific variation in anthocyanins, phenolics, and antioxidant capacity among genotypes of highbush and lowbush blueberries (Vaccinium section cyanococcus spp.). J Agric Food Chem 49 (2001) 4761-4767
34. Kessler M., Ubeaud G., and Jung L. Anti- and pro-oxidant activity of rutin and quercetin derivatives. J Pharm Pharmacol 55 (2003) 131-142
35. Laughton M.J., Halliwell B., Evans P.J., and Hoult J.R. Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin. Effects on lipid peroxidation, hydroxyl radical generation and bleomycin-dependent damage to DNA. Biochem Pharmacol 38 (1989) 2859-2865
36. Lees D.H., and Francis F.J. Effect of gamma radiation on anthocyanin and flavonol pigments in cranberries. J Am Soc Hortic Sci 97 (1972) 128-132
37. Levites Y., Youdim M.B., Maor G., and Mandel S. Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures. Biochem Pharmacol 63 (2002) 21-29
38. Lohachoompol V., Srzednicki G., and Craske J. The change of total anthocyanins in blueberries and their antioxidant effect after drying and freezing. J Biomed Biotechnol 5 (2004) 248-252
39. Luo Y., Umegaki H., Wang X., Abe R., and Roth G.S. Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway. J Biol Chem 273 (1998) 3756-3764
40. Maatta-Riihinen K.R., Kamal-Eldin A., Mattila P.H., Gonzalez-Paramas A.M., and Torronen A.R. Distribution and contents of phenolic compounds in eighteen Scandinavian berry species. J Agric Food Chem 52 (2004) 4477-4486
41. Martinez C., Yanez J., Vicente V., Alcaraz M., Benavente-Garcia O., Castillo J., Lorente J., and Lozano J.A. Effects of several polyhydroxylated flavonoids on the growth of B16F10 melanoma and Melan-a melanocyte cell lines: influence of the sequential oxidation state of the flavonoid skeleton. Melanoma Res 13 (2003) 3-9
42. Martinou I., Desagher S., Eskes R., Antonsson B., Andre E., Fakan S., and Martinou J.C. The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event. J. Cell Biol 144 (1999) 883-889
43. Mazza G., Kay C.D., Cottrell T., and Holub B.J. Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J Agric Food Chem 50 (2002) 850-857
44. Mazzio E.A., Reams R.R., and Soliman K.F. The role of oxidative stress, impaired glycolysis and mitochondrial respiratory redox failure in the cytotoxic effects of 6-hydroxydopamine in vitro. Brain Res 1004 (2004) 29-44
45. Medina S., Martinez M., and Hernanz A. Antioxidants inhibit the human cortical neuron apoptosis induced by hydrogen peroxide, tumor necrosis factor alpha, dopamine and beta-amyloid peptide 1-42. Free Radic Res 36 (2002) 1179-1184
46. Metodiewa D., Jaiswal A.K., Cenas N., Dickancaite E., and Segura-Aguilar J. Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product. Free Radic Biol Med 26 (1999) 107-116
47. Meunier S., Hanedanian M., Desage-El Murr M., Nowaczyk S., Le Gall T., Pin S., Renault J.P., Boquet D., Creminon C., Mioskowski C., and Taran F. High-throughput evaluation of antioxidant and pro-oxidant activities of polyphenols with thymidine protection assays. Chembiochem 6 (2005) 1234-1241
48. Migliaccio E., Giorgio M., Mele S., Pelicci G., Reboldi P., Pandolfi P.P., Lanfrancone L., and Pelicci P.G. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402 (1999) 309-313
49. Moyer R.A., Hummer K.E., Finn C.E., Frei B., and Wrolstad R.E. Anthocyanins, phenolics, and antioxidant capacity in diverse small fruits: vaccinium, rubus, and ribes. J Agric Food Chem 50 (2002) 519-525
50. Nyman N.A., and Kumpulainen J.T. Determination of anthocyanidins in berries and red wine by high-performance liquid chromatography. J Agric Food Chem 49 (2001) 4183-4187
51. Oliver L., Lecabellec M.T., Pradal G., Meflah K., Kroemer G., and Vallette F.M. Constitutive presence of cytochrome c in the cytosol of a chemoresistant leukemic cell line. Apoptosis 10 (2005) 277-287
52. Prior R.L., Lazarus S.A., Cao G., Muccitelli H., and Hammerstone J.F. Identification of procyanidins and anthocyanins in blueberries and cranberries (Vaccinium spp.) using high-performance liquid chromatography/mass spectrometry. J Agric Food Chem 49 (2001) 1270-1276
53. Prior R.L., Cao G., Martin A., Sofic E., McEwen J., O'Brien C., Lischner N., Ehlenfeldt M., Kalt W., Krewer G., and Mainland C.M. Antioxidant capacity as influenced by total phenolic and anthocyanin content, maturity, and variety of Vaccinium species. J Agric Food Chem 46 (1998) 2686-2693
54. Rice-Evans C.A., Miller N.J., and Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med. 20 (1996) 933-956
55. Roig R., Cascon E., Arola L., Blade C., and Salvado M.J. Procyanidins protect Fao cells against hydrogen peroxide-induced oxidative stress. Biochim Biophys Acta 1572 (2002) 25-30
56. Sapers G.G., Jones S.B., and Maher G.T. Factors affecting the recovery of juice and anthocyanin from cranberries. J Amer Soc Hort Sci 108 (1983) 246-249
57. Sellappan S., Akoh C.C., and Krewer G. Phenolic compounds and antioxidant capacity of georgia-grown blueberries and blackberries. J Agric Food Chem 50 (2002) 2432-2438
58. Socci D.J., Crandall B.M., and Arendash G.W. Chronic antioxidant treatment improves the cognitive performance of aged rats. Brain Res 693 (1995) 88-94
59. Starke H., and Herrmann K. The phenolics of fruits. VIII. Changes in flavonol concentrations during fruit development. Z Lebensm Unters Forsch 161 (1976) 131-135
60. Talavéra S., Felgines C., Texier O., Besson C., Manach C., Lamaison J.L., and Rémésy C. Anthocyanins are efficiently absorbed from the small intestine in rats. J Nutr 134 (2004) 2275-2279
61. Taruscio T.G., Barney D.L., and Exon J. Content and profile of flavanoid and phenolic acid compounds in conjunction with the antioxidant capacity for a variety of northwest Vaccinium berries. J Agric Food Chem 52 (2004) 3169-3176
62. Tsuda T., Horio F., and Osawa T. Absorption and metabolism of cyanidin-3o-beta-d-glucoside in rats. FEBS Lett 449 (1999) 179-182
63. Uda Y., Price K.R., Williamson G., and Rhodes M.J. Induction of the anticarcinogenic marker enzyme, quinone reductase, in murine hepatoma cells in vitro by flavonoids. Cancer Lett 120 (1997) 213-216
64. Von Ahsen O., Waterhouse N.J., Kuwana T., Newmeyer D.D., and Green D.R. The 'harmless' release of cytochrome c. Cell Death Differ 7 (2000) 1192-1199
65. Wang H., Cao G., and Prior R.L. Oxygen radical absorbing capacity of anthocyanins. J Agric Food Chem 45 (1997) 304-309
66. Williams C.A., and Grayer R.J. Anthocyanins and other flavonoids. Nat Prod Rep 21 (2004) 539-573
67. Woodgate A., MacGibbon G., Walton M., and Dragunow M. The toxicity of 6-hydroxydopamine on PC12 and P19 cells. Brain Res Mol Brain Res 69 (1999) 84-92
68. Wu X., Cao G., and Prior R.L. Absorption and metabolism of anthocyanins in human subjects following consumption of elderberry or blueberry. J Nutr 132 (2002) 1865-1871
69. Wu X., Pittman III H.E., and Prior R.L. Pelargonidin is absorbed and metabolized differently than cyanidin after marionberry consumption in pigs. J Nutr 134 (2004) 2603-2610
70. Yao Y., Zhou S., Davison A., and Vieira A. A cytochrome c-enhanced peroxidation reaction with potential use in screening dietary antioxidants. J Pharm Biomed Anal 34 (2004) 1057-1061
71. Yoshino M., Haneda M., Naruse M., and Murakami K. Prooxidant activity of flavonoids: copper-dependent strand breaks and the formation of 8-hydroxy-2′-deoxyguanosine in DNA. Mol Genet Metab 68 (1999) 468-472
72. Zhang Z., Kou X., Fugal K., and McLaughlin J. Comparison of HPLC methods for determination of anthocyanins and anthocyanidins in bilberry extracts. J Agric Food Chem 52 (2004) 688-691
73. Zheng W., and Wang S.Y. Oxygen radical absorbing capacity of phenolics in blueberries, cranberries, chokeberries, and lingonberries. J Agric Food Chem 51 (2003) 502-509
74. Zheng Y., Wang C.Y., Wang S.Y., and Zheng W. Effect of high-oxygen atmospheres on blueberry phenolics, anthocyanins, and antioxidant capacity. J Agric Food Chem 51 (2003) 7162-7169
75. Zhou Y., and Singh B.R. Effect of light on anthocyanin levels in submerged. Harvested cranberry fruit. J Biomed Biotechnol 2004 (2004) 259-263