Content of the flavonols quercetin, myricetin, and kaempferol in 25 edible berries

Journal of Agricultural and Food Chemistry

Volumn 47, Issue 6, 1999, Pages 2274-2279

  Häkkinen, Sari H ^a   Kärenlampi, Sirpa O ^a   Heinonen, I Marina ^b   Mykkänen, Hannu M ^a   Törronen, A Riitta ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Berry; Flavonoid; Flavonol; Fruit; HPLC; Kaempferol; Myricetin; Quercetin

Indexed keywords

DRUG DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOL; KAEMPFEROL; KEMPFEROL; MYRICETIN; QUERCETIN;

ARTICLE; CHEMICAL ANALYSIS; CHEMISTRY; FRUIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SPECIES DIFFERENCE;

FLAVONOIDS; FRUIT; KAEMPFEROLS; QUERCETIN; SPECIES SPECIFICITY; SPECTROMETRY, MASS, SECONDARY ION;

ALLIUM CEPA; BRASSICA OLERACEA VAR. ACEPHALA; BRASSICA OLERACEA VAR. BOTRYTIS; EMPETRUM; GROSSULARIACEAE; PHOTINIA; RHAMNACEAE; RIBES HUDSONIANUM; SORBUS AUCUPARIA; VACCINIUM; VACCINIUM MACROCARPON; VACCINIUM MYRTILLUS; VACCINIUM VITIS-IDAEA;

EID: 0037842831     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf9811065     Document Type: Article

References (29)

1. Amiot, M. J.; Tacchini, M.; Aubert, S. Y.; Oleszek; W. Influence of cultivar, maturity stage, and storage conditions on phenolic composition and enzymatic browning of pear fruits. J. Agric. Food Chem. 1995, 43, 1132-1137.
2. Bilyk, A.; Sapers, G. M. Varietal differences in the quercetin, kaempferol, and myricetin contents of highbush blueberry, cranberry, and thornless blackberry fruits. J. Agric. Food Chem. 1986, 34, 585-588.
3. Bilyk, A.; Cooper, P. L.; Sapers, G. M. Varietal differences in distribution of quercetin and kaempferol in onion (Allium cepa L.) tissue. J. Agric. Food Chem. 1984, 32, 274-276.
4. Britton, G. The Biochemistry of Natural Pigments; Cambridge University Press: Cambridge, U.K., 1983.
5. Dixon, R. A.; Paiva, N. L. Stress-induced phenylpropanoid metabolism. Plant Cell 1995, 7, 1085-1097.
6. Häkkinen, S.; Auriola, S. High-performance liquid chromatography with electrospray ionization mass spectrometry and diode array ultraviolet detection in the identification of flavonol aglycones and glycosides in berries. J. Chromatogr. A 1998, 829, 91-100.
7. Häkkinen, S.; Mykkänen, H.; Kärenlampi, S.; Törrönen, R. Phenolic profiles in Finnish berries. In COST 916 Bioactive Plant Cell Wall Components in Nutrition and Health: Polyphenols in Food; Armadò, R., Andersson, H., Bardócz, S., Serra, F., Eds.; European Communities: Luxembourg, 1998a; pp 57-59.
8. Häkkinen, S. H.; Kärenlampi, S. O.; Heinonen, I. M.; Mykkänen, H. M.; Törrönen, A. R. HPLC method for screening of flavonoids and phenolic acids in berries. J. Sci. Food Agric. 1998b, 77, 543-551.
9. Heinonen, I. M.; Meyer, A. S.; Frankel, E. N. Antioxidant activity of berry phenolics on human low-density lipoprotein and liposome oxidation. J. Agric. Food Chem. 1998, 46, 4107-4112.
10. Hertog, M. G. L.; Katan, M. B. Quercetin in foods, cardiovascular disease, and cancer. In Flavonoids in Health and Disease; Rice-Evans, C. A., Packer, L., Eds.; Dekker: New York, 1998; pp 447-467.
11. Hertog, M. G. L.; Hollman, P. C. H.; Venema, D. P. Optimization of a quantitative HPLC determination of potentially anticarcinogenic flavonoids in vegetables and fruits. J. Agric. Food Chem. 1992a, 40, 1591-1598.
12. Hertog, M. G. L.; Hollman, P. C. H.; Katan, M. B. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in The Netherlands. J. Agric. Food Chem. 1992b, 40, 2379-2383.
13. Hertog, M. G. L.; Feskens, E. J. M.; Hollman, P. C. H.; Katan, M. B.; Kromhout, D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen elderly study. Lancet 1993a, 342, 1007-1011.
14. Hertog, M. G. L.; Hollman, P. C. H.; van de Putte, B. Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit juices. J. Agric. Food Chem. 1993b, 41, 1242-1246.
15. Hertog, M. G. L.; Kromhout, D.; Aravanis, C.; Blackburn, H.; Buzina, R.; Fidanza, F.; Giampaoli, S.; Jansen, A.; Menotti, A.; Nedeljkovic, S.; Pekkarinen, M.; Simic, B. S.; Toshima, H.; Feskens, E. J. M.; Hollman, P. C. H.; Katan, M. B. Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study. Arch. Intern. Med. 1995, 155, 381-386.
16. Hertog, M. G. L.; Feskens, E. J. M.; Kromhout, D. Antioxidant flavonols and coronary heart disease risk. Lancet 1997, 349, 699.
17. Justesen, U.; Knuthsen, P.; Leth, T. Quantitative analysis of flavonols, flavones, and flavanones in fruits, vegetables and beverages by high-performance liquid chromatography with photodiode array and mass spectrometric detection. J. Chromatogr. A 1998, 799, 101-110.
18. Keli, S. O.; Hertog, M. G. L.; Feskens, E. J. M.; Kromhout, D. Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study. Arch. Intern. Med. 1996, 156, 637-642.
19. Knekt, P.; Järvinen, R.; Reunanen, A.; Maatela, J. Flavonoid intake and coronary mortality in Finland: a cohort study. Br. Med. J. 1996, 312, 478-481.
20. Knekt, P.; Järvinen, R.; Seppänen, R.; Heliövaara, M.; Teppo, L.; Pukkala, E.; Aromaa, A. Dietary flavonoids and the risk of lung cancer and other malignant neoplasms. Am. J. Epidemiol. 1997, 146, 223-230.
21. Markham, K. R.; Bloor, S. J. Analysis and identification of flavonoids in practice. In Flavonoids in Health and Disease; Rice-Evans, C. A., Packer, L., Eds.; Dekker: New York, 1998; pp 1-33.
22. Prior, R. L.; Cao, G.; Martin, A.; Sofie, E.; McEwen, J.; O'Brien, C.; Lischner, N.; Ehlenfeldt, M.; Kalt, W.; Krewer, G.; Mainland, C. M. Antioxidant capacity as influenced by total phenolic and anthocyanin content, maturity, and variety of Vaccinium species. J. Agric. Food Chem. 1998, 46, 2686-2693.
23. Restas, M.; Seppänen, R.; Knuts, L.-R.; Hakala, P.; Karttila, V. Nutrient Composition of Foods; The Social Insurance Institution: Turku, Finland, 1997 (in Finnish).
24. Rice-Evans, C. A.; Miller, N. J. Structure-antioxidant activity relationships of flavonoids and isoflavonoids. In Flavonoids in Health and Disease; Rice-Evans, C. A., Packer, L., Eds.; Dekker: New York, 1998; pp 199-219.
25. Starke, H.; Herrmann, K. The phenolics of fruits. VIII. Changes in flavonol concentrations during fruit development. Z. Lebensm. Unters.-Forsch. 1976, 161, 131-135.
26. Statistics Finland. Finnish Household Survey 1990. Official Statistics of Finland, Income and Consumption; 1993; Vol. 3 (in Finnish).
27. Strube, M.; Dragsted, L. O.; Larsen, J. C. Naturally Occurring Antitumourigens. I. Plant Phenols. Nordiske Seminar-og Arbejdsrapporter 605; Nordic Council of Ministers: Copenhagen, Denmark, 1993.
28. Törrönen, R.; Häkkinen, S.; Karenlampi, S.; Mykkänen, H. Flavonoids and phenolic acids in selected berries. Cancer Lett. 1997, 114, 191-192.
29. Wildanger, W.; Herrmann, K. The phenolics of fruits. II. The flavonols of fruits. Z. Lebensm. Unters.-Forsch. 1973, 151, 103-108.