Dopamine-induced apoptosis is mediated by oxidative stress and is enhanced by cyanide in differentiated PC12 cells

Journal of Neurochemistry

Volumn 74, Issue 6, 2000, Pages 2296-2304

  Jones, Douglas C ^a   Gunasekar, Palur G ^a   Borowitz, Joseph L ^a   Isom, Gary E ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Apoptosis; Cyanide; Dopamine; Mitochondrial inhibition; Nitric oxide; Oxidative stress

Indexed keywords

ANTIOXIDANT; BUTHIONINE SULFOXIMINE; CYANIDE; DOPAMINE; LACTATE DEHYDROGENASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; NOMIFENSINE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOTOXICITY; GLUTATHIONE METABOLISM; NERVE DEGENERATION; NEUROTOXICITY; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL SURVIVAL; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; L-LACTATE DEHYDROGENASE; MITOCHONDRIA; NEURONS; NITRIC OXIDE; OXIDATIVE STRESS; PC12 CELLS; POTASSIUM CYANIDE; RATS;

ANIMALIA;

EID: 0034025513     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0742296.x     Document Type: Article

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