-
1
-
-
27144487469
-
In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog
-
Ahn S., and Joyner A.L. In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog. Nature 437 (2005) 894-897
-
(2005)
Nature
, vol.437
, pp. 894-897
-
-
Ahn, S.1
Joyner, A.L.2
-
2
-
-
0036096542
-
Identification of neural stem cells in the adult vertebrate brain
-
Alvarez-Buylla A., Seri B., and Doetsch F. Identification of neural stem cells in the adult vertebrate brain. Brain Res. Bull. 57 (2002) 751-758
-
(2002)
Brain Res. Bull.
, vol.57
, pp. 751-758
-
-
Alvarez-Buylla, A.1
Seri, B.2
Doetsch, F.3
-
3
-
-
33747513134
-
Notch signalling regulates stem cell numbers in vitro and in vivo
-
Androutsellis-Theotokis A., Leker R.R., Soldner F., Hoeppner D.J., Ravin R., Poser S.W., Rueger M.A., Bae S.-K., Kittappa R., and McKay R.D. Notch signalling regulates stem cell numbers in vitro and in vivo. Nature 442 (2006) 823-826
-
(2006)
Nature
, vol.442
, pp. 823-826
-
-
Androutsellis-Theotokis, A.1
Leker, R.R.2
Soldner, F.3
Hoeppner, D.J.4
Ravin, R.5
Poser, S.W.6
Rueger, M.A.7
Bae, S.-K.8
Kittappa, R.9
McKay, R.D.10
-
4
-
-
1842527386
-
Radial glia serve as neuronal progenitors in all regions of the central nervous system
-
Anthony T.E., Klein C., Fishell G., and Heintz N. Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron 41 (2004) 881-890
-
(2004)
Neuron
, vol.41
, pp. 881-890
-
-
Anthony, T.E.1
Klein, C.2
Fishell, G.3
Heintz, N.4
-
5
-
-
0037227099
-
Multipotent cell lineages in early mouse development depend on SOX2 function
-
Avilion A.A., Nicolis S.K., Pevny L.H., Perez L., Vivian N., and Lovell-Badge R. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev. 17 (2003) 126-140
-
(2003)
Genes Dev.
, vol.17
, pp. 126-140
-
-
Avilion, A.A.1
Nicolis, S.K.2
Pevny, L.H.3
Perez, L.4
Vivian, N.5
Lovell-Badge, R.6
-
6
-
-
19044397160
-
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
-
Bachoo R.M., Maher E.A., Ligon K.L., Sharpless N.E., Chan S.S., You M.J., Tang Y., DeFrances J., Stover E., Weissleder R., Rowitch D.H., Louis D.N., and DePinho R.A. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell 1 (2002) 269-277
-
(2002)
Cancer Cell
, vol.1
, pp. 269-277
-
-
Bachoo, R.M.1
Maher, E.A.2
Ligon, K.L.3
Sharpless, N.E.4
Chan, S.S.5
You, M.J.6
Tang, Y.7
DeFrances, J.8
Stover, E.9
Weissleder, R.10
Rowitch, D.H.11
Louis, D.N.12
DePinho, R.A.13
-
7
-
-
0030669218
-
Math1 is essential for genesis of cerebellar granule neurons
-
Ben-Arie N., Bellen H.J., Armstrong D.L., McCall A.E., Gordadze P.R., Guo Q., Matzuk M.M., and Zoghbi H.Y. Math1 is essential for genesis of cerebellar granule neurons. Nature 390 (1997) 169-172
-
(1997)
Nature
, vol.390
, pp. 169-172
-
-
Ben-Arie, N.1
Bellen, H.J.2
Armstrong, D.L.3
McCall, A.E.4
Gordadze, P.R.5
Guo, Q.6
Matzuk, M.M.7
Zoghbi, H.Y.8
-
8
-
-
2442535265
-
Review of the prognostic factors in medulloblastoma of children and adults
-
Brandes A.A., and Paris M.K. Review of the prognostic factors in medulloblastoma of children and adults. Crit. Rev. Oncol./Hematol. 50 (2004) 121
-
(2004)
Crit. Rev. Oncol./Hematol.
, vol.50
, pp. 121
-
-
Brandes, A.A.1
Paris, M.K.2
-
9
-
-
20544453888
-
Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice
-
Bruggeman S.W., Valk-Lingbeek M.E., van der Stoop P.P., Jacobs J.J., Kieboom K., Tanger E., Hulsman D., Leung C., Arsenijevic Y., Marino S., and van Lohuizen M. Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice. Genes Dev. 19 (2005) 1438-1443
-
(2005)
Genes Dev.
, vol.19
, pp. 1438-1443
-
-
Bruggeman, S.W.1
Valk-Lingbeek, M.E.2
van der Stoop, P.P.3
Jacobs, J.J.4
Kieboom, K.5
Tanger, E.6
Hulsman, D.7
Leung, C.8
Arsenijevic, Y.9
Marino, S.10
van Lohuizen, M.11
-
10
-
-
0242353154
-
Vertebrate neurogenesis is counteracted by Sox1-3 activity
-
Bylund M., Andersson E., Novitch B.G., and Muhr J. Vertebrate neurogenesis is counteracted by Sox1-3 activity. Nat. Neurosci. 6 (2003) 1162-1168
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 1162-1168
-
-
Bylund, M.1
Andersson, E.2
Novitch, B.G.3
Muhr, J.4
-
11
-
-
0037194887
-
LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal
-
Capela A., and Temple S. LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. Neuron 35 (2002) 865-875
-
(2002)
Neuron
, vol.35
, pp. 865-875
-
-
Capela, A.1
Temple, S.2
-
12
-
-
0034629129
-
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
-
Cheng T., Rodrigues N., Shen H., Yang Y., Dombkowski D., Sykes M., and Scadden D.T. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science 287 (2000) 1804-1808
-
(2000)
Science
, vol.287
, pp. 1804-1808
-
-
Cheng, T.1
Rodrigues, N.2
Shen, H.3
Yang, Y.4
Dombkowski, D.5
Sykes, M.6
Scadden, D.T.7
-
13
-
-
0037135177
-
Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
-
Chenn A., and Walsh C.A. Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science 297 (2002) 365-369
-
(2002)
Science
, vol.297
, pp. 365-369
-
-
Chenn, A.1
Walsh, C.A.2
-
14
-
-
33646045010
-
Stem cells and cancer: two faces of eve
-
Clarke M.F., and Fuller M. Stem cells and cancer: two faces of eve. Cell 124 (2006) 1111-1115
-
(2006)
Cell
, vol.124
, pp. 1111-1115
-
-
Clarke, M.F.1
Fuller, M.2
-
15
-
-
10344248682
-
Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development
-
Corrales J.D., Rocco G.L., Blaess S., Guo Q., and Joyner A.L. Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development 131 (2004) 5581-5590
-
(2004)
Development
, vol.131
, pp. 5581-5590
-
-
Corrales, J.D.1
Rocco, G.L.2
Blaess, S.3
Guo, Q.4
Joyner, A.L.5
-
16
-
-
0035425048
-
PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo
-
Dai C., Celestino J.C., Okada Y., Louis D.N., Fuller G.N., and Holland E.C. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev. 15 (2001) 1913-1925
-
(2001)
Genes Dev.
, vol.15
, pp. 1913-1925
-
-
Dai, C.1
Celestino, J.C.2
Okada, Y.3
Louis, D.N.4
Fuller, G.N.5
Holland, E.C.6
-
17
-
-
18644373850
-
The characteristics of astrocytomas and oligodendrogliomas are caused by two distinct and interchangeable signaling formats
-
Dai C., Lyustikman Y., Shih A., Hu X., Fuller G.N., Rosenblum M., and Holland E.C. The characteristics of astrocytomas and oligodendrogliomas are caused by two distinct and interchangeable signaling formats. Neoplasia 7 (2005) 397-406
-
(2005)
Neoplasia
, vol.7
, pp. 397-406
-
-
Dai, C.1
Lyustikman, Y.2
Shih, A.3
Hu, X.4
Fuller, G.N.5
Rosenblum, M.6
Holland, E.C.7
-
18
-
-
0027941902
-
A self-renewing multipotential stem cell in embryonic rat cerebral cortex
-
Davis A.A., and Temple S. A self-renewing multipotential stem cell in embryonic rat cerebral cortex. Nature 372 (1994) 263-266
-
(1994)
Nature
, vol.372
, pp. 263-266
-
-
Davis, A.A.1
Temple, S.2
-
19
-
-
0034681264
-
The multiple roles of PTEN in tumor suppression
-
Di Cristofano A., and Pandolfi P.P. The multiple roles of PTEN in tumor suppression. Cell 100 (2000) 387-390
-
(2000)
Cell
, vol.100
, pp. 387-390
-
-
Di Cristofano, A.1
Pandolfi, P.P.2
-
20
-
-
0038011863
-
Stem cells: self-renewal writ in blood
-
Dick J.E. Stem cells: self-renewal writ in blood. Nature 423 (2003) 231-233
-
(2003)
Nature
, vol.423
, pp. 231-233
-
-
Dick, J.E.1
-
21
-
-
0242321829
-
The glial identity of neural stem cells
-
Doetsch F. The glial identity of neural stem cells. Nat. Neurosci. 6 (2003) 1127-1134
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 1127-1134
-
-
Doetsch, F.1
-
22
-
-
0033040497
-
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
-
Doetsch F., Caille I., Lim D.A., Garcia-Verdugo J.M., and Alvarez-Buylla A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97 (1999) 703-716
-
(1999)
Cell
, vol.97
, pp. 703-716
-
-
Doetsch, F.1
Caille, I.2
Lim, D.A.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
23
-
-
0037137686
-
EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells
-
Doetsch F., Petreanu L., Caille I., Garcia-Verdugo J.M., and Alvarez-Buylla A. EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron 36 (2002) 1021-1034
-
(2002)
Neuron
, vol.36
, pp. 1021-1034
-
-
Doetsch, F.1
Petreanu, L.2
Caille, I.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
24
-
-
0031789814
-
Neurogenesis in the adult human hippocampus
-
Eriksson P.S., Perfilieva E., Bjork-Eriksson T., Alborn A.M., Nordborg C., Peterson D.A., and Gage F.H. Neurogenesis in the adult human hippocampus. Nat. Med. 4 (1998) 1313-1317
-
(1998)
Nat. Med.
, vol.4
, pp. 1313-1317
-
-
Eriksson, P.S.1
Perfilieva, E.2
Bjork-Eriksson, T.3
Alborn, A.M.4
Nordborg, C.5
Peterson, D.A.6
Gage, F.H.7
-
25
-
-
31444452060
-
Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing
-
Ferres-Marco D., Gutierrez-Garcia I., Vallejo D.M., Bolivar J., Gutierrez-Avino F.J., and Dominguez M. Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing. Nature 439 (2006) 430-436
-
(2006)
Nature
, vol.439
, pp. 430-436
-
-
Ferres-Marco, D.1
Gutierrez-Garcia, I.2
Vallejo, D.M.3
Bolivar, J.4
Gutierrez-Avino, F.J.5
Dominguez, M.6
-
26
-
-
4444378766
-
Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain
-
Ferri A.L., Cavallaro M., Braida D., Di Cristofano A., Canta A., Vezzani A., Ottolenghi S., Pandolfi P.P., Sala M., DeBiasi S., and Nicolis S.K. Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development 131 (2004) 3805-3819
-
(2004)
Development
, vol.131
, pp. 3805-3819
-
-
Ferri, A.L.1
Cavallaro, M.2
Braida, D.3
Di Cristofano, A.4
Canta, A.5
Vezzani, A.6
Ottolenghi, S.7
Pandolfi, P.P.8
Sala, M.9
DeBiasi, S.10
Nicolis, S.K.11
-
28
-
-
0344256592
-
Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro
-
Gabay L., Lowell S., Rubin L.L., and Anderson D.J. Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Neuron 40 (2003) 485-499
-
(2003)
Neuron
, vol.40
, pp. 485-499
-
-
Gabay, L.1
Lowell, S.2
Rubin, L.L.3
Anderson, D.J.4
-
29
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
Galli R., Binda E., Orfanelli U., Cipelletti B., Gritti A., De Vitis S., Fiocco R., Foroni C., Dimeco F., and Vescovi A. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res. 64 (2004) 7011-7021
-
(2004)
Cancer Res.
, vol.64
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
Cipelletti, B.4
Gritti, A.5
De Vitis, S.6
Fiocco, R.7
Foroni, C.8
Dimeco, F.9
Vescovi, A.10
-
30
-
-
0030866154
-
Altered neural cell fates and medulloblastoma in mouse patched mutants
-
Goodrich L.V., Milenkovic L., Higgins K.M., and Scott M.P. Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277 (1997) 1109-1113
-
(1997)
Science
, vol.277
, pp. 1109-1113
-
-
Goodrich, L.V.1
Milenkovic, L.2
Higgins, K.M.3
Scott, M.P.4
-
31
-
-
33747339465
-
Wnt signaling: multiple pathways, multiple receptors and multiple transcription factors
-
Gordon M.D., and Nusse R. Wnt signaling: multiple pathways, multiple receptors and multiple transcription factors. J Biol Chem 281 (2006) 22429-22433
-
(2006)
J Biol Chem
, vol.281
, pp. 22429-22433
-
-
Gordon, M.D.1
Nusse, R.2
-
32
-
-
0041880122
-
SOX2 functions to maintain neural progenitor identity
-
Graham V., Khudyakov J., Ellis P., and Pevny L. SOX2 functions to maintain neural progenitor identity. Neuron 39 (2003) 749-765
-
(2003)
Neuron
, vol.39
, pp. 749-765
-
-
Graham, V.1
Khudyakov, J.2
Ellis, P.3
Pevny, L.4
-
33
-
-
0035824396
-
Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo
-
Groszer M., Erickson R., Scripture-Adams D.D., Lesche R., Trumpp A., Zack J.A., Kornblum H.I., Liu X., and Wu H. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science 294 (2001) 2186-2189
-
(2001)
Science
, vol.294
, pp. 2186-2189
-
-
Groszer, M.1
Erickson, R.2
Scripture-Adams, D.D.3
Lesche, R.4
Trumpp, A.5
Zack, J.A.6
Kornblum, H.I.7
Liu, X.8
Wu, H.9
-
34
-
-
30444455577
-
PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry
-
Groszer M., Erickson R., Scripture-Adams D.D., Dougherty J.D., Le Belle J., Zack J.A., Geschwind D.H., Liu X., Kornblum H.I., and Wu H. PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry. Proc. Natl. Acad Sci. U. S. A. 103 (2006) 111-116
-
(2006)
Proc. Natl. Acad Sci. U. S. A.
, vol.103
, pp. 111-116
-
-
Groszer, M.1
Erickson, R.2
Scripture-Adams, D.D.3
Dougherty, J.D.4
Le Belle, J.5
Zack, J.A.6
Geschwind, D.H.7
Liu, X.8
Kornblum, H.I.9
Wu, H.10
-
35
-
-
26944459216
-
Molecular regulation of adult CNS neurogenesis: an integrated view
-
Hagg T. Molecular regulation of adult CNS neurogenesis: an integrated view. Trends Neurosci 28 (2005) 589-595
-
(2005)
Trends Neurosci
, vol.28
, pp. 589-595
-
-
Hagg, T.1
-
36
-
-
0042967678
-
BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect
-
Hallahan A.R., Pritchard J.I., Chandraratna R.A., Ellenbogen R.G., Geyer J.R., Overland R.P., Strand A.D., Tapscott S.J., and Olson J.M. BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect. Nat. Med. 9 (2003) 1033-1038
-
(2003)
Nat. Med.
, vol.9
, pp. 1033-1038
-
-
Hallahan, A.R.1
Pritchard, J.I.2
Chandraratna, R.A.3
Ellenbogen, R.G.4
Geyer, J.R.5
Overland, R.P.6
Strand, A.D.7
Tapscott, S.J.8
Olson, J.M.9
-
37
-
-
0344735881
-
Cancerous stem cells can arise from pediatric brain tumors
-
Hemmati H.D., Nakano I., Lazareff J.A., Masterman-Smith M., Geschwind D.H., Bronner-Fraser M., and Kornblum H.I. Cancerous stem cells can arise from pediatric brain tumors. Proc. Natl. Acad Sci. U. S. A. 100 (2003) 15178-15183
-
(2003)
Proc. Natl. Acad Sci. U. S. A.
, vol.100
, pp. 15178-15183
-
-
Hemmati, H.D.1
Nakano, I.2
Lazareff, J.A.3
Masterman-Smith, M.4
Geschwind, D.H.5
Bronner-Fraser, M.6
Kornblum, H.I.7
-
38
-
-
0037206890
-
N-CoR controls differentiation of neural stem cells into astrocytes
-
Hermanson O., Jepsen K., and Rosenfeld M.G. N-CoR controls differentiation of neural stem cells into astrocytes. Nature 419 (2002) 934-939
-
(2002)
Nature
, vol.419
, pp. 934-939
-
-
Hermanson, O.1
Jepsen, K.2
Rosenfeld, M.G.3
-
39
-
-
4644306516
-
A distinct "side population" of cells with high drug efflux capacity in human tumor cells
-
Hirschmann-Jax C., Foster A.E., Wulf G.G., Nuchtern J.G., Jax T.W., Gobel U., Goodell M.A., and Brenner M.K. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc. Natl. Acad Sci. U. S. A. 101 (2004) 14228-14233
-
(2004)
Proc. Natl. Acad Sci. U. S. A.
, vol.101
, pp. 14228-14233
-
-
Hirschmann-Jax, C.1
Foster, A.E.2
Wulf, G.G.3
Nuchtern, J.G.4
Jax, T.W.5
Gobel, U.6
Goodell, M.A.7
Brenner, M.K.8
-
40
-
-
0036336528
-
Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain
-
Hitoshi S., Tropepe V., Ekker M., and van der Kooy D. Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain. Development 129 (2002) 233-244
-
(2002)
Development
, vol.129
, pp. 233-244
-
-
Hitoshi, S.1
Tropepe, V.2
Ekker, M.3
van der Kooy, D.4
-
41
-
-
3543086157
-
Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling
-
Hitoshi S., Seaberg R.M., Koscik C., Alexson T., Kusunoki S., Kanazawa I., Tsuji S., and van der Kooy D. Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling. Genes Dev. 18 (2004) 1806-1811
-
(2004)
Genes Dev.
, vol.18
, pp. 1806-1811
-
-
Hitoshi, S.1
Seaberg, R.M.2
Koscik, C.3
Alexson, T.4
Kusunoki, S.5
Kanazawa, I.6
Tsuji, S.7
van der Kooy, D.8
-
42
-
-
0034612289
-
Glioblastoma multiforme: the terminator
-
Holland E.C. Glioblastoma multiforme: the terminator. Proc. Natl. Acad Sci. U. S. A. 97 (2000) 6242-6244
-
(2000)
Proc. Natl. Acad Sci. U. S. A.
, vol.97
, pp. 6242-6244
-
-
Holland, E.C.1
-
43
-
-
0036737914
-
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
-
Ignatova T.N., Kukekov V.G., Laywell E.D., Suslov O.N., Vrionis F.D., and Steindler D.A. Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia 39 (2002) 193-206
-
(2002)
Glia
, vol.39
, pp. 193-206
-
-
Ignatova, T.N.1
Kukekov, V.G.2
Laywell, E.D.3
Suslov, O.N.4
Vrionis, F.D.5
Steindler, D.A.6
-
44
-
-
7244250309
-
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
-
Ito K., Hirao A., Arai F., Matsuoka S., Takubo K., Hamaguchi I., Nomiyama K., Hosokawa K., Sakurada K., Nakagata N., Ikeda Y., Mak T.W., and Suda T. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 431 (2004) 997-1002
-
(2004)
Nature
, vol.431
, pp. 997-1002
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Matsuoka, S.4
Takubo, K.5
Hamaguchi, I.6
Nomiyama, K.7
Hosokawa, K.8
Sakurada, K.9
Nakagata, N.10
Ikeda, Y.11
Mak, T.W.12
Suda, T.13
-
45
-
-
33745880884
-
PDGFRalpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling
-
Jackson E.L., Garcia-Verdugo J.M., Gil-Perotin S., Roy M., Quinones-Hinojosa A., Vandenberg S., and Alvarez-Buylla A. PDGFRalpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling. Neuron 51 (2006) 187-199
-
(2006)
Neuron
, vol.51
, pp. 187-199
-
-
Jackson, E.L.1
Garcia-Verdugo, J.M.2
Gil-Perotin, S.3
Roy, M.4
Quinones-Hinojosa, A.5
Vandenberg, S.6
Alvarez-Buylla, A.7
-
46
-
-
0033552813
-
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
-
Jacobs J.J., Kieboom K., Marino S., DePinho R.A., and van Lohuizen M. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397 (1999) 164-168
-
(1999)
Nature
, vol.397
, pp. 164-168
-
-
Jacobs, J.J.1
Kieboom, K.2
Marino, S.3
DePinho, R.A.4
van Lohuizen, M.5
-
47
-
-
33745321352
-
Stem cells: good, bad and reformable
-
Janzen V., and Scadden D.T. Stem cells: good, bad and reformable. Nature 441 (2006) 418-419
-
(2006)
Nature
, vol.441
, pp. 418-419
-
-
Janzen, V.1
Scadden, D.T.2
-
49
-
-
0037232580
-
Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
-
Kenney A.M., Cole M.D., and Rowitch D.H. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development 130 (2003) 15-28
-
(2003)
Development
, vol.130
, pp. 15-28
-
-
Kenney, A.M.1
Cole, M.D.2
Rowitch, D.H.3
-
50
-
-
20444433526
-
Gli1 is important for medulloblastoma formation in Ptc1+/- mice
-
Kimura H., Stephen D., Joyner A., and Curran T. Gli1 is important for medulloblastoma formation in Ptc1+/- mice. Oncogene 24 (2005) 4026-4036
-
(2005)
Oncogene
, vol.24
, pp. 4026-4036
-
-
Kimura, H.1
Stephen, D.2
Joyner, A.3
Curran, T.4
-
51
-
-
15444377643
-
p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity
-
Kippin T.E., Martens D.J., and van der Kooy D. p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity. Genes Dev. 19 (2005) 756-767
-
(2005)
Genes Dev.
, vol.19
, pp. 756-767
-
-
Kippin, T.E.1
Martens, D.J.2
van der Kooy, D.3
-
52
-
-
27744521637
-
Cerebellum- and forebrain-derived stem cells possess intrinsic regional character
-
Klein C., Butt S.J., Machold R.P., Johnson J.E., and Fishell G. Cerebellum- and forebrain-derived stem cells possess intrinsic regional character. Development 132 (2005) 4497-4508
-
(2005)
Development
, vol.132
, pp. 4497-4508
-
-
Klein, C.1
Butt, S.J.2
Machold, R.P.3
Johnson, J.E.4
Fishell, G.5
-
53
-
-
0037108268
-
N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
-
Knoepfler P.S., Cheng P.F., and Eisenman R.N. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev. 16 (2002) 2699-2712
-
(2002)
Genes Dev.
, vol.16
, pp. 2699-2712
-
-
Knoepfler, P.S.1
Cheng, P.F.2
Eisenman, R.N.3
-
54
-
-
0034622930
-
Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells
-
Kondo T., and Raff M. Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells. Science 289 (2000) 1754-1757
-
(2000)
Science
, vol.289
, pp. 1754-1757
-
-
Kondo, T.1
Raff, M.2
-
55
-
-
9944266165
-
Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells
-
Kondo T., and Raff M. Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells. Genes Dev. 18 (2004) 2963-2972
-
(2004)
Genes Dev.
, vol.18
, pp. 2963-2972
-
-
Kondo, T.1
Raff, M.2
-
56
-
-
1642474273
-
Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
-
Kondo T., Setoguchi T., and Taga T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc. Natl. Acad Sci. U. S. A. 101 (2004) 781-786
-
(2004)
Proc. Natl. Acad Sci. U. S. A.
, vol.101
, pp. 781-786
-
-
Kondo, T.1
Setoguchi, T.2
Taga, T.3
-
57
-
-
0037218819
-
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
-
Lai K., Kaspar B.K., Gage F.H., and Schaffer D.V. Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat. Neurosci. 6 (2003) 21-27
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 21-27
-
-
Lai, K.1
Kaspar, B.K.2
Gage, F.H.3
Schaffer, D.V.4
-
58
-
-
22844437215
-
Isolation of neural stem cells from the postnatal cerebellum
-
Lee A., Kessler J.D., Read T.A., Kaiser C., Corbeil D., Huttner W.B., Johnson J.E., and Wechsler-Reya R.J. Isolation of neural stem cells from the postnatal cerebellum. Nat. Neurosci. 8 (2005) 723-729
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 723-729
-
-
Lee, A.1
Kessler, J.D.2
Read, T.A.3
Kaiser, C.4
Corbeil, D.5
Huttner, W.B.6
Johnson, J.E.7
Wechsler-Reya, R.J.8
-
59
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J., and Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423 (2003) 255-260
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
60
-
-
1642633053
-
Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
-
Leung C., Lingbeek M., Shakhova O., Liu J., Tanger E., Saremaslani P., Van Lohuizen M., and Marino S. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature 428 (2004) 337-341
-
(2004)
Nature
, vol.428
, pp. 337-341
-
-
Leung, C.1
Lingbeek, M.2
Shakhova, O.3
Liu, J.4
Tanger, E.5
Saremaslani, P.6
Van Lohuizen, M.7
Marino, S.8
-
61
-
-
33646358694
-
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
-
Lee J., Kotliarova S., Kotliarov Y., Li A., Su Q., Donin N.M., Pastorino S., Purow B.W., Christopher N., Zhang W., Park J.K., and Fine H.A. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 9 (2006) 391-403
-
(2006)
Cancer Cell
, vol.9
, pp. 391-403
-
-
Lee, J.1
Kotliarova, S.2
Kotliarov, Y.3
Li, A.4
Su, Q.5
Donin, N.M.6
Pastorino, S.7
Purow, B.W.8
Christopher, N.9
Zhang, W.10
Park, J.K.11
Fine, H.A.12
-
62
-
-
0346732391
-
Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis
-
Li H.S., Wang D., Shen Q., Schonemann M.D., Gorski J.A., Jones K.R., Temple S., Jan L.Y., and Jan Y.N. Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron 40 (2003) 1105-1118
-
(2003)
Neuron
, vol.40
, pp. 1105-1118
-
-
Li, H.S.1
Wang, D.2
Shen, Q.3
Schonemann, M.D.4
Gorski, J.A.5
Jones, K.R.6
Temple, S.7
Jan, L.Y.8
Jan, Y.N.9
-
63
-
-
0038277050
-
Mouse embryos cloned from brain tumors
-
Li L., Connelly M.C., Wetmore C., Curran T., and Morgan J.I. Mouse embryos cloned from brain tumors. Cancer Res. 63 (2003) 2733-2736
-
(2003)
Cancer Res.
, vol.63
, pp. 2733-2736
-
-
Li, L.1
Connelly, M.C.2
Wetmore, C.3
Curran, T.4
Morgan, J.I.5
-
64
-
-
0034517812
-
Noggin antagonizes BMP signaling to create a niche for adult neurogenesis
-
Lim D.A., Tramontin A.D., Trevejo J.M., Herrera D.G., Garcia-Verdugo J.M., and Alvarez-Buylla A. Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron 28 (2000) 713-726
-
(2000)
Neuron
, vol.28
, pp. 713-726
-
-
Lim, D.A.1
Tramontin, A.D.2
Trevejo, J.M.3
Herrera, D.G.4
Garcia-Verdugo, J.M.5
Alvarez-Buylla, A.6
-
65
-
-
5044234932
-
SVZa neural stem cells differentiate into distinct lineages in response to BMP4
-
Liu S.-Y., Zhang Z.-Y., Song Y.-C., Qiu K.-J., Zhang K.-C., An N., Zhou Z., Cai W.-Q., and Yang H. SVZa neural stem cells differentiate into distinct lineages in response to BMP4. Exp. Neurol. 190 (2004) 109-121
-
(2004)
Exp. Neurol.
, vol.190
, pp. 109-121
-
-
Liu, S.-Y.1
Zhang, Z.-Y.2
Song, Y.-C.3
Qiu, K.-J.4
Zhang, K.-C.5
An, N.6
Zhou, Z.7
Cai, W.-Q.8
Yang, H.9
-
66
-
-
8444251784
-
The Wnt signaling pathway in development and disease
-
Logan C.Y., and Nusse R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20 (2004) 781-810
-
(2004)
Annu. Rev. Cell Dev. Biol.
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
67
-
-
25644435002
-
Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors
-
Machold R., and Fishell G. Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors. Neuron 48 (2005) 17-24
-
(2005)
Neuron
, vol.48
, pp. 17-24
-
-
Machold, R.1
Fishell, G.2
-
68
-
-
10744230965
-
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches
-
Machold R., Hayashi S., Rutlin M., Muzumdar M.D., Nery S., Corbin J.G., Gritli-Linde A., Dellovade T., Porter J.A., Rubin L.L., Dudek H., McMahon A.P., and Fishell G. Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron 39 (2003) 937-950
-
(2003)
Neuron
, vol.39
, pp. 937-950
-
-
Machold, R.1
Hayashi, S.2
Rutlin, M.3
Muzumdar, M.D.4
Nery, S.5
Corbin, J.G.6
Gritli-Linde, A.7
Dellovade, T.8
Porter, J.A.9
Rubin, L.L.10
Dudek, H.11
McMahon, A.P.12
Fishell, G.13
-
69
-
-
0034518641
-
Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage
-
Malatesta P., Hartfuss E., and Gotz M. Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage. Development 127 (2000) 5253-5263
-
(2000)
Development
, vol.127
, pp. 5253-5263
-
-
Malatesta, P.1
Hartfuss, E.2
Gotz, M.3
-
70
-
-
0037421992
-
Neuronal or glial progeny: regional differences in radial glia fate
-
Malatesta P., Hack M.A., Hartfuss E., Kettenmann H., Klinkert W., Kirchhoff F., and Gotz M. Neuronal or glial progeny: regional differences in radial glia fate. Neuron 37 (2003) 751-764
-
(2003)
Neuron
, vol.37
, pp. 751-764
-
-
Malatesta, P.1
Hack, M.A.2
Hartfuss, E.3
Kettenmann, H.4
Klinkert, W.5
Kirchhoff, F.6
Gotz, M.7
-
71
-
-
11844301282
-
Medulloblastoma: developmental mechanisms out of control
-
Marino S. Medulloblastoma: developmental mechanisms out of control. Trends Mol. Med. 11 (2005) 17-22
-
(2005)
Trends Mol. Med.
, vol.11
, pp. 17-22
-
-
Marino, S.1
-
72
-
-
9244239811
-
G1 cell-cycle control and cancer
-
Massague J. G1 cell-cycle control and cancer. Nature 432 (2004) 298
-
(2004)
Nature
, vol.432
, pp. 298
-
-
Massague, J.1
-
73
-
-
0030894092
-
Stem cells in the central nervous system
-
McKay R. Stem cells in the central nervous system. Science 276 (1997) 66-71
-
(1997)
Science
, vol.276
, pp. 66-71
-
-
McKay, R.1
-
74
-
-
32244436592
-
p53 suppresses the self-renewal of adult neural stem cells
-
Meletis K., Wirta V., Hede S.M., Nister M., Lundeberg J., and Frisen J. p53 suppresses the self-renewal of adult neural stem cells. Development 133 (2006) 363-369
-
(2006)
Development
, vol.133
, pp. 363-369
-
-
Meletis, K.1
Wirta, V.2
Hede, S.M.3
Nister, M.4
Lundeberg, J.5
Frisen, J.6
-
76
-
-
5044224775
-
DNA-microarray analysis of brain cancer: molecular classification for therapy
-
Mischel P.S., Cloughesy T.F., and Nelson S.F. DNA-microarray analysis of brain cancer: molecular classification for therapy. Nat. Rev., Neurosci. 5 (2004) 782-792
-
(2004)
Nat. Rev., Neurosci.
, vol.5
, pp. 782-792
-
-
Mischel, P.S.1
Cloughesy, T.F.2
Nelson, S.F.3
-
77
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
Molofsky A.V., Pardal R., Iwashita T., Park I.K., Clarke M.F., and Morrison S.J. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425 (2003) 962-967
-
(2003)
Nature
, vol.425
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
Park, I.K.4
Clarke, M.F.5
Morrison, S.J.6
-
78
-
-
22344449361
-
Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
-
Molofsky A.V., He S., Bydon M., Morrison S.J., and Pardal R. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev. 19 (2005) 1432-1437
-
(2005)
Genes Dev.
, vol.19
, pp. 1432-1437
-
-
Molofsky, A.V.1
He, S.2
Bydon, M.3
Morrison, S.J.4
Pardal, R.5
-
79
-
-
0035825670
-
Neurons derived from radial glial cells establish radial units in neocortex
-
Noctor S.C., Flint A.C., Weissman T.A., Dammerman R.S., and Kriegstein A.R. Neurons derived from radial glial cells establish radial units in neocortex. Nature 409 (2001) 714-720
-
(2001)
Nature
, vol.409
, pp. 714-720
-
-
Noctor, S.C.1
Flint, A.C.2
Weissman, T.A.3
Dammerman, R.S.4
Kriegstein, A.R.5
-
80
-
-
16444368462
-
Genetic pathways to glioblastomas
-
Ohgaki H. Genetic pathways to glioblastomas. Neuropathology 25 (2005) 1-7
-
(2005)
Neuropathology
, vol.25
, pp. 1-7
-
-
Ohgaki, H.1
-
81
-
-
2942700004
-
Getting at the root and stem of brain tumors
-
Oliver T.G., and Wechsler-Reya R.J. Getting at the root and stem of brain tumors. Neuron 42 (2004) 885-888
-
(2004)
Neuron
, vol.42
, pp. 885-888
-
-
Oliver, T.G.1
Wechsler-Reya, R.J.2
-
82
-
-
13344282140
-
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain
-
Palma V., Lim D.A., Dahmane N., Sanchez P., Brionne T.C., Herzberg C.D., Gitton Y., Carleton A., Alvarez-Buylla A., and Ruiz i Altaba A. Sonic hedgehog controls stem cell behavior in the postnatal and adult brain. Development 132 (2005) 335-344
-
(2005)
Development
, vol.132
, pp. 335-344
-
-
Palma, V.1
Lim, D.A.2
Dahmane, N.3
Sanchez, P.4
Brionne, T.C.5
Herzberg, C.D.6
Gitton, Y.7
Carleton, A.8
Alvarez-Buylla, A.9
Ruiz i Altaba, A.10
-
83
-
-
0031797679
-
Plasticity and stem cells in the vertebrate nervous system
-
Panchision D., Hazel T., and McKay R. Plasticity and stem cells in the vertebrate nervous system. Curr. Opin. Cell Biol. 10 (1998) 727-733
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 727-733
-
-
Panchision, D.1
Hazel, T.2
McKay, R.3
-
84
-
-
0345059767
-
Applying the principles of stem-cell biology to cancer
-
Pardal R., Clarke M.F., and Morrison S.J. Applying the principles of stem-cell biology to cancer. Nat. Rev., Cancer 3 (2003) 895-902
-
(2003)
Nat. Rev., Cancer
, vol.3
, pp. 895-902
-
-
Pardal, R.1
Clarke, M.F.2
Morrison, S.J.3
-
85
-
-
0034055649
-
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation
-
Park H.L., Bai C., Platt K.A., Matise M.P., Beeghly A., Hui C.C., Nakashima M., and Joyner A.L. Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development 127 (2000) 1593-1605
-
(2000)
Development
, vol.127
, pp. 1593-1605
-
-
Park, H.L.1
Bai, C.2
Platt, K.A.3
Matise, M.P.4
Beeghly, A.5
Hui, C.C.6
Nakashima, M.7
Joyner, A.L.8
-
86
-
-
0038349957
-
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
-
Park I.K., Qian D., Kiel M., Becker M.W., Pihalja M., Weissman I.L., Morrison S.J., and Clarke M.F. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423 (2003) 302-305
-
(2003)
Nature
, vol.423
, pp. 302-305
-
-
Park, I.K.1
Qian, D.2
Kiel, M.3
Becker, M.W.4
Pihalja, M.5
Weissman, I.L.6
Morrison, S.J.7
Clarke, M.F.8
-
87
-
-
0141483064
-
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
-
Passegue E., Jamieson C.H., Ailles L.E., and Weissman I.L. Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?. Proc. Natl. Acad Sci. U. S. A. 100 Suppl 1 (2003) 11842-11849
-
(2003)
Proc. Natl. Acad Sci. U. S. A.
, vol.100
, Issue.SUPPL. 1
, pp. 11842-11849
-
-
Passegue, E.1
Jamieson, C.H.2
Ailles, L.E.3
Weissman, I.L.4
-
88
-
-
7044269527
-
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells
-
Passegue E., Wagner E.F., and Weissman I.L. JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell 119 (2004) 431-443
-
(2004)
Cell
, vol.119
, pp. 431-443
-
-
Passegue, E.1
Wagner, E.F.2
Weissman, I.L.3
-
89
-
-
0037206889
-
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
-
Petersen P.H., Zou K., Hwang J.K., Jan Y.N., and Zhong W. Progenitor cell maintenance requires numb and numblike during mouse neurogenesis. Nature 419 (2002) 929-934
-
(2002)
Nature
, vol.419
, pp. 929-934
-
-
Petersen, P.H.1
Zou, K.2
Hwang, J.K.3
Jan, Y.N.4
Zhong, W.5
-
90
-
-
3342938070
-
Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis
-
Petersen P.H., Zou K., Krauss S., and Zhong W. Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat. Neurosci. 7 (2004) 803-811
-
(2004)
Nat. Neurosci.
, vol.7
, pp. 803-811
-
-
Petersen, P.H.1
Zou, K.2
Krauss, S.3
Zhong, W.4
-
91
-
-
0037165140
-
Prediction of central nervous system embryonal tumour outcome based on gene expression
-
Pomeroy S.L., Tamayo P., Gaasenbeek M., Sturla L.M., Angelo M., McLaughlin M.E., Kim J.Y., Goumnerova L.C., Black P.M., Lau C., Allen J.C., Zagzag D., Olson J.M., Curran T., Wetmore C., Biegel J.A., Poggio T., Mukherjee S., Rifkin R., Califano A., Stolovitzky G., Louis D.N., Mesirov J.P., Lander E.S., and Golub T.R. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 415 (2002) 436-442
-
(2002)
Nature
, vol.415
, pp. 436-442
-
-
Pomeroy, S.L.1
Tamayo, P.2
Gaasenbeek, M.3
Sturla, L.M.4
Angelo, M.5
McLaughlin, M.E.6
Kim, J.Y.7
Goumnerova, L.C.8
Black, P.M.9
Lau, C.10
Allen, J.C.11
Zagzag, D.12
Olson, J.M.13
Curran, T.14
Wetmore, C.15
Biegel, J.A.16
Poggio, T.17
Mukherjee, S.18
Rifkin, R.19
Califano, A.20
Stolovitzky, G.21
Louis, D.N.22
Mesirov, J.P.23
Lander, E.S.24
Golub, T.R.25
more..
-
92
-
-
0031688990
-
Intrinsic programs of patterned cell lineages in isolated vertebrate CNS ventricular zone cells
-
Qian X., Goderie S.K., Shen Q., Stern J.H., and Temple S. Intrinsic programs of patterned cell lineages in isolated vertebrate CNS ventricular zone cells. Development 125 (1998) 3143-3152
-
(1998)
Development
, vol.125
, pp. 3143-3152
-
-
Qian, X.1
Goderie, S.K.2
Shen, Q.3
Stern, J.H.4
Temple, S.5
-
93
-
-
0033636521
-
Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells
-
Qian X., Shen Q., Goderie S.K., He W., Capela A., Davis A.A., and Temple S. Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells. Neuron 28 (2000) 69-80
-
(2000)
Neuron
, vol.28
, pp. 69-80
-
-
Qian, X.1
Shen, Q.2
Goderie, S.K.3
He, W.4
Capela, A.5
Davis, A.A.6
Temple, S.7
-
94
-
-
0037902082
-
c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice
-
Rao G., Pedone C.A., Coffin C.M., Holland E.C., and Fults D.W. c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice. Neoplasia 5 (2003) 198-204
-
(2003)
Neoplasia
, vol.5
, pp. 198-204
-
-
Rao, G.1
Pedone, C.A.2
Coffin, C.M.3
Holland, E.C.4
Fults, D.W.5
-
95
-
-
4444273153
-
Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice
-
Rao G., Pedone C.A., Valle L.D., Reiss K., Holland E.C., and Fults D.W. Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice. Oncogene 23 (2004) 6156-6162
-
(2004)
Oncogene
, vol.23
, pp. 6156-6162
-
-
Rao, G.1
Pedone, C.A.2
Valle, L.D.3
Reiss, K.4
Holland, E.C.5
Fults, D.W.6
-
96
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T., and Clevers H. Wnt signalling in stem cells and cancer. Nature 434 (2005) 843-850
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
97
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T., Morrison S.J., Clarke M.F., and Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 414 (2001) 105-111
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
98
-
-
0026535505
-
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
-
Reynolds B.A., and Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255 (1992) 1707-1710
-
(1992)
Science
, vol.255
, pp. 1707-1710
-
-
Reynolds, B.A.1
Weiss, S.2
-
99
-
-
0035899505
-
Purification of a pluripotent neural stem cell from the adult mouse brain
-
Rietze R.L., Valcanis H., Brooker G.F., Thomas T., Voss A.K., and Bartlett P.F. Purification of a pluripotent neural stem cell from the adult mouse brain. Nature 412 (2001) 736-739
-
(2001)
Nature
, vol.412
, pp. 736-739
-
-
Rietze, R.L.1
Valcanis, H.2
Brooker, G.F.3
Thomas, T.4
Voss, A.K.5
Bartlett, P.F.6
-
100
-
-
4043147087
-
Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling
-
Rios I., Alvarez-Rodriguez R., Marti E., and Pons S. Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling. Development 131 (2004) 3159-3168
-
(2004)
Development
, vol.131
, pp. 3159-3168
-
-
Rios, I.1
Alvarez-Rodriguez, R.2
Marti, E.3
Pons, S.4
-
101
-
-
4544285754
-
Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice
-
Romer J.T., Kimura H., Magdaleno S., Sasai K., Fuller C., Baines H., Connelly M., Stewart C.F., Gould S., Rubin L.L., and Curran T. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. Cancer Cell 6 (2004) 229-240
-
(2004)
Cancer Cell
, vol.6
, pp. 229-240
-
-
Romer, J.T.1
Kimura, H.2
Magdaleno, S.3
Sasai, K.4
Fuller, C.5
Baines, H.6
Connelly, M.7
Stewart, C.F.8
Gould, S.9
Rubin, L.L.10
Curran, T.11
-
102
-
-
0036559186
-
Gli and hedgehog in cancer: tumours, embryos and stem cells
-
Ruiz i Altaba A., Sanchez P., and Dahmane N. Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat. Rev., Cancer 2 (2002) 361-372
-
(2002)
Nat. Rev., Cancer
, vol.2
, pp. 361-372
-
-
Ruiz i Altaba, A.1
Sanchez, P.2
Dahmane, N.3
-
103
-
-
5644266355
-
Expression of MATH1, a marker of cerebellar granule cell progenitors, identifies different medulloblastoma sub-types
-
Salsano E., Pollo B., Eoli M., Giordana M.T., and Finocchiaro G. Expression of MATH1, a marker of cerebellar granule cell progenitors, identifies different medulloblastoma sub-types. Neurosci. Lett. 370 (2004) 180-185
-
(2004)
Neurosci. Lett.
, vol.370
, pp. 180-185
-
-
Salsano, E.1
Pollo, B.2
Eoli, M.3
Giordana, M.T.4
Finocchiaro, G.5
-
104
-
-
1442354188
-
Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration
-
Sanai N., Tramontin A.D., Quinones-Hinojosa A., Barbaro N.M., Gupta N., Kunwar S., Lawton M.T., McDermott M.W., Parsa A.T., Manuel-Garcia Verdugo J., Berger M.S., and Alvarez-Buylla A. Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration. Nature 427 (2004) 740-744
-
(2004)
Nature
, vol.427
, pp. 740-744
-
-
Sanai, N.1
Tramontin, A.D.2
Quinones-Hinojosa, A.3
Barbaro, N.M.4
Gupta, N.5
Kunwar, S.6
Lawton, M.T.7
McDermott, M.W.8
Parsa, A.T.9
Manuel-Garcia Verdugo, J.10
Berger, M.S.11
Alvarez-Buylla, A.12
-
105
-
-
0347719238
-
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
-
Shi Y., Chichung Lie D., Taupin P., Nakashima K., Ray J., Yu R.T., Gage F.H., and Evans R.M. Expression and function of orphan nuclear receptor TLX in adult neural stem cells. Nature 427 (2004) 78-83
-
(2004)
Nature
, vol.427
, pp. 78-83
-
-
Shi, Y.1
Chichung Lie, D.2
Taupin, P.3
Nakashima, K.4
Ray, J.5
Yu, R.T.6
Gage, F.H.7
Evans, R.M.8
-
107
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh S.K., Clarke I.D., Terasaki M., Bonn V.E., Hawkins C., Squire J., and Dirks P.B. Identification of a cancer stem cell in human brain tumors. Cancer Res. 63 (2003) 5821-5828
-
(2003)
Cancer Res.
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
Dirks, P.B.7
-
108
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh S.K., Hawkins C., Clarke I.D., Squire J.A., Bayani J., Hide T., Henkelman R.M., Cusimano M.D., and Dirks P.B. Identification of human brain tumour initiating cells. Nature 432 (2004) 396
-
(2004)
Nature
, vol.432
, pp. 396
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
110
-
-
0141922983
-
Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1
-
Smith K.S., Chanda S.K., Lingbeek M., Ross D.T., Botstein D., van Lohuizen M., and Cleary M.L. Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1. Mol. Cell 12 (2003) 393-400
-
(2003)
Mol. Cell
, vol.12
, pp. 393-400
-
-
Smith, K.S.1
Chanda, S.K.2
Lingbeek, M.3
Ross, D.T.4
Botstein, D.5
van Lohuizen, M.6
Cleary, M.L.7
-
111
-
-
31744451535
-
Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
-
Svard J., Heby-Henricson K., Persson-Lek M., Rozell B., Lauth M., Bergstrom A., Ericson J., Toftgard R., and Teglund S. Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway. Dev. Cell 10 (2006) 187-197
-
(2006)
Dev. Cell
, vol.10
, pp. 187-197
-
-
Svard, J.1
Heby-Henricson, K.2
Persson-Lek, M.3
Rozell, B.4
Lauth, M.5
Bergstrom, A.6
Ericson, J.7
Toftgard, R.8
Teglund, S.9
-
112
-
-
26244435498
-
Molecular pathology of ataxia telangiectasia
-
Taylor A.M.R., and Byrd P.J. Molecular pathology of ataxia telangiectasia. J. Clin. Pathol. 58 (2005) 1009-1015
-
(2005)
J. Clin. Pathol.
, vol.58
, pp. 1009-1015
-
-
Taylor, A.M.R.1
Byrd, P.J.2
-
113
-
-
26644435531
-
Radial glia cells are candidate stem cells of ependymoma
-
Taylor M.D., Poppleton H., Fuller C., Su X., Liu Y., Jensen P., Magdaleno S., Dalton J., Calabrese C., Board J., Macdonald T., Rutka J., Guha A., Gajjar A., Curran T., and Gilbertson R.J. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 8 (2005) 323-335
-
(2005)
Cancer Cell
, vol.8
, pp. 323-335
-
-
Taylor, M.D.1
Poppleton, H.2
Fuller, C.3
Su, X.4
Liu, Y.5
Jensen, P.6
Magdaleno, S.7
Dalton, J.8
Calabrese, C.9
Board, J.10
Macdonald, T.11
Rutka, J.12
Guha, A.13
Gajjar, A.14
Curran, T.15
Gilbertson, R.J.16
-
114
-
-
0035499887
-
The development of neural stem cells
-
Temple S. The development of neural stem cells. Nature 414 (2001) 112-117
-
(2001)
Nature
, vol.414
, pp. 112-117
-
-
Temple, S.1
-
115
-
-
1642445643
-
Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon
-
Tropepe V., Sibilia M., Ciruna B.G., Rossant J., Wagner E.F., and van der Kooy D. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Dev. Biol. 208 (1999) 166-188
-
(1999)
Dev. Biol.
, vol.208
, pp. 166-188
-
-
Tropepe, V.1
Sibilia, M.2
Ciruna, B.G.3
Rossant, J.4
Wagner, E.F.5
van der Kooy, D.6
-
116
-
-
13644260101
-
Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma
-
Tunici P., Bissola L., Lualdi E., Pollo B., Cajola L., Broggi G., Sozzi G., and Finocchiaro G. Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma. Mol. Cancer 3 (2004) 25
-
(2004)
Mol. Cancer
, vol.3
, pp. 25
-
-
Tunici, P.1
Bissola, L.2
Lualdi, E.3
Pollo, B.4
Cajola, L.5
Broggi, G.6
Sozzi, G.7
Finocchiaro, G.8
-
117
-
-
0034687840
-
Direct isolation of human central nervous system stem cells
-
Uchida N., Buck D.W., He D., Reitsma M.J., Masek M., Phan T.V., Tsukamoto A.S., Gage F.H., and Weissman I.L. Direct isolation of human central nervous system stem cells. Proc. Natl. Acad Sci. U. S. A. 97 (2000) 14720-14725
-
(2000)
Proc. Natl. Acad Sci. U. S. A.
, vol.97
, pp. 14720-14725
-
-
Uchida, N.1
Buck, D.W.2
He, D.3
Reitsma, M.J.4
Masek, M.5
Phan, T.V.6
Tsukamoto, A.S.7
Gage, F.H.8
Weissman, I.L.9
-
118
-
-
0036791177
-
Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.
-
Uhrbom L., Dai C., Celestino J.C., Rosenblum M.K., Fuller G.N., and Holland E.C. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt. Cancer Res. 62 (2002) 5551-5558
-
(2002)
Cancer Res.
, vol.62
, pp. 5551-5558
-
-
Uhrbom, L.1
Dai, C.2
Celestino, J.C.3
Rosenblum, M.K.4
Fuller, G.N.5
Holland, E.C.6
-
119
-
-
27744450224
-
The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation
-
Uziel T., Zindy F., Xie S., Lee Y., Forget A., Magdaleno S., Rehg J.E., Calabrese C., Solecki D., Eberhart C.G., Sherr S.E., Plimmer S., Clifford S.C., Hatten M.E., McKinnon P.J., Gilbertson R.J., Curran T., Sherr C.J., and Roussel M.F. The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation. Genes Dev. 19 (2005) 2656-2667
-
(2005)
Genes Dev.
, vol.19
, pp. 2656-2667
-
-
Uziel, T.1
Zindy, F.2
Xie, S.3
Lee, Y.4
Forget, A.5
Magdaleno, S.6
Rehg, J.E.7
Calabrese, C.8
Solecki, D.9
Eberhart, C.G.10
Sherr, S.E.11
Plimmer, S.12
Clifford, S.C.13
Hatten, M.E.14
McKinnon, P.J.15
Gilbertson, R.J.16
Curran, T.17
Sherr, C.J.18
Roussel, M.F.19
-
121
-
-
20544460148
-
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
van Es J.H., van Gijn M.E., Riccio O., van den Born M., Vooijs M., Begthel H., Cozijnsen M., Robine S., Winton D.J., Radtke F., and Clevers H. Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435 (2005) 959-963
-
(2005)
Nature
, vol.435
, pp. 959-963
-
-
van Es, J.H.1
van Gijn, M.E.2
Riccio, O.3
van den Born, M.4
Vooijs, M.5
Begthel, H.6
Cozijnsen, M.7
Robine, S.8
Winton, D.J.9
Radtke, F.10
Clevers, H.11
-
122
-
-
31744436876
-
Divergence of hedgehog signal transduction mechanism between Drosophila and mammals
-
Varjosalo M., Li S.P., and Taipale J. Divergence of hedgehog signal transduction mechanism between Drosophila and mammals. Dev. Cell 10 (2006) 177-186
-
(2006)
Dev. Cell
, vol.10
, pp. 177-186
-
-
Varjosalo, M.1
Li, S.P.2
Taipale, J.3
-
124
-
-
8644240036
-
Distinct neural precursors in the developing human spinal cord
-
Walder S., and Ferretti P. Distinct neural precursors in the developing human spinal cord. Int. J. Dev. Biol. 48 (2004) 671-674
-
(2004)
Int. J. Dev. Biol.
, vol.48
, pp. 671-674
-
-
Walder, S.1
Ferretti, P.2
-
125
-
-
0029860591
-
Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis
-
Weiss S., Dunne C., Hewson J., Wohl C., Wheatley M., Peterson A.C., and Reynolds B.A. Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis. J. Neurosci. 16 (1996) 7599-7609
-
(1996)
J. Neurosci.
, vol.16
, pp. 7599-7609
-
-
Weiss, S.1
Dunne, C.2
Hewson, J.3
Wohl, C.4
Wheatley, M.5
Peterson, A.C.6
Reynolds, B.A.7
-
126
-
-
0037421896
-
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing
-
Wong K.K., Maser R.S., Bachoo R.M., Menon J., Carrasco D.R., Gu Y., Alt F.W., and DePinho R.A. Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing. Nature 421 (2003) 643-648
-
(2003)
Nature
, vol.421
, pp. 643-648
-
-
Wong, K.K.1
Maser, R.S.2
Bachoo, R.M.3
Menon, J.4
Carrasco, D.R.5
Gu, Y.6
Alt, F.W.7
DePinho, R.A.8
-
127
-
-
0034161886
-
WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene
-
Xu L., Corcoran R.B., Welsh J.W., Pennica D., and Levine A.J. WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene. Genes Dev. 14 (2000) 585-595
-
(2000)
Genes Dev.
, vol.14
, pp. 585-595
-
-
Xu, L.1
Corcoran, R.B.2
Welsh, J.W.3
Pennica, D.4
Levine, A.J.5
-
128
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
Yilmaz O.H., Valdez R., Theisen B.K., Guo W., Ferguson D.O., Wu H., and Morrison S.J. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441 (2006) 475-482
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
Morrison, S.J.7
-
129
-
-
0034044574
-
Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells
-
Zappone M.V., Galli R., Catena R., Meani N., De Biasi S., Mattei E., Tiveron C., Vescovi A.L., Lovell-Badge R., Ottolenghi S., and Nicolis S.K. Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells. Development 127 (2000) 2367-2382
-
(2000)
Development
, vol.127
, pp. 2367-2382
-
-
Zappone, M.V.1
Galli, R.2
Catena, R.3
Meani, N.4
De Biasi, S.5
Mattei, E.6
Tiveron, C.7
Vescovi, A.L.8
Lovell-Badge, R.9
Ottolenghi, S.10
Nicolis, S.K.11
-
130
-
-
0038517899
-
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system
-
Zechner D., Fujita Y., Hulsken J., Muller T., Walther I., Taketo M.M., Crenshaw III E.B., Birchmeier W., and Birchmeier C. beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. Dev. Biol. 258 (2003) 406-418
-
(2003)
Dev. Biol.
, vol.258
, pp. 406-418
-
-
Zechner, D.1
Fujita, Y.2
Hulsken, J.3
Muller, T.4
Walther, I.5
Taketo, M.M.6
Crenshaw III, E.B.7
Birchmeier, W.8
Birchmeier, C.9
-
131
-
-
33646351002
-
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
-
Zhang J., Grindley J.C., Yin T., Jayasinghe S., He X.C., Ross J.T., Haug J.S., Rupp D., Porter-Westpfahl K.S., Wiedemann L.M., Wu H., and Li L. PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature 441 (2006) 518-522
-
(2006)
Nature
, vol.441
, pp. 518-522
-
-
Zhang, J.1
Grindley, J.C.2
Yin, T.3
Jayasinghe, S.4
He, X.C.5
Ross, J.T.6
Haug, J.S.7
Rupp, D.8
Porter-Westpfahl, K.S.9
Wiedemann, L.M.10
Wu, H.11
Li, L.12
-
132
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
Zhou S., Schuetz J.D., Bunting K.D., Colapietro A.M., Sampath J., Morris J.J., Lagutina I., Grosveld G.C., Osawa M., Nakauchi H., and Sorrentino B.P. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat. Med. 7 (2001) 1028-1034
-
(2001)
Nat. Med.
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
Colapietro, A.M.4
Sampath, J.5
Morris, J.J.6
Lagutina, I.7
Grosveld, G.C.8
Osawa, M.9
Nakauchi, H.10
Sorrentino, B.P.11
-
133
-
-
23644443053
-
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
-
Zhu Y., Guignard F., Zhao D., Liu L., Burns D.K., Mason R.P., Messing A., and Parada L.F. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell 8 (2005) 119-130
-
(2005)
Cancer Cell
, vol.8
, pp. 119-130
-
-
Zhu, Y.1
Guignard, F.2
Zhao, D.3
Liu, L.4
Burns, D.K.5
Mason, R.P.6
Messing, A.7
Parada, L.F.8
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