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Volumn 25, Issue 2, 2007, Pages 217-229

Cancer stem cells and "stemness" genes in neuro-oncology

Author keywords

[No Author keywords available]

Indexed keywords

SONIC HEDGEHOG PROTEIN; WNT PROTEIN;

EID: 33846330973     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2006.08.022     Document Type: Review
Times cited : (110)

References (133)
  • 1
    • 27144487469 scopus 로고    scopus 로고
    • In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog
    • Ahn S., and Joyner A.L. In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog. Nature 437 (2005) 894-897
    • (2005) Nature , vol.437 , pp. 894-897
    • Ahn, S.1    Joyner, A.L.2
  • 2
    • 0036096542 scopus 로고    scopus 로고
    • Identification of neural stem cells in the adult vertebrate brain
    • Alvarez-Buylla A., Seri B., and Doetsch F. Identification of neural stem cells in the adult vertebrate brain. Brain Res. Bull. 57 (2002) 751-758
    • (2002) Brain Res. Bull. , vol.57 , pp. 751-758
    • Alvarez-Buylla, A.1    Seri, B.2    Doetsch, F.3
  • 4
    • 1842527386 scopus 로고    scopus 로고
    • Radial glia serve as neuronal progenitors in all regions of the central nervous system
    • Anthony T.E., Klein C., Fishell G., and Heintz N. Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron 41 (2004) 881-890
    • (2004) Neuron , vol.41 , pp. 881-890
    • Anthony, T.E.1    Klein, C.2    Fishell, G.3    Heintz, N.4
  • 8
    • 2442535265 scopus 로고    scopus 로고
    • Review of the prognostic factors in medulloblastoma of children and adults
    • Brandes A.A., and Paris M.K. Review of the prognostic factors in medulloblastoma of children and adults. Crit. Rev. Oncol./Hematol. 50 (2004) 121
    • (2004) Crit. Rev. Oncol./Hematol. , vol.50 , pp. 121
    • Brandes, A.A.1    Paris, M.K.2
  • 10
    • 0242353154 scopus 로고    scopus 로고
    • Vertebrate neurogenesis is counteracted by Sox1-3 activity
    • Bylund M., Andersson E., Novitch B.G., and Muhr J. Vertebrate neurogenesis is counteracted by Sox1-3 activity. Nat. Neurosci. 6 (2003) 1162-1168
    • (2003) Nat. Neurosci. , vol.6 , pp. 1162-1168
    • Bylund, M.1    Andersson, E.2    Novitch, B.G.3    Muhr, J.4
  • 11
    • 0037194887 scopus 로고    scopus 로고
    • LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal
    • Capela A., and Temple S. LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. Neuron 35 (2002) 865-875
    • (2002) Neuron , vol.35 , pp. 865-875
    • Capela, A.1    Temple, S.2
  • 13
    • 0037135177 scopus 로고    scopus 로고
    • Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
    • Chenn A., and Walsh C.A. Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science 297 (2002) 365-369
    • (2002) Science , vol.297 , pp. 365-369
    • Chenn, A.1    Walsh, C.A.2
  • 14
    • 33646045010 scopus 로고    scopus 로고
    • Stem cells and cancer: two faces of eve
    • Clarke M.F., and Fuller M. Stem cells and cancer: two faces of eve. Cell 124 (2006) 1111-1115
    • (2006) Cell , vol.124 , pp. 1111-1115
    • Clarke, M.F.1    Fuller, M.2
  • 15
    • 10344248682 scopus 로고    scopus 로고
    • Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development
    • Corrales J.D., Rocco G.L., Blaess S., Guo Q., and Joyner A.L. Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development 131 (2004) 5581-5590
    • (2004) Development , vol.131 , pp. 5581-5590
    • Corrales, J.D.1    Rocco, G.L.2    Blaess, S.3    Guo, Q.4    Joyner, A.L.5
  • 16
    • 0035425048 scopus 로고    scopus 로고
    • PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo
    • Dai C., Celestino J.C., Okada Y., Louis D.N., Fuller G.N., and Holland E.C. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev. 15 (2001) 1913-1925
    • (2001) Genes Dev. , vol.15 , pp. 1913-1925
    • Dai, C.1    Celestino, J.C.2    Okada, Y.3    Louis, D.N.4    Fuller, G.N.5    Holland, E.C.6
  • 17
    • 18644373850 scopus 로고    scopus 로고
    • The characteristics of astrocytomas and oligodendrogliomas are caused by two distinct and interchangeable signaling formats
    • Dai C., Lyustikman Y., Shih A., Hu X., Fuller G.N., Rosenblum M., and Holland E.C. The characteristics of astrocytomas and oligodendrogliomas are caused by two distinct and interchangeable signaling formats. Neoplasia 7 (2005) 397-406
    • (2005) Neoplasia , vol.7 , pp. 397-406
    • Dai, C.1    Lyustikman, Y.2    Shih, A.3    Hu, X.4    Fuller, G.N.5    Rosenblum, M.6    Holland, E.C.7
  • 18
    • 0027941902 scopus 로고
    • A self-renewing multipotential stem cell in embryonic rat cerebral cortex
    • Davis A.A., and Temple S. A self-renewing multipotential stem cell in embryonic rat cerebral cortex. Nature 372 (1994) 263-266
    • (1994) Nature , vol.372 , pp. 263-266
    • Davis, A.A.1    Temple, S.2
  • 19
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • Di Cristofano A., and Pandolfi P.P. The multiple roles of PTEN in tumor suppression. Cell 100 (2000) 387-390
    • (2000) Cell , vol.100 , pp. 387-390
    • Di Cristofano, A.1    Pandolfi, P.P.2
  • 20
    • 0038011863 scopus 로고    scopus 로고
    • Stem cells: self-renewal writ in blood
    • Dick J.E. Stem cells: self-renewal writ in blood. Nature 423 (2003) 231-233
    • (2003) Nature , vol.423 , pp. 231-233
    • Dick, J.E.1
  • 21
    • 0242321829 scopus 로고    scopus 로고
    • The glial identity of neural stem cells
    • Doetsch F. The glial identity of neural stem cells. Nat. Neurosci. 6 (2003) 1127-1134
    • (2003) Nat. Neurosci. , vol.6 , pp. 1127-1134
    • Doetsch, F.1
  • 22
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • Doetsch F., Caille I., Lim D.A., Garcia-Verdugo J.M., and Alvarez-Buylla A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97 (1999) 703-716
    • (1999) Cell , vol.97 , pp. 703-716
    • Doetsch, F.1    Caille, I.2    Lim, D.A.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 23
    • 0037137686 scopus 로고    scopus 로고
    • EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells
    • Doetsch F., Petreanu L., Caille I., Garcia-Verdugo J.M., and Alvarez-Buylla A. EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron 36 (2002) 1021-1034
    • (2002) Neuron , vol.36 , pp. 1021-1034
    • Doetsch, F.1    Petreanu, L.2    Caille, I.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 28
    • 0344256592 scopus 로고    scopus 로고
    • Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro
    • Gabay L., Lowell S., Rubin L.L., and Anderson D.J. Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Neuron 40 (2003) 485-499
    • (2003) Neuron , vol.40 , pp. 485-499
    • Gabay, L.1    Lowell, S.2    Rubin, L.L.3    Anderson, D.J.4
  • 30
    • 0030866154 scopus 로고    scopus 로고
    • Altered neural cell fates and medulloblastoma in mouse patched mutants
    • Goodrich L.V., Milenkovic L., Higgins K.M., and Scott M.P. Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277 (1997) 1109-1113
    • (1997) Science , vol.277 , pp. 1109-1113
    • Goodrich, L.V.1    Milenkovic, L.2    Higgins, K.M.3    Scott, M.P.4
  • 31
    • 33747339465 scopus 로고    scopus 로고
    • Wnt signaling: multiple pathways, multiple receptors and multiple transcription factors
    • Gordon M.D., and Nusse R. Wnt signaling: multiple pathways, multiple receptors and multiple transcription factors. J Biol Chem 281 (2006) 22429-22433
    • (2006) J Biol Chem , vol.281 , pp. 22429-22433
    • Gordon, M.D.1    Nusse, R.2
  • 32
    • 0041880122 scopus 로고    scopus 로고
    • SOX2 functions to maintain neural progenitor identity
    • Graham V., Khudyakov J., Ellis P., and Pevny L. SOX2 functions to maintain neural progenitor identity. Neuron 39 (2003) 749-765
    • (2003) Neuron , vol.39 , pp. 749-765
    • Graham, V.1    Khudyakov, J.2    Ellis, P.3    Pevny, L.4
  • 35
    • 26944459216 scopus 로고    scopus 로고
    • Molecular regulation of adult CNS neurogenesis: an integrated view
    • Hagg T. Molecular regulation of adult CNS neurogenesis: an integrated view. Trends Neurosci 28 (2005) 589-595
    • (2005) Trends Neurosci , vol.28 , pp. 589-595
    • Hagg, T.1
  • 38
    • 0037206890 scopus 로고    scopus 로고
    • N-CoR controls differentiation of neural stem cells into astrocytes
    • Hermanson O., Jepsen K., and Rosenfeld M.G. N-CoR controls differentiation of neural stem cells into astrocytes. Nature 419 (2002) 934-939
    • (2002) Nature , vol.419 , pp. 934-939
    • Hermanson, O.1    Jepsen, K.2    Rosenfeld, M.G.3
  • 40
    • 0036336528 scopus 로고    scopus 로고
    • Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain
    • Hitoshi S., Tropepe V., Ekker M., and van der Kooy D. Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain. Development 129 (2002) 233-244
    • (2002) Development , vol.129 , pp. 233-244
    • Hitoshi, S.1    Tropepe, V.2    Ekker, M.3    van der Kooy, D.4
  • 41
    • 3543086157 scopus 로고    scopus 로고
    • Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling
    • Hitoshi S., Seaberg R.M., Koscik C., Alexson T., Kusunoki S., Kanazawa I., Tsuji S., and van der Kooy D. Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling. Genes Dev. 18 (2004) 1806-1811
    • (2004) Genes Dev. , vol.18 , pp. 1806-1811
    • Hitoshi, S.1    Seaberg, R.M.2    Koscik, C.3    Alexson, T.4    Kusunoki, S.5    Kanazawa, I.6    Tsuji, S.7    van der Kooy, D.8
  • 42
    • 0034612289 scopus 로고    scopus 로고
    • Glioblastoma multiforme: the terminator
    • Holland E.C. Glioblastoma multiforme: the terminator. Proc. Natl. Acad Sci. U. S. A. 97 (2000) 6242-6244
    • (2000) Proc. Natl. Acad Sci. U. S. A. , vol.97 , pp. 6242-6244
    • Holland, E.C.1
  • 43
    • 0036737914 scopus 로고    scopus 로고
    • Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
    • Ignatova T.N., Kukekov V.G., Laywell E.D., Suslov O.N., Vrionis F.D., and Steindler D.A. Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia 39 (2002) 193-206
    • (2002) Glia , vol.39 , pp. 193-206
    • Ignatova, T.N.1    Kukekov, V.G.2    Laywell, E.D.3    Suslov, O.N.4    Vrionis, F.D.5    Steindler, D.A.6
  • 45
    • 33745880884 scopus 로고    scopus 로고
    • PDGFRalpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling
    • Jackson E.L., Garcia-Verdugo J.M., Gil-Perotin S., Roy M., Quinones-Hinojosa A., Vandenberg S., and Alvarez-Buylla A. PDGFRalpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling. Neuron 51 (2006) 187-199
    • (2006) Neuron , vol.51 , pp. 187-199
    • Jackson, E.L.1    Garcia-Verdugo, J.M.2    Gil-Perotin, S.3    Roy, M.4    Quinones-Hinojosa, A.5    Vandenberg, S.6    Alvarez-Buylla, A.7
  • 46
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • Jacobs J.J., Kieboom K., Marino S., DePinho R.A., and van Lohuizen M. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397 (1999) 164-168
    • (1999) Nature , vol.397 , pp. 164-168
    • Jacobs, J.J.1    Kieboom, K.2    Marino, S.3    DePinho, R.A.4    van Lohuizen, M.5
  • 47
    • 33745321352 scopus 로고    scopus 로고
    • Stem cells: good, bad and reformable
    • Janzen V., and Scadden D.T. Stem cells: good, bad and reformable. Nature 441 (2006) 418-419
    • (2006) Nature , vol.441 , pp. 418-419
    • Janzen, V.1    Scadden, D.T.2
  • 49
    • 0037232580 scopus 로고    scopus 로고
    • Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
    • Kenney A.M., Cole M.D., and Rowitch D.H. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development 130 (2003) 15-28
    • (2003) Development , vol.130 , pp. 15-28
    • Kenney, A.M.1    Cole, M.D.2    Rowitch, D.H.3
  • 50
    • 20444433526 scopus 로고    scopus 로고
    • Gli1 is important for medulloblastoma formation in Ptc1+/- mice
    • Kimura H., Stephen D., Joyner A., and Curran T. Gli1 is important for medulloblastoma formation in Ptc1+/- mice. Oncogene 24 (2005) 4026-4036
    • (2005) Oncogene , vol.24 , pp. 4026-4036
    • Kimura, H.1    Stephen, D.2    Joyner, A.3    Curran, T.4
  • 51
    • 15444377643 scopus 로고    scopus 로고
    • p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity
    • Kippin T.E., Martens D.J., and van der Kooy D. p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity. Genes Dev. 19 (2005) 756-767
    • (2005) Genes Dev. , vol.19 , pp. 756-767
    • Kippin, T.E.1    Martens, D.J.2    van der Kooy, D.3
  • 52
    • 27744521637 scopus 로고    scopus 로고
    • Cerebellum- and forebrain-derived stem cells possess intrinsic regional character
    • Klein C., Butt S.J., Machold R.P., Johnson J.E., and Fishell G. Cerebellum- and forebrain-derived stem cells possess intrinsic regional character. Development 132 (2005) 4497-4508
    • (2005) Development , vol.132 , pp. 4497-4508
    • Klein, C.1    Butt, S.J.2    Machold, R.P.3    Johnson, J.E.4    Fishell, G.5
  • 53
    • 0037108268 scopus 로고    scopus 로고
    • N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
    • Knoepfler P.S., Cheng P.F., and Eisenman R.N. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev. 16 (2002) 2699-2712
    • (2002) Genes Dev. , vol.16 , pp. 2699-2712
    • Knoepfler, P.S.1    Cheng, P.F.2    Eisenman, R.N.3
  • 54
    • 0034622930 scopus 로고    scopus 로고
    • Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells
    • Kondo T., and Raff M. Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells. Science 289 (2000) 1754-1757
    • (2000) Science , vol.289 , pp. 1754-1757
    • Kondo, T.1    Raff, M.2
  • 55
    • 9944266165 scopus 로고    scopus 로고
    • Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells
    • Kondo T., and Raff M. Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells. Genes Dev. 18 (2004) 2963-2972
    • (2004) Genes Dev. , vol.18 , pp. 2963-2972
    • Kondo, T.1    Raff, M.2
  • 56
    • 1642474273 scopus 로고    scopus 로고
    • Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
    • Kondo T., Setoguchi T., and Taga T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc. Natl. Acad Sci. U. S. A. 101 (2004) 781-786
    • (2004) Proc. Natl. Acad Sci. U. S. A. , vol.101 , pp. 781-786
    • Kondo, T.1    Setoguchi, T.2    Taga, T.3
  • 57
    • 0037218819 scopus 로고    scopus 로고
    • Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
    • Lai K., Kaspar B.K., Gage F.H., and Schaffer D.V. Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat. Neurosci. 6 (2003) 21-27
    • (2003) Nat. Neurosci. , vol.6 , pp. 21-27
    • Lai, K.1    Kaspar, B.K.2    Gage, F.H.3    Schaffer, D.V.4
  • 59
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J., and Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423 (2003) 255-260
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 61
    • 33646358694 scopus 로고    scopus 로고
    • Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
    • Lee J., Kotliarova S., Kotliarov Y., Li A., Su Q., Donin N.M., Pastorino S., Purow B.W., Christopher N., Zhang W., Park J.K., and Fine H.A. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 9 (2006) 391-403
    • (2006) Cancer Cell , vol.9 , pp. 391-403
    • Lee, J.1    Kotliarova, S.2    Kotliarov, Y.3    Li, A.4    Su, Q.5    Donin, N.M.6    Pastorino, S.7    Purow, B.W.8    Christopher, N.9    Zhang, W.10    Park, J.K.11    Fine, H.A.12
  • 62
    • 0346732391 scopus 로고    scopus 로고
    • Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis
    • Li H.S., Wang D., Shen Q., Schonemann M.D., Gorski J.A., Jones K.R., Temple S., Jan L.Y., and Jan Y.N. Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron 40 (2003) 1105-1118
    • (2003) Neuron , vol.40 , pp. 1105-1118
    • Li, H.S.1    Wang, D.2    Shen, Q.3    Schonemann, M.D.4    Gorski, J.A.5    Jones, K.R.6    Temple, S.7    Jan, L.Y.8    Jan, Y.N.9
  • 66
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan C.Y., and Nusse R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20 (2004) 781-810
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 67
    • 25644435002 scopus 로고    scopus 로고
    • Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors
    • Machold R., and Fishell G. Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors. Neuron 48 (2005) 17-24
    • (2005) Neuron , vol.48 , pp. 17-24
    • Machold, R.1    Fishell, G.2
  • 69
    • 0034518641 scopus 로고    scopus 로고
    • Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage
    • Malatesta P., Hartfuss E., and Gotz M. Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage. Development 127 (2000) 5253-5263
    • (2000) Development , vol.127 , pp. 5253-5263
    • Malatesta, P.1    Hartfuss, E.2    Gotz, M.3
  • 71
    • 11844301282 scopus 로고    scopus 로고
    • Medulloblastoma: developmental mechanisms out of control
    • Marino S. Medulloblastoma: developmental mechanisms out of control. Trends Mol. Med. 11 (2005) 17-22
    • (2005) Trends Mol. Med. , vol.11 , pp. 17-22
    • Marino, S.1
  • 72
    • 9244239811 scopus 로고    scopus 로고
    • G1 cell-cycle control and cancer
    • Massague J. G1 cell-cycle control and cancer. Nature 432 (2004) 298
    • (2004) Nature , vol.432 , pp. 298
    • Massague, J.1
  • 73
    • 0030894092 scopus 로고    scopus 로고
    • Stem cells in the central nervous system
    • McKay R. Stem cells in the central nervous system. Science 276 (1997) 66-71
    • (1997) Science , vol.276 , pp. 66-71
    • McKay, R.1
  • 76
    • 5044224775 scopus 로고    scopus 로고
    • DNA-microarray analysis of brain cancer: molecular classification for therapy
    • Mischel P.S., Cloughesy T.F., and Nelson S.F. DNA-microarray analysis of brain cancer: molecular classification for therapy. Nat. Rev., Neurosci. 5 (2004) 782-792
    • (2004) Nat. Rev., Neurosci. , vol.5 , pp. 782-792
    • Mischel, P.S.1    Cloughesy, T.F.2    Nelson, S.F.3
  • 77
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky A.V., Pardal R., Iwashita T., Park I.K., Clarke M.F., and Morrison S.J. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425 (2003) 962-967
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 78
    • 22344449361 scopus 로고    scopus 로고
    • Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
    • Molofsky A.V., He S., Bydon M., Morrison S.J., and Pardal R. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev. 19 (2005) 1432-1437
    • (2005) Genes Dev. , vol.19 , pp. 1432-1437
    • Molofsky, A.V.1    He, S.2    Bydon, M.3    Morrison, S.J.4    Pardal, R.5
  • 79
    • 0035825670 scopus 로고    scopus 로고
    • Neurons derived from radial glial cells establish radial units in neocortex
    • Noctor S.C., Flint A.C., Weissman T.A., Dammerman R.S., and Kriegstein A.R. Neurons derived from radial glial cells establish radial units in neocortex. Nature 409 (2001) 714-720
    • (2001) Nature , vol.409 , pp. 714-720
    • Noctor, S.C.1    Flint, A.C.2    Weissman, T.A.3    Dammerman, R.S.4    Kriegstein, A.R.5
  • 80
    • 16444368462 scopus 로고    scopus 로고
    • Genetic pathways to glioblastomas
    • Ohgaki H. Genetic pathways to glioblastomas. Neuropathology 25 (2005) 1-7
    • (2005) Neuropathology , vol.25 , pp. 1-7
    • Ohgaki, H.1
  • 81
    • 2942700004 scopus 로고    scopus 로고
    • Getting at the root and stem of brain tumors
    • Oliver T.G., and Wechsler-Reya R.J. Getting at the root and stem of brain tumors. Neuron 42 (2004) 885-888
    • (2004) Neuron , vol.42 , pp. 885-888
    • Oliver, T.G.1    Wechsler-Reya, R.J.2
  • 83
    • 0031797679 scopus 로고    scopus 로고
    • Plasticity and stem cells in the vertebrate nervous system
    • Panchision D., Hazel T., and McKay R. Plasticity and stem cells in the vertebrate nervous system. Curr. Opin. Cell Biol. 10 (1998) 727-733
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 727-733
    • Panchision, D.1    Hazel, T.2    McKay, R.3
  • 84
    • 0345059767 scopus 로고    scopus 로고
    • Applying the principles of stem-cell biology to cancer
    • Pardal R., Clarke M.F., and Morrison S.J. Applying the principles of stem-cell biology to cancer. Nat. Rev., Cancer 3 (2003) 895-902
    • (2003) Nat. Rev., Cancer , vol.3 , pp. 895-902
    • Pardal, R.1    Clarke, M.F.2    Morrison, S.J.3
  • 85
  • 87
    • 0141483064 scopus 로고    scopus 로고
    • Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
    • Passegue E., Jamieson C.H., Ailles L.E., and Weissman I.L. Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?. Proc. Natl. Acad Sci. U. S. A. 100 Suppl 1 (2003) 11842-11849
    • (2003) Proc. Natl. Acad Sci. U. S. A. , vol.100 , Issue.SUPPL. 1 , pp. 11842-11849
    • Passegue, E.1    Jamieson, C.H.2    Ailles, L.E.3    Weissman, I.L.4
  • 88
    • 7044269527 scopus 로고    scopus 로고
    • JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells
    • Passegue E., Wagner E.F., and Weissman I.L. JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell 119 (2004) 431-443
    • (2004) Cell , vol.119 , pp. 431-443
    • Passegue, E.1    Wagner, E.F.2    Weissman, I.L.3
  • 89
    • 0037206889 scopus 로고    scopus 로고
    • Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
    • Petersen P.H., Zou K., Hwang J.K., Jan Y.N., and Zhong W. Progenitor cell maintenance requires numb and numblike during mouse neurogenesis. Nature 419 (2002) 929-934
    • (2002) Nature , vol.419 , pp. 929-934
    • Petersen, P.H.1    Zou, K.2    Hwang, J.K.3    Jan, Y.N.4    Zhong, W.5
  • 90
    • 3342938070 scopus 로고    scopus 로고
    • Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis
    • Petersen P.H., Zou K., Krauss S., and Zhong W. Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat. Neurosci. 7 (2004) 803-811
    • (2004) Nat. Neurosci. , vol.7 , pp. 803-811
    • Petersen, P.H.1    Zou, K.2    Krauss, S.3    Zhong, W.4
  • 92
    • 0031688990 scopus 로고    scopus 로고
    • Intrinsic programs of patterned cell lineages in isolated vertebrate CNS ventricular zone cells
    • Qian X., Goderie S.K., Shen Q., Stern J.H., and Temple S. Intrinsic programs of patterned cell lineages in isolated vertebrate CNS ventricular zone cells. Development 125 (1998) 3143-3152
    • (1998) Development , vol.125 , pp. 3143-3152
    • Qian, X.1    Goderie, S.K.2    Shen, Q.3    Stern, J.H.4    Temple, S.5
  • 93
    • 0033636521 scopus 로고    scopus 로고
    • Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells
    • Qian X., Shen Q., Goderie S.K., He W., Capela A., Davis A.A., and Temple S. Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells. Neuron 28 (2000) 69-80
    • (2000) Neuron , vol.28 , pp. 69-80
    • Qian, X.1    Shen, Q.2    Goderie, S.K.3    He, W.4    Capela, A.5    Davis, A.A.6    Temple, S.7
  • 94
    • 0037902082 scopus 로고    scopus 로고
    • c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice
    • Rao G., Pedone C.A., Coffin C.M., Holland E.C., and Fults D.W. c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice. Neoplasia 5 (2003) 198-204
    • (2003) Neoplasia , vol.5 , pp. 198-204
    • Rao, G.1    Pedone, C.A.2    Coffin, C.M.3    Holland, E.C.4    Fults, D.W.5
  • 95
    • 4444273153 scopus 로고    scopus 로고
    • Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice
    • Rao G., Pedone C.A., Valle L.D., Reiss K., Holland E.C., and Fults D.W. Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice. Oncogene 23 (2004) 6156-6162
    • (2004) Oncogene , vol.23 , pp. 6156-6162
    • Rao, G.1    Pedone, C.A.2    Valle, L.D.3    Reiss, K.4    Holland, E.C.5    Fults, D.W.6
  • 96
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya T., and Clevers H. Wnt signalling in stem cells and cancer. Nature 434 (2005) 843-850
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 98
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds B.A., and Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255 (1992) 1707-1710
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 100
    • 4043147087 scopus 로고    scopus 로고
    • Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling
    • Rios I., Alvarez-Rodriguez R., Marti E., and Pons S. Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling. Development 131 (2004) 3159-3168
    • (2004) Development , vol.131 , pp. 3159-3168
    • Rios, I.1    Alvarez-Rodriguez, R.2    Marti, E.3    Pons, S.4
  • 102
    • 0036559186 scopus 로고    scopus 로고
    • Gli and hedgehog in cancer: tumours, embryos and stem cells
    • Ruiz i Altaba A., Sanchez P., and Dahmane N. Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat. Rev., Cancer 2 (2002) 361-372
    • (2002) Nat. Rev., Cancer , vol.2 , pp. 361-372
    • Ruiz i Altaba, A.1    Sanchez, P.2    Dahmane, N.3
  • 103
    • 5644266355 scopus 로고    scopus 로고
    • Expression of MATH1, a marker of cerebellar granule cell progenitors, identifies different medulloblastoma sub-types
    • Salsano E., Pollo B., Eoli M., Giordana M.T., and Finocchiaro G. Expression of MATH1, a marker of cerebellar granule cell progenitors, identifies different medulloblastoma sub-types. Neurosci. Lett. 370 (2004) 180-185
    • (2004) Neurosci. Lett. , vol.370 , pp. 180-185
    • Salsano, E.1    Pollo, B.2    Eoli, M.3    Giordana, M.T.4    Finocchiaro, G.5
  • 109
    • 6044221204 scopus 로고    scopus 로고
    • Cancer stem cells in nervous system tumors
    • Singh S.K., Clarke I.D., Hide T., and Dirks P.B. Cancer stem cells in nervous system tumors. Oncogene 23 (2004) 7267-7273
    • (2004) Oncogene , vol.23 , pp. 7267-7273
    • Singh, S.K.1    Clarke, I.D.2    Hide, T.3    Dirks, P.B.4
  • 110
    • 0141922983 scopus 로고    scopus 로고
    • Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1
    • Smith K.S., Chanda S.K., Lingbeek M., Ross D.T., Botstein D., van Lohuizen M., and Cleary M.L. Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1. Mol. Cell 12 (2003) 393-400
    • (2003) Mol. Cell , vol.12 , pp. 393-400
    • Smith, K.S.1    Chanda, S.K.2    Lingbeek, M.3    Ross, D.T.4    Botstein, D.5    van Lohuizen, M.6    Cleary, M.L.7
  • 112
    • 26244435498 scopus 로고    scopus 로고
    • Molecular pathology of ataxia telangiectasia
    • Taylor A.M.R., and Byrd P.J. Molecular pathology of ataxia telangiectasia. J. Clin. Pathol. 58 (2005) 1009-1015
    • (2005) J. Clin. Pathol. , vol.58 , pp. 1009-1015
    • Taylor, A.M.R.1    Byrd, P.J.2
  • 114
    • 0035499887 scopus 로고    scopus 로고
    • The development of neural stem cells
    • Temple S. The development of neural stem cells. Nature 414 (2001) 112-117
    • (2001) Nature , vol.414 , pp. 112-117
    • Temple, S.1
  • 115
    • 1642445643 scopus 로고    scopus 로고
    • Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon
    • Tropepe V., Sibilia M., Ciruna B.G., Rossant J., Wagner E.F., and van der Kooy D. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Dev. Biol. 208 (1999) 166-188
    • (1999) Dev. Biol. , vol.208 , pp. 166-188
    • Tropepe, V.1    Sibilia, M.2    Ciruna, B.G.3    Rossant, J.4    Wagner, E.F.5    van der Kooy, D.6
  • 118
    • 0036791177 scopus 로고    scopus 로고
    • Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.
    • Uhrbom L., Dai C., Celestino J.C., Rosenblum M.K., Fuller G.N., and Holland E.C. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt. Cancer Res. 62 (2002) 5551-5558
    • (2002) Cancer Res. , vol.62 , pp. 5551-5558
    • Uhrbom, L.1    Dai, C.2    Celestino, J.C.3    Rosenblum, M.K.4    Fuller, G.N.5    Holland, E.C.6
  • 120
    • 4644319204 scopus 로고    scopus 로고
    • Stem cells and cancer; the polycomb connection
    • Valk-Lingbeek M.E., Bruggeman S.W., and van Lohuizen M. Stem cells and cancer; the polycomb connection. Cell 118 (2004) 409-418
    • (2004) Cell , vol.118 , pp. 409-418
    • Valk-Lingbeek, M.E.1    Bruggeman, S.W.2    van Lohuizen, M.3
  • 122
    • 31744436876 scopus 로고    scopus 로고
    • Divergence of hedgehog signal transduction mechanism between Drosophila and mammals
    • Varjosalo M., Li S.P., and Taipale J. Divergence of hedgehog signal transduction mechanism between Drosophila and mammals. Dev. Cell 10 (2006) 177-186
    • (2006) Dev. Cell , vol.10 , pp. 177-186
    • Varjosalo, M.1    Li, S.P.2    Taipale, J.3
  • 124
    • 8644240036 scopus 로고    scopus 로고
    • Distinct neural precursors in the developing human spinal cord
    • Walder S., and Ferretti P. Distinct neural precursors in the developing human spinal cord. Int. J. Dev. Biol. 48 (2004) 671-674
    • (2004) Int. J. Dev. Biol. , vol.48 , pp. 671-674
    • Walder, S.1    Ferretti, P.2
  • 125
    • 0029860591 scopus 로고    scopus 로고
    • Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis
    • Weiss S., Dunne C., Hewson J., Wohl C., Wheatley M., Peterson A.C., and Reynolds B.A. Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis. J. Neurosci. 16 (1996) 7599-7609
    • (1996) J. Neurosci. , vol.16 , pp. 7599-7609
    • Weiss, S.1    Dunne, C.2    Hewson, J.3    Wohl, C.4    Wheatley, M.5    Peterson, A.C.6    Reynolds, B.A.7
  • 126
  • 128
    • 33646376411 scopus 로고    scopus 로고
    • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
    • Yilmaz O.H., Valdez R., Theisen B.K., Guo W., Ferguson D.O., Wu H., and Morrison S.J. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441 (2006) 475-482
    • (2006) Nature , vol.441 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3    Guo, W.4    Ferguson, D.O.5    Wu, H.6    Morrison, S.J.7
  • 129
    • 0034044574 scopus 로고    scopus 로고
    • Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells
    • Zappone M.V., Galli R., Catena R., Meani N., De Biasi S., Mattei E., Tiveron C., Vescovi A.L., Lovell-Badge R., Ottolenghi S., and Nicolis S.K. Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells. Development 127 (2000) 2367-2382
    • (2000) Development , vol.127 , pp. 2367-2382
    • Zappone, M.V.1    Galli, R.2    Catena, R.3    Meani, N.4    De Biasi, S.5    Mattei, E.6    Tiveron, C.7    Vescovi, A.L.8    Lovell-Badge, R.9    Ottolenghi, S.10    Nicolis, S.K.11
  • 133
    • 23644443053 scopus 로고    scopus 로고
    • Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
    • Zhu Y., Guignard F., Zhao D., Liu L., Burns D.K., Mason R.P., Messing A., and Parada L.F. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell 8 (2005) 119-130
    • (2005) Cancer Cell , vol.8 , pp. 119-130
    • Zhu, Y.1    Guignard, F.2    Zhao, D.3    Liu, L.4    Burns, D.K.5    Mason, R.P.6    Messing, A.7    Parada, L.F.8


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