Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

Oncogene

Volumn 23, Issue 36, 2004, Pages 6156-6162

  Rao, Ganesh ^a   Pedone, Carolyn A ^a   Valle, Luis Del ^b   Reiss, Krzysztof ^b   Holland, Eric C ^c   Fults, Daniel W ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b TEMPLE UNIVERSITY   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

IGF2; Medulloblastoma; Neural progenitors; RCAS tv a; Sonic hedgehog

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 1; NESTIN; PROTEIN KINASE B; RETROVIRUS VECTOR; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL TYPE; CEREBELLUM; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENE TRANSFER; MEDULLOBLASTOMA; MOUSE; NERVE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEM CELL; UPREGULATION;

ANIMALS; CELL LINE; CEREBELLAR NEOPLASMS; CEREBELLUM; CHICKENS; GENETIC VECTORS; HEDGEHOG PROTEINS; HUMANS; INSULIN-LIKE GROWTH FACTOR II; INTERMEDIATE FILAMENT PROTEINS; MEDULLOBLASTOMA; MICE; NERVE TISSUE PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RETROVIRIDAE; SIGNAL TRANSDUCTION; STEM CELLS; TRANS-ACTIVATORS;

ANIMALIA; EPICOCCUM; ERINACEIDAE; UNIDENTIFIED RETROVIRUS;

EID: 4444273153     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207818     Document Type: Article

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