Plasticity and stem cells in the vertebrate nervous system

Current Opinion in Cell Biology

Volumn 10, Issue 6, 1998, Pages 727-733

  Panchision, David ^a   Hazel, Thomas ^a   McKay, Ron ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

ANIMAL CELL; CELL DENSITY; CELL TYPE; GENE CONTROL; HUMAN; HUMAN CELL; NERVE CELL PLASTICITY; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; REVIEW; STEM CELL;

ANIMALIA; VERTEBRATA;

EID: 0031797679     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(98)80114-2     Document Type: Article

References (75)

1. Williams BP, Price J. Evidence for multiple precursor cell types in the embryonic rat cereberal cortex. Neuron. 14:1995;1081-1088.
2. Rao MS, Mayer-Proschel M. Glial-restricted precursors are derived from multipotent neuroepithelial stem cells. Dev Biol. 188:1997;48-63.
3. Mayer-Proschel M, Kalyani AJ, Mujtaba T, Rao MS. Isolation of lineage-restricted neuronal precursors from multipotent neuroepithelial stem cells. Neuron. 19:1997;773-785.
4. Mujtaba T, Mayer-Proschel M, Rao MS. A common neural progenitor for the CNS and PNS. of special interest Dev Biol. 200:1998;1-15 BMPs are shown to induce neural crest stem cells from spinal cord stem cells in culture.
5. Johe KK, Hazel TG, Muller T, Dugich-Djordjevic MM, McKay RD. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev. 10:1996;3129-3140.
6. Qian XM, Davis AA, Goderie SK, Temple S. FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells. Neuron. 18:1997;81-93.
7. Luskin MB. Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron. 11:1993;173-189.
8. Lois C, Alvarez-Buylla A. Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia. Proc Natl Acad Sci USA. 90:1993;2074-2077.
9. Cattaneo E, McKay RDG. Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor. Nature. 347:1990;762-765.
10. Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science. 255:1992;1707-1710.
11. Davis AA, Temple S. A self-renewing multipotential stem cell in embryonic rat cerebral. Nature. 372:1994;263-266.
12. Grunz H, Tacke L. Neural differentiation of Xenopus laevis ectoderm takes place after disaggregation and delayed reaggregation without inducer. Cell Differ Dev. 28:1989;211-217.
13. Godsave SF, Slack JM. Clonal analysis of mesoderm induction in Xenopus laevis. Dev Biol. 134:1989;486-490.
14. Sato SM, Sargent TD. Development of neural inducing capacity in dissociated Xenopus embryos. Dev Biol. 134:1989;263-266.
15. Chang C, Hemmati-Brivanlou A. Cell fate determination in embryonic ectoderm. J Neurobiol. 36:1998;128-151.
16. Hsu DR, Economides AN, Wang X, Eimon PM, Harland RM. The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol Cell. 1:1998;673-683.
17. Piccolo S, Sasai Y, Lu B, De Robertis EM. Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell. 86:1996;589-598.
18. Fainsod A, Deissler K, Yelin R, Marom K, Epstein M, Pillemer G, Steinbeisser H, Blum M. The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4. Mech Dev. 63:1997;39-50.
19. Zimmerman LB, De Jesus-Escobar JM, Harland RM. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell. 86:1996;599-606.
20. Streit A, Sockanathan S, Perez L, Rex M, Scotting PJ, Sharpe PT, Lovell-Badge R, Stern CD. Preventing the loss of competence for neural induction: HGF/SF, L5 and Sox-2. of special interest Development. 124:1997;1191-1202 Proposes a model in which extrinsic signals regulate the competence of the chick epiblast to respond to neural inducing signals, and shows that HGF plays a role in generating competence for neural induction, but not in conferring regional identity.
21. Streit A, Lee KJ, Woo I, Roberts C, Jessell TM, Stern CD. Chordin regulates primitive streak development and the stability of induced neural cells, but is not sufficient for neural induction in the chick embryo. of outstanding interest Development. 125:1998;507-519 Demonstrates that repression of BMP signaling in chick mediates two distinct processes: formation of the primitive streak and later stabilization of induced neural tissue. The BMP antagonist chordin is not sufficient to initiate neural induction, which requires an unknown signal(s) from the node.
22. Ericson J, Morton S, Kawakami A, Roelink H, Jessell TM. Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity. Cell. 87:1996;661-673.
23. Dickinson ME, Selleck MA, McMahon AP, Bronner-Fraser M. Dorsalization of the neural tube by the non-neural ectoderm. Development. 121:1995;2099-2106.
24. Liem KF Jr, Tremml G, Roelink H, Jessell TM. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell. 82:1995;969-979.
25. Ye W, Shimamura K, Rubenstein JL, Hynes MA, Rosenthal A. FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. of outstanding interest Cell. 93:1998;755-766 Shows that both FGF8 and Shh are required to generate dopaminergic neurons in the ventral midbrain, supporting a Cartesian grid model for cell type generation; FGF4 ectopically generates serotonergic cells at a specific concentration, suggesting that it can act as a posteriorizing morphogen.
26. Crossley PH, Martinez S, Martin GR. Midbrain development induced by FGF8 in the chick embryo. Nature. 380:1996;66-68.
27. Lee SM, Danielian PS, Fritzsch B, McMahon AP. Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. of special interest Development. 124:1997;959-969 Provides evidence for a molecular hierarchy in which FGF8 induces genes regulating midbrain-hindbrain polarity; also suggests that part of its patterning actions may be mediated through mitogenic effects.
28. Lumsden A, Krumlauf R. Patterning the vertebrate neuraxis. Science. 274:1996;1109-1115.
29. Godsave SF, Koster CH, Getahun A, Mathu M, Hooiveld M, van der Wees J, Hendriks J, Durston AJ. Graded retinoid responses in the developing hindbrain. Dev Dyn. 213:1998;39-49.
30. Van der Wees J, Schilthuis JG, Koster CH, Diesveld-Schipper H, Folkers GE, van der Saag PT, Dawson MI, Shudo K, van der Burg B, Durston AJ. Inhibition of retinoic acid receptor-mediated signalling alters positional identity in the developing hindbrain. Development. 125:1998;545-556.
31. Blumberg B, Bolado J Jr, Moreno TA, Kintner C, Evans RM, Papalopulu N. An essential role for retinoid signaling in anteroposterior neural patterning. Development. 124:1997;373-379.
32. Foley AC, Storey KG, Stern CD. The prechordal region lacks neural inducing ability, but can confer anterior character to more posterior neuroepithelium. of special interest Development. 124:1997;2983-2996 One of several recent studies showing the importance of prechordal mesendoderm in conferring an anterior identity to neural tissue, in this case to tissue which normally generates hindbrain.
33. Millet S, Bloch-Gallego E, Simeone A, Alvarado-Mallart RM. The caudal limit of Otx2 gene expression as a marker of the midbrain/hindbrain boundary: a study using in situ hybridisation and chick/quail homotopic grafts. Development. 122:1996;3785-3797.
34. Bloch-Gallego E, Millet S, Alvarado-Mallart RM. Further observations on the susceptibility of diencephalic prosomeres to En-2 induction and on the resulting histogenetic capabilities. Mech Dev. 58:1996;51-63.
35. Martinez S, Marin F, Nieto MA, Puelles L. Induction of ectopic engrailed expression and fate change in avian rhombomeres: intersegmental boundaries as barriers. Mech Dev. 51:1995;289-303.
36. Grapin-Botton A, Bonnin MA, Sieweke M, Le Douarin NM. Defined concentrations of a posteriorizing signal are critical for MafB/Kreisler segmental expression in the hindbrain. of special interest Development. 125:1998;1173-1181 Shows that rhombomeres and neural crest cells can be re-specified by a posteriorizing morphogen from the somitic mesoderm. This effect can be mimicked by RA, which represses MafB/Kr expression in r5/6 in a dose-dependent manner.
37. Ensini M, Tsuchida TN, Belting HG, Jessell TM. The control of rostrocaudal pattern in the developing spinal cord: specification of motor neuron subtype identity is initiated by signals from paraxial mesoderm. of outstanding interest Development. 125:1998;969-982 Indicates an important role for somitic mesoderm in specifying the columnar identity of motor neurons along the rostrocaudal axis.
38. LaBonne C, Bronner-Fraser M. Induction and patterning of the neural crest, a stem cell-like precursor population. J Neurobiol. 36:1998;175-189.
39. Couly G, Grapin-Botton A, Coltey P, Le Douarin NM. The regeneration of the cephalic neural crest, a problem revisited: the regenerating cells originate from the contralateral or from the anterior and posterior neural fold. Development. 122:1996;3393-3407.
40. Wassarman KM, Lewandoski M, Campbell K, Joyner AL, Rubenstein JL, Martinez S, Martin GR. Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. of special interest Development. 124:1997;2923-2934 Demonstrates the importance of the homeobox gene Gbx2 in midbrain-hindbrain development, and shows that neural crest structures can be generated independently of CNS patterning.
41. Baker CV, Bronner-Fraser M, Le Douarin NM, Teillet MA. Early- and late-migrating cranial neural crest cell populations have equivalent developmental potential in vivo. of special interest Development. 124:1997;3077-3087 Demonstrates that early and late migrating mesencephalic neural crest cells have the same intrinsic developmental potential, and that differences in progeny are attributed solely to changes in the target environment.
42. Vicario-Abejon C, Johe KK, Hazel TG, Collazo D, McKay RD. Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons. Neuron. 15:1995;105-114.
43. Brüstle O, Maskos U, McKay RDG. Host-guided migration allows targeted introduction of neurons into the embryonic brain. Neuron. 15:1995;1275-1285.
44. Ferri RT, Levitt P. Cerebral cortical progenitors are fated to produce region-specific neuronal populations. Cereb Cortex. 3:1993;187-198.
45. Dyson S, Gurdon JB. The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. of outstanding interest Cell. 93:1998;557-568 A quantitative study showing that the absolute numbers of activin receptors occupied directly relates to different patterns of gene expression. This paper provides a mechanism by which morphogen gradients produce differing cell fates.
46. Anderson SA, Eisenstat DD, Shi L, Rubenstein JL. Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes. of outstanding interest Science. 278:1997;474-476 A tour de force of mouse genetics reporting the phenotype of a double knock out of Dlx genes. The Dlx genes are only expressed in the ventral forebrain but the block to neuronal differentiation was also found in dorsal cortical structures.
47. Tamamaki N, Fujimori KE, Takauji R. Origin and route of tangentially migrating neurons in the developing neocortical intermediate zone. J Neurosci. 17:1997;8313-8323.
48. Luskin MB, Zigova T, Soteres BJ, Stewart RR. Neuronal progenitor cells derived from the anterior sub ventricular zone of the neonatal rat forebrain continue to proliferate in vitro and express a neuronal phenotype. Mol Cell Neurosci. 8:1997;351-366.
49. Wichterle H, Garci-Verdugo J, Alvarez-Buylla A. Direct evidence for homotypic, glia-independent neuronal migration. Neuron. 18:1997;779-791.
50. Morrison SJ, Shah NM, Anderson DJ. Regulatory mechanisms in stem cell biology. Cell. 88:1997;287-298.
51. McKay R. Stem cells in the central nervous system. Science. 276:1997;66-71.
52. Williams BP, Park JK, Alberta JA, Muhlebach SG, Hwang GY, Roberts TM, Stiles CD. A PDGF-regulated immediate early gene response initiates neuronal differentiation in ventricular zone progenitor cells. Neuron. 18:1997;553-562.
53. Lillien L. Changes in retinal cell fate induced by overexpression of EGF. Nature. 377:1995;158-162.
54. Rajan P, McKay RD. Multiple routes to astrocytic differentiation in the CNS. J Neurosci. 18:1998;3620-3629.
55. Bonni A, Sun Y, Nadal-Vicens M, Bhatt A, Frank DA, Rozovsky I, Stahl N, Yancopoulos GD, Greenberg ME. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway. Science. 278:1997;477-483.
56. Stemple DL, Anderson DJ. Isolation of a stem cell for neurons and glia from the mammalian. Cell. 71:1992;973-985.
57. Shah NM, Marchionni MA, Isaacs I, Stroobant P, Anderson DJ. Glial growth factor restricts mammalian neural crest stem cells to a glial fate. Cell. 77:1994;349-360.
58. Shah NM, Groves AK, Anderson DJ. Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members. Cell. 85:1996;331-343.
59. Reissmann E, Ernsberger U, Francis-West PH, Rueger D, Brickell PM, Rohrer H. Involvement of bone morphogenetic protein 4 and bone morphogenetic protein 7 in the differentiation of the adrenergic phenotype in developing sympathetic neurons. Development. 122:1996;2079-2088.
60. Gross RE, Mehler MF, Mabie PC, Zang Z, Santschi L, Kessler JA. Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells. Neuron. 17:1996;595-606.
61. Josephson R, Muller T, Pickel J, Okabe S, Reynolds K, Turner PA, Zimmer A, McKay RD. POU transcription factors control expression of CNS stem cell-specific genes. of outstanding interest Development. 125:1998;3087-3100 Provides evidence for the global control of CNS stem cell-specific transcription by showing that POU-domain proteins regulate the expression of both nestin and BFABP.
62. Glass CK, Rose DW, Rosenfeld MG. Nuclear receptor coactivators. Curr Opin Cell Biol. 9:1997;222-232.
63. Price ER, Ding HF, Badalian T, Bhattacharya S, Takemoto C, Yao TP, Hemesath TJ, Fisher DE. Lineage-specific signaling in melanocytes. C-kit stimulation recruits p300/CBP to microphthalmia. J Biol Chem. 273:1998;17983-17986.
64. Puri PL, Avantaggiati ML, Balsano C, Sang N, Graessmann A, Giordano A, Levrero M. p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription. EMBO J. 16:1997;369-383.
65. Yao TP, Oh SP, Fuchs M, Zhou ND, Ch'ng LE, Newsome D, Bronson RT, Li E, Livingston DM, Eckner R. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell. 93:1998;361-372.
66. Pouponnot C, Jayaraman L, Massagué J. Physical and functional interaction of SMADs and p300/CBP. J Biol Chem. 273:1998;22865-22868.
67. Enver T, Greaves M. Loops, lineage, and leukemia. Cell. 94:1998;9-12.
68. Parnavelas JG, Barfield JA, Franke E, Luskin MB. Separate progenitor cells give rise to pyramidal and nonpyramidal neurons in the rat telencephalon. Cereb Cortex. 1:1991;463-468.
69. Mione MC, Danevic C, Boardman P, Harris B, Parnavelas JG. Lineage analysis reveals neurotransmitter (GABA or glutamate) but not calcium-binding protein homogeneity in clonally related cortical neurons. J Neurosci. 14:1994;107-123.
70. Tan SS, Kalloniatis M, Sturm K, Tam PP, Reese BE, Faulkner-Jones B. Separate progenitors for radial and tangential cell dispersion during development of the cerebral neocortex. Neuron. 21:1998;295-304.
71. McConnell SK, Kaznowski CE. Cell cycle dependence of laminar determination in developing neocortex. Science. 254:1991;282-285.
72. Turner DL, Cepko CL. A common progenitor for neurons and glia persists in rat retina late in development. Nature. 328:1987;131-136.
73. Austin CP, Feldman DE, Ida JA Jr, Cepko CL. Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch. Development. 121:1995;3637-3650.
74. Studer L, Tabar V, McKay RD. Transplantation of expanded mesencephalic precursors leads to recovery in Parkinsonian rats. Nat Neuro. 1:1998;290-295.
75. Brustle O, Choudary K, Karam K, Huttner A, Murray K, Dubois-Dalcq M, McKay R. Chimeric brains generated by intraventricular transplantation of fetal human brain cells into embryonic rats. Nat Biotechnol. 1998;. in press.