The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation

Genes and Development

Volumn 19, Issue 22, 2005, Pages 2656-2667

  Uziel, Tamar ^a   Zindy, Frederique ^a   Xie, Suqing ^a   Lee, Youngsoo ^a   Forget, Antoine ^a   Magdaleno, Susan ^a   Rehg, Jerold E ^a   Calabrese, Christopher ^a   Solecki, David ^c   Eberhart, Charles G ^b   Sherr, Sarah E ^a   Plimmer, Sarah ^d   Clifford, Steven C ^d   Hatten, Mary E ^c   McKinnon, Peter J ^a   Gilbertson, Richard J ^a   Curran, Tom ^a   Sherr, Charles J ^a   Roussel, Martine F ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Cyclin dependent kinase inhibitors; Haploinsufficiency; Sonic hedgehog signaling

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 2C; PROTEIN P53; PROTEIN PATCHED; SONIC HEDGEHOG PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CELL DIFFERENTIATION; CELL DIVISION; CELL PROLIFERATION; CEREBELLUM; CONTROLLED STUDY; GENE INACTIVATION; GRANULE CELL; HAPLOTYPE; HETEROZYGOTE; IRRADIATION; MEDULLOBLASTOMA; METHYLATION; MOUSE; NERVE CELL CULTURE; NEURAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PENETRANCE; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TUMOR CELL; TUMOR SUPPRESSOR GENE; WILD TYPE;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CEREBELLUM; CYCLIN-DEPENDENT KINASE INHIBITOR P18; HEDGEHOG PROTEINS; HUMANS; MEDULLOBLASTOMA; MICE; MICE, KNOCKOUT; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; ERINACEIDAE;

EID: 27744450224     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1368605     Document Type: Article

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