Transient activaton of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours

Development

Volumn 131, Issue 8, 2004, Pages 1787-1799

  Celso, Cristina Lo ^a   Prowse, David M ^a,b   Watt, Fiona M ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

catenin; Differentiation; Stem cells; Trichofolliculoma

Indexed keywords

4 HYDROXYTAMOXIFEN; BETA CATENIN; ESTROGEN RECEPTOR; KERATIN; LIGAND; MUTANT PROTEIN; SONIC HEDGEHOG PROTEIN; CATNB PROTEIN, MOUSE; CYTOSKELETON PROTEIN; TRANSACTIVATOR PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BENIGN TUMOR; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EPIDERMIS; FEMALE; GENE FUSION; HAIR FOLLICLE; HAIR GROWTH; LIGAND BINDING; MALE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN STABILITY; SEBACEOUS GLAND; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TRICHILEMMOMA; TRICHOEPITHELIOMA; TUMOR REGRESSION; ANIMAL; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY; SKIN TUMOR; TIME;

ANIMALIA; ERINACEIDAE; MAMMALIA; MUS MUSCULUS;

ANIMALS; BETA CATENIN; CYTOSKELETAL PROTEINS; EPIDERMIS; HAIR FOLLICLE; MICE; MICE, TRANSGENIC; PROMOTER REGIONS (GENETICS); SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TIME FACTORS; TRANS-ACTIVATORS;

EID: 2342427631     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01052     Document Type: Article

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