Current concepts in the molecular genetics of pediatric brain tumors: Implications for emerging therapies

Child's Nervous System

Volumn 22, Issue 11, 2006, Pages 1379-1394

  Tamber, Mandeep S ^a   Bansal, Krishan ^a   Liang, Muh Lii ^a   Mainprize, Todd G ^a   Salhia, Bodour ^a   Northcott, Paul ^a   Taylor, Michael ^a   Rutka, James T ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Brain neoplasms; Molecular biology; Pediatrics; Review; Therapeutics

Indexed keywords

APC PROTEIN; BETA CATENIN; CALVASCULIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FIBROBLAST GROWTH FACTOR 1; GEFITINIB; GLYCOGEN SYNTHASE KINASE 3BETA; HOX PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P14ARF; PROTEIN P16INK4A; PROTEIN P53; PROTEIN P63; PROTEIN PATCHED; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; RETINOBLASTOMA PROTEIN; SONIC HEDGEHOG PROTEIN; STAT PROTEIN; TRANSCRIPTION FACTOR GLI1; UNINDEXED DRUG; WNT PROTEIN;

ACCURACY; ANTINEOPLASTIC ACTIVITY; ASTROCYTOMA; BRAIN TUMOR; CANCER GENETICS; CANCER GRADING; CARCINOGENESIS; CHILDHOOD CANCER; CHROMOSOME LOSS; COMPARATIVE GENOMIC HYBRIDIZATION; DIAGNOSTIC ACCURACY; DNA MICROARRAY; EPENDYMOMA; EWING SARCOMA; GENE DELETION; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; GERM CELL TUMOR; GLIOBLASTOMA; GLIOMA; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; INTERMETHOD COMPARISON; MEDULLOBLASTOMA; MOLECULAR MECHANICS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVIEW; RHABDOID TUMOR; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SPECTRAL KARYOTYPING;

ANIMALS; BRAIN NEOPLASMS; HUMANS; MOLECULAR BIOLOGY; PEDIATRICS;

EID: 33750441471     PISSN: 02567040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00381-006-0187-3     Document Type: Review

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