TrkC expression predicts good clinical outcome in primitive neuroectodermal brain tumors

Journal of Clinical Oncology

Volumn 18, Issue 5, 2000, Pages 1027-1035

  Grotzer, M A ^a   Janss, A J ^a   Fung, K M ^a   Biegel, J A ^a   Sutton, L N ^a   Rorke, L B ^a   Zhao, H ^a   Cnaan, A ^a   Phillips, P C ^a   Lee, V M Y ^a   Trojanowski, J Q ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NEUROTROPHIN RECEPTOR;

ADOLESCENT; ADULT; ARTICLE; BRAIN TUMOR; CANCER SURVIVAL; CHILD; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MICROSCOPY; NEUROECTODERM TUMOR; OUTCOMES RESEARCH; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGRESSION ANALYSIS; SCHOOL CHILD; TREATMENT PLANNING;

EID: 0033994659     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/jco.2000.18.5.1027     Document Type: Article

References (50)

1. Packer RJ, Siegel KR, Sutton LN, et al: Efficacy of adjuvant chemotherapy for patients with poor-risk medulloblastoma: A preliminary report. Ann Neurol 24:503-508, 1988
2. Olshan JS, Gubernick J, Packer R, et al: The effects of adjuvant chemotherapy on growth in children with medulloblastoma. Cancer 70:2013-2017, 1992
3. Radcliffe J, Packer RJ, Atkins TE, et al: Three- and four-year cognitive outcome in children with noncortical brain tumors treated with whole-brain radiotherapy. Ann Neurol 32:551-554, 1992
4. Silber JH, Radcliffe J, Peckham V, et al: Whole-brain irradiation and decline in intelligence: The influence of dose and age on IQ score. J Clin Oncol 10:1390-1396, 1992
5. Dennis M, Spiegler BJ, Hetherington CR, et al: Neuropsychological sequelae of the treatment of children with medulloblastoma. J Neurooncol 29:91-101, 1996
6. Chapman CA, Waber DP, Bernstein JH, et al: Neurobehavioral and neurologic outcome in long term survivors of posterior fossa brain tumors: Role of age and perioperative factors. J Child Neurol 10:209-212, 1996
7. Silverman CL, Palkes H, Talent B, et al: Late effects of radiotherapy of patients with cerebellar medulloblastoma. Cancer 54:825-829, 1984
8. Goldwein JW, Radcliffe J, Johnson J, et al: Updated results of a pilot study of low dose craniospinal irradiation plus chemotherapy for children under five with cerebellar primitive neuroectodermal tumors (medulloblastoma). Int J Radiat Oncol Biol Phys 34:899-904, 1996
9. Janss AJ, Yachnis AT, Silber JH, et al: Glial differentiation predicts poor clinical outcome in primitive neuroectodermal brain tumors. Ann Neurol 39:481-489, 1996
10. Evans AE, Jenkin DT, Sposto R, et al: The treatment of medulloblastoma. J Neurosurg 72:572-582, 1990
11. Garton GR, Schomberg PJ, Scheithauer BW, et al: Medulloblastoma: Prognostic factors and outcome of treatment - Review of the Mayo Clinic experience. Mayo Clin Proc 65:1077-1086, 1990
12. Packer RJ, Sutton LN, Elterman R, et al: Outcome for children with medulloblastoma treated with radiation and cisplatin, CCNU, and vincristine chemotherapy. J Neurosurg 81:690-698, 1994
13. Weil MD, Lamborn K, Edwards MS, et al: Influence of a child's sex on medulloblastoma outcome. JAMA 13:1474-1476, 1998
14. Albright AL, Wisoff JH, Zeltzer PM, et al: Effects of medulloblastoma resections on outcome in children: A report from the Children's Cancer Group. Neurosurgery 38:265-271, 1996
15. Cohen BH, Zeltzer PM, Boyett JM: Prognostic factors and treatment results for supratentorial primitive neuroectodermal tumors in children using radiation and chemotherapy: A Childrens Cancer Group randomized trial. J Clin Oncol 13:1687-1696, 1995
16. Berry MP, Jenkin RDT, Keen CW, et al: Radiation treatment for medulloblastoma. J Neurosurg 55:43-51, 1981
17. Merchant TE, Wang M-H, Haida T, et al: Medulloblastoma: Long-term results for patients treated with definitive radiation therapy during the computed tomography era. Int J Radiat Oncol Biol Phys 36:29-35, 1996
18. Pezzotta S, Cordero di Montezemolo L, Knerich R, et al: CNS-85 trial: A cooperative pediatric CNS tumor study - Results of treatment of medulloblastoma patients. Childs Nerv Syst 12:87-96, 1996
19. Sure U, Berghorn WJ, Bertalanffy H, et al: Staging, scoring and grading of medulloblastoma: A postoperative prognosis predicting system based on the cases of a single institute. Acta Neurochir (Wien) 132:59-65, 1995
20. Tait DM, Thornton-Jones H, Bloom HJG, et al: Adjuvant chemotherapy for medulloblastoma: The first multi-centre control trial of the International Society of Paediatric Oncology (SIOP I). Eur J Cancer 26:464-469, 1990
21. Caputy AJ, McCullough DC, Manz HJ, et al: A review of the factors influencing the prognosis of medulloblastoma. J Neurosurg 66:80-87, 1987
22. Tomita T, Yasue M, Engelhard HH, et al: Flow cytometric DNA analysis of medulloblastoma. Cancer 61:744-749, 1988
23. Czerwionka M, Korf H-W, Hoffmann O, et al: Differentiation in medulloblastomas: Correlation between the immunocytochemical demonstration of photoreceptor markers (S-antigen, rod-opsin) and the survival rate in 66 patients. Acta Neuropathol (Berl) 78:629-636, 1989
24. Goldberg-Stern H, Gadoth N, Stern S, et al: The prognostic significance of glial fibrillary acidic protein staining in medulloblastoma. Cancer 68:568-573, 1991
25. Schoneld DE, Yunis EJ, Geyer R, et al: DNA content and other prognostic features in childhood medulloblastoma: Proposal of a scoring system. Cancer 69:1307-1314, 1992
26. Maraziotis T, Perentes E, Karamitopoulou E, et al: Neuron-associated class III beta-tubulin isotype, retinal S-antigen, synaptophysin, and glial fibrillary acidic protein in human medulloblastomas: A clinicopathological analysis of 36 cases. Acta Neuropathol (Berl) 84:355-363, 1992
27. Zerbini C, Gelber RD, Weinberg D, et al: Prognostic factors in medulloblastoma, including DNA ploidy. J Clin Oncol 11:616-622, 1993
28. Segal RA, Goumnerova LC, Kwon YK, et al: Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proc Natl Acad Sci U S A 91:12867-12871, 1994
29. Cogen PH, McDonald JD: Tumor suppressor genes and medulloblastoma. J Neurooncol 29:103-112, 1996
30. Biegel JA, Janss AJ, Raffel C, et al: Prognostic significance of chromosome 17p deletions in childhood primitive neuroectodermal tumors (medulloblastomas) of the central nervous system. Clin Cancer Res 3:473-478, 1997
31. Gilbertson RJ, Perry RH, Kelly PJ, et al: Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma. Cancer Res 57:3272-3280, 1997
32. Scheurlen WG, Schwabe GC, Joos S, et al: Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome. J Clin Oncol 16:2478-2485, 1998
33. Brodeur GM, Seeger RC, Schwab M, et al: Amplification of N-myc in untreated human neuroblastoma correlates with advanced disease stage. Science 224:1121-1124, 1984
34. Nakagawara A, Arima-Nakagawara M, Scavarda NJ, et al: Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma. N Engl J Med 328:847-854, 1993
35. Maris JM, White PS, Beltinger CP, et al: Significance of chromosome 1p loss of heterozygosity in neuroblastoma. Cancer Res 55:4664-4669, 1995
36. Lindsay RM, Wiegand SJ, Altar CA, et al: Neurotrophic factors: From molecule to man. Trends Neurosci 17:182-190, 1994
37. Chao MV: Neurotrophin receptors: A window into neuronal differentiation. Neuron 9:583-593, 1992
38. Barbacid M: Nerve growth factor: A tale of two receptors. Oncogene 8:2033-2042, 1993
39. Korsching S: The neurotrophic factor concept: A reexamination. J Neurosci 13:2739-2748, 1993
40. Barbacid M: The Trk family of neurotrophin receptors. J Neurobiol 25:1386-1403, 1994
41. Kim JY, Sutton ME, Lu DJ, et al: Activation of neurotrophin-3 receptor TrkC induces apoptosis in medulloblastomas. Cancer Res 59:711-719, 1999
42. Chang CH, Housepian EM, Herbert C: An operative staging system and a megavoltage radiotherapeutic technique for cerebellar medulloblastomas. Radiology 93:1351-1359, 1969
43. Duffner PK, Horowitz ME, Krischer JP, et al: Postoperative chemotherapy and delayed radiation in children less than three years of age with malignant brain tumors. N Engl J Med 328:1725-1731, 1993
44. Shelton DL, Sutherland J, Gripp J, et al: Human trks: Molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins. J Neurosci 15:477-491, 1995 (1 pt 2)
45. Muragaki Y, Chou TT, Kaplan DR, et al: Nerve growth factor induces apoptosis in human medulloblastoma cell lines that express TrkA receptor. J Neurosci 17:530-542, 1997
46. Rorke LB: The cerebellar medulloblastoma and its relationship to primitive neuroectodermal tumors. J Neuropathol Exp Neurol 42:1-15, 1983
47. Rorke LB, Trojanowski JQ, Lee VM, et al: Primitive neuroectodermal tumors of the central nervous system. Brain Pathol 7:765-784, 1997
48. Tajima Y, Molina RP, Rorke LB, et al: Neurotrophins and neuronal versus glial differentiation in medulloblastomas and other pediatric brain tumors. Acta Neuropathol (Berl) 95:325-332, 1998
49. Washiyama K, Muragaki Y, Rorke LB, et al: Neurotrophin and neurotrophin receptor proteins in medulloblastomas and other primitive neuroectodermal tumors of the pediatric central nervous system. Am J Pathol 148:929-940, 1996
50. Brodeur GM, Nakagawara A, Yamashiro DJ, et al: Expression of TrkA, TrkB, and TrkC in human neuroblastomas. J Neurooncol 31:49-55, 1997