-
1
-
-
0025726660
-
Chromosome 9 deletion mapping reveals interferon α and interferon β-1 deletions in human glial tumors
-
James CD He J Carlbom E Chromosome 9 deletion mapping reveals interferon α and interferon β-1 deletions in human glial tumors Cancer Res 51 1991 1684 1688
-
(1991)
Cancer Res
, vol.51
, pp. 1684-1688
-
-
James, CD1
He, J2
Carlbom, E3
-
2
-
-
0026683968
-
Molecular analysis of deletions of the short arm of chromosome 9 in human gliomas
-
Olopade OI Jenkins RB Ransom DT Molecular analysis of deletions of the short arm of chromosome 9 in human gliomas Cancer Res 52 1992 2523 2529
-
(1992)
Cancer Res
, vol.52
, pp. 2523-2529
-
-
Olopade, OI1
Jenkins, RB2
Ransom, DT3
-
3
-
-
0027958498
-
Molecular and cytogenetic analysis of chromosome 9 deletions in 75 malignant gliomas
-
Bello MJ de Campos JM Vaquero J Molecular and cytogenetic analysis of chromosome 9 deletions in 75 malignant gliomas Genes Chromosomes Cancer 9 1994 33 41
-
(1994)
Genes Chromosomes Cancer
, vol.9
, pp. 33-41
-
-
Bello, MJ1
de Campos, JM2
Vaquero, J3
-
4
-
-
0028935143
-
Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in situ hybridization
-
Dreyling MH Bohlander SK Adeyanju MO Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in situ hybridization Cancer Res 55 1995 984 988
-
(1995)
Cancer Res
, vol.55
, pp. 984-988
-
-
Dreyling, MH1
Bohlander, SK2
Adeyanju, MO3
-
5
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
Kamb A Gruis NA Weaver-Feldhaus J A cell cycle regulator potentially involved in genesis of many tumor types Science 264 1994 436 440
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A1
Gruis, NA2
Weaver-Feldhaus, J3
-
6
-
-
0028033422
-
Rates of p16 (MTS1) mutations in primary tumors with 9p loss
-
Cairns P Mao L Merlo A Rates of p16 (MTS1) mutations in primary tumors with 9p loss Science 265 1994 415 416
-
(1994)
Science
, vol.265
, pp. 415-416
-
-
Cairns, P1
Mao, L2
Merlo, A3
-
7
-
-
0030909375
-
A correlative immunohistochemistry and molecular genetic study of the inactivation of the p16INK4A genes in astrocytomas
-
INK4A genes in astrocytomas Diagn Mol Pathol 6 1997 115 122
-
(1997)
Diagn Mol Pathol
, vol.6
, pp. 115-122
-
-
Rao, LS1
Miller, DC2
Newcomb, EW3
-
8
-
-
0031906358
-
Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas
-
Burns KL Ueki K Jhung SL Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas J Neuropathol Exp Neurol 57 1998 122 130
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 122-130
-
-
Burns, KL1
Ueki, K2
Jhung, SL3
-
9
-
-
0028986612
-
Loss of p16INK4 expression is frequent in high grade gliomas
-
INK4 expression is frequent in high grade gliomas Cancer Res 55 1995 1941 1945
-
(1995)
Cancer Res
, vol.55
, pp. 1941-1945
-
-
Nishikawa, R1
Furnari, FB2
Lin, H3
-
10
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo A Herman JG Mao L 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers Nature Med 1 1995 686 692
-
(1995)
Nature Med
, vol.1
, pp. 686-692
-
-
Merlo, A1
Herman, JG2
Mao, L3
-
11
-
-
0031012306
-
Infrequent methylation of CDKN2A (MTS1/p16) and rare mutation of both CDKN2A and CDKN2B (MTS2/p15) in primary astrocytic tumours
-
Schmidt EE Ichimura K Messerle KR Infrequent methylation of CDKN2A (MTS1/p16) and rare mutation of both CDKN2A and CDKN2B (MTS2/p15) in primary astrocytic tumours Br J Cancer 75 1997 2 8
-
(1997)
Br J Cancer
, vol.75
, pp. 2-8
-
-
Schmidt, EE1
Ichimura, K2
Messerle, KR3
-
12
-
-
0028018501
-
MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p
-
Ueki K Rubio M-P Ramesh V MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p Hum Mol Genet 3 1994 1841 1845
-
(1994)
Hum Mol Genet
, vol.3
, pp. 1841-1845
-
-
Ueki, K1
Rubio, M-P2
Ramesh, V3
-
13
-
-
0029156810
-
Frequent loss of heterozygosity on chromosome 9, and low incidence of mutations of cyclin-dependent kinase inhibitors p15 (MTS2) and p16 (MTS1) genes in gliomas
-
Li Y-J Hoang-Xuan K Delattre J-Y Frequent loss of heterozygosity on chromosome 9, and low incidence of mutations of cyclin-dependent kinase inhibitors p15 (MTS2) and p16 (MTS1) genes in gliomas Oncogene 11 1995 597 600
-
(1995)
Oncogene
, vol.11
, pp. 597-600
-
-
Li, Y-J1
Hoang-Xuan, K2
Delattre, J-Y3
-
14
-
-
0028930619
-
MTS1/p16/CDKN2 lesions in primary glioblastoma multiforme
-
Moulton T Samara G Chung W-Y MTS1/p16/CDKN2 lesions in primary glioblastoma multiforme Am J Pathol 146 1995 613 619
-
(1995)
Am J Pathol
, vol.146
, pp. 613-619
-
-
Moulton, T1
Samara, G2
Chung, W-Y3
-
15
-
-
0029060657
-
Complex structure and regulation of the p16 (MTS1) locus
-
Stone S Jiang P Dayananth P Complex structure and regulation of the p16 (MTS1) locus Cancer Res 55 1995 2988 2994
-
(1995)
Cancer Res
, vol.55
, pp. 2988-2994
-
-
Stone, S1
Jiang, P2
Dayananth, P3
-
16
-
-
0029587551
-
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
Quelle DE Zindy F Ashmun RA Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest Cell 83 1995 993 1000
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, DE1
Zindy, F2
Ashmun, RA3
-
17
-
-
0028929988
-
Replacement of the p16/CDK2 gene suppresses human glioma cell growth
-
Arap W Nishikawa R Furnari FB Replacement of the p16/CDK2 gene suppresses human glioma cell growth Cancer Res 55 1995 1351 1354
-
(1995)
Cancer Res
, vol.55
, pp. 1351-1354
-
-
Arap, W1
Nishikawa, R2
Furnari, FB3
-
18
-
-
0030613650
-
Functional analysis of wild-type and malignant glioma derived CDKN2Aβ alleles: Evidence for an RB-independent growth suppressive pathway
-
Arap W Knudsen E Sewell DA Functional analysis of wild-type and malignant glioma derived CDKN2Aβ alleles: Evidence for an RB-independent growth suppressive pathway Oncogene 15 1997 2013 2020
-
(1997)
Oncogene
, vol.15
, pp. 2013-2020
-
-
Arap, W1
Knudsen, E2
Sewell, DA3
-
19
-
-
0028061974
-
CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines
-
He J Allen JR Collins VP CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines Cancer Res 54 1994 5804 5807
-
(1994)
Cancer Res
, vol.54
, pp. 5804-5807
-
-
He, J1
Allen, JR2
Collins, VP3
-
20
-
-
0030070484
-
CDKN2/p16 or Rb alterations occur in the majority of glioblastomas and are inversely correlated
-
Ueki K Ono Y Henson JW CDKN2/p16 or Rb alterations occur in the majority of glioblastomas and are inversely correlated Cancer Res 56 1996 150 153
-
(1996)
Cancer Res
, vol.56
, pp. 150-153
-
-
Ueki, K1
Ono, Y2
Henson, JW3
-
21
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53 Cell 92 1998 713 723
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J1
Schreiber-Agus, N2
Liegeois, NJ3
-
22
-
-
0027244853
-
The p53-mdm-2 autoregulatory feedback loop
-
Wu X Bayle JH Olson D The p53-mdm-2 autoregulatory feedback loop Genes Dev 7 1993 1126 1132
-
(1993)
Genes Dev
, vol.7
, pp. 1126-1132
-
-
Wu, X1
Bayle, JH2
Olson, D3
-
23
-
-
0030797470
-
Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme
-
Hayashi Y Ueki K Waha A Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme Brain Pathol 7 1997 871 875
-
(1997)
Brain Pathol
, vol.7
, pp. 871-875
-
-
Hayashi, Y1
Ueki, K2
Waha, A3
-
24
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
ARF Cell 91 1997 649 659
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T1
Zindy, F2
Roussel, MF3
-
25
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and mortality
-
Serrano M Lee H-W Chin L Role of the INK4a locus in tumor suppression and mortality Cell 85 1996 27 37
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M1
Lee, H-W2
Chin, L3
-
26
-
-
0028618304
-
Deletion of p16 and p15 genes in brain tumors
-
Jen JJ Harper W Bigner SH Deletion of p16 and p15 genes in brain tumors Cancer Res 54 1994 6353 6358
-
(1994)
Cancer Res
, vol.54
, pp. 6353-6358
-
-
Jen, JJ1
Harper, W2
Bigner, SH3
-
27
-
-
0003692572
-
Histological Typing of Tumors of the Central Nervous System
-
Kleihues P Burger PC Scheithauer BW Histological Typing of Tumors of the Central Nervous System 1993 Springer-Verlag New York, NY
-
(1993)
-
-
Kleihues, P1
Burger, PC2
Scheithauer, BW3
-
28
-
-
0031679407
-
Survival of patients with glioblastoma multiforme is not influenced by altered expression of p16, p53, EGFR, MDM2 or Bcl-2 genes
-
Newcomb EW Cohen H Lee SR Survival of patients with glioblastoma multiforme is not influenced by altered expression of p16, p53, EGFR, MDM2 or Bcl-2 genes Brain Pathol 8 1998 655 667
-
(1998)
Brain Pathol
, vol.8
, pp. 655-667
-
-
Newcomb, EW1
Cohen, H2
Lee, SR3
-
29
-
-
0028087884
-
Pathways leading to glioblastoma multiforme: A molecular analysis of genetic alterations in 65 astrocytic tumors
-
Lang FF Miller DC Koslow M Pathways leading to glioblastoma multiforme: A molecular analysis of genetic alterations in 65 astrocytic tumors J Neurosurg 81 1994 427 436
-
(1994)
J Neurosurg
, vol.81
, pp. 427-436
-
-
Lang, FF1
Miller, DC2
Koslow, M3
-
30
-
-
0030890851
-
A rapid and nonisotopic method for screening and sequencing of p53 gene mutations in formalin-fixed, paraffin-embedded tumors
-
Soong R Iacopetta BJ A rapid and nonisotopic method for screening and sequencing of p53 gene mutations in formalin-fixed, paraffin-embedded tumors Mod Pathol 10 1997 252 258
-
(1997)
Mod Pathol
, vol.10
, pp. 252-258
-
-
Soong, R1
Iacopetta, BJ2
-
31
-
-
0029823960
-
Malignant astrocytomas with homozygous CDKN2/p16 gene deletions have higher Ki-67 proliferation indices
-
Ono Y Tamiya T Ichikawa T Malignant astrocytomas with homozygous CDKN2/p16 gene deletions have higher Ki-67 proliferation indices J Neuropathol Exp Neurol 55 1996 1026 1031
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 1026-1031
-
-
Ono, Y1
Tamiya, T2
Ichikawa, T3
-
32
-
-
0028832159
-
Reliability of differential P{CR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue
-
Hunter SB Abbott K Varma VA Reliability of differential P{CR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue J Neuropathol Exp Neurol 54 1995 57 64
-
(1995)
J Neuropathol Exp Neurol
, vol.54
, pp. 57-64
-
-
Hunter, SB1
Abbott, K2
Varma, VA3
-
33
-
-
0032480260
-
Bax cleavage is mediated by calpain during drug-induced apoptosis
-
Wood DE Thomas A Devi LA Bax cleavage is mediated by calpain during drug-induced apoptosis Oncogene 17 1998 1069 1078
-
(1998)
Oncogene
, vol.17
, pp. 1069-1078
-
-
Wood, DE1
Thomas, A2
Devi, LA3
-
34
-
-
0028652269
-
CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas
-
Schmidt EE Ichimura K Reifenberger G CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas Cancer Res 54 1994 6321 6324
-
(1994)
Cancer Res
, vol.54
, pp. 6321-6324
-
-
Schmidt, EE1
Ichimura, K2
Reifenberger, G3
-
35
-
-
0031030325
-
Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF
-
ARF Proc Natl Acad Sci 94 1997 669 673
-
(1997)
, pp. 669-673
-
-
Quelle, DE1
Cheng, M2
Ashmun, RA3
-
37
-
-
0031987331
-
Genomic alterations of the p19ARF encoding exons in T-cell acute lymphoblastic leukemia
-
ARF encoding exons in T-cell acute lymphoblastic leukemia Blood 91 1998 1016 1020
-
(1998)
Blood
, vol.91
, pp. 1016-1020
-
-
Gardie, B1
Cayuela, J-M2
Martini, S3
-
38
-
-
0032148385
-
The human p19ARF protein encoded by the β transcript of the p16INK4a gene is frequently lost in small cell lung cancer
-
INK4a gene is frequently lost in small cell lung cancer Cancer Res 58 1998 3926 3931
-
(1998)
Cancer Res
, vol.58
, pp. 3926-3931
-
-
Gazzeri, S1
Della Valle, V2
Chaussade, L3
-
39
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppressor pathways
-
Zhang Y Xiong Y Yarbrough WG ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppressor pathways Cell 92 1998 725 734
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y1
Xiong, Y2
Yarbrough, WG3
-
40
-
-
0033130010
-
Nucleolar Arf sequesters Mdm2 and activates p53
-
Weber JD Taylor LJ Roussel MF Nucleolar Arf sequesters Mdm2 and activates p53 Nature Cell Biol 1 1999 20 26
-
(1999)
Nature Cell Biol
, vol.1
, pp. 20-26
-
-
Weber, JD1
Taylor, LJ2
Roussel, MF3
-
41
-
-
0031670668
-
Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms
-
Senderowicz AM Headlee D Stinson SF Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms J Clin Oncol 16 1998 2986 2999
-
(1998)
J Clin Oncol
, vol.16
, pp. 2986-2999
-
-
Senderowicz, AM1
Headlee, D2
Stinson, SF3
|