-
3
-
-
0024566034
-
Simultanenous presentation of glioblastoma multiforme in siblings two and five years old: Case report
-
Duhaime AC, Bunin G, Sutton L, Rorke LB, Packer RJ. Simultanenous presentation of glioblastoma multiforme in siblings two and five years old: Case report. Neurosurgery 1989;24:434-39
-
(1989)
Neurosurgery
, vol.24
, pp. 434-439
-
-
Duhaime, A.C.1
Bunin, G.2
Sutton, L.3
Rorke, L.B.4
Packer, R.J.5
-
4
-
-
0028872525
-
Familial brain tumor syndrome associated with a p53 germline deletion of codon 236
-
Lübbe J, von Ammon K, Watanabe K, Hegi ME, Kleihues P. Familial brain tumor syndrome associated with a p53 germline deletion of codon 236. Brain Pathol 1995;5:15-23
-
(1995)
Brain Pathol
, vol.5
, pp. 15-23
-
-
Lübbe, J.1
Von Ammon, K.2
Watanabe, K.3
Hegi, M.E.4
Kleihues, P.5
-
5
-
-
0027739843
-
Cytogenetic analysis of 109 pediatric central nervous system tumors
-
Neumann E, Kalousek DK, Norman MG, Steinbok P, Chochrane DD, Goddard K. Cytogenetic analysis of 109 pediatric central nervous system tumors. Cancer Genet Cytogenet 1993;71:40-49
-
(1993)
Cancer Genet Cytogenet
, vol.71
, pp. 40-49
-
-
Neumann, E.1
Kalousek, D.K.2
Norman, M.G.3
Steinbok, P.4
Chochrane, D.D.5
Goddard, K.6
-
6
-
-
0027407245
-
Subsets of glioblastoma multiforme defined by molecular genetic analysis
-
von Deimling A, von Ammon K, Schoenfeld D, Wiestler OD, Seizinger BR, Louis DN. Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Pathol 1993;3:19-26
-
(1993)
Brain Pathol
, vol.3
, pp. 19-26
-
-
Von Deimling, A.1
Von Ammon, K.2
Schoenfeld, D.3
Wiestler, O.D.4
Seizinger, B.R.5
Louis, D.N.6
-
7
-
-
0027261003
-
Molecular genetics of pediatric brain stem gliomas. Application of PCR techniques to small and archival brain tumor specimens
-
Louis DN, Rubio M-P, Correa KM, Gusella JF, von Deimling A. Molecular genetics of pediatric brain stem gliomas. Application of PCR techniques to small and archival brain tumor specimens. J Neuropathol Exp Neurol 1993;52:507-15
-
(1993)
J Neuropathol Exp Neurol
, vol.52
, pp. 507-515
-
-
Louis, D.N.1
Rubio, M.-P.2
Correa, K.M.3
Gusella, J.F.4
Von Deimling, A.5
-
8
-
-
0028087884
-
Pathways leading to glioblastoma multiforme: A molecular analysis of genetic alterations in 65 astrocytic tumors
-
Lang FF, Miller DC, Koslow M, Newcomb EW. Pathways leading to glioblastoma multiforme: A molecular analysis of genetic alterations in 65 astrocytic tumors. J Neurosurg 1994;81:427-36
-
(1994)
J Neurosurg
, vol.81
, pp. 427-436
-
-
Lang, F.F.1
Miller, D.C.2
Koslow, M.3
Newcomb, E.W.4
-
9
-
-
0021932240
-
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
-
Libermann TA, Nusbaum HR, Razon N, Kris R, Lax I, Soreq H, et al. Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature 1985;313:144-47
-
(1985)
Nature
, vol.313
, pp. 144-147
-
-
Libermann, T.A.1
Nusbaum, H.R.2
Razon, N.3
Kris, R.4
Lax, I.5
Soreq, H.6
-
10
-
-
0025790916
-
Genes for epidermal growth factor receptor, transforming growth factor α, and epidermal growth factor and their expression in human gliomas in vivo
-
Ekstrand AJ, James CD, Cavenee WK, Seliger B, Petterson RF, Collins VP. Genes for epidermal growth factor receptor, transforming growth factor α, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res 1991;51:2164-72
-
(1991)
Cancer Res
, vol.51
, pp. 2164-2172
-
-
Ekstrand, A.J.1
James, C.D.2
Cavenee, W.K.3
Seliger, B.4
Petterson, R.F.5
Collins, V.P.6
-
11
-
-
0023429079
-
Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
-
Wong AJ, Bigner SH, Bigner DD, Kinzler KW, Hamilton SR, Vogelstein B. Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proc Natl Acad Sci USA 1987;84:6899-6903
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 6899-6903
-
-
Wong, A.J.1
Bigner, S.H.2
Bigner, D.D.3
Kinzler, K.W.4
Hamilton, S.R.5
Vogelstein, B.6
-
12
-
-
0028832159
-
Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE Glioma tissue
-
Hunter SB, Abbott K, Varma VA, Olson JJ, Barnett DW, James CD. Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE Glioma tissue. J Neuropathol Exp Neurol 1995;54:57-64
-
(1995)
J Neuropathol Exp Neurol
, vol.54
, pp. 57-64
-
-
Hunter, S.B.1
Abbott, K.2
Varma, V.A.3
Olson, J.J.4
Barnett, D.W.5
James, C.D.6
-
13
-
-
0028882666
-
Genetic alterations associated with the evolution and progression of astrocytic brain tumours
-
Ohgaki H, Schäuble B, zur Hausen A, von Ammon K, Kleihues P. Genetic alterations associated with the evolution and progression of astrocytic brain tumours. Virchows Arch 1995;427:113-18
-
(1995)
Virchows Arch
, vol.427
, pp. 113-118
-
-
Ohgaki, H.1
Schäuble, B.2
Zur Hausen, A.3
Von Ammon, K.4
Kleihues, P.5
-
14
-
-
0030017885
-
Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas
-
Watanabe K, Tachibana O, Sato K, Yonekawa Y, Kleihues P, Ohgaki H. Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol 1996;6:217-24
-
(1996)
Brain Pathol
, vol.6
, pp. 217-224
-
-
Watanabe, K.1
Tachibana, O.2
Sato, K.3
Yonekawa, Y.4
Kleihues, P.5
Ohgaki, H.6
-
15
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
Kamb A, Gruis NA, Liu Q, Harshman K, Tavtigian SV, et al. A cell cycle regulator potentially involved in genesis of many tumor types. Science 1994;264:436-40
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Liu, Q.3
Harshman, K.4
Tavtigian, S.V.5
-
16
-
-
0028275733
-
Deletions of the cyclin-dependent kinase-4 inhibitor gene in mutliple human cancers
-
Nobori T, Miural K, Wu DJ, Takabayashi K, Carson DA. Deletions of the cyclin-dependent kinase-4 inhibitor gene in mutliple human cancers. Nature 1994;368:753-56
-
(1994)
Nature
, vol.368
, pp. 753-756
-
-
Nobori, T.1
Miural, K.2
Wu, D.J.3
Takabayashi, K.4
Carson, D.A.5
-
18
-
-
0028618304
-
Deletion of p16 and p15 genes in brain tumors
-
Jen J, Harper JW, Bigner SH, Bigner DD, Papadopoulos N, Markowitz S, et al. Deletion of p16 and p15 genes in brain tumors. Cancer Res 1994;54:6353-58
-
(1994)
Cancer Res
, vol.54
, pp. 6353-6358
-
-
Jen, J.1
Harper, J.W.2
Bigner, S.H.3
Bigner, D.D.4
Papadopoulos, N.5
Markowitz, S.6
-
20
-
-
0029916697
-
Immunohistochemical detection of CDKN2, retinoblastoma and p53 gene products in primary astrocytic tumors
-
Nakamura M, Konioshi N, Hiasa Y, Tsunoda S, Fukushima Y, Tsuzuki T, et al. Immunohistochemical detection of CDKN2, retinoblastoma and p53 gene products in primary astrocytic tumors. Int J Oncol 1996;8:889-93
-
(1996)
Int J Oncol
, vol.8
, pp. 889-893
-
-
Nakamura, M.1
Konioshi, N.2
Hiasa, Y.3
Tsunoda, S.4
Fukushima, Y.5
Tsuzuki, T.6
-
21
-
-
0029026094
-
Identical mutations in the p53 tumor suppressor gene in the glial and the sarcomatous components of gliosarcomas suggest a common origin from glial cells
-
Biernat W, Aguzzi A, Sure U, Grant JW, Kleihues P, Hegi ME. Identical mutations in the p53 tumor suppressor gene in the glial and the sarcomatous components of gliosarcomas suggest a common origin from glial cells. J Neuropathol Exp Neurol 1995;54:651-56
-
(1995)
J Neuropathol Exp Neurol
, vol.54
, pp. 651-656
-
-
Biernat, W.1
Aguzzi, A.2
Sure, U.3
Grant, J.W.4
Kleihues, P.5
Hegi, M.E.6
-
22
-
-
0027430022
-
Mutations of the p53 tumour suppressor gene in neoplasms of the human nervous system
-
Ohgaki H, Eibl RH, Schwab M, Reichel MB, Mariani L, Gehring M, et al. Mutations of the p53 tumour suppressor gene in neoplasms of the human nervous system. Molec Carcinog 1993;8:74-80
-
(1993)
Molec Carcinog
, vol.8
, pp. 74-80
-
-
Ohgaki, H.1
Eibl, R.H.2
Schwab, M.3
Reichel, M.B.4
Mariani, L.5
Gehring, M.6
-
23
-
-
0024756969
-
Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
-
Orita M, Suzuki Y, Sekiya T, Hayashi K. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 1989;5:874-79
-
(1989)
Genomics
, vol.5
, pp. 874-879
-
-
Orita, M.1
Suzuki, Y.2
Sekiya, T.3
Hayashi, K.4
-
24
-
-
0029890378
-
Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression
-
Reifenberger J, Ring GU, Gies U, Cobbers JMJL, Oberstrass J, An H-X, et al. Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression. J Neuropath Exp Neurol 1996;55:822-31
-
(1996)
J Neuropath Exp Neurol
, vol.55
, pp. 822-831
-
-
Reifenberger, J.1
Ring, G.U.2
Gies, U.3
Cobbers, J.M.J.L.4
Oberstrass, J.5
An, H.-X.6
-
25
-
-
0028800035
-
Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors
-
Moscatello DK, Hogado-Maruga M, Godwin AK, Ramirez G, Gunn G, Zoltick PW, et al. Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors. Cancer Res 1995;55:5536-39
-
(1995)
Cancer Res
, vol.55
, pp. 5536-5539
-
-
Moscatello, D.K.1
Hogado-Maruga, M.2
Godwin, A.K.3
Ramirez, G.4
Gunn, G.5
Zoltick, P.W.6
-
27
-
-
0028123442
-
The p53 gene and protein in human brain tumors
-
Louis DN. The p53 gene and protein in human brain tumors. J Neuropathol Exp Neurol 1994;53:11-21
-
(1994)
J Neuropathol Exp Neurol
, vol.53
, pp. 11-21
-
-
Louis, D.N.1
-
28
-
-
0028107586
-
High frequency of p53 protein accumulation without p53 gene mutation in human juvenile pilocytic, low grade and anaplastic astrocytomas
-
Lang FF, Miller DC, Pisharody S, Koslow M, Newcomb EW. High frequency of p53 protein accumulation without p53 gene mutation in human juvenile pilocytic, low grade and anaplastic astrocytomas. Oncogene 1994;9:949-54
-
(1994)
Oncogene
, vol.9
, pp. 949-954
-
-
Lang, F.F.1
Miller, D.C.2
Pisharody, S.3
Koslow, M.4
Newcomb, E.W.5
-
29
-
-
0028240974
-
The lack of a role for p53 in astrocytomas in pediatric patients
-
Litofsky NS, Hinton D, Raffel C. The lack of a role for p53 in astrocytomas in pediatric patients. Neurosurgery 1994;34:967-73
-
(1994)
Neurosurgery
, vol.34
, pp. 967-973
-
-
Litofsky, N.S.1
Hinton, D.2
Raffel, C.3
-
30
-
-
0026347639
-
p53 mutations in nonastrocytic human brain tumors
-
Ohgaki H, Eibl RH, Wiestler OD, Yasargil MG, Newcomb EW, Kleihues P. p53 mutations in nonastrocytic human brain tumors. Cancer Res 1991;51:6202-5
-
(1991)
Cancer Res
, vol.51
, pp. 6202-6205
-
-
Ohgaki, H.1
Eibl, R.H.2
Wiestler, O.D.3
Yasargil, M.G.4
Newcomb, E.W.5
Kleihues, P.6
-
31
-
-
0028006633
-
Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p
-
Reifenberger J, Reifenberger G, Liu L, James CD, Wechsler W, Collins VP. Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p. Am J Pathol 1994;145:1175-90
-
(1994)
Am J Pathol
, vol.145
, pp. 1175-1190
-
-
Reifenberger, J.1
Reifenberger, G.2
Liu, L.3
James, C.D.4
Wechsler, W.5
Collins, V.P.6
-
32
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res 1994;54:4855-78
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
33
-
-
0028221553
-
Germline p53 gene mutations in subsets of glioma patients
-
Kyritsis AP, Bondy ML, Xiao M, Berman EL, Cunningham JE, Lee PS, et al. Germline p53 gene mutations in subsets of glioma patients. JNCI 1994;86:344-48
-
(1994)
JNCI
, vol.86
, pp. 344-348
-
-
Kyritsis, A.P.1
Bondy, M.L.2
Xiao, M.3
Berman, E.L.4
Cunningham, J.E.5
Lee, P.S.6
-
34
-
-
0027370019
-
p53 gene mutations in pontine gliomas of juvenile onset
-
Zhang S, Feng X, Koga H, Ichikawa T, Abe S, Kumanishi T. p53 gene mutations in pontine gliomas of juvenile onset. Biochem Biophys Res Comm 1993;196:851-57
-
(1993)
Biochem Biophys Res Comm
, vol.196
, pp. 851-857
-
-
Zhang, S.1
Feng, X.2
Koga, H.3
Ichikawa, T.4
Abe, S.5
Kumanishi, T.6
-
35
-
-
0027166864
-
Mutation hotspots due to sunlight in the p53 gene of non-melanoma skin cancer
-
Ziegler A, Leffell DJ, Kunala S, Sharma HW, Gailani M, Simon JA, et al. Mutation hotspots due to sunlight in the p53 gene of non-melanoma skin cancer. Proc Natl Acad Sci USA 1993;90:4216-20
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4216-4220
-
-
Ziegler, A.1
Leffell, D.J.2
Kunala, S.3
Sharma, H.W.4
Gailani, M.5
Simon, J.A.6
-
36
-
-
0027386959
-
Comparative study of p53 gene alterations in human astrocytic tumors
-
Louis DN, von Deimling A, Chung RY, Rubio M-P, Whaley JM, Eibl RH, et al. Comparative study of p53 gene alterations in human astrocytic tumors. J Neuropathol Exp Neurol 1993;52:31-38
-
(1993)
J Neuropathol Exp Neurol
, vol.52
, pp. 31-38
-
-
Louis, D.N.1
Von Deimling, A.2
Chung, R.Y.3
Rubio, M.-P.4
Whaley, J.M.5
Eibl, R.H.6
-
37
-
-
0028299342
-
p53 in tumor pathology: Can we trust immunohistochemistry? - Revisited!
-
Hall PA, Lane DP. p53 in tumor pathology: Can we trust immunohistochemistry? - Revisited! J Pathol 1994;172:1-4
-
(1994)
J Pathol
, vol.172
, pp. 1-4
-
-
Hall, P.A.1
Lane, D.P.2
-
38
-
-
0027769876
-
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
-
Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Science 1993;366:704-7
-
(1993)
Science
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
39
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo A, Herman JG, Mao L, Lee MJ, Gabrielson E, Burger PC, et al. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995;1:686-92
-
(1995)
Nat Med
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, M.J.4
Gabrielson, E.5
Burger, P.C.6
-
40
-
-
0029967152
-
Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation
-
Costello JF, Berger MS, Huang H-JS, Cavenee WK. Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation. Cancer Res 1996;56:2405-10
-
(1996)
Cancer Res
, vol.56
, pp. 2405-2410
-
-
Costello, J.F.1
Berger, M.S.2
Huang, H.-J.S.3
Cavenee, W.K.4
-
41
-
-
0028970955
-
Lack of p16INK4 or retinoblastoma protein (pRb), or amplification-associated overexpression of cdk4 is observed in distinct subsets of malignant glial tumors and cell lines
-
He J, Olson JJ, James CD. Lack of p16INK4 or retinoblastoma protein (pRb), or amplification-associated overexpression of cdk4 is observed in distinct subsets of malignant glial tumors and cell lines. Cancer Res 1995;55:4833-36
-
(1995)
Cancer Res
, vol.55
, pp. 4833-4836
-
-
He, J.1
Olson, J.J.2
James, C.D.3
|