-
2
-
-
0035912144
-
Molecular predictors of survival after adjuvant chemotherapy for colon cancer
-
T. Watanabe, T.T. Wu, P.J. Catalano Molecular predictors of survival after adjuvant chemotherapy for colon cancer N Engl J Med 344 2001 1196 1206
-
(2001)
N Engl J Med
, vol.344
, pp. 1196-1206
-
-
Watanabe, T.1
Wu, T.T.2
Catalano, P.J.3
-
3
-
-
0027461840
-
Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer
-
W. Scheithauer, H. Rosen, G.V. Kornek Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer Br Med J 306 1993 752 755
-
(1993)
Br Med J
, vol.306
, pp. 752-755
-
-
Scheithauer, W.1
Rosen, H.2
Kornek, G.V.3
-
4
-
-
13744251436
-
Systemic therapy for colorectal cancer
-
J.A. Meyerhardt, R.J. Mayer Systemic therapy for colorectal cancer N Engl J Med 352 2005 476 487
-
(2005)
N Engl J Med
, vol.352
, pp. 476-487
-
-
Meyerhardt, J.A.1
Mayer, R.J.2
-
5
-
-
0026540496
-
Modulation of fluoropyrimidines: Role of dose and schedule of leucovorin administration
-
Z.G. Zhang, A. Harstrick, Y.M. Rustum Modulation of fluoropyrimidines role of dose and schedule of leucovorin administration Semin Oncol 19 1992 10 15
-
(1992)
Semin Oncol
, vol.19
, pp. 10-15
-
-
Zhang, Z.G.1
Harstrick, A.2
Rustum, Y.M.3
-
6
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
A. de Gramont, A. Figer, M. Seymour Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer J Clin Oncol 18 2000 2938 2947
-
(2000)
J Clin Oncol
, vol.18
, pp. 2938-2947
-
-
De Gramont, A.1
Figer, A.2
Seymour, M.3
-
7
-
-
0141789596
-
Current and ongoing trials with irinotecan in the United States
-
C.S. Fuchs Current and ongoing trials with irinotecan in the United States Semin Oncol 30 2003 9 17
-
(2003)
Semin Oncol
, vol.30
, pp. 9-17
-
-
Fuchs, C.S.1
-
8
-
-
0031714683
-
Clinical pharmacology of camptothecins
-
L. Iyer, M.J. Ratain Clinical pharmacology of camptothecins Cancer Chemother Pharmacol 42 suppl 1998 S31 S43
-
(1998)
Cancer Chemother Pharmacol
, vol.42
, Issue.SUPPL.
-
-
Iyer, L.1
Ratain, M.J.2
-
9
-
-
1842569206
-
A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
-
R.M. Goldberg, D.J. Sargent, R.F. Morton A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer J Clin Oncol 22 2004 23 30
-
(2004)
J Clin Oncol
, vol.22
, pp. 23-30
-
-
Goldberg, R.M.1
Sargent, D.J.2
Morton, R.F.3
-
10
-
-
0031864830
-
Oxaliplatin: Mechanism of action and antineoplastic activity
-
E. Raymond, S. Faivre, J.M. Woynarowski Oxaliplatin mechanism of action and antineoplastic activity Semin Oncol 25 1998 4 12
-
(1998)
Semin Oncol
, vol.25
, pp. 4-12
-
-
Raymond, E.1
Faivre, S.2
Woynarowski, J.M.3
-
11
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
H. Hurwitz, L. Fehrenbacher, W. Novotny Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer N Engl J Med 350 2004 2335 2342
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
13
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
J.F. Kerr, A.H. Wyllie, A.R. Currie Apoptosis a basic biological phenomenon with wide-ranging implications in tissue kinetics Br J Cancer 26 1972 239 257
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
14
-
-
0041568662
-
Pro-apoptotic activity of transiently expressed BCL-2 occurs independent of BAX and BAK
-
T. Subramanian, G. Chinnadurai Pro-apoptotic activity of transiently expressed BCL-2 occurs independent of BAX and BAK J Cell Biochem 89 2003 1102 1114
-
(2003)
J Cell Biochem
, vol.89
, pp. 1102-1114
-
-
Subramanian, T.1
Chinnadurai, G.2
-
15
-
-
0033047235
-
Apoptosis without caspases: An inefficient molecular guillotine?
-
C. Borner, L. Monney Apoptosis without caspases an inefficient molecular guillotine? Cell Death Diff 6 1999 497 507
-
(1999)
Cell Death Diff
, vol.6
, pp. 497-507
-
-
Borner, C.1
Monney, L.2
-
16
-
-
0035433420
-
Four deaths and a funeral: From caspases to alternative mechanisms
-
M. Leist, M. Jaattela Four deaths and a funeral from caspases to alternative mechanisms Nat Rev Mol Cell Biol 2 2001 589 598
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jaattela, M.2
-
17
-
-
0034641898
-
CD95's deadly mission in the immune system
-
P.H. Krammer CD95's deadly mission in the immune system Nature 407 2000 789 795
-
(2000)
Nature
, vol.407
, pp. 789-795
-
-
Krammer, P.H.1
-
18
-
-
0034630161
-
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
-
H. Walczak, P.H. Krammer The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems Exp Cell Res 256 2000 58 66
-
(2000)
Exp Cell Res
, vol.256
, pp. 58-66
-
-
Walczak, H.1
Krammer, P.H.2
-
19
-
-
0035369143
-
The mitochondrial apoptosome: A killer unleashed by the cytochrome seas
-
C. Adrain, S.J. Martin The mitochondrial apoptosome a killer unleashed by the cytochrome seas Trends Biochem Sci 26 2001 390 397
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 390-397
-
-
Adrain, C.1
Martin, S.J.2
-
20
-
-
0035816553
-
Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells
-
D. Chauhan, T. Hideshima, S. Rosen Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells J Biol Chem 276 2001 24453 24456
-
(2001)
J Biol Chem
, vol.276
, pp. 24453-24456
-
-
Chauhan, D.1
Hideshima, T.2
Rosen, S.3
-
22
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
C. Du, M. Fang, Y. Li Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition Cell 102 2000 33 42
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
-
23
-
-
0034719680
-
The transcription factor NF-kappaB: Control of oncogenesis and cancer therapy resistance
-
M.W. Mayo, A.S. Baldwin The transcription factor NF-kappaB control of oncogenesis and cancer therapy resistance Biochim Biophys Acta 1470 2000 M55 M62
-
(2000)
Biochim Biophys Acta
, vol.1470
-
-
Mayo, M.W.1
Baldwin, A.S.2
-
24
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
R. Hakem, A. Hakem, G.S. Duncan Differential requirement for caspase 9 in apoptotic pathways in vivo Cell 94 1998 339 352
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
-
25
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
H. Yoshida, Y.Y. Kong, R. Yoshida Apaf1 is required for mitochondrial pathways of apoptosis and brain development Cell 94 1998 739 750
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
-
26
-
-
0032143986
-
Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors Fas/Apo1 and DR3 and is lethal prenatally
-
E.E. Varfolomeev, M. Schuchmann, V. Luria Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors Fas/Apo1 and DR3 and is lethal prenatally Immunity 9 1998 267 276
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
-
27
-
-
7144263731
-
FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
-
W.C. Yeh, J.L. Pompa, M.E. McCurrach FADD essential for embryo development and signaling from some, but not all, inducers of apoptosis Science 279 1998 1954 1958
-
(1998)
Science
, vol.279
, pp. 1954-1958
-
-
Yeh, W.C.1
Pompa, J.L.2
McCurrach, M.E.3
-
28
-
-
0034676089
-
Cross-talk in cell death signaling
-
S. Roy, D.W. Nicholson Cross-talk in cell death signaling J Exp Med 192 2000 21 26
-
(2000)
J Exp Med
, vol.192
, pp. 21-26
-
-
Roy, S.1
Nicholson, D.W.2
-
29
-
-
0032785181
-
Serial killers: Ordering caspase activation events in apoptosis
-
E.A. Slee, C. Adrain, S.J. Martin Serial killers ordering caspase activation events in apoptosis Cell Death Differ 6 1999 1067 1074
-
(1999)
Cell Death Differ
, vol.6
, pp. 1067-1074
-
-
Slee, E.A.1
Adrain, C.2
Martin, S.J.3
-
30
-
-
0038668000
-
Escaping cell death: Survival proteins in cancer
-
M. Jaattela Escaping cell death survival proteins in cancer Exp Cell Res 248 1999 30 43
-
(1999)
Exp Cell Res
, vol.248
, pp. 30-43
-
-
Jaattela, M.1
-
31
-
-
0037377102
-
Defects in the apoptotic machinery of cancer cells: Role in drug resistance
-
B. Zhivotovsky, S. Orrenius Defects in the apoptotic machinery of cancer cells role in drug resistance Semin Cancer Biol 13 2003 125 134
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 125-134
-
-
Zhivotovsky, B.1
Orrenius, S.2
-
33
-
-
0027763413
-
Cell division versus cell death: A functional model of multistep neoplasia
-
T.J. McDonnell Cell division versus cell death a functional model of multistep neoplasia Mol Carcinog 8 1993 209 213
-
(1993)
Mol Carcinog
, vol.8
, pp. 209-213
-
-
McDonnell, T.J.1
-
34
-
-
0025835716
-
BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death
-
D.M. Hockenbery, M. Zutter, W. Hickey BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death Proc Natl Acad Sci U S A 88 1991 6961 6965
-
(1991)
Proc Natl Acad Sci U S a
, vol.88
, pp. 6961-6965
-
-
Hockenbery, D.M.1
Zutter, M.2
Hickey, W.3
-
35
-
-
0032910650
-
Deregulation of apoptosis in colorectal carcinoma: Theoretical and therapeutic implications
-
L.M. Butler, P.J. Hewett, R.A. Fitridge Deregulation of apoptosis in colorectal carcinoma theoretical and therapeutic implications Aust N Z J Surg 69 1999 88 94
-
(1999)
Aust N Z J Surg
, vol.69
, pp. 88-94
-
-
Butler, L.M.1
Hewett, P.J.2
Fitridge, R.A.3
-
36
-
-
3242772301
-
Colon cancer: Genomics and apoptotic events
-
C. Rupnarain, Z. Dlamini, S. Naicker Colon cancer genomics and apoptotic events Biol Chem 385 2004 449 464
-
(2004)
Biol Chem
, vol.385
, pp. 449-464
-
-
Rupnarain, C.1
Dlamini, Z.2
Naicker, S.3
-
37
-
-
0035125747
-
Severe imbalance of cell proliferation and apoptosis in the left colon and in the rectosigmoid tract in subjects with a history of large adenomas
-
M. Anti, A. Armuzzi, S. Morini Severe imbalance of cell proliferation and apoptosis in the left colon and in the rectosigmoid tract in subjects with a history of large adenomas Gut 48 2001 238 246
-
(2001)
Gut
, vol.48
, pp. 238-246
-
-
Anti, M.1
Armuzzi, A.2
Morini, S.3
-
38
-
-
0028941441
-
Inhibition of apoptosis during development of colorectal cancer
-
A. Bedi, P.J. Pasricha, A.J. Akhtar Inhibition of apoptosis during development of colorectal cancer Cancer Res 55 1995 1811 1816
-
(1995)
Cancer Res
, vol.55
, pp. 1811-1816
-
-
Bedi, A.1
Pasricha, P.J.2
Akhtar, A.J.3
-
39
-
-
0035569891
-
Activation of c-MYC and c-MYB proto-oncogenes is associated with decreased apoptosis in tumor colon progression
-
C. Greco, S. Alvino, S. Buglioni Activation of c-MYC and c-MYB proto-oncogenes is associated with decreased apoptosis in tumor colon progression Anticancer Res 21 2001 3185 3192
-
(2001)
Anticancer Res
, vol.21
, pp. 3185-3192
-
-
Greco, C.1
Alvino, S.2
Buglioni, S.3
-
41
-
-
0030925132
-
Pathological and genetic correlates of apoptosis in the progression of colorectal neoplasia
-
N. Hawkins, J. Lees, R. Hargrave Pathological and genetic correlates of apoptosis in the progression of colorectal neoplasia Tumour Biol 18 1997 146 156
-
(1997)
Tumour Biol
, vol.18
, pp. 146-156
-
-
Hawkins, N.1
Lees, J.2
Hargrave, R.3
-
42
-
-
0029993271
-
Significance of spontaneous apoptosis during colorectal tumorigenesis
-
M. Koike Significance of spontaneous apoptosis during colorectal tumorigenesis J Surg Oncol 62 1996 97 108
-
(1996)
J Surg Oncol
, vol.62
, pp. 97-108
-
-
Koike, M.1
-
43
-
-
0033913693
-
Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict
-
J. O'Connell, M.W. Bennett, K. Nally Altered mechanisms of apoptosis in colon cancer Fas resistance and counterattack in the tumor-immune conflict Ann N Y Acad Sci 910 2000 178 192
-
(2000)
Ann N Y Acad Sci
, vol.910
, pp. 178-192
-
-
O'Connell, J.1
Bennett, M.W.2
Nally, K.3
-
44
-
-
14844288360
-
Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: Paving the road to patient-tailored therapy
-
C.M. Van Geelen, E.G. de Vries, S. de Jong Lessons from TRAIL-resistance mechanisms in colorectal cancer cells paving the road to patient-tailored therapy Drug Resist Updat 7 2004 345 358
-
(2004)
Drug Resist Updat
, vol.7
, pp. 345-358
-
-
Van Geelen, C.M.1
De Vries, E.G.2
De Jong, S.3
-
45
-
-
0025916387
-
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
-
N. Itoh, S. Yonehara, A. Ishii The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis Cell 66 1991 233 243
-
(1991)
Cell
, vol.66
, pp. 233-243
-
-
Itoh, N.1
Yonehara, S.2
Ishii, A.3
-
46
-
-
0031789409
-
Fas ligand expression in primary colon adenocarcinomas: Evidence that the Fas counterattack is a prevalent mechanism of immune evasion in human colon cancer
-
J. O'Connell, M.W. Bennett, G.C. O'Sullivan Fas ligand expression in primary colon adenocarcinomas evidence that the Fas counterattack is a prevalent mechanism of immune evasion in human colon cancer J Pathol 186 1998 240 246
-
(1998)
J Pathol
, vol.186
, pp. 240-246
-
-
O'Connell, J.1
Bennett, M.W.2
O'Sullivan, G.C.3
-
47
-
-
0028246885
-
Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium
-
P. Moller, K. Koretz, F. Leithauser Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium Int J Cancer 57 1994 371 377
-
(1994)
Int J Cancer
, vol.57
, pp. 371-377
-
-
Moller, P.1
Koretz, K.2
Leithauser, F.3
-
48
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
S.R. Wiley, K. Schooley, P.J. Smolak Identification and characterization of a new member of the TNF family that induces apoptosis Immunity 3 1995 673 682
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
-
49
-
-
0037672290
-
Expression of TRAIL (TNF-related apoptosis-inducing ligand) and its receptors in normal colonic mucosa, adenomas, and carcinomas
-
J.J. Koornstra, J.H. Kleibeuker, C.M. Van Geelen Expression of TRAIL (TNF-related apoptosis-inducing ligand) and its receptors in normal colonic mucosa, adenomas, and carcinomas J Pathol 200 2003 327 335
-
(2003)
J Pathol
, vol.200
, pp. 327-335
-
-
Koornstra, J.J.1
Kleibeuker, J.H.2
Van Geelen, C.M.3
-
50
-
-
0036898832
-
Expression of TRAIL and TRAIL receptors in colon carcinoma: TRAIL-R1 is an independent prognostic parameter
-
J. Strater, U. Hinz, H. Walczak Expression of TRAIL and TRAIL receptors in colon carcinoma TRAIL-R1 is an independent prognostic parameter Clin Cancer Res 8 2002 3734 3740
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3734-3740
-
-
Strater, J.1
Hinz, U.2
Walczak, H.3
-
51
-
-
0032530612
-
Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
-
T.S. Griffith, W.A. Chin, G.C. Jackson Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells J Immunol 161 1998 2833 2840
-
(1998)
J Immunol
, vol.161
, pp. 2833-2840
-
-
Griffith, T.S.1
Chin, W.A.2
Jackson, G.C.3
-
52
-
-
0036179391
-
TRAIL and its receptors in the colonic epithelium: A putative role in the defense of viral infections
-
J. Strater, H. Walczak, T. Pukrop TRAIL and its receptors in the colonic epithelium a putative role in the defense of viral infections Gastroenterology 122 2002 659 666
-
(2002)
Gastroenterology
, vol.122
, pp. 659-666
-
-
Strater, J.1
Walczak, H.2
Pukrop, T.3
-
53
-
-
0037148518
-
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development
-
K. Takeda, M.J. Smyth, E. Cretney Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development J Exp Med 195 2002 161 169
-
(2002)
J Exp Med
, vol.195
, pp. 161-169
-
-
Takeda, K.1
Smyth, M.J.2
Cretney, E.3
-
54
-
-
0033400418
-
Genetic pathways in colorectal and other cancers
-
M. Ilyas, J. Straub, I.P. Tomlinson Genetic pathways in colorectal and other cancers Eur J Cancer 35 1999 1986 2002
-
(1999)
Eur J Cancer
, vol.35
, pp. 1986-2002
-
-
Ilyas, M.1
Straub, J.2
Tomlinson, I.P.3
-
55
-
-
0036131142
-
Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
-
H. LeBlanc, D. Lawrence, E. Varfolomeev Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax Nat Med 8 2002 274 281
-
(2002)
Nat Med
, vol.8
, pp. 274-281
-
-
Leblanc, H.1
Lawrence, D.2
Varfolomeev, E.3
-
56
-
-
2342615480
-
X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells
-
J.M. Cummins, M. Kohli, C. Rago X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells Cancer Res 64 2004 3006 3008
-
(2004)
Cancer Res
, vol.64
, pp. 3006-3008
-
-
Cummins, J.M.1
Kohli, M.2
Rago, C.3
-
57
-
-
0035192884
-
FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis
-
A. Krueger, S. Baumann, P.H. Krammer FLICE-inhibitory proteins regulators of death receptor-mediated apoptosis Mol Cell Biol 21 2001 8247 8254
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8247-8254
-
-
Krueger, A.1
Baumann, S.2
Krammer, P.H.3
-
58
-
-
32544438637
-
c-FLIP inhibits chemotherapy-induced colorectal cancer cell death
-
[advance online publication].
-
Longley DB, Wilson TR, McEwan M, et al. c-FLIP inhibits chemotherapy-induced colorectal cancer cell death. Oncogene [advance online publication]. Available at: http://www.nature.com/onc/journal/vaop/ncurrent/abs/ 1209122a.html. Accessed January 9, 2005.
-
Oncogene
-
-
Longley, D.B.1
Wilson, T.R.2
McEwan, M.3
-
59
-
-
18744425429
-
The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways
-
T. Kataoka, R.C. Budd, N. Holler The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways Curr Biol 10 2000 640 648
-
(2000)
Curr Biol
, vol.10
, pp. 640-648
-
-
Kataoka, T.1
Budd, R.C.2
Holler, N.3
-
60
-
-
4544294745
-
Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling
-
M. Naito, R. Katayama, T. Ishioka Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling Mol Cell Biol 24 2004 8418 8427
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8418-8427
-
-
Naito, M.1
Katayama, R.2
Ishioka, T.3
-
61
-
-
0037075898
-
Activation of the p53 tumor suppressor protein
-
K.H. Vousden Activation of the p53 tumor suppressor protein Biochim Biophys Acta 1602 2002 47 59
-
(2002)
Biochim Biophys Acta
, vol.1602
, pp. 47-59
-
-
Vousden, K.H.1
-
62
-
-
0035367208
-
Mutations and allelic loss of p53 in primary tumor DNA from potentially cured patients with colorectal carcinoma
-
A. Forslund, C. Lonnroth, M. Andersson Mutations and allelic loss of p53 in primary tumor DNA from potentially cured patients with colorectal carcinoma J Clin Oncol 19 2001 2829 2836
-
(2001)
J Clin Oncol
, vol.19
, pp. 2829-2836
-
-
Forslund, A.1
Lonnroth, C.2
Andersson, M.3
-
63
-
-
0026523778
-
Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line
-
P. Shaw, R. Bovey, S. Tardy Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line Proc Natl Acad Sci USA 89 1992 4495 4499
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4495-4499
-
-
Shaw, P.1
Bovey, R.2
Tardy, S.3
-
64
-
-
12644253829
-
Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas
-
A. Fazeli, R.G. Steen, S.L. Dickinson Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas Proc Natl Acad Sci USA 94 1997 10199 10204
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10199-10204
-
-
Fazeli, A.1
Steen, R.G.2
Dickinson, S.L.3
-
65
-
-
0037162833
-
Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization
-
P. Lassus, X. Opitz-Araya, Y. Lazebnik Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization Science 297 2002 1352 1354
-
(2002)
Science
, vol.297
, pp. 1352-1354
-
-
Lassus, P.1
Opitz-Araya, X.2
Lazebnik, Y.3
-
66
-
-
0037380598
-
Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells
-
M. Jiang, J. Milner Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells Genes Dev 17 2003 832 837
-
(2003)
Genes Dev
, vol.17
, pp. 832-837
-
-
Jiang, M.1
Milner, J.2
-
67
-
-
0033844202
-
Immunohistochemical expression of bcl-2 and p53 oncoproteins: Correlation with Ki67 proliferation index and prognostic histopathologic parameters in colorectal neoplasia
-
H.A. Saleh, H. Jackson, M. Banerjee Immunohistochemical expression of bcl-2 and p53 oncoproteins correlation with Ki67 proliferation index and prognostic histopathologic parameters in colorectal neoplasia Appl Immunohistochem Mol Morphol 8 2000 175 182
-
(2000)
Appl Immunohistochem Mol Morphol
, vol.8
, pp. 175-182
-
-
Saleh, H.A.1
Jackson, H.2
Banerjee, M.3
-
68
-
-
0036479115
-
Transcriptional repression of the anti-apoptotic survivin gene by wild type p53
-
W.H. Hoffman, S. Biade, J.T. Zilfou Transcriptional repression of the anti-apoptotic survivin gene by wild type p53 J Biol Chem 277 2002 3247 3257
-
(2002)
J Biol Chem
, vol.277
, pp. 3247-3257
-
-
Hoffman, W.H.1
Biade, S.2
Zilfou, J.T.3
-
69
-
-
0035496104
-
APC, signal transduction and genetic instability in colorectal cancer
-
R. Fodde, R. Smits, H. Clevers APC, signal transduction and genetic instability in colorectal cancer Nat Rev Cancer 1 2001 55 67
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 55-67
-
-
Fodde, R.1
Smits, R.2
Clevers, H.3
-
70
-
-
25144460654
-
Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional gene
-
T. Senda, A. Shimomura, A. Iizuka-Kogo Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional gene Anat Sci Int 80 2005 121 131
-
(2005)
Anat Sci Int
, vol.80
, pp. 121-131
-
-
Senda, T.1
Shimomura, A.2
Iizuka-Kogo, A.3
-
71
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
T.C. He, A.B. Sparks, C. Rago Identification of c-MYC as a target of the APC pathway Science 281 1998 1509 1512
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
-
72
-
-
0029945789
-
Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas
-
M. Krajewska, S.F. Moss, S. Krajewski Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas Cancer Res 56 1996 2422 2427
-
(1996)
Cancer Res
, vol.56
, pp. 2422-2427
-
-
Krajewska, M.1
Moss, S.F.2
Krajewski, S.3
-
73
-
-
0029869360
-
Evidence of reciprocity of bcl-2 and p53 expression in human colorectal adenomas and carcinomas
-
A.J. Watson, A.J. Merritt, L.S. Jones Evidence of reciprocity of bcl-2 and p53 expression in human colorectal adenomas and carcinomas Br J Cancer 73 1996 889 895
-
(1996)
Br J Cancer
, vol.73
, pp. 889-895
-
-
Watson, A.J.1
Merritt, A.J.2
Jones, L.S.3
-
74
-
-
0344348993
-
Analysis of the p53/BAX pathway in colorectal cancer: Low BAX is a negative prognostic factor in patients with resected liver metastases
-
I. Sturm, C.H. Kohne, G. Wolff Analysis of the p53/BAX pathway in colorectal cancer low BAX is a negative prognostic factor in patients with resected liver metastases J Clin Oncol 17 1999 1364 1374
-
(1999)
J Clin Oncol
, vol.17
, pp. 1364-1374
-
-
Sturm, I.1
Kohne, C.H.2
Wolff, G.3
-
75
-
-
0034602188
-
Role of BAX in the apoptotic response to anticancer agents
-
L. Zhang, J. Yu, B.H. Park Role of BAX in the apoptotic response to anticancer agents Science 290 2000 989 992
-
(2000)
Science
, vol.290
, pp. 989-992
-
-
Zhang, L.1
Yu, J.2
Park, B.H.3
-
76
-
-
0036533524
-
Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status
-
S. Violette, L. Poulain, E. Dussaulx Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status Int J Cancer 98 2002 498 504
-
(2002)
Int J Cancer
, vol.98
, pp. 498-504
-
-
Violette, S.1
Poulain, L.2
Dussaulx, E.3
-
77
-
-
0037085935
-
Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: Synergism with sulindac-mediated inhibition of Bcl-x(L)
-
R. Ravi, A. Bedi Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers synergism with sulindac-mediated inhibition of Bcl-x(L) Cancer Res 62 2002 1583 1587
-
(2002)
Cancer Res
, vol.62
, pp. 1583-1587
-
-
Ravi, R.1
Bedi, A.2
-
78
-
-
0035070248
-
Transcriptional regulation of the bcl-x gene encoding the anti-apoptotic Bcl-xL protein by Ets, Rel/NFkappaB, STAT and AP1 transcription factor families
-
L. Sevilla, A. Zaldumbide, P. Pognonec Transcriptional regulation of the bcl-x gene encoding the anti-apoptotic Bcl-xL protein by Ets, Rel/NFkappaB, STAT and AP1 transcription factor families Histol Histopathol 16 2001 595 601
-
(2001)
Histol Histopathol
, vol.16
, pp. 595-601
-
-
Sevilla, L.1
Zaldumbide, A.2
Pognonec, P.3
-
79
-
-
1542649570
-
Overcoming antiapoptotic responses to promote chemosensitivity in metastatic colorectal cancer to the liver
-
J.C. Cusack Jr Overcoming antiapoptotic responses to promote chemosensitivity in metastatic colorectal cancer to the liver Ann Surg Oncol 10 2003 852 862
-
(2003)
Ann Surg Oncol
, vol.10
, pp. 852-862
-
-
Cusack Jr., J.C.1
-
80
-
-
0032533494
-
Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer
-
H. Kawasaki, D.C. Altieri, C.D. Lu Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer Cancer Res 58 1998 5071 5074
-
(1998)
Cancer Res
, vol.58
, pp. 5071-5074
-
-
Kawasaki, H.1
Altieri, D.C.2
Lu, C.D.3
-
81
-
-
0037343270
-
Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference
-
N.S. Williams, R.B. Gaynor, S. Scoggin Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference Clin Cancer Res 9 2003 931 946
-
(2003)
Clin Cancer Res
, vol.9
, pp. 931-946
-
-
Williams, N.S.1
Gaynor, R.B.2
Scoggin, S.3
-
82
-
-
0035011885
-
Immunohistochemical detection of the anti-apoptosis protein, survivin, predicts survival after curative resection of stage II colorectal carcinomas
-
A.I. Sarela, N. Scott, J. Ramsdale Immunohistochemical detection of the anti-apoptosis protein, survivin, predicts survival after curative resection of stage II colorectal carcinomas Ann Surg Oncol 8 2001 305 310
-
(2001)
Ann Surg Oncol
, vol.8
, pp. 305-310
-
-
Sarela, A.I.1
Scott, N.2
Ramsdale, J.3
-
83
-
-
0033578879
-
Sulindac inhibits activation of the NF-kappaB pathway
-
Y. Yamamoto, M.J. Yin, K.M. Lin Sulindac inhibits activation of the NF-kappaB pathway J Biol Chem 274 1999 27307 27314
-
(1999)
J Biol Chem
, vol.274
, pp. 27307-27314
-
-
Yamamoto, Y.1
Yin, M.J.2
Lin, K.M.3
-
84
-
-
1642539021
-
The chemopreventive agent sulindac attenuates expression of the antiapoptotic protein survivin in colorectal carcinoma cells
-
T. Zhang, J.Z. Fields, S.M. Ehrlich The chemopreventive agent sulindac attenuates expression of the antiapoptotic protein survivin in colorectal carcinoma cells J Pharmacol Exp Ther 308 2004 434 437
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 434-437
-
-
Zhang, T.1
Fields, J.Z.2
Ehrlich, S.M.3
-
85
-
-
24944473232
-
Oxaliplatin, a potent inhibitor of survivin, enhances paclitaxel-induced apoptosis and mitotic catastrophe in colon cancer cells
-
Y. Fujie, H. Yamamoto, C.Y. Ngan Oxaliplatin, a potent inhibitor of survivin, enhances paclitaxel-induced apoptosis and mitotic catastrophe in colon cancer cells Jpn J Clin Oncol 35 2005 453 463
-
(2005)
Jpn J Clin Oncol
, vol.35
, pp. 453-463
-
-
Fujie, Y.1
Yamamoto, H.2
Ngan, C.Y.3
-
86
-
-
23844434673
-
AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cells
-
A. Urbano, U. Lakshmanan, P.H. Choo AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cells EMBO J 24 2005 2815 2826
-
(2005)
EMBO J
, vol.24
, pp. 2815-2826
-
-
Urbano, A.1
Lakshmanan, U.2
Choo, P.H.3
-
87
-
-
31844435395
-
Tetracycline analogues (doxycycline and COL-3) induce caspase-dependent and -independent apoptosis in human colon cancer cells
-
T. Onoda, T. Ono, D.K. Dhar Tetracycline analogues (doxycycline and COL-3) induce caspase-dependent and -independent apoptosis in human colon cancer cells Int J Cancer 118 2005 in press
-
(2005)
Int J Cancer
, vol.118
-
-
Onoda, T.1
Ono, T.2
Dhar, D.K.3
-
88
-
-
23144445839
-
Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells
-
Y.C. Park, J.H. Jeong, K.J. Park Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells Life Sci 77 2005 2059 2070
-
(2005)
Life Sci
, vol.77
, pp. 2059-2070
-
-
Park, Y.C.1
Jeong, J.H.2
Park, K.J.3
-
89
-
-
21244502193
-
Flavone initiates a hierarchical activation of the caspase-cascade in colon cancer cells
-
L.M. Erhart, B. Lankat-Buttgereit, H. Schmidt Flavone initiates a hierarchical activation of the caspase-cascade in colon cancer cells Apoptosis 10 2005 611 617
-
(2005)
Apoptosis
, vol.10
, pp. 611-617
-
-
Erhart, L.M.1
Lankat-Buttgereit, B.2
Schmidt, H.3
-
90
-
-
0032411879
-
Stress signals for apoptosis: Ceramide and c-Jun kinase
-
S. Basu, R. Kolesnick Stress signals for apoptosis ceramide and c-Jun kinase Oncogene 17 1998 3277 3285
-
(1998)
Oncogene
, vol.17
, pp. 3277-3285
-
-
Basu, S.1
Kolesnick, R.2
-
91
-
-
0029761340
-
Accumulation of glucosylceramides in multidrug-resistant cancer cells
-
Y. Lavie, H. Cao, S.L. Bursten Accumulation of glucosylceramides in multidrug-resistant cancer cells J Biol Chem 271 1996 19530 19536
-
(1996)
J Biol Chem
, vol.271
, pp. 19530-19536
-
-
Lavie, Y.1
Cao, H.2
Bursten, S.L.3
-
92
-
-
0037214386
-
Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway
-
F.M. Ruemmele, S. Schwartz, E.G. Seidman Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway Gut 52 2003 94 100
-
(2003)
Gut
, vol.52
, pp. 94-100
-
-
Ruemmele, F.M.1
Schwartz, S.2
Seidman, E.G.3
-
93
-
-
6444242600
-
Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells
-
Y.H. Kim, J.W. Park, J.Y. Lee Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells Carcinogenesis 25 2004 1813 1820
-
(2004)
Carcinogenesis
, vol.25
, pp. 1813-1820
-
-
Kim, Y.H.1
Park, J.W.2
Lee, J.Y.3
-
94
-
-
0036133885
-
Tributyrin-induced differentiation promotes apoptosis of LS 174T colon cancer cells in vitro
-
C.P. Schroder, H.R. Maurer Tributyrin-induced differentiation promotes apoptosis of LS 174T colon cancer cells in vitro Int J Oncol 20 2002 195 200
-
(2002)
Int J Oncol
, vol.20
, pp. 195-200
-
-
Schroder, C.P.1
Maurer, H.R.2
-
95
-
-
0032817625
-
Interleukin 1 and interleukin 1beta converting enzyme (caspase 1) expression in the human colonic epithelial barrier. Caspase 1 downregulation in colon cancer
-
A. Jarry, G. Vallette, E. Cassagnau Interleukin 1 and interleukin 1beta converting enzyme (caspase 1) expression in the human colonic epithelial barrier. Caspase 1 downregulation in colon cancer Gut 45 1999 246 251
-
(1999)
Gut
, vol.45
, pp. 246-251
-
-
Jarry, A.1
Vallette, G.2
Cassagnau, E.3
-
96
-
-
0042692791
-
The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells
-
I. Shureiqi, W. Jiang, X. Zuo The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells Proc Natl Acad Sci USA 100 2003 9968 9973
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9968-9973
-
-
Shureiqi, I.1
Jiang, W.2
Zuo, X.3
-
97
-
-
0038543824
-
Chemoprevention of colorectal cancer
-
P.A. Janne, R.J. Mayer Chemoprevention of colorectal cancer N Engl J Med 342 2000 1960 1968
-
(2000)
N Engl J Med
, vol.342
, pp. 1960-1968
-
-
Janne, P.A.1
Mayer, R.J.2
-
98
-
-
0033004686
-
Role of telomerase in cellular proliferation and cancer
-
S.E. Holt, J.W. Shay Role of telomerase in cellular proliferation and cancer J Cell Physiol 180 1999 10 18
-
(1999)
J Cell Physiol
, vol.180
, pp. 10-18
-
-
Holt, S.E.1
Shay, J.W.2
-
99
-
-
0031750443
-
Antisense telomerase treatment: Induction of two distinct pathways, apoptosis and differentiation
-
S. Kondo, Y. Tanaka, Y. Kondo Antisense telomerase treatment induction of two distinct pathways, apoptosis and differentiation FASEB J 12 1998 801 811
-
(1998)
FASEB J
, vol.12
, pp. 801-811
-
-
Kondo, S.1
Tanaka, Y.2
Kondo, Y.3
-
100
-
-
0036678137
-
Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression
-
Y. Kakugawa, T. Wada, K. Yamaguchi Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression Proc Natl Acad Sci USA 99 2002 10718 10723
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10718-10723
-
-
Kakugawa, Y.1
Wada, T.2
Yamaguchi, K.3
-
101
-
-
5144230475
-
Nitric oxide signaling in colon cancer chemoprevention
-
C.V. Rao Nitric oxide signaling in colon cancer chemoprevention Mutat Res 555 2004 107 119
-
(2004)
Mutat Res
, vol.555
, pp. 107-119
-
-
Rao, C.V.1
-
102
-
-
0036209688
-
Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases
-
H.H. Backus, C.J. Van Groeningen, W. Vos Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases J Clin Pathol 55 2002 206 211
-
(2002)
J Clin Pathol
, vol.55
, pp. 206-211
-
-
Backus, H.H.1
Van Groeningen, C.J.2
Vos, W.3
-
103
-
-
0032982834
-
FasL is more frequently expressed in liver metastases of colorectal cancer than in matched primary carcinomas
-
B. Mann, A. Gratchev, C. Bohm FasL is more frequently expressed in liver metastases of colorectal cancer than in matched primary carcinomas Br J Cancer 79 1999 1262 1269
-
(1999)
Br J Cancer
, vol.79
, pp. 1262-1269
-
-
Mann, B.1
Gratchev, A.2
Bohm, C.3
|