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Volumn 13, Issue 6, 2006, Pages 1003-1016

p53 in recombination and repair

Author keywords

Excision repair; Homologous recombination; Mismatch repair; Nonhomologous end joining; Topoisomerase I

Indexed keywords

CYCLIN DEPENDENT KINASE; DNA TOPOISOMERASE; DOUBLE STRANDED RNA; GENE PRODUCT; PROTEIN 14 3 3; PROTEIN MSH2; PROTEIN P53; RAD51 PROTEIN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

EID: 33644927601     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401903     Document Type: Review
Times cited : (190)

References (174)
  • 2
    • 0026579237 scopus 로고
    • TP53 tumor suppressor gene: A model for investigating human mutagenesis
    • deFromentel C and Soussi T (1992) TP53 tumor suppressor gene: A model for investigating human mutagenesis. Genes Chromosomes Cancer 4: 1-15.
    • (1992) Genes Chromosomes Cancer , vol.4 , pp. 1-15
    • deFromentel, C.1    Soussi, T.2
  • 3
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • Lane DP (1992) p53, guardian of the genome. Nature 358: 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 4
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ (1997) p53, the cellular gatekeeper for growth and division. Cell 88: 323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 6
    • 0030761351 scopus 로고    scopus 로고
    • ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase
    • Vaziri H, West MD, Allsopp RC, Davison TS, Wu YS, Arrowsmith CH, Poirier GG and Benchimol S (1997) ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. EMBO J. 16: 6018-6033.
    • (1997) EMBO J. , vol.16 , pp. 6018-6033
    • Vaziri, H.1    West, M.D.2    Allsopp, R.C.3    Davison, T.S.4    Wu, Y.S.5    Arrowsmith, C.H.6    Poirier, G.G.7    Benchimol, S.8
  • 7
    • 0032481112 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation is required for p53-dependent signal transduction induced by radiation
    • Wang X, Ohnishi K, Takahashi A and Ohnishi T (1998) Poly(ADP-ribosyl)ation is required for p53-dependent signal transduction induced by radiation. Oncogene 17: 2819-2825.
    • (1998) Oncogene , vol.17 , pp. 2819-2825
    • Wang, X.1    Ohnishi, K.2    Takahashi, A.3    Ohnishi, T.4
  • 8
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wildtype p53
    • Livingstone LR, White A, Sprouse J, Livanos E, Jacks T and Tlsty TD (1992) Altered cell cycle arrest and gene amplification potential accompany loss of wildtype p53. Cell 70: 923-935.
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 11
    • 0033032590 scopus 로고    scopus 로고
    • The effect of functional inactivation of TP53 by HPV-E6 transformation on the induction of chromosome aberrations by gamma rays in human tumor cells
    • Schwartz JL and Russell KJ (1999) The effect of functional inactivation of TP53 by HPV-E6 transformation on the induction of chromosome aberrations by gamma rays in human tumor cells. Radiat. Res. 151: 385-390.
    • (1999) Radiat. Res. , vol.151 , pp. 385-390
    • Schwartz, J.L.1    Russell, K.J.2
  • 14
    • 0029055808 scopus 로고
    • Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus
    • Jayaraman J and Prives C (1995) Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus. Cell 81: 1021-1029.
    • (1995) Cell , vol.81 , pp. 1021-1029
    • Jayaraman, J.1    Prives, C.2
  • 15
    • 0029013273 scopus 로고
    • p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches
    • Lee S, Elenbaas B, Levine A and Griffith J (1995) p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/ deletion mismatches. Cell 81: 1013-1020.
    • (1995) Cell , vol.81 , pp. 1013-1020
    • Lee, S.1    Elenbaas, B.2    Levine, A.3    Griffith, J.4
  • 17
    • 0027284915 scopus 로고
    • p53-catalyzed annealing of complementary single-stranded nucleic adds
    • Oberosler P, Hloch P, Ramsperger U and Stahl H (1993) p53-catalyzed annealing of complementary single-stranded nucleic adds. EMBO J. 12: 2389-2396.
    • (1993) EMBO J. , vol.12 , pp. 2389-2396
    • Oberosler, P.1    Hloch, P.2    Ramsperger, U.3    Stahl, H.4
  • 18
    • 0028228913 scopus 로고
    • Human p53 directs DNA strand reassociation and is photolabelled by 8-azido ATP
    • Brain R and Jenkins JR (1994) Human p53 directs DNA strand reassociation and is photolabelled by 8-azido ATP. Oncogene 9: 1775-1780.
    • (1994) Oncogene , vol.9 , pp. 1775-1780
    • Brain, R.1    Jenkins, J.R.2
  • 20
    • 0030985675 scopus 로고    scopus 로고
    • Human p53 binds Holliday junctions strongly and facilitates their cleavage
    • Lee S, Cavallo L and Griffith J (1997) Human p53 binds Holliday junctions strongly and facilitates their cleavage. J. Biol. Chem. 272: 7532-7539.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7532-7539
    • Lee, S.1    Cavallo, L.2    Griffith, J.3
  • 21
    • 0031865231 scopus 로고    scopus 로고
    • Dissociation of the recombination control and the sequence-specific transactivation function of p53
    • Dudenhöffer C, Kurth M, Janus F, Deppert W and Wiesmüller L (1998) Dissociation of the recombination control and the sequence-specific transactivation function of p53. Mol. Cell. Biol. 18: 5332-5342.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5332-5342
    • Dudenhöffer, C.1    Kurth, M.2    Janus, F.3    Deppert, W.4    Wiesmüller, L.5
  • 22
    • 0037192694 scopus 로고    scopus 로고
    • p53 and recombination intermediates: Role of tetramerization at DNA junctions in complex formation and exonucleolytic degradation
    • Janz C, Süsse S and Wiesmüller L (2002) p53 and recombination intermediates: Role of tetramerization at DNA junctions in complex formation and exonucleolytic degradation. Oncogene 21: 2130-2140.
    • (2002) Oncogene , vol.21 , pp. 2130-2140
    • Janz, C.1    Süsse, S.2    Wiesmüller, L.3
  • 24
    • 0032560817 scopus 로고    scopus 로고
    • Excision of mismatched nucleotides from DNA: A potential mechanism for enhancing DNA replication fidelity by the wildtype p53 protein
    • Huang P (1998) Excision of mismatched nucleotides from DNA: A potential mechanism for enhancing DNA replication fidelity by the wildtype p53 protein. Oncogene 17: 261-270.
    • (1998) Oncogene , vol.17 , pp. 261-270
    • Huang, P.1
  • 25
    • 0033019052 scopus 로고    scopus 로고
    • Different regulation of the core domain activities 3′ to 5′ exonuclease and sequence-specific DNA binding
    • Janus F, Albrechtsen N, Knippschild U, Wiesmüller L, Grosse F and Deppert W (1999) Different regulation of the core domain activities 3′ to 5′ exonuclease and sequence-specific DNA binding. Mol. Cell. Biol. 19: 2155-2168.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2155-2168
    • Janus, F.1    Albrechtsen, N.2    Knippschild, U.3    Wiesmüller, L.4    Grosse, F.5    Deppert, W.6
  • 26
    • 0034612585 scopus 로고    scopus 로고
    • Substrate specificity of the p53-associated 3′-5′ exonuclease
    • Skalski V, Lin ZY, Choi BY and Brown KR (2000) Substrate specificity of the p53-associated 3′-5′ exonuclease. Oncogene 19: 3321-3329.
    • (2000) Oncogene , vol.19 , pp. 3321-3329
    • Skalski, V.1    Lin, Z.Y.2    Choi, B.Y.3    Brown, K.R.4
  • 27
    • 0034850266 scopus 로고    scopus 로고
    • Exonucleolytic proofreading by p53 protein
    • Bakhanashvili M (2001) Exonucleolytic proofreading by p53 protein. Eur. J. Biochem. 268: 2047-2054.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 2047-2054
    • Bakhanashvili, M.1
  • 29
    • 0036529624 scopus 로고    scopus 로고
    • Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase alpha-primase
    • Melle C and Nasheuer HP (2002) Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase alpha-primase. Nucleic Acids Res. 30: 1493-1499.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1493-1499
    • Melle, C.1    Nasheuer, H.P.2
  • 30
    • 0033554592 scopus 로고    scopus 로고
    • Dissociation of the recombination control and the sequence-specific transactivation function of p53
    • Dudenhöffer C, Rohaly G, Will K, Deppert W and Wiesmüller L (1999) Dissociation of the recombination control and the sequence-specific transactivation function of p53. Oncogene 18: 5773-5784.
    • (1999) Oncogene , vol.18 , pp. 5773-5784
    • Dudenhöffer, C.1    Rohaly, G.2    Will, K.3    Deppert, W.4    Wiesmüller, L.5
  • 31
    • 0033552636 scopus 로고    scopus 로고
    • Maintenance of genomic integrity by p53: Complementary roles for activated and non-activated p53
    • Albrechtsen N, Domreiter I, Grosse F, Kim E, Wiesmuller L and Deppert W (1999) Maintenance of genomic integrity by p53: Complementary roles for activated and non-activated p53. Oncogene 18: 7706-7717.
    • (1999) Oncogene , vol.18 , pp. 7706-7717
    • Albrechtsen, N.1    Domreiter, I.2    Grosse, F.3    Kim, E.4    Wiesmuller, L.5    Deppert, W.6
  • 32
    • 2442477786 scopus 로고    scopus 로고
    • P53's double life: Transactivation-independent repression of homologous recombination
    • Bertrand P, Saintigny Y and Lopez BS (2004) P53's double life: transactivation-independent repression of homologous recombination. Trends Genet. 20: 235-243.
    • (2004) Trends Genet. , vol.20 , pp. 235-243
    • Bertrand, P.1    Saintigny, Y.2    Lopez, B.S.3
  • 33
    • 11244344381 scopus 로고    scopus 로고
    • p53: Traffic cop at the crossroads of DNA repair and recombination
    • Sengupta S and Harris CC (2005) p53: Traffic cop at the crossroads of DNA repair and recombination. Nat. Rev. Mol. Cell Biol. 6: 44-55.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 44-55
    • Sengupta, S.1    Harris, C.C.2
  • 36
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapoptotic gene, is induced by p53
    • Nakano K and Vousden KH (2001) PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 7: 683-694.
    • (2001) Mol. Cell , vol.7 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 37
    • 1342328146 scopus 로고    scopus 로고
    • p53 in the cytoplasm: A question of overkill?
    • Baptiste N and Prives C (2004) p53 in the cytoplasm: A question of overkill? Cell 116: 487-489.
    • (2004) Cell , vol.116 , pp. 487-489
    • Baptiste, N.1    Prives, C.2
  • 38
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers JHJ (2001) Genome maintenance mechanisms for preventing cancer. Nature 411: 366-373.
    • (2001) Nature , vol.411 , pp. 366-373
    • Hoeijmakers, J.H.J.1
  • 39
    • 0042872991 scopus 로고    scopus 로고
    • Chemistry and biology of DNA repair
    • Schärer OD (2003) Chemistry and biology of DNA repair. Angew. Chem. Int. Ed. Engl. 42: 2946-2974.
    • (2003) Angew. Chem. Int. Ed. Engl. , vol.42 , pp. 2946-2974
    • Schärer, O.D.1
  • 40
    • 0029029741 scopus 로고
    • Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance
    • Ford JM and Hanawalt PC (1995) Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance. Proc. Natl. Acad. Sci. USA 92: 8876-8880.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8876-8880
    • Ford, J.M.1    Hanawalt, P.C.2
  • 41
    • 0034646620 scopus 로고    scopus 로고
    • Decreased DNA repair efficiency by loss or disruption of p53 function preferentially affects removal of cyclobutane pyrimidine dimers from non-transcribed strand and slow repair sites in transcribed strand
    • Zhu Q, Wani MA, El-Mahdy M and Wani AA (2000) Decreased DNA repair efficiency by loss or disruption of p53 function preferentially affects removal of cyclobutane pyrimidine dimers from non-transcribed strand and slow repair sites in transcribed strand. J. Biol. Chem. 275: 11492-11497.
    • (2000) J. Biol. Chem. , vol.275 , pp. 11492-11497
    • Zhu, Q.1    Wani, M.A.2    El-Mahdy, M.3    Wani, A.A.4
  • 42
    • 0000516293 scopus 로고    scopus 로고
    • Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair
    • Huang BJ, Ford JM, Hanawalt PC and Chu G (1999) Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair. Proc. Natl. Acad. Sci. USA 96: 424-428.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 424-428
    • Huang, B.J.1    Ford, J.M.2    Hanawalt, P.C.3    Chu, G.4
  • 43
    • 0036791008 scopus 로고    scopus 로고
    • p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene
    • Adimoolam S and Ford JM (2002) p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene. Proc. Natl. Acad. Sci. USA 99: 12985-12990.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12985-12990
    • Adimoolam, S.1    Ford, J.M.2
  • 44
    • 0036234458 scopus 로고    scopus 로고
    • p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice
    • Tan T and Chu G (2002) p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice. Mol. Cell. Biol. 22: 3247-3254.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3247-3254
    • Tan, T.1    Chu, G.2
  • 45
    • 0036490207 scopus 로고    scopus 로고
    • A nucleotide excision repair master-switch: p53 regulated coordinate induction of global genomic repair genes
    • Amundson SA, Patterson A, Do KT and Fornace Jr AJ (2002) A nucleotide excision repair master-switch: P53 regulated coordinate induction of global genomic repair genes. Cancer Biol. Ther. 1: 145-149.
    • (2002) Cancer Biol. Ther. , vol.1 , pp. 145-149
    • Amundson, S.A.1    Patterson, A.2    Do, K.T.3    Fornace Jr., A.J.4
  • 46
    • 0032818868 scopus 로고    scopus 로고
    • Potential roles for p53 in nucleotide excision repair
    • McKay BC, Ljungman M and Rainbow AJ (1999) Potential roles for p53 in nucleotide excision repair. Carcinogenesis 20: 1389-1396.
    • (1999) Carcinogenesis , vol.20 , pp. 1389-1396
    • McKay, B.C.1    Ljungman, M.2    Rainbow, A.J.3
  • 50
    • 0036261733 scopus 로고    scopus 로고
    • BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets
    • MacLachlan TK, Takimoto R and El-Deiry WS (2002) BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets. Mol. Cell. Biol. 22: 4280-4292.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4280-4292
    • MacLachlan, T.K.1    Takimoto, R.2    El-Deiry, W.S.3
  • 51
    • 0042379999 scopus 로고    scopus 로고
    • p53 and regulation of DNA damage recognition during nucleotide excision repair
    • Adimoolam S and Ford JM (2003) p53 and regulation of DNA damage recognition during nucleotide excision repair. DNA Repair 2: 947-954.
    • (2003) DNA Repair , vol.2 , pp. 947-954
    • Adimoolam, S.1    Ford, J.M.2
  • 53
    • 0037169354 scopus 로고    scopus 로고
    • Cancer susceptibility and the functions of BRCA1 and BRCA2
    • Venkitaraman AR (2002) Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 108: 171-182.
    • (2002) Cell , vol.108 , pp. 171-182
    • Venkitaraman, A.R.1
  • 54
    • 0029670607 scopus 로고    scopus 로고
    • Induction of murine O6-alkylguanine-DNA-alkyltransferase in response to ionising radiation is p53 gene dose dependent
    • Rafferty JA, Clarke AR, Sellappan D, Koref MS, Frayling IM and Margison GP (1996) Induction of murine O6-alkylguanine-DNA-alkyltransferase in response to ionising radiation is p53 gene dose dependent. Oncogene 12: 693-697.
    • (1996) Oncogene , vol.12 , pp. 693-697
    • Rafferty, J.A.1    Clarke, A.R.2    Sellappan, D.3    Koref, M.S.4    Frayling, I.M.5    Margison, G.P.6
  • 55
    • 0032552021 scopus 로고    scopus 로고
    • p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents
    • Grombacher T, Eichhorn U and Kaina B (1998) p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents. Oncogene 17: 845-851.
    • (1998) Oncogene , vol.17 , pp. 845-851
    • Grombacher, T.1    Eichhorn, U.2    Kaina, B.3
  • 56
    • 10944251591 scopus 로고    scopus 로고
    • Repair and genetic consequences of endogenous DNA base damage in mammalian cells
    • Barnes DE and Lindahl T (2004) Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annu. Rev. Genet. 38: 445-476.
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 445-476
    • Barnes, D.E.1    Lindahl, T.2
  • 58
    • 14644401653 scopus 로고    scopus 로고
    • Homeostatic regulation of base excision repair by a p53-induced phosphatase: Linking stress response pathways with DNA repair proteins
    • Lu X, Nguyen TA, Appella E and Donehower LA (2004) Homeostatic regulation of base excision repair by a p53-induced phosphatase: Linking stress response pathways with DNA repair proteins. Cell Cycle 3: 1363-1366.
    • (2004) Cell Cycle , vol.3 , pp. 1363-1366
    • Lu, X.1    Nguyen, T.A.2    Appella, E.3    Donehower, L.A.4
  • 60
    • 0035920118 scopus 로고    scopus 로고
    • Identification of a p53 response element in the promoter region of the hMSH2 gene required for expression in A2780 ovarian cancer cells
    • Warnick CT, Dabbas B, Ford CD and Strait KA (2001) Identification of a p53 response element in the promoter region of the hMSH2 gene required for expression in A2780 ovarian cancer cells. J. Biol. Chem. 276: 27363-27370.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27363-27370
    • Warnick, C.T.1    Dabbas, B.2    Ford, C.D.3    Strait, K.A.4
  • 61
    • 16344393332 scopus 로고    scopus 로고
    • Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements
    • Chen J and Sadowski I (2005) Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements. Proc. Natl. Acad. Sci. USA 102: 4813-4818.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 4813-4818
    • Chen, J.1    Sadowski, I.2
  • 62
    • 0033776758 scopus 로고    scopus 로고
    • Roles for mismatch repair factors in regulating genetic recombination
    • Evans E and Alani E (2000) Roles for mismatch repair factors in regulating genetic recombination. Mol. Cell. Biol. 20: 7839-7844.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7839-7844
    • Evans, E.1    Alani, E.2
  • 63
    • 0036198664 scopus 로고    scopus 로고
    • DNA mismatch repair and mutation avoidance pathways
    • Marti TM, Kunz C and Fleck O (2002) DNA mismatch repair and mutation avoidance pathways. J. Cell. Physiol. 191: 28-41.
    • (2002) J. Cell. Physiol. , vol.191 , pp. 28-41
    • Marti, T.M.1    Kunz, C.2    Fleck, O.3
  • 65
    • 3242885728 scopus 로고    scopus 로고
    • Mismatch repair and DNA damage signalling
    • Stojic L, Brun R and Jiricny J (2004) Mismatch repair and DNA damage signalling. DNA Repair 3: 1091-1101.
    • (2004) DNA Repair , vol.3 , pp. 1091-1101
    • Stojic, L.1    Brun, R.2    Jiricny, J.3
  • 67
    • 0032560473 scopus 로고    scopus 로고
    • KARP-1 is induced by DNA damage in a p53- and ataxia telangiectasia mutated-dependent fashion
    • Myung K, Braastad C, He DM and Hendrickson E (1998) KARP-1 is induced by DNA damage in a p53- and ataxia telangiectasia mutated-dependent fashion. Proc. Natl. Acad. Sci. USA 95: 7664-7669.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7664-7669
    • Myung, K.1    Braastad, C.2    He, D.M.3    Hendrickson, E.4
  • 68
    • 0028919069 scopus 로고
    • Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage
    • Smith ML, Chen IT, Zhan Q, O'Connor PM and Fornace Jr AJ (1995) Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage. Oncogene 10: 1053-1059.
    • (1995) Oncogene , vol.10 , pp. 1053-1059
    • Smith, M.L.1    Chen, I.T.2    Zhan, Q.3    O'Connor, P.M.4    Fornace Jr., A.J.5
  • 70
    • 0029880959 scopus 로고    scopus 로고
    • Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations
    • Leveillard T, Andera L, Bissonnette N, Schaeffer L, Bracco L, Egly JM and Wasylyk B (1996) Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations. EMBO J. 15: 1615-1624.
    • (1996) EMBO J. , vol.15 , pp. 1615-1624
    • Leveillard, T.1    Andera, L.2    Bissonnette, N.3    Schaeffer, L.4    Bracco, L.5    Egly, J.M.6    Wasylyk, B.7
  • 71
    • 0037450761 scopus 로고    scopus 로고
    • p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage
    • Rubbi CP and Milner J (2003) p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage. EMBO J. 22: 975-986.
    • (2003) EMBO J. , vol.22 , pp. 975-986
    • Rubbi, C.P.1    Milner, J.2
  • 72
    • 0032894008 scopus 로고    scopus 로고
    • Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery
    • Offer H, Wolkowicz R, Mates D, Blumenstein S, Livneh Z and Rotter V (1999) Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery. FEBS Lett. 450: 197-204.
    • (1999) FEBS Lett. , vol.450 , pp. 197-204
    • Offer, H.1    Wolkowicz, R.2    Mates, D.3    Blumenstein, S.4    Livneh, Z.5    Rotter, V.6
  • 74
    • 0036317093 scopus 로고    scopus 로고
    • The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA
    • Offer H, Erez N, Zurer I, Tang X, Milyavsky M, Goldfinger N and Rotter V (2002) The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA. Carcinogenesis 23: 1025-1032.
    • (2002) Carcinogenesis , vol.23 , pp. 1025-1032
    • Offer, H.1    Erez, N.2    Zurer, I.3    Tang, X.4    Milyavsky, M.5    Goldfinger, N.6    Rotter, V.7
  • 75
    • 0035865399 scopus 로고    scopus 로고
    • A role for p53 in base excision repair
    • Zhou J, Ahn J, Wilson SH and Prives C (2001) A role for p53 in base excision repair. EMBO J. 20: 914-923.
    • (2001) EMBO J. , vol.20 , pp. 914-923
    • Zhou, J.1    Ahn, J.2    Wilson, S.H.3    Prives, C.4
  • 77
    • 0033570048 scopus 로고    scopus 로고
    • Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo
    • Gaiddon C, Moorthy NC and Prives C (1999) Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo. EMBO J. 18: 5609-5621.
    • (1999) EMBO J. , vol.18 , pp. 5609-5621
    • Gaiddon, C.1    Moorthy, N.C.2    Prives, C.3
  • 78
    • 20544433877 scopus 로고    scopus 로고
    • Roles of thioredoxin reductase 1 and APE/Ref-1 in the control of basal p53 stability and activity
    • Seemann S and Hainaut P (2005) Roles of thioredoxin reductase 1 and APE/ Ref-1 in the control of basal p53 stability and activity. Oncogene 24: 3853-3863.
    • (2005) Oncogene , vol.24 , pp. 3853-3863
    • Seemann, S.1    Hainaut, P.2
  • 79
    • 85047698593 scopus 로고    scopus 로고
    • Implication of p53 in base excision DNA repair: In vivo evidence
    • Seo YR, Fishel ML, Amundson S, Kelley MR and Smith ML (2002) Implication of p53 in base excision DNA repair: In vivo evidence. Oncogene 21: 731-737.
    • (2002) Oncogene , vol.21 , pp. 731-737
    • Seo, Y.R.1    Fishel, M.L.2    Amundson, S.3    Kelley, M.R.4    Smith, M.L.5
  • 81
    • 4444323263 scopus 로고    scopus 로고
    • p53 functions in the incorporation step in DNA base excision repair in mouse liver mitochondria
    • de Souza-Pinto NC, Harris CC and Bohr VA (2004) p53 functions in the incorporation step in DNA base excision repair in mouse liver mitochondria. Oncogene 23: 6559-6568.
    • (2004) Oncogene , vol.23 , pp. 6559-6568
    • de Souza-Pinto, N.C.1    Harris, C.C.2    Bohr, V.A.3
  • 82
    • 0033584445 scopus 로고    scopus 로고
    • Drug-induced apoptosis is delayed and reduced in XPD lymphoblastoid cell lines: Possible role of TFIIH in p53-mediated apoptotic cell death
    • Robles AI, Wang XW and Harris CC (1999) Drug-induced apoptosis is delayed and reduced in XPD lymphoblastoid cell lines: Possible role of TFIIH in p53-mediated apoptotic cell death. Oncogene 18: 4681-4688.
    • (1999) Oncogene , vol.18 , pp. 4681-4688
    • Robles, A.I.1    Wang, X.W.2    Harris, C.C.3
  • 83
    • 4544259868 scopus 로고    scopus 로고
    • Transcription - Guarding the genome by sensing DNA damage
    • Ljungman M and Lane DP (2004) Transcription - guarding the genome by sensing DNA damage. Nat. Rev. Cancer 4: 727-737.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 727-737
    • Ljungman, M.1    Lane, D.P.2
  • 84
    • 0030899811 scopus 로고    scopus 로고
    • Complex formation between p53 and replication protein A inhibits the sequence-specific DNA binding of p53 and is regulated by single-stranded DNA
    • Miller SD, Moses K, Jayaraman L and Prives C (1997) Complex formation between p53 and replication protein A inhibits the sequence-specific DNA binding of p53 and is regulated by single-stranded DNA. Mol. Cell. Biol. 17: 2194-2201.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2194-2201
    • Miller, S.D.1    Moses, K.2    Jayaraman, L.3    Prives, C.4
  • 85
    • 0030872645 scopus 로고    scopus 로고
    • Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner
    • Abramova NA, Russell J, Botchan M and Li R (1997) Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner. Proc. Natl. Acad. Sci. USA 94: 7186-7191.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7186-7191
    • Abramova, N.A.1    Russell, J.2    Botchan, M.3    Li, R.4
  • 86
    • 0141757494 scopus 로고    scopus 로고
    • Regulation and mechanisms of mammalian double-strand break repair
    • Valerie K and Povirk LF (2003) Regulation and mechanisms of mammalian double-strand break repair. Oncogene 22: 5792-5812.
    • (2003) Oncogene , vol.22 , pp. 5792-5812
    • Valerie, K.1    Povirk, L.F.2
  • 87
    • 0942268167 scopus 로고    scopus 로고
    • Repair of DNA double strand breaks by non-homologous end joining
    • Lees-Miller SP and Meek K (2003) Repair of DNA double strand breaks by non-homologous end joining. Biochimie 85: 1161-1173.
    • (2003) Biochimie , vol.85 , pp. 1161-1173
    • Lees-Miller, S.P.1    Meek, K.2
  • 89
    • 0142011461 scopus 로고    scopus 로고
    • The cellular response to DNA double-strand breaks: Defining the sensors and mediators
    • Petrini JHJ and Strecker TH (2003) The cellular response to DNA double-strand breaks: Defining the sensors and mediators. Trends Cell Biol. 13: 458-462.
    • (2003) Trends Cell Biol. , vol.13 , pp. 458-462
    • Petrini, J.H.J.1    Strecker, T.H.2
  • 90
    • 6944226229 scopus 로고    scopus 로고
    • MRE11/RAD50/NBS1: Complex activities
    • Assenmacher N and Hopfner KP (2004) MRE11/RAD50/NBS1: Complex activities. Chromosome 113: 157-166.
    • (2004) Chromosome , vol.113 , pp. 157-166
    • Assenmacher, N.1    Hopfner, K.P.2
  • 91
    • 25144469291 scopus 로고    scopus 로고
    • The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM
    • Paull TT and Lee JH (2005) The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM. Cell Cycle 4: 737-740.
    • (2005) Cell Cycle , vol.4 , pp. 737-740
    • Paull, T.T.1    Lee, J.H.2
  • 93
    • 6344234817 scopus 로고    scopus 로고
    • Genetic steps of mammalian homologous repair with distinct mutagenic consequences
    • Stark JM, Pierce AJ, Oh J, Pastink A and Jasin M (2004) Genetic steps of mammalian homologous repair with distinct mutagenic consequences. Mol. Cell. Biol. 24: 9305-9316.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9305-9316
    • Stark, J.M.1    Pierce, A.J.2    Oh, J.3    Pastink, A.4    Jasin, M.5
  • 94
    • 0042632901 scopus 로고    scopus 로고
    • Pathways of DNA double-strand break repair during mammalian cell cycle
    • Rothkamm K, Krüger I, Thompson LT and Löbrich M (2003) Pathways of DNA double-strand break repair during mammalian cell cycle. Mol. Cell. Biol. 23: 5706-5715.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5706-5715
    • Rothkamm, K.1    Krüger, I.2    Thompson, L.T.3    Löbrich, M.4
  • 95
    • 0036127530 scopus 로고    scopus 로고
    • A role for p53 in the frequency and mechanism of mutation
    • Morris SM (2002) A role for p53 in the frequency and mechanism of mutation. Mutat. Res. 511: 45-62.
    • (2002) Mutat. Res. , vol.511 , pp. 45-62
    • Morris, S.M.1
  • 96
    • 0028144964 scopus 로고
    • Different capacities for recombination in closely related human lymphoblastoid cell lines with different mutational responses to X-irradiation
    • Xia F, Amundson SA, Nickoloff JA and Liber HL (1994) Different capacities for recombination in closely related human lymphoblastoid cell lines with different mutational responses to X-irradiation. Mol. Cell. Biol. 14: 5850-5857.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5850-5857
    • Xia, F.1    Amundson, S.A.2    Nickoloff, J.A.3    Liber, H.L.4
  • 99
    • 0141816840 scopus 로고    scopus 로고
    • Atm-, p53-, Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development
    • Bishop AJ, Hollander MC, Kosaras B, Sidman RL, Fornace Jr AJ and Schiestl RH (2003) Atm-, p53-, Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development. Cancer Res. 63: 5335-5343.
    • (2003) Cancer Res. , vol.63 , pp. 5335-5343
    • Bishop, A.J.1    Hollander, M.C.2    Kosaras, B.3    Sidman, R.L.4    Fornace Jr., A.J.5    Schiestl, R.H.6
  • 101
    • 0031452623 scopus 로고    scopus 로고
    • Normal meiotic recombination in p53-deficient mice
    • Gersten KM and Kemp CJ (1997) Normal meiotic recombination in p53-deficient mice. Nature Genet. 17: 378-379.
    • (1997) Nature Genet. , vol.17 , pp. 378-379
    • Gersten, K.M.1    Kemp, C.J.2
  • 102
    • 0030068266 scopus 로고    scopus 로고
    • In vivo assay of p53 function in homologous recombination between Simian Virus 40 chromosomes
    • Wiesmüller L, Cammenga J and Deppert W (1996) In vivo assay of p53 function in homologous recombination between Simian Virus 40 chromosomes. J. Virol. 70: 737-744.
    • (1996) J. Virol. , vol.70 , pp. 737-744
    • Wiesmüller, L.1    Cammenga, J.2    Deppert, W.3
  • 103
    • 2342596221 scopus 로고    scopus 로고
    • Recombinational DNA repair in cancer and normal cells: The challenge of functional analysis
    • Willers H, Xia F and Powell SN (2002) Recombinational DNA repair in cancer and normal cells: The challenge of functional analysis. J. Biomed. Biotechnol. 2: 86-93.
    • (2002) J. Biomed. Biotechnol. , vol.2 , pp. 86-93
    • Willers, H.1    Xia, F.2    Powell, S.N.3
  • 105
    • 0037416149 scopus 로고    scopus 로고
    • BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination
    • Sengupta S, Linke SP and Pedeux R (2003) BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. EMBO J. 22: 1210-1222.
    • (2003) EMBO J. , vol.22 , pp. 1210-1222
    • Sengupta, S.1    Linke, S.P.2    Pedeux, R.3
  • 106
    • 0030930925 scopus 로고    scopus 로고
    • Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein
    • Bertrand P, Rouillard D, Boulet A, Levalois C, Soussi T and Lopez BS (1997) Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein. Oncogene 14: 1117-1122.
    • (1997) Oncogene , vol.14 , pp. 1117-1122
    • Bertrand, P.1    Rouillard, D.2    Boulet, A.3    Levalois, C.4    Soussi, T.5    Lopez, B.S.6
  • 108
    • 0033578066 scopus 로고    scopus 로고
    • Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint
    • Saintigny Y, Rouillard D, Chaput B, Soussi T and Lopez BS (1999) Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint. Oncogene 18: 3553-3565.
    • (1999) Oncogene , vol.18 , pp. 3553-3565
    • Saintigny, Y.1    Rouillard, D.2    Chaput, B.3    Soussi, T.4    Lopez, B.S.5
  • 109
    • 0034598771 scopus 로고    scopus 로고
    • Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control
    • Willers H, McCarthy EE, Wu B, Wunsch H, Tang W, Taghian DG, Xia F and Powell SN (2000) Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control. Oncogene 19: 632-639.
    • (2000) Oncogene , vol.19 , pp. 632-639
    • Willers, H.1    McCarthy, E.E.2    Wu, B.3    Wunsch, H.4    Tang, W.5    Taghian, D.G.6    Xia, F.7    Powell, S.N.8
  • 110
    • 0037663419 scopus 로고    scopus 로고
    • p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair
    • Boehden GS, Akyüz N, Roemer K and Wiesmüller L (2003) p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair. Oncogene 22: 4111-4117.
    • (2003) Oncogene , vol.22 , pp. 4111-4117
    • Boehden, G.S.1    Akyüz, N.2    Roemer, K.3    Wiesmüller, L.4
  • 111
    • 0035164722 scopus 로고    scopus 로고
    • Homologous recombination in extrachromosomal plasmid substrates is not suppressed by p53
    • Willers H, McCarthy EE, Hubb P, Dahm-Daphi J and Powell SN (2001) Homologous recombination in extrachromosomal plasmid substrates is not suppressed by p53. Carcinogenesis 22: 1757-1763.
    • (2001) Carcinogenesis , vol.22 , pp. 1757-1763
    • Willers, H.1    McCarthy, E.E.2    Hubb, P.3    Dahm-Daphi, J.4    Powell, S.N.5
  • 113
    • 0035898405 scopus 로고    scopus 로고
    • Characterization of homologous recombination induced by replication inhibition in mammalian cells
    • Saintigny Y, Delacote YF, Vares G, Petitot F, Lambert S, Averbeck D and Lopez BS (2001) Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO J. 20: 3861-3870.
    • (2001) EMBO J. , vol.20 , pp. 3861-3870
    • Saintigny, Y.1    Delacote, Y.F.2    Vares, G.3    Petitot, F.4    Lambert, S.5    Averbeck, D.6    Lopez, B.S.7
  • 114
    • 0033954246 scopus 로고    scopus 로고
    • Replication fork pausing and recombination or 'gimme a break'
    • Rothstein R, Michel B and Gangloff S (2000) Replication fork pausing and recombination or 'gimme a break'. Genes Dev. 14: 1-10.
    • (2000) Genes Dev. , vol.14 , pp. 1-10
    • Rothstein, R.1    Michel, B.2    Gangloff, S.3
  • 115
    • 0037122919 scopus 로고    scopus 로고
    • Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53
    • Saintigny Y and Lopez BS (2002) Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53. Oncogene 21: 488-492.
    • (2002) Oncogene , vol.21 , pp. 488-492
    • Saintigny, Y.1    Lopez, B.S.2
  • 116
    • 0037194615 scopus 로고    scopus 로고
    • Wildtype p53 inhibits replication-associated homologous recombination
    • Janz C and Wiesmüller L (2002) Wildtype p53 inhibits replication-associated homologous recombination. Oncogene 21: 5229-5933.
    • (2002) Oncogene , vol.21 , pp. 5229-5933
    • Janz, C.1    Wiesmüller, L.2
  • 117
    • 0031893222 scopus 로고    scopus 로고
    • Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage
    • Paulson TG, Almasan A, Brody LL and Wahl GM (1998) Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage. Mol. Cell. Biol. 18: 3089-3100.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3089-3100
    • Paulson, T.G.1    Almasan, A.2    Brody, L.L.3    Wahl, G.M.4
  • 118
    • 1842432466 scopus 로고    scopus 로고
    • p53 protects from replication-associated DNA double-strand breaks in mammalian cells
    • Kumari A, Schultz N and Helleday T (2004) p53 protects from replication-associated DNA double-strand breaks in mammalian cells. Oncogene 23: 2324-2329.
    • (2004) Oncogene , vol.23 , pp. 2324-2329
    • Kumari, A.1    Schultz, N.2    Helleday, T.3
  • 119
    • 17144379297 scopus 로고    scopus 로고
    • p53 prevents the accumulation of double-strand DNA breaks at stalled-replication forks induced by UV in human cells
    • Squires S, Coates JA, Goldberg M, Toji LH, Jackson SP, Clarke DJ and Johnson RT (2004) p53 prevents the accumulation of double-strand DNA breaks at stalled-replication forks induced by UV in human cells. Cell Cycle 3: 1543-1557.
    • (2004) Cell Cycle , vol.3 , pp. 1543-1557
    • Squires, S.1    Coates, J.A.2    Goldberg, M.3    Toji, L.H.4    Jackson, S.P.5    Clarke, D.J.6    Johnson, R.T.7
  • 120
    • 0037130465 scopus 로고    scopus 로고
    • Association of p53 and MSH2 with recombinative repair complexes during S phase
    • Zink D, Mayr C, Janz C and Wiesmüller L (2002) Association of p53 and MSH2 with recombinative repair complexes during S phase. Oncogene 21: 4788-4800.
    • (2002) Oncogene , vol.21 , pp. 4788-4800
    • Zink, D.1    Mayr, C.2    Janz, C.3    Wiesmüller, L.4
  • 121
    • 21744432851 scopus 로고    scopus 로고
    • Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination
    • Restle A, Janz C and Wiesmuller L (2005) Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination. Oncogene 24: 4367-4380.
    • (2005) Oncogene , vol.24 , pp. 4367-4380
    • Restle, A.1    Janz, C.2    Wiesmuller, L.3
  • 122
    • 85047680162 scopus 로고    scopus 로고
    • p53 accumulates but is functionally impaired when DNA synthesis is blocked
    • Gottifredi V, Shieh S, Taya Y and Prives C (2001) p53 accumulates but is functionally impaired when DNA synthesis is blocked. Proc. Natl. Acad. Sci. USA 98: 1036-1041.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1036-1041
    • Gottifredi, V.1    Shieh, S.2    Taya, Y.3    Prives, C.4
  • 123
    • 0029969418 scopus 로고    scopus 로고
    • p53 is linked directly to homologous recombination processes via Rad51/RecA protein interaction
    • Stürzbecher HW, Donzelmann B, Henning W, Knippschild U and Buchhop S (1996) p53 is linked directly to homologous recombination processes via Rad51/RecA protein interaction. EMBO J. 15: 1992-2002.
    • (1996) EMBO J. , vol.15 , pp. 1992-2002
    • Stürzbecher, H.W.1    Donzelmann, B.2    Henning, W.3    Knippschild, U.4    Buchhop, S.5
  • 125
    • 0034648693 scopus 로고    scopus 로고
    • Role of heteroduplex joints in the functional interactions between human Rad51 and wildtype p53
    • Süsse S, Janz C, Janus F, Deppert W and Wiesmüller L (2000) Role of heteroduplex joints in the functional interactions between human Rad51 and wildtype p53. Oncogene 19: 4500-4512.
    • (2000) Oncogene , vol.19 , pp. 4500-4512
    • Süsse, S.1    Janz, C.2    Janus, F.3    Deppert, W.4    Wiesmüller, L.5
  • 127
    • 0032506021 scopus 로고    scopus 로고
    • The BRCA2 gene product functionally interacts with p53 and Rad51
    • Marmorstein LY, Ouchi T and Aaronson SA (1998) The BRCA2 gene product functionally interacts with p53 and Rad51. Proc. Natl. Acad. Sci. USA 95: 13869-13874.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13869-13874
    • Marmorstein, L.Y.1    Ouchi, T.2    Aaronson, S.A.3
  • 128
    • 0037115914 scopus 로고    scopus 로고
    • Homologous repair of DNA damage and tumourigenesis: The BRCA connection
    • Jasin M (2002) Homologous repair of DNA damage and tumourigenesis: The BRCA connection. Oncogene 21: 8981-8993.
    • (2002) Oncogene , vol.21 , pp. 8981-8993
    • Jasin, M.1
  • 129
    • 10944230682 scopus 로고    scopus 로고
    • The interaction of p53 with replication protein A mediates suppression of homologous recombination
    • Romanova LY, Willers H, Blagosklonny MV and Powell SN (2004) The interaction of p53 with replication protein A mediates suppression of homologous recombination. Oncogene 23: 9025-9033.
    • (2004) Oncogene , vol.23 , pp. 9025-9033
    • Romanova, L.Y.1    Willers, H.2    Blagosklonny, M.V.3    Powell, S.N.4
  • 133
    • 0842332845 scopus 로고    scopus 로고
    • p53 inhibits strand exchange and replication fork regression promoted by human Rad51
    • Yoon D, Wang Y, Stapleford K, Wiesmüller L and Chen J (2004) p53 inhibits strand exchange and replication fork regression promoted by human Rad51. J. Mol. Biol. 336: 639-654.
    • (2004) J. Mol. Biol. , vol.336 , pp. 639-654
    • Yoon, D.1    Wang, Y.2    Stapleford, K.3    Wiesmüller, L.4    Chen, J.5
  • 134
    • 13544267789 scopus 로고    scopus 로고
    • Discriminatory suppression of homologous recombination by p53
    • Yun S, Lie-A-Cheong C and Porter AC (2004) Discriminatory suppression of homologous recombination by p53. Nucleic Acids Res. 32: 6479-6489.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 6479-6489
    • Yun, S.1    Lie-A-Cheong, C.2    Porter, A.C.3
  • 135
    • 0036308710 scopus 로고    scopus 로고
    • p53 blocks RuvAB promoted branch migration and modulates resolution of Holliday junctions by RuvC
    • Prabhu VP, Simons AM, Iwasaki H, Gai D, Simmons DT and Chen J (2002) p53 blocks RuvAB promoted branch migration and modulates resolution of Holliday junctions by RuvC. J. Mol. Biol. 316: 1023-1032.
    • (2002) J. Mol. Biol. , vol.316 , pp. 1023-1032
    • Prabhu, V.P.1    Simons, A.M.2    Iwasaki, H.3    Gai, D.4    Simmons, D.T.5    Chen, J.6
  • 136
    • 0035937782 scopus 로고    scopus 로고
    • Analysis of the binding of p53 to DNAs containing mismatched and bulged bases
    • Degtyareva N, Subramanian D and Griffith JD (2001) Analysis of the binding of p53 to DNAs containing mismatched and bulged bases. J. Biol. Chem. 276: 8778-8784.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8778-8784
    • Degtyareva, N.1    Subramanian, D.2    Griffith, J.D.3
  • 137
    • 0031051010 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA
    • Alani E, Lee S, Kane MF, Griffith J and Kolodner RD (1997) Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA. J. Mol. Biol. 265: 289-301.
    • (1997) J. Mol. Biol. , vol.265 , pp. 289-301
    • Alani, E.1    Lee, S.2    Kane, M.F.3    Griffith, J.4    Kolodner, R.D.5
  • 138
    • 0035081417 scopus 로고    scopus 로고
    • Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells
    • Elliott B and Jasin M (2001) Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells. Mol. Cell. Biol. 21: 2671-2682.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 2671-2682
    • Elliott, B.1    Jasin, M.2
  • 140
    • 0036606419 scopus 로고    scopus 로고
    • Interactions between p53, hMSH2-hMSH6 and HMG I(Y) on Holliday junctions and bulged bases
    • Subramanian D and Griffith JD (2002) Interactions between p53, hMSH2-hMSH6 and HMG I(Y) on Holliday junctions and bulged bases. Nucleic Acids Res. 30: 2427-2434.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 2427-2434
    • Subramanian, D.1    Griffith, J.D.2
  • 141
    • 14044253551 scopus 로고    scopus 로고
    • Modulation of p53 binding to Holliday junctions and 3-cytosine bulges by phosphorylation events
    • Subramanian D and Griffith JD (2005) Modulation of p53 binding to Holliday junctions and 3-cytosine bulges by phosphorylation events. Biochemistry 44: 2536-2544.
    • (2005) Biochemistry , vol.44 , pp. 2536-2544
    • Subramanian, D.1    Griffith, J.D.2
  • 143
    • 0141567744 scopus 로고    scopus 로고
    • RecQ helicases: Suppressors of tumourigenesis and premature aging
    • Bachrati CZ and Hickson ID (2003) RecQ helicases: Suppressors of tumourigenesis and premature aging. Biochem. J. 374: 577-606.
    • (2003) Biochem. J. , vol.374 , pp. 577-606
    • Bachrati, C.Z.1    Hickson, I.D.2
  • 145
    • 17144395509 scopus 로고    scopus 로고
    • ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation
    • Davalos AR, Kaminker P, Hansen RK and Campisi J (2004) ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation. Cell Cycle 3: 1579-1586.
    • (2004) Cell Cycle , vol.3 , pp. 1579-1586
    • Davalos, A.R.1    Kaminker, P.2    Hansen, R.K.3    Campisi, J.4
  • 147
    • 0033153336 scopus 로고    scopus 로고
    • p53 directly enhances rejoining of DNA double-strand breaks with cohesive ends in gamma-irradiated mouse fibroblasts
    • Tang W, Willers H and Powell SN (1999) p53 directly enhances rejoining of DNA double-strand breaks with cohesive ends in gamma-irradiated mouse fibroblasts. Cancer Res. 59: 2562-2565.
    • (1999) Cancer Res. , vol.59 , pp. 2562-2565
    • Tang, W.1    Willers, H.2    Powell, S.N.3
  • 149
    • 0032807840 scopus 로고    scopus 로고
    • The tumor suppressor p53 can reduce stable transfection in the presence of irradiation
    • Lee H, Sun D, Larner JM and Wu FS (1999) The tumor suppressor p53 can reduce stable transfection in the presence of irradiation. J. Biomed. Sci. 6: 285-292.
    • (1999) J. Biomed. Sci. , vol.6 , pp. 285-292
    • Lee, H.1    Sun, D.2    Larner, J.M.3    Wu, F.S.4
  • 150
    • 0036253156 scopus 로고    scopus 로고
    • Effect of wildtype, S15D and R175H p53 proteins on DNA end-joining in vitro: Potential mechanism of DNA double-strand break repair modulation
    • Okorokov AL, Warnock L and Milner J (2002) Effect of wildtype, S15D and R175H p53 proteins on DNA end-joining in vitro: Potential mechanism of DNA double-strand break repair modulation. Carcinogenesis 23: 549-557.
    • (2002) Carcinogenesis , vol.23 , pp. 549-557
    • Okorokov, A.L.1    Warnock, L.2    Milner, J.3
  • 151
    • 14944342130 scopus 로고    scopus 로고
    • Nonhomologous end-joining of site-specific but not of radiation-induced DNA double-strand breaks is reduced in the presence of wildtype p53
    • Dahm-Daphi J, Hubbe P, Horvath F, El-Awady RA, Bouffard KE, Powell SN and Willers H (2005) Nonhomologous end-joining of site-specific but not of radiation-induced DNA double-strand breaks is reduced in the presence of wildtype p53. Oncogene 24: 1663-1672.
    • (2005) Oncogene , vol.24 , pp. 1663-1672
    • Dahm-Daphi, J.1    Hubbe, P.2    Horvath, F.3    El-Awady, R.A.4    Bouffard, K.E.5    Powell, S.N.6    Willers, H.7
  • 152
    • 0032499298 scopus 로고    scopus 로고
    • Radioresistant MTp53-expressing rat embryo transformants exhibit increased DNA dsb rejoining during exposure to ionising radiation
    • Bristow RG, Hu Q, Jang A, Chung S, Peacock J, Benchimol S and Hill R (1998) Radioresistant MTp53-expressing rat embryo transformants exhibit increased DNA dsb rejoining during exposure to ionising radiation. Oncogene 16: 1789-1802.
    • (1998) Oncogene , vol.16 , pp. 1789-1802
    • Bristow, R.G.1    Hu, Q.2    Jang, A.3    Chung, S.4    Peacock, J.5    Benchimol, S.6    Hill, R.7
  • 153
    • 0037413371 scopus 로고    scopus 로고
    • Suppression of high-fidelity double-strand break repair in mammalian chromosomes by pifithrin-alpha, a chemical inhibitor of p53
    • Lin Y, Waldman BC and Waldman AS (2003) Suppression of high-fidelity double-strand break repair in mammalian chromosomes by pifithrin-alpha, a chemical inhibitor of p53. DNA Repair 2: 1-11.
    • (2003) DNA Repair , vol.2 , pp. 1-11
    • Lin, Y.1    Waldman, B.C.2    Waldman, A.S.3
  • 154
    • 0034667882 scopus 로고    scopus 로고
    • p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core
    • Zotchev SB, Protopopova M and Selivanova G (2000) p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core. Nucleic Acids Res. 28: 4005-4012.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 4005-4012
    • Zotchev, S.B.1    Protopopova, M.2    Selivanova, G.3
  • 156
    • 85047695296 scopus 로고    scopus 로고
    • Increased error-prone non homologous DNA end-joining - A proposed mechanism of chromosomal instability in Bloom's syndrome
    • Gaymes TJ, North PS, Brady N, Hickson ID, Mufti GJ and Rassool FV (2002) Increased error-prone non homologous DNA end-joining - a proposed mechanism of chromosomal instability in Bloom's syndrome. Oncogene 21: 2525-2533.
    • (2002) Oncogene , vol.21 , pp. 2525-2533
    • Gaymes, T.J.1    North, P.S.2    Brady, N.3    Hickson, I.D.4    Mufti, G.J.5    Rassool, F.V.6
  • 157
    • 4344572619 scopus 로고    scopus 로고
    • Recombination at chromosomal sequences involved in leukaemogenic rearrangements is differentially regulated by p53
    • Boehden GS, Restle A, Marschalek R, Stocking C and Wiesmüller L (2004) Recombination at chromosomal sequences involved in leukaemogenic rearrangements is differentially regulated by p53. Carcinogenesis 25: 1-9.
    • (2004) Carcinogenesis , vol.25 , pp. 1-9
    • Boehden, G.S.1    Restle, A.2    Marschalek, R.3    Stocking, C.4    Wiesmüller, L.5
  • 158
    • 0032523932 scopus 로고    scopus 로고
    • Wildtype and mutant forms of p53 activate human topoisomerase I: A possible mechanism for gain of function in mutants
    • Albor A, Kaku S and Kulesz-Martin M (1998) Wildtype and mutant forms of p53 activate human topoisomerase I: A possible mechanism for gain of function in mutants. Cancer Res. 5: 2091-2094.
    • (1998) Cancer Res. , vol.5 , pp. 2091-2094
    • Albor, A.1    Kaku, S.2    Kulesz-Martin, M.3
  • 159
    • 0033621189 scopus 로고    scopus 로고
    • The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wildtype and mutant p53
    • Gobert C, Skladanowski A and Larsen AK (1999) The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wildtype and mutant p53. Proc. Natl. Acad. Sci. USA 96: 10355-10360.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10355-10360
    • Gobert, C.1    Skladanowski, A.2    Larsen, A.K.3
  • 160
    • 0037179899 scopus 로고    scopus 로고
    • The tumor suppressor protein p53 stimulates the formation of the human topoisomerase I double cleavage complex in vitro
    • Soe K, Hartmann H, Schlott B, Stevnsner T and Grosse F (2002) The tumor suppressor protein p53 stimulates the formation of the human topoisomerase I double cleavage complex in vitro. Oncogene 21: 6614-6623.
    • (2002) Oncogene , vol.21 , pp. 6614-6623
    • Soe, K.1    Hartmann, H.2    Schlott, B.3    Stevnsner, T.4    Grosse, F.5
  • 161
    • 0033396923 scopus 로고    scopus 로고
    • Involvement of p53 in X-ray induced intrachromosomal recombination in mice
    • Aubrecht J, Secretan MB, Bishop AJ and Schiestl RH (1999) Involvement of p53 in X-ray induced intrachromosomal recombination in mice. Carcinogenesis 20: 2229-2236.
    • (1999) Carcinogenesis , vol.20 , pp. 2229-2236
    • Aubrecht, J.1    Secretan, M.B.2    Bishop, A.J.3    Schiestl, R.H.4
  • 162
    • 20544466098 scopus 로고    scopus 로고
    • Wildtype p53 stimulates homologous recombination upon sequence-specific binding to ribosomal gene cluster repeat
    • Boehden GS, Baumann C, Siehler S and Wiesmüller L (2005) Wildtype p53 stimulates homologous recombination upon sequence-specific binding to ribosomal gene cluster repeat. Oncogene 24: 4183-4192.
    • (2005) Oncogene , vol.24 , pp. 4183-4192
    • Boehden, G.S.1    Baumann, C.2    Siehler, S.3    Wiesmüller, L.4
  • 166
    • 0028978183 scopus 로고
    • Mice lacking p21 cip1/waf1 undergo normal development, but are defective in G1 checkpoint control
    • Deng C, Zhang P, Harper JW, Elledge SJ and Leder P (1995) Mice lacking p21 cip1/waf1 undergo normal development, but are defective in G1 checkpoint control. Cell 82: 675-684.
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 170
    • 0027246307 scopus 로고
    • Germline mutations of the p53 tumor-suppressor gene in cancer-prone families: A review
    • Soussi T, Leblanc T, Baruchel A and Schaison G (1993) Germline mutations of the p53 tumor-suppressor gene in cancer-prone families: A review. Nouv. Rev. Fr. Hematol. 35: 33-36.
    • (1993) Nouv. Rev. Fr. Hematol. , vol.35 , pp. 33-36
    • Soussi, T.1    Leblanc, T.2    Baruchel, A.3    Schaison, G.4
  • 171
    • 0037202608 scopus 로고    scopus 로고
    • Recombinational DNA repair and human disease
    • Thompson LH and Schild D (2002) Recombinational DNA repair and human disease. Mutat. Res. 509: 49-78.
    • (2002) Mutat. Res. , vol.509 , pp. 49-78
    • Thompson, L.H.1    Schild, D.2
  • 172
    • 0034025077 scopus 로고    scopus 로고
    • Homologous and nonhomologous recombination resulting in deletion: Effects of p53 status, microhomology and repetitive DNA length and orientation
    • Gebow D, Miselis N and Liber HL (2000) Homologous and nonhomologous recombination resulting in deletion: Effects of p53 status, microhomology and repetitive DNA length and orientation. Mol. Cell. Biol. 20: 4028-4035.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4028-4035
    • Gebow, D.1    Miselis, N.2    Liber, H.L.3
  • 173
    • 0037469359 scopus 로고    scopus 로고
    • Activities of wildtype and mutant p53 in suppression of homologous recombination as measured by a retroviral vector system
    • Lu X, Lozano G and Donehower LA (2003) Activities of wildtype and mutant p53 in suppression of homologous recombination as measured by a retroviral vector system. Mutat. Res. 522: 69-83.
    • (2003) Mutat. Res. , vol.522 , pp. 69-83
    • Lu, X.1    Lozano, G.2    Donehower, L.A.3
  • 174
    • 3242883729 scopus 로고    scopus 로고
    • The p53 response to DNA damage
    • Meek DW (2004) The p53 response to DNA damage. DNA Repair 3: 1049-1056.
    • (2004) DNA Repair , vol.3 , pp. 1049-1056
    • Meek, D.W.1


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