p53 prevents the accumulation of double-strand DNA breaks at stalled-replication forks induced by UV in human cells

Cell Cycle

Volumn 3, Issue 12, 2004, Pages 1543-1557

  Squires, Shoshana ^a   Coates, Julia A ^a,b   Goldberg, Michal ^a,b,c   Toji, Lorraine H ^d   Jackson, Stephen P ^a,b   Clarke, Duncan J ^a,e   Johnson, Robert T ^a,f  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^d Laboratory of Molecular and Cellular Biology of Hematopoiesis   (United States)

^e UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^f MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

Author keywords

Double strand breaks; Genome stability; p53; Stalled replication forks; UV damage; XP; XPV

Indexed keywords

DOUBLE STRANDED DNA; PROTEIN P53;

ARTICLE; CELL CYCLE S PHASE; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DETERMINATION; DNA REPLICATION; DNA STRAND BREAKAGE; DNA STRUCTURE; DNA SYNTHESIS INHIBITION; EXCISION REPAIR; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; PULSED FIELD GEL ELECTROPHORESIS; ULTRAVIOLET IRRADIATION; XERODERMA PIGMENTOSUM;

MAMMALIA;

EID: 17144379297     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.3.12.1272     Document Type: Article

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