-
1
-
-
0028969514
-
Genetic instability as a consequence of inappropriate entry into and progression through S-phase
-
Almasan, A., S. P. Linke, T. G. Paulson, L. Huang, and G. M. Wahl. 1995. Genetic instability as a consequence of inappropriate entry into and progression through S-phase. Cancer Metas. Rev. 14:59-73.
-
(1995)
Cancer Metas. Rev.
, vol.14
, pp. 59-73
-
-
Almasan, A.1
Linke, S.P.2
Paulson, T.G.3
Huang, L.4
Wahl, G.M.5
-
2
-
-
0029050533
-
pRb deficiency leads to inappropriate entry into S-phase, activation of E2F responsive genes and apoptosis
-
Almasan, A., Y. Yin, R. Kelly, E. Lee, A. Bradley, W. Li, J. Bertino, and G. Wahl. 1995. pRb deficiency leads to inappropriate entry into S-phase, activation of E2F responsive genes and apoptosis. Proc. Natl. Acad. Sci. USA 92:5436-5440.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5436-5440
-
-
Almasan, A.1
Yin, Y.2
Kelly, R.3
Lee, E.4
Bradley, A.5
Li, W.6
Bertino, J.7
Wahl, G.8
-
3
-
-
0028295872
-
Chromosome 13 transfer provides evidence for regulation of RB1 protein expression
-
Anderson, M. J., C. L. Fasching, H. J. Xu, W. F. Benedict, and E. J. Stanbridge. 1994. Chromosome 13 transfer provides evidence for regulation of RB1 protein expression. Genes Chromosomes Cancer 9:251-260.
-
(1994)
Genes Chromosomes Cancer
, vol.9
, pp. 251-260
-
-
Anderson, M.J.1
Fasching, C.L.2
Xu, H.J.3
Benedict, W.F.4
Stanbridge, E.J.5
-
4
-
-
0025319930
-
Molecular and genetic characterization of human cell lines resistant to L-asparaginase and albizziin
-
Andrulis, I. L., R. Argonza, and A. E. Cairney. 1990. Molecular and genetic characterization of human cell lines resistant to L-asparaginase and albizziin. Somat. Cell Mol. Genet. 16:59-65.
-
(1990)
Somat. Cell Mol. Genet.
, vol.16
, pp. 59-65
-
-
Andrulis, I.L.1
Argonza, R.2
Cairney, A.E.3
-
5
-
-
0003291213
-
One-dimensional gel electrophoresis of proteins
-
10.2. K. Jannsen (ed.), Wiley-Interscience, New York, N.Y.
-
Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith and K. Struhl. 1994. One-dimensional gel electrophoresis of proteins, 10.2. In K. Jannsen (ed.), Current protocols in molecular biology. Wiley-Interscience, New York, N.Y.
-
(1994)
Current Protocols in Molecular Biology
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
6
-
-
0021112720
-
Accumulation of DNA strand breaks during thymineless death in thymidylate synthase-negative mutants of mouse FM3A cells
-
Ayusawa, D., K. Shimizu, H. Koyama, K. Takeishi, and T. Seno. 1983. Accumulation of DNA strand breaks during thymineless death in thymidylate synthase-negative mutants of mouse FM3A cells. J. Biol. Chem. 258: 12448-12454.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 12448-12454
-
-
Ayusawa, D.1
Shimizu, K.2
Koyama, H.3
Takeishi, K.4
Seno, T.5
-
7
-
-
0026102788
-
Double minute chromosomes and homogeneously staining regions in tumors taken directly from patients versus in human tumor cell lines
-
Benner, S. E., G. M. Wahl, and H. D. Von. 1991. Double minute chromosomes and homogeneously staining regions in tumors taken directly from patients versus in human tumor cell lines. Anticancer Drugs 2:11-25.
-
(1991)
Anticancer Drugs
, vol.2
, pp. 11-25
-
-
Benner, S.E.1
Wahl, G.M.2
Von, H.D.3
-
9
-
-
0020604325
-
Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea
-
Brown, P. C., T. D. Tlsty, and R. T. Schimke. 1983. Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea. Mol. Cell. Biol. 3:1097-1107.
-
(1983)
Mol. Cell. Biol.
, vol.3
, pp. 1097-1107
-
-
Brown, P.C.1
Tlsty, T.D.2
Schimke, R.T.3
-
10
-
-
0029741951
-
Separate pathways for p53 induction by ionizing radiation and N-(Phosphonoacetyl)-L aspartate
-
Chen, C., I. Hall, T. Lansing, T. Gilmer, and M. Kastan. 1996. Separate pathways for p53 induction by ionizing radiation and N-(Phosphonoacetyl)-L aspartate. Cancer Res. 56:3659-3662.
-
(1996)
Cancer Res.
, vol.56
, pp. 3659-3662
-
-
Chen, C.1
Hall, I.2
Lansing, T.3
Gilmer, T.4
Kastan, M.5
-
11
-
-
0017346890
-
In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain
-
Chen, T. R. 1977. In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain. Exp. Cell Res. 104:255-262.
-
(1977)
Exp. Cell Res.
, vol.104
, pp. 255-262
-
-
Chen, T.R.1
-
12
-
-
0027532443
-
An analysis of vincristine-resistance in BHK cells pretreated with 1-beta-D-arabinofuranosylcytosine
-
Chen, Y., B. Goz, and L. Kirkman. 1993. An analysis of vincristine-resistance in BHK cells pretreated with 1-beta-D-arabinofuranosylcytosine. Anticancer Res. 13:249-255.
-
(1993)
Anticancer Res.
, vol.13
, pp. 249-255
-
-
Chen, Y.1
Goz, B.2
Kirkman, L.3
-
13
-
-
0030904279
-
Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons
-
Coquelle, A., E. Pipiras, F. Toledo, G. Buttin, and M. Debatisse. 1997. Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons. Cell 89:215-225.
-
(1997)
Cell
, vol.89
, pp. 215-225
-
-
Coquelle, A.1
Pipiras, E.2
Toledo, F.3
Buttin, G.4
Debatisse, M.5
-
14
-
-
0020965275
-
Occurrence and evolution of homogeneously staining regions may be due to breakage-fusion-bridge cycles following telomere loss
-
Cowell, J. K., and O. J. Miller. 1983. Occurrence and evolution of homogeneously staining regions may be due to breakage-fusion-bridge cycles following telomere loss. Chromosoma 88:216-221.
-
(1983)
Chromosoma
, vol.88
, pp. 216-221
-
-
Cowell, J.K.1
Miller, O.J.2
-
15
-
-
0028913739
-
A p53-dependent mouse spindle checkpoint
-
Cross, S. M., C. A. Sanchez, C. A. Morgan, M. K. Schimke, S. Ramel, R. L. Idzerda, W. H. Raskind, and B. J. Reid. 1995. A p53-dependent mouse spindle checkpoint. Science 267:1353-6.
-
(1995)
Science
, vol.267
, pp. 1353-1356
-
-
Cross, S.M.1
Sanchez, C.A.2
Morgan, C.A.3
Schimke, M.K.4
Ramel, S.5
Idzerda, R.L.6
Raskind, W.H.7
Reid, B.J.8
-
17
-
-
0029616222
-
Mitotic and post mitotic consequences of genomic instability induced by oncogenic Ha-ras
-
Denko, N., J. Stringer, M. Wani, and P. Stambrook. 1995. Mitotic and post mitotic consequences of genomic instability induced by oncogenic Ha-ras. Somat. Cell Mol. Genet. 21:241-253.
-
(1995)
Somat. Cell Mol. Genet.
, vol.21
, pp. 241-253
-
-
Denko, N.1
Stringer, J.2
Wani, M.3
Stambrook, P.4
-
18
-
-
0028338927
-
The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle
-
Denko, N. C., A. J. Giaccia, J. R. Stringer, and P. J. Stambrook. 1994. The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle. Proc. Natl. Acad. Sci. USA 91:5124-5128.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5124-5128
-
-
Denko, N.C.1
Giaccia, A.J.2
Stringer, J.R.3
Stambrook, P.J.4
-
19
-
-
0027155140
-
Transfected c-Ha-ras oncogene enhances karyotypic instability and integrates predominantly in aberrant chromosomes
-
de Vries, J. E., F. H. Kornips, P. Marx, F. T. Bosman, J. P. Geraedts, and J. ten Kate. 1993. Transfected c-Ha-ras oncogene enhances karyotypic instability and integrates predominantly in aberrant chromosomes. Cancer Genet. Cytogenet. 67:35-43.
-
(1993)
Cancer Genet. Cytogenet.
, vol.67
, pp. 35-43
-
-
De Vries, J.E.1
Kornips, F.H.2
Marx, P.3
Bosman, F.T.4
Geraedts, J.P.5
Ten Kate, J.6
-
20
-
-
0027536498
-
DNA topoisomerase II inhibition and gene amplification in V79/B7 cells
-
Di Leonardo, A., P. Cavolina, and A. Maddalena. 1993. DNA topoisomerase II inhibition and gene amplification in V79/B7 cells. Mutat. Res. 301:177-182.
-
(1993)
Mutat. Res.
, vol.301
, pp. 177-182
-
-
Di Leonardo, A.1
Cavolina, P.2
Maddalena, A.3
-
21
-
-
0030929838
-
DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function
-
Di Leonardo, A., S. H. Khan, S. P. Linke, V. Greco, G. Seidita, and G. M. Wahl. 1997. DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function. Cancer Res. 57:1013-1019.
-
(1997)
Cancer Res.
, vol.57
, pp. 1013-1019
-
-
Di Leonardo, A.1
Khan, S.H.2
Linke, S.P.3
Greco, V.4
Seidita, G.5
Wahl, G.M.6
-
22
-
-
0027970713
-
DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
-
Di Leonardo, A., S. P. Linke, K. Clarkin, and G. M. Wahl. 1994. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes Dev. 8:2540-2551.
-
(1994)
Genes Dev.
, vol.8
, pp. 2540-2551
-
-
Di Leonardo, A.1
Linke, S.P.2
Clarkin, K.3
Wahl, G.M.4
-
23
-
-
0027822553
-
Cell cycle regulation of gene amplification
-
Di Leonardo, A., S. P. Linke, Y. Yin, and G. M. Wahl. 1993. Cell cycle regulation of gene amplification. Cold Spring Harbor Symp. Quant. Biol. 58:655-667.
-
(1993)
Cold Spring Harbor Symp. Quant. Biol.
, vol.58
, pp. 655-667
-
-
Di Leonardo, A.1
Linke, S.P.2
Yin, Y.3
Wahl, G.M.4
-
24
-
-
0016958680
-
Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells
-
Flintoff, W. F., S. V. Davidson, and L. Siminovitch. 1976. Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells. Somat. Cell Genet. 2:245-261.
-
(1976)
Somat. Cell Genet.
, vol.2
, pp. 245-261
-
-
Flintoff, W.F.1
Davidson, S.V.2
Siminovitch, L.3
-
25
-
-
0344100948
-
Development of methotrexate resistance in a human squamous cell carcinoma of the head and neck in culture
-
Frei, E., A. Rosowsky, J. E. Wright, C. A. Cucchi, J. A. Lippke, T. J. Ervin, J. Jolivet, and W. A. Haseltine. 1984. Development of methotrexate resistance in a human squamous cell carcinoma of the head and neck in culture. Proc. Natl. Acad. Sci. USA 81:2873-2877.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 2873-2877
-
-
Frei, E.1
Rosowsky, A.2
Wright, J.E.3
Cucchi, C.A.4
Lippke, J.A.5
Ervin, T.J.6
Jolivet, J.7
Haseltine, W.A.8
-
26
-
-
0031035639
-
Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability
-
Fukasawa, K., and G. F. Vande Woude. 1997. Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability. Mol. Cell. Biol. 17:506-518.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 506-518
-
-
Fukasawa, K.1
Vande Woude, G.F.2
-
27
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt, M. S., W. P. Bennett, M. Hollstein, and C. C. Harris. 1994. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 54:4855-4878.
-
(1994)
Cancer Res.
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
28
-
-
0027631352
-
Molecular biology of double-minute chromosomes
-
Hahn, P. J. 1993. Molecular biology of double-minute chromosomes. Bioessays 15:477-484.
-
(1993)
Bioessays
, vol.15
, pp. 477-484
-
-
Hahn, P.J.1
-
29
-
-
0028568315
-
Cell cycle control and cancer
-
Hartwell, L. H., and M. B. Kastan. 1994. Cell cycle control and cancer. Science 266:1821-1828.
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
30
-
-
0022385486
-
Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations
-
Hill, A., and R. Schimke. 1985. Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations. Cancer Res. 45:5050-5057.
-
(1985)
Cancer Res.
, vol.45
, pp. 5050-5057
-
-
Hill, A.1
Schimke, R.2
-
31
-
-
0029897210
-
Sensitivity and selectivity of the p53-mediated DNA damage sensor
-
Huang, L.-C., K. C. Clarkin, and G. M. Wahl. 1996. Sensitivity and selectivity of the p53-mediated DNA damage sensor. Proc. Natl. Acad. Sci. USA 93:4827-4832.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4827-4832
-
-
Huang, L.-C.1
Clarkin, K.C.2
Wahl, G.M.3
-
32
-
-
0031012977
-
Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53
-
Hundley, J. E., S. K. Koester, D. A. Troyer, S. G. Hilsenbeck, M. A. Subler, and J. J. Windle. 1997. Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53. Mol. Cell. Biol. 17:723-731.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 723-731
-
-
Hundley, J.E.1
Koester, S.K.2
Troyer, D.A.3
Hilsenbeck, S.G.4
Subler, M.A.5
Windle, J.J.6
-
33
-
-
0022445768
-
Changes in the phenotype of human small cell lung cancer cell lines after transfection and expression of the c-myc proto-oncogene
-
Johnson, B. E., J. Battey, I. Linnoila, K. L. Becker, R. W. Makuch, R. H. Snider, D. N. Carney, and J. D. Minna. 1986. Changes in the phenotype of human small cell lung cancer cell lines after transfection and expression of the c-myc proto-oncogene. J. Clin. Invest. 78:525-32.
-
(1986)
J. Clin. Invest.
, vol.78
, pp. 525-532
-
-
Johnson, B.E.1
Battey, J.2
Linnoila, I.3
Becker, K.L.4
Makuch, R.W.5
Snider, R.H.6
Carney, D.N.7
Minna, J.D.8
-
34
-
-
0027491775
-
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
-
Johnson, D. G., J. K. Schwarz, W. D. Cress, and J. R. Nevins. 1993. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature 365:349-352.
-
(1993)
Nature
, vol.365
, pp. 349-352
-
-
Johnson, D.G.1
Schwarz, J.K.2
Cress, W.D.3
Nevins, J.R.4
-
35
-
-
0020530971
-
Rapid spontaneous dihydrofolate reductase gene amplification shown by fluorescence-activated cell sorting
-
Johnston, R., S. Beverley, and R. Schimke. 1983. Rapid spontaneous dihydrofolate reductase gene amplification shown by fluorescence-activated cell sorting. Proc. Natl. Acad. Sci. USA 80:3711-3715.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 3711-3715
-
-
Johnston, R.1
Beverley, S.2
Schimke, R.3
-
36
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxiatelangiectasia
-
Kastan, M. B., Q. Zhan, W. S. El-Deiry, F. Carrier, T. Jacks, W. V. Walsh, B. S. Plunkett, B. Vogelstein, and A. J. Fornace. 1992. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxiatelangiectasia. Cell 71:587-597.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace, A.J.9
-
37
-
-
0026656853
-
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
-
Kuerbitz, S. J., B. S. Plunkett, W. V. Walsh, and M. B. Kastan. 1992. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA 89:7491-7495.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7491-7495
-
-
Kuerbitz, S.J.1
Plunkett, B.S.2
Walsh, W.V.3
Kastan, M.B.4
-
38
-
-
0021814288
-
Cellular and clinical pharmacology of low-dose ara-C
-
Kufe, D. W., J. D. Griffin, and D. R. Spriggs. 1985. Cellular and clinical pharmacology of low-dose ara-C. Semin. Oncol. 2(Suppl. 3):200-207.
-
(1985)
Semin. Oncol.
, vol.2
, Issue.3 SUPPL.
, pp. 200-207
-
-
Kufe, D.W.1
Griffin, J.D.2
Spriggs, D.R.3
-
39
-
-
0027982007
-
Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells
-
Kuo, M. T., R. C. Vyas, L. X. Jiang, and W. N. Hittelman. 1994. Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells. Mol. Cell. Biol. 14:5202-5211.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 5202-5211
-
-
Kuo, M.T.1
Vyas, R.C.2
Jiang, L.X.3
Hittelman, W.N.4
-
40
-
-
0029112238
-
Viability of wild type p53-containing and p53-deficient tumor cells following anticancer treatment: The use of human papillomavirus E6 to target p53
-
Labrecque, S., and G. J. Matlashewski. 1995. Viability of wild type p53-containing and p53-deficient tumor cells following anticancer treatment: the use of human papillomavirus E6 to target p53. Oncogene 11:387-392.
-
(1995)
Oncogene
, vol.11
, pp. 387-392
-
-
Labrecque, S.1
Matlashewski, G.J.2
-
41
-
-
0029038135
-
Apoptosis, cancer and the p53 tumour suppressor gene
-
Lee, J. M., and A. Bernstein. 1995. Apoptosis, cancer and the p53 tumour suppressor gene. Cancer Metastasis Rev. 14:149-161.
-
(1995)
Cancer Metastasis Rev.
, vol.14
, pp. 149-161
-
-
Lee, J.M.1
Bernstein, A.2
-
42
-
-
0028827582
-
Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines
-
Li, C. Y., H. Nagasawa, W. K. Dahlberg, and J. B. Little. 1995. Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines. Oncogene 11:1885-1892.
-
(1995)
Oncogene
, vol.11
, pp. 1885-1892
-
-
Li, C.Y.1
Nagasawa, H.2
Dahlberg, W.K.3
Little, J.B.4
-
43
-
-
0006889222
-
Accumulation of DNA strand breaks and methotrexate cytotoxicity
-
Li, J. C., and E. Kaminskas. 1984. Accumulation of DNA strand breaks and methotrexate cytotoxicity. Proc. Natl. Acad. Sci. USA 81:5694-5698.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 5694-5698
-
-
Li, J.C.1
Kaminskas, E.2
-
44
-
-
0028871672
-
Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines
-
Li, W., J. Fan, D. Hochhauser, D. Banerjee, Z. Zielinski, A. Almasan, Y. Yin, R. Kelly, G. M. Wahl and J. R. Bertino. 1995. Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines. Proc. Natl. Acad. Sci. USA 92:10436-10440.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10436-10440
-
-
Li, W.1
Fan, J.2
Hochhauser, D.3
Banerjee, D.4
Zielinski, Z.5
Almasan, A.6
Yin, Y.7
Kelly, R.8
Wahl, G.M.9
Bertino, J.R.10
-
45
-
-
0029964158
-
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage
-
Linke, S. P., K. C. Clarkin, L. A. Di, A. Tsou, and G. M. Wahl. 1996. A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes Dev. 10:934-947.
-
(1996)
Genes Dev.
, vol.10
, pp. 934-947
-
-
Linke, S.P.1
Clarkin, K.C.2
Di, L.A.3
Tsou, A.4
Wahl, G.M.5
-
46
-
-
0028990145
-
Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status
-
Little, J. B., H. Nagasawa, P. C. Keng, Y. Yu, and C. Y. Li. 1995. Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status. J. Biol. Chem. 270:11033-11036.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11033-11036
-
-
Little, J.B.1
Nagasawa, H.2
Keng, P.C.3
Yu, Y.4
Li, C.Y.5
-
47
-
-
0026801062
-
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
-
Livingstone, L. R., A. White, J. Sprouse, E. Livanos, T. Jacks, and T. D. Tisty. 1992. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70:923-935.
-
(1992)
Cell
, vol.70
, pp. 923-935
-
-
Livingstone, L.R.1
White, A.2
Sprouse, J.3
Livanos, E.4
Jacks, T.5
Tisty, T.D.6
-
48
-
-
0027152244
-
Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells
-
Ma, C., S. Martin, B. Trask, and J. L. Hamlin. 1993. Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells. Genes Dev. 7:605-620.
-
(1993)
Genes Dev.
, vol.7
, pp. 605-620
-
-
Ma, C.1
Martin, S.2
Trask, B.3
Hamlin, J.L.4
-
49
-
-
0027380346
-
Delayed chromosomal instability induced by DNA damage
-
Marder, B. A., and W. F. Morgan. 1993. Delayed chromosomal instability induced by DNA damage. Mol. Cell. Biol. 13:6667-6677.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6667-6677
-
-
Marder, B.A.1
Morgan, W.F.2
-
50
-
-
0021715393
-
The significance of responses of the genome to challenge
-
McClintock, B. 1984. The significance of responses of the genome to challenge. Science 226:792-801.
-
(1984)
Science
, vol.226
, pp. 792-801
-
-
McClintock, B.1
-
51
-
-
0018682878
-
Role of thymidylate synthetase activity in development of methotrexate cytotoxicity
-
Moran, R. G., M. Mulkins, and C. Heidelberger. 1979. Role of thymidylate synthetase activity in development of methotrexate cytotoxicity. Proc. Natl. Acad. Sci. USA 76:5924-5928.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 5924-5928
-
-
Moran, R.G.1
Mulkins, M.2
Heidelberger, C.3
-
52
-
-
0020443654
-
Kinetics of N-(phosphonacetyl)-L-aspartate and pyrazofurin depletion of pyrimidine ribonucleotide and deoxyribonucleotide pools and their relationship to nucleic acid synthesis in intact and permeabilized cells
-
Moyer, J. D., P. A. Smith, E. J. Levy, and R. E. Handschumacher. 1982. Kinetics of N-(phosphonacetyl)-L-aspartate and pyrazofurin depletion of pyrimidine ribonucleotide and deoxyribonucleotide pools and their relationship to nucleic acid synthesis in intact and permeabilized cells. Cancer Res. 42:4525-4531.
-
(1982)
Cancer Res.
, vol.42
, pp. 4525-4531
-
-
Moyer, J.D.1
Smith, P.A.2
Levy, E.J.3
Handschumacher, R.E.4
-
53
-
-
0028986606
-
Relationship between radiation-induced G1 phase arrest and p53 function in human tumor cells
-
Nagasawa, H., C. Y. Li, C. G. Maki, A. C. Imrich, and J. B. Little. 1995. Relationship between radiation-induced G1 phase arrest and p53 function in human tumor cells. Cancer Res. 55:1842-1846.
-
(1995)
Cancer Res.
, vol.55
, pp. 1842-1846
-
-
Nagasawa, H.1
Li, C.Y.2
Maki, C.G.3
Imrich, A.C.4
Little, J.B.5
-
54
-
-
0028204160
-
DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways
-
Nelson, W. G., and M. B. Kastan. 1994. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell. Biol. 14:1815-1823.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1815-1823
-
-
Nelson, W.G.1
Kastan, M.B.2
-
55
-
-
0028204160
-
DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways
-
Nelson, W. G., and M. B. Kastan. 1994. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell. Biol. 14:1815-1823.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1815-1823
-
-
Nelson, W.G.1
Kastan, M.B.2
-
57
-
-
0029873705
-
Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles
-
Poupon, M. F., K. A. Smith, O. B. Chernova, C. Gilbert, and G. R. Stark. 1996. Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles. Mol. Biol. Cell 7:345-354.
-
(1996)
Mol. Biol. Cell
, vol.7
, pp. 345-354
-
-
Poupon, M.F.1
Smith, K.A.2
Chernova, O.B.3
Gilbert, C.4
Stark, G.R.5
-
58
-
-
0016373845
-
Characterization of a newly derived human sarcoma cell line (HT-1080)
-
Rasheed, S. 1974. Characterization of a newly derived human sarcoma cell line (HT-1080). Cancer 33:1027-1033.
-
(1974)
Cancer
, vol.33
, pp. 1027-1033
-
-
Rasheed, S.1
-
59
-
-
0025330850
-
Chromosomal destabilization during gene amplification
-
Ruiz, J. C., and G. M. Wahl. 1990. Chromosomal destabilization during gene amplification. Mol. Cell. Biol. 10:3056-3066.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 3056-3066
-
-
Ruiz, J.C.1
Wahl, G.M.2
-
60
-
-
0025639158
-
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
-
Scheffner, M., B. A. Werness, J. M. Huibregtse, A. J. Levine, and P. M. Howley. 1990. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63:1129-1136.
-
(1990)
Cell
, vol.63
, pp. 1129-1136
-
-
Scheffner, M.1
Werness, B.A.2
Huibregtse, J.M.3
Levine, A.J.4
Howley, P.M.5
-
61
-
-
0023940788
-
Gene amplification in cultured cells
-
Schimke, R. T. 1988. Gene amplification in cultured cells. J. Biol. Chem. 263:5989-5992.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 5989-5992
-
-
Schimke, R.T.1
-
62
-
-
13844320300
-
Gene amplification; what are we learning?
-
Schimke, R. T. 1992. Gene amplification; what are we learning? Mutat. Res. 276:145-149.
-
(1992)
Mutat. Res.
, vol.276
, pp. 145-149
-
-
Schimke, R.T.1
-
63
-
-
0022388606
-
Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
-
Seeger, K. C., G. M. Brodeur, H. Sather, A. Dalton, S. E. Siegel, K. Y. Wong, and D. Hammond. 1985. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N. Engl. J. Med. 313:1111-1116.
-
(1985)
N. Engl. J. Med.
, vol.313
, pp. 1111-1116
-
-
Seeger, K.C.1
Brodeur, G.M.2
Sather, H.3
Dalton, A.4
Siegel, S.E.5
Wong, K.Y.6
Hammond, D.7
-
64
-
-
0024405687
-
Enhancement of the frequency of methotrexate resistance by G-radiation in Chinese hamster ovary and mouse 3T6 cells
-
Sharma, R. C., and R. T. Schimke. 1989. Enhancement of the frequency of methotrexate resistance by G-radiation in Chinese hamster ovary and mouse 3T6 cells. Cancer Res. 49:3861-3866.
-
(1989)
Cancer Res.
, vol.49
, pp. 3861-3866
-
-
Sharma, R.C.1
Schimke, R.T.2
-
65
-
-
0029849620
-
Cancer cell cycles
-
Sherr, C. J. 1996. Cancer cell cycles. Science 274:1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
66
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon, D. J., W. Godolphin, L. A. Jones, J. A. Holt, S. G. Wong, D. E. Keith, W. J. Levin, S. G. Stuart, J. Udove, A. Ullrich, and M. Press. 1989. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244:707-712.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
Press, M.11
-
67
-
-
0029654314
-
Regulation and mechanisms of gene amplification
-
Smith, K. A., M. L. Agarwal, M. V. Chernov, O. B. Chernova, Y. Deguchi, Y. Ishizaka, T. E. Patterson, M. F. Poupon, and G. R. Stark. 1995. Regulation and mechanisms of gene amplification. Philos. Trans. R. Soc. London B 347:49-56.
-
(1995)
Philos. Trans. R. Soc. London B
, vol.347
, pp. 49-56
-
-
Smith, K.A.1
Agarwal, M.L.2
Chernov, M.V.3
Chernova, O.B.4
Deguchi, Y.5
Ishizaka, Y.6
Patterson, T.E.7
Poupon, M.F.8
Stark, G.R.9
-
68
-
-
0031055329
-
Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: Carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged
-
Smith, K. A., O. B. Chernova, R. P. Groves, M. B. Stark, J. L. Martinez, J. N. Davidson, J. M. Trent, T. E. Patterson, A. Agarwal, P. Duncan, M. L. Agarwal, and G. R. Stark. 1997. Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged. Proc. Natl. Acad. Sci. USA 94:1816-1821.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1816-1821
-
-
Smith, K.A.1
Chernova, O.B.2
Groves, R.P.3
Stark, M.B.4
Martinez, J.L.5
Davidson, J.N.6
Trent, J.M.7
Patterson, T.E.8
Agarwal, A.9
Duncan, P.10
Agarwal, M.L.11
Stark, G.R.12
-
69
-
-
0026636626
-
Fusions near telomeres occur very early in the amplification of CAD genes in Syrian hamster cells
-
Smith, K. A., M. B. Stark, P. A. Gorman, and G. R. Stark. 1992. Fusions near telomeres occur very early in the amplification of CAD genes in Syrian hamster cells. Proc. Natl. Acad. Sci. USA 89:5427-5431.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5427-5431
-
-
Smith, K.A.1
Stark, M.B.2
Gorman, P.A.3
Stark, G.R.4
-
70
-
-
0022835788
-
Microinjection of the ras oncogene protein into nonestablished rat embryo fibroblasts
-
Sullivan, N. F., R. W. Sweet, M. Rosenberg, and J. R. Feramisco. 1986. Microinjection of the ras oncogene protein into nonestablished rat embryo fibroblasts. Cancer Res. 6427-6432
-
(1986)
Cancer Res.
, vol.6427-6432
-
-
Sullivan, N.F.1
Sweet, R.W.2
Rosenberg, M.3
Feramisco, J.R.4
-
71
-
-
0016242582
-
N-(Phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture
-
Swyryd, E. A., S. S. Seaver, and G. R. Stark. 1974. N-(Phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture. J. Biol. Chem. 249:6945-6950.
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 6945-6950
-
-
Swyryd, E.A.1
Seaver, S.S.2
Stark, G.R.3
-
72
-
-
0009605722
-
Enhanced frequency of generation of methotrexate resistance and gene amplification in cultured mouse and hamster cell lines
-
R. T. Schimke (ed.), Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
-
Tlsty, T., P. C. Brown, R. Johnston, and R. T. Schimke. 1982. Enhanced frequency of generation of methotrexate resistance and gene amplification in cultured mouse and hamster cell lines, p. 231-238. In R. T. Schimke (ed.), Gene amplification. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
-
(1982)
Gene Amplification
, pp. 231-238
-
-
Tlsty, T.1
Brown, P.C.2
Johnston, R.3
Schimke, R.T.4
-
73
-
-
0025253116
-
Normal diploid human and rodent cells lack a detectable 0frequency of gene amplification
-
Tlsty, T. D. 1990. Normal diploid human and rodent cells lack a detectable 0frequency of gene amplification. Proc. Natl. Acad. Sci. USA 87:3132-3136:
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 3132-3136
-
-
Tlsty, T.D.1
-
74
-
-
0024357990
-
Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbruck fluctuation analysis
-
Tlsty, T. D., B. H. Margolin and K. Lum. 1989. Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbruck fluctuation analysis. Proc. Natl. Acad. Sci. USA 86:9441-9445.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 9441-9445
-
-
Tlsty, T.D.1
Margolin, B.H.2
Lum, K.3
-
75
-
-
0019480401
-
Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: Possible mechanisms and relevance to tumor promotion
-
Varshavsky, A. 1981. Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: possible mechanisms and relevance to tumor promotion. Cell 25:561-572.
-
(1981)
Cell
, vol.25
, pp. 561-572
-
-
Varshavsky, A.1
-
76
-
-
2642694505
-
Is gene amplification inducible?
-
R. Dulbecco, V. De Vita, L. Santi, and L. Zardi (ed.), Humana Press, Totowa, N.J.
-
Wahl, G., P. Gaudray, S. Carroll, and N. Proctor. 1986. Is gene amplification inducible?, p. 71-98. In R. Dulbecco, V. De Vita, L. Santi, and L. Zardi (ed.), Cancer frontiers, proceedings of the Second International Conference on Progress in Cancer Research. Humana Press, Totowa, N.J.
-
(1986)
Cancer Frontiers, Proceedings of the Second International Conference on Progress in Cancer Research
, pp. 71-98
-
-
Wahl, G.1
Gaudray, P.2
Carroll, S.3
Proctor, N.4
-
77
-
-
0025271203
-
Association of human papillomavirus types 16 and 18 E6 proteins with p53
-
Werness, B. A., A. J. Levine, and P. M. Howley. 1990. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science 248:76-79.
-
(1990)
Science
, vol.248
, pp. 76-79
-
-
Werness, B.A.1
Levine, A.J.2
Howley, P.M.3
-
78
-
-
0028034571
-
Drug-specific rearrangements of chromosome 12 in hydroxyurea-resistant mouse SEWA cells: Support for chromosomal breakage model of gene amplification
-
Wettergren, Y., A. Kullberg, and G. Levan. 1994. Drug-specific rearrangements of chromosome 12 in hydroxyurea-resistant mouse SEWA cells: support for chromosomal breakage model of gene amplification. Somat. Cell Mol. Genet. 20:267-285.
-
(1994)
Somat. Cell Mol. Genet.
, vol.20
, pp. 267-285
-
-
Wettergren, Y.1
Kullberg, A.2
Levan, G.3
-
79
-
-
0028331229
-
Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins
-
White, A. E., E. M. Livanos, and T. D. Tlsty. 1994. Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. Genes Dev. 8:666-677.
-
(1994)
Genes Dev.
, vol.8
, pp. 666-677
-
-
White, A.E.1
Livanos, E.M.2
Tlsty, T.D.3
-
80
-
-
0026018901
-
A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration
-
Windle, B., B. W. Draper, Y. X. Yin, S. O'Gorman and G. M. Wahl. 1991. A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration. Genes Dev. 5:160-174.
-
(1991)
Genes Dev.
, vol.5
, pp. 160-174
-
-
Windle, B.1
Draper, B.W.2
Yin, Y.X.3
O'Gorman, S.4
Wahl, G.M.5
-
81
-
-
0242672936
-
Molecular dissection of mammalian gene amplification: New mechanistic insights revealed by analyses of very early events
-
Windle, B. E., and G. M. Wahl. 1992. Molecular dissection of mammalian gene amplification: new mechanistic insights revealed by analyses of very early events. Mutat. Res. 276:199-224.
-
(1992)
Mutat. Res.
, vol.276
, pp. 199-224
-
-
Windle, B.E.1
Wahl, G.M.2
-
82
-
-
0025254476
-
DNA amplification is rare in normal human cells
-
Wright, J. A., H. S. Smith, F. M. Watt, M. C. Hancock, D. L. Hudson, and G. R. Stark. 1990. DNA amplification is rare in normal human cells. Proc. Natl. Acad. Sci. USA 87:1791-1795.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 1791-1795
-
-
Wright, J.A.1
Smith, H.S.2
Watt, F.M.3
Hancock, M.C.4
Hudson, D.L.5
Stark, G.R.6
-
83
-
-
0028222124
-
p53 and E2F-1 cooperate to mediate apoptosis
-
Wu, X., and A. J. Levine. 1994. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA 91:3602-3606.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3602-3606
-
-
Wu, X.1
Levine, A.J.2
-
84
-
-
0021659679
-
Human dihydrofolate reductase gene organization. Extensive conservation of the G + C-rich 5′ non-coding sequence and strong intron size divergence from homologous mammalian genes
-
Yang, J. K., J. N. Masters, and G. Attardi. 1984. Human dihydrofolate reductase gene organization. Extensive conservation of the G + C-rich 5′ non-coding sequence and strong intron size divergence from homologous mammalian genes. J. Mol. Biol. 176:169-187.
-
(1984)
J. Mol. Biol.
, vol.176
, pp. 169-187
-
-
Yang, J.K.1
Masters, J.N.2
Attardi, G.3
-
85
-
-
0026801977
-
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
-
Yin, Y., M. A. Tainsky, F. Z. Bischoff, L. C. Strong, and G. M. Wahl. 1992. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70:937-948.
-
(1992)
Cell
, vol.70
, pp. 937-948
-
-
Yin, Y.1
Tainsky, M.A.2
Bischoff, F.Z.3
Strong, L.C.4
Wahl, G.M.5
|