Induction of murine O6-alkylguanine-DNA-alkyltransferase in response to ionising radiation is p53 gene dose dependent

Oncogene

Volumn 12, Issue 3, 1996, Pages 693-697

  Rafferty, Joseph A ^a   Clarke, Alan R ^b   Sellappan, Dhanalakshmi ^a   Koref, Mauro Santibanez ^c   Frayling, Ian M ^b   Margison, Geoffrey P ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Animal model; ATase; DNA repair induction; p53

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; PROTEIN P53; TRANSCRIPTION FACTOR; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; METHYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME KINETICS; GAMMA IRRADIATION; GENE EXPRESSION; HETEROZYGOTE; IONIZING RADIATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; BIOSYNTHESIS; BRAIN; C57BL MOUSE; CELL CYCLE; COMPARATIVE STUDY; ENZYMOLOGY; GAMMA RADIATION; GENE DOSAGE; KIDNEY; KINETICS; LIVER; LUNG; MOUSE MUTANT; MOUSE STRAIN; RADIATION EXPOSURE; SPECIES DIFFERENCE; TUMOR SUPPRESSOR GENE; WHOLE BODY RADIATION;

ANIMALS; APOPTOSIS; BRAIN; CELL CYCLE; ENZYME INDUCTION; GAMMA RAYS; GENE DOSAGE; GENES, P53; HETEROZYGOTE; KIDNEY; KINETICS; LIVER; LUNG; MALE; METHYLTRANSFERASES; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; MODELS, BIOLOGICAL; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; WHOLE-BODY IRRADIATION;

ANIMALIA; MURINAE;

EID: 0029670607     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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