Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint

Oncogene

Volumn 18, Issue 24, 1999, Pages 3553-3563

  Saintigny, Yannick ^a   Rouillard, Danielle ^b   Chaput, Brigitte ^a   Soussi, Thierry ^b   Lopez, Bernard S ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^b INSTITUT CURIE   (France)

Author keywords

Cell cycle; Homologous recombination; p53; Radiation

Indexed keywords

MUTANT PROTEIN; PROTEIN P53;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; GENETIC RECOMBINATION; L CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CONFORMATION; RADIATION; TRANSACTIVATION;

ANIMALS; CELL DEATH; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA, SINGLE-STRANDED; G1 PHASE; GAMMA RAYS; MICE; MUTATION; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RADIATION DOSAGE; RECOMBINATION, GENETIC; REPETITIVE SEQUENCES, NUCLEIC ACID; S PHASE; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0033578066     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202941     Document Type: Article

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