-
1
-
-
0038811884
-
Bacterial ribosomal subunit assembly is an antibiotic target
-
CHAMPNEY W S 2003 Bacterial ribosomal subunit assembly is an antibiotic target. Curr Top Med Chem 3: 929-947
-
(2003)
Curr Top Med Chem
, vol.3
, pp. 929-947
-
-
Champney, W.S.1
-
3
-
-
0034637111
-
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution
-
BAN N, NISSEN P, HANSEN J, MOORE P B, STEITZ T A 2000 The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science 289: 905-920
-
(2000)
Science
, vol.289
, pp. 905-920
-
-
Ban, N.1
Nissen, P.2
Hansen, J.3
Moore, P.B.4
Steitz, T.A.5
-
4
-
-
0034699519
-
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
-
CARTER A P, CLEMONS W M, BRODERSEN D E, MORGAN-WARREN R J, WIMBERLY B T, RAMAKRISHNAN V 2000 Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature 407: 340-348
-
(2000)
Nature
, vol.407
, pp. 340-348
-
-
Carter, A.P.1
Clemons, W.M.2
Brodersen, D.E.3
Morgan-Warren, R.J.4
Wimberly, B.T.5
Ramakrishnan, V.6
-
5
-
-
0035977093
-
High resolution structure of the large ribosomal subunit from a mesophilic eubacterium
-
HARMS J, SCHLUENZEN F, ZARIVACH R, BASHAN A, GAT S, AGMON I, BARTELS H, FRANCESCHI F, YONATH A 2001 High resolution structure of the large ribosomal subunit from a mesophilic eubacterium. Cell 107: 679-688
-
(2001)
Cell
, vol.107
, pp. 679-688
-
-
Harms, J.1
Schluenzen, F.2
Zarivach, R.3
Bashan, A.4
Gat, S.5
Agmon, I.6
Bartels, H.7
Franceschi, F.8
Yonath, A.9
-
6
-
-
0035805213
-
Crystal structure of the ribosome at 5.5 A resolution
-
YUSUPOV M M, YUSUPOVA G Z, BAUCOM A, LIEBERMAN K, EARNEST T N, CATE J H, NOLLER H F 2001 Crystal structure of the ribosome at 5.5 A resolution. Science 292: 883-896
-
(2001)
Science
, vol.292
, pp. 883-896
-
-
Yusupov, M.M.1
Yusupova, G.Z.2
Baucom, A.3
Lieberman, K.4
Earnest, T.N.5
Cate, J.H.6
Noller, H.F.7
-
7
-
-
0036342198
-
The structures of four macrolide antibiotics bound to the large ribosomal subunit
-
HANSEN J L, IPPOLITO J A, BAN N, NISSEN P, MOORE P B, STEITZ T A 2002 The structures of four macrolide antibiotics bound to the large ribosomal subunit. Mol Cell 10: 117-128
-
(2002)
Mol Cell
, vol.10
, pp. 117-128
-
-
Hansen, J.L.1
Ippolito, J.A.2
Ban, N.3
Nissen, P.4
Moore, P.B.5
Steitz, T.A.6
-
8
-
-
0035950132
-
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
-
SCHLUNZEN F, ZARIVACH R, HARMS J, BASHAN A, TOCILJ A, ALBRECHT R, YONATH A, FRANCESCHI F 2001 Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature 413: 814-821
-
(2001)
Nature
, vol.413
, pp. 814-821
-
-
Schlunzen, F.1
Zarivach, R.2
Harms, J.3
Bashan, A.4
Tocilj, A.5
Albrecht, R.6
Yonath, A.7
Franceschi, F.8
-
9
-
-
0037334850
-
Structural basis for the antibiotic activity of ketolides and azalides
-
SCHLUNZEN F, HARMS J M, FRANCESCHI F, HANSEN H A, BARTELS H, ZARIVACH R, YONATH A 2003 Structural basis for the antibiotic activity of ketolides and azalides. Structure (Camb) 11: 329-338
-
(2003)
Structure (Camb)
, vol.11
, pp. 329-338
-
-
Schlunzen, F.1
Harms, J.M.2
Franceschi, F.3
Hansen, H.A.4
Bartels, H.5
Zarivach, R.6
Yonath, A.7
-
10
-
-
0042658199
-
RNA, the first macromolecular catalyst: The ribosome is a ribozyme
-
STEITZ T A, MOORE P B 2003 RNA, the first macromolecular catalyst: the ribosome is a ribozyme. Trends Biochem Sci 28: 411-418
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 411-418
-
-
Steitz, T.A.1
Moore, P.B.2
-
14
-
-
0002841715
-
Properties of modified nucleosides
-
Grosjean H, Benne R (ed). ASM Press, Washington DC
-
DAVIS D R 1998 Properties of modified nucleosides. In: Grosjean H, Benne R (ed) Modification and Editing of RNA. ASM Press, Washington DC, p 85
-
(1998)
Modification and Editing of RNA
, pp. 85
-
-
Davis, D.R.1
-
15
-
-
0033950924
-
Mapping posttranscriptional modifications in 5S ribosomal RNA by MALDI mass spectrometry
-
KIRPEKAR F, DOUTHWAITE S, ROEPSTORFF P 2000 Mapping posttranscriptional modifications in 5S ribosomal RNA by MALDI mass spectrometry. RNA 6: 296-306
-
(2000)
RNA
, vol.6
, pp. 296-306
-
-
Kirpekar, F.1
Douthwaite, S.2
Roepstorff, P.3
-
16
-
-
0036629250
-
rRNA modifications and ribosome function
-
DECATUR W A, FOURNIER M J 2002 rRNA modifications and ribosome function. Trends Biochem Sci 27: 344-351
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 344-351
-
-
Decatur, W.A.1
Fournier, M.J.2
-
17
-
-
0004103059
-
-
ASM Press, Washington DC
-
GARRETT RA, DOUTHWAITE S R, LILJAS A, MATHESON A T, MOORE P B, NOLLER H F 2000 The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions ASM Press, Washington DC.
-
(2000)
The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions
-
-
Garrett, R.A.1
Douthwaite, S.R.2
Liljas, A.3
Matheson, A.T.4
Moore, P.B.5
Noller, H.F.6
-
18
-
-
0031802176
-
A single 16S ribosomal RNA substitution is responsible for resistance to amikacin and other 2-deoxystreptamine aminoglycosides in Mycobacterium abscessus and Mycobacterium chelonae
-
PRAMMANANAN T, SANDER P, BROWN B A, FRISCHKORN K, ONYI G O, ZHANG Y, BOTTGER E C, WALLACE R J 1998 A single 16S ribosomal RNA substitution is responsible for resistance to amikacin and other 2-deoxystreptamine aminoglycosides in Mycobacterium abscessus and Mycobacterium chelonae. J Infect Dis 177: 1573-1581
-
(1998)
J Infect Dis
, vol.177
, pp. 1573-1581
-
-
Prammananan, T.1
Sander, P.2
Brown, B.A.3
Frischkorn, K.4
Onyi, G.O.5
Zhang, Y.6
Bottger, E.C.7
Wallace, R.J.8
-
20
-
-
0037303518
-
Macrolide antibiotic interaction and resistance on the bacterial ribosome
-
POEHLSGAARD J, DOUTHWAITE S 2003 Macrolide antibiotic interaction and resistance on the bacterial ribosome. Curr Opin Investig Drugs 4: 140-148
-
(2003)
Curr Opin Investig Drugs
, vol.4
, pp. 140-148
-
-
Poehlsgaard, J.1
Douthwaite, S.2
-
21
-
-
0028963496
-
Erythromycin resistance by ribosome modification
-
WEISBLUM B 1995 Erythromycin resistance by ribosome modification. Antimicrob Agents Chemother 39: 577-585
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 577-585
-
-
Weisblum, B.1
-
22
-
-
0025821199
-
Bacterial resistance to macrolide, lincosamide, and streptogramin antibiotics by target modification
-
LECLERCQ R, COURVALIN P 1991 Bacterial resistance to macrolide, lincosamide, and streptogramin antibiotics by target modification. Antimicrob Agents Chemother 35: 1267-1272
-
(1991)
Antimicrob Agents Chemother
, vol.35
, pp. 1267-1272
-
-
Leclercq, R.1
Courvalin, P.2
-
23
-
-
0028914553
-
Insights into erythromycin action from studies of its activity as inducer of resistance
-
WEISBLUM B 1995 Insights into erythromycin action from studies of its activity as inducer of resistance. Antimicrob Agents Chemother 39: 797-805
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 797-805
-
-
Weisblum, B.1
-
24
-
-
0032762933
-
Nomenclature for macrolide and macrolide-lincosamide-streptogramin B resistance determinants
-
ROBERTS M C, SUTCLIFFE J, COURVALIN P, JENSEN L B, ROOD J, SEPPALA H 1999 Nomenclature for macrolide and macrolide-lincosamide-streptogramin B resistance determinants. Antimicrob Agents Chemother 43: 2823-2830
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 2823-2830
-
-
Roberts, M.C.1
Sutcliffe, J.2
Courvalin, P.3
Jensen, L.B.4
Rood, J.5
Seppala, H.6
-
25
-
-
0032821318
-
Negative in vitro selection identifies the rRNA recognition motif for ErmE methyltransferase
-
NIELSEN A K, DOUTHWAITE S, VESTER B 1999 Negative in vitro selection identifies the rRNA recognition motif for ErmE methyltransferase. RNA 5: 1034-1041
-
(1999)
RNA
, vol.5
, pp. 1034-1041
-
-
Nielsen, A.K.1
Douthwaite, S.2
Vester, B.3
-
26
-
-
0032902691
-
Core sequence in the RNA motif recognized by the ErmE methyltransferase revealed by relaxing the fidelity of the enzyme for its target
-
HANSEN L H, VESTER B, DOUTHWAITE S 1999 Core sequence in the RNA motif recognized by the ErmE methyltransferase revealed by relaxing the fidelity of the enzyme for its target. RNA 5: 93-101
-
(1999)
RNA
, vol.5
, pp. 93-101
-
-
Hansen, L.H.1
Vester, B.2
Douthwaite, S.3
-
27
-
-
0033582723
-
ErmE methyltransferase recognizes features of the primary and secondary structure in a motif within domain V of 23 S rRNA
-
VILLSEN I D, VESTER B, DOUTHWAITE S 1999 ErmE methyltransferase recognizes features of the primary and secondary structure in a motif within domain V of 23 S rRNA. J Mol Biol 286: 365-374
-
(1999)
J Mol Biol
, vol.286
, pp. 365-374
-
-
Villsen, I.D.1
Vester, B.2
Douthwaite, S.3
-
28
-
-
0030902818
-
Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance
-
YU L, PETROS A M, SCHNUCHEL A, ZHONG P, SEVERIN J M, WALTER K, HOLZMAN T F, FESIK S W 1997 Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance. Nat Struct Biol 4: 483-489
-
(1997)
Nat Struct Biol
, vol.4
, pp. 483-489
-
-
Yu, L.1
Petros, A.M.2
Schnuchel, A.3
Zhong, P.4
Severin, J.M.5
Walter, K.6
Holzman, T.F.7
Fesik, S.W.8
-
29
-
-
0032546573
-
Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria
-
BUSSIERE D E, MUCHMORE S W, DEALWIS C G, SCHLUCKEBIER G, NIENABER V L, EDALJI R P, WALTER K A, LADROR U S, HOLZMAN T F, ABAD-ZAPATERO C 1998 Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria. Biochemistry 37: 7103-7112
-
(1998)
Biochemistry
, vol.37
, pp. 7103-7112
-
-
Bussiere, D.E.1
Muchmore, S.W.2
Dealwis, C.G.3
Schluckebier, G.4
Nienaber, V.L.5
Edalji, R.P.6
Walter, K.A.7
Ladror, U.S.8
Holzman, T.F.9
Abad-Zapatero, C.10
-
30
-
-
0033522646
-
The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: Implications for the reaction mechanism
-
SCHLUCKEBIER G, ZHONG P, STEWART K D, KAVANAUGH T J, ABAD-ZAPATERO C 1999 The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism. J Mol Biol 289: 277-291
-
(1999)
J Mol Biol
, vol.289
, pp. 277-291
-
-
Schluckebier, G.1
Zhong, P.2
Stewart, K.D.3
Kavanaugh, T.J.4
Abad-Zapatero, C.5
-
31
-
-
0033302662
-
Comparison of protein structures reveals monophyletic origin of the AdoMet-dependent methyltransferase family and mechanistic convergence rather than recent differentiation of N4-cytosine and N6-adenine DNA methylation
-
BUJNICKI J M 1999 Comparison of protein structures reveals monophyletic origin of the AdoMet-dependent methyltransferase family and mechanistic convergence rather than recent differentiation of N4-cytosine and N6-adenine DNA methylation. In Silico Biol 1: 175-182
-
(1999)
In Silico Biol
, vol.1
, pp. 175-182
-
-
Bujnicki, J.M.1
-
32
-
-
0002450504
-
Structure and Evolution of AdoMet-Dependent Methyltransferases
-
Cheng X, Blumenthal R M (ed). World Scientific Inc., Singapore
-
FAUMAN E B, BLUMENTHAL R M, CHENG X 1999 Structure and Evolution of AdoMet-Dependent Methyltransferases. In: Cheng X, Blumenthal R M (ed) S-adenosylmethionine-dependent methyltransferases: structures and functions. World Scientific Inc., Singapore, p 1
-
(1999)
S-adenosylmethionine-dependent Methyltransferases: Structures and Functions
, pp. 1
-
-
Fauman, E.B.1
Blumenthal, R.M.2
Cheng, X.3
-
33
-
-
0021158357
-
Structure of ribosomal RNA
-
NOLLER H F 1984 Structure of ribosomal RNA. Annu Rev Biochem 53: 119-162
-
(1984)
Annu Rev Biochem
, vol.53
, pp. 119-162
-
-
Noller, H.F.1
-
34
-
-
0021064473
-
Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics
-
SKINNER R, CUNDLIFFE E, SCHMIDT F J 1983 Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics. J Biol Chem 258: 12702-12706
-
(1983)
J Biol Chem
, vol.258
, pp. 12702-12706
-
-
Skinner, R.1
Cundliffe, E.2
Schmidt, F.J.3
-
36
-
-
0142138438
-
Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions
-
MARAVIC G, BUJNICKI J M, FEDER M, PONGOR S, FLOGEL M 2003 Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions. Nucleic Acids Res 31: 4941-4949
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 4941-4949
-
-
Maravic, G.1
Bujnicki, J.M.2
Feder, M.3
Pongor, S.4
Flogel, M.5
-
37
-
-
0033514427
-
Functional roles of the conserved aromatic amino acid residues at position 108 (motif IV) and position 196 (motif VIII) in base flipping and catalysis by the N6-adenine DNA methyltransferase from Thermus aquaticus
-
PUES H, BLEIMLING N, HOLZ B, WOLCKE J, WEINHOLD E 1999 Functional roles of the conserved aromatic amino acid residues at position 108 (motif IV) and position 196 (motif VIII) in base flipping and catalysis by the N6-adenine DNA methyltransferase from Thermus aquaticus. Biochemistry 38: 1426-1434
-
(1999)
Biochemistry
, vol.38
, pp. 1426-1434
-
-
Pues, H.1
Bleimling, N.2
Holz, B.3
Wolcke, J.4
Weinhold, E.5
-
38
-
-
0034746572
-
Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog
-
GOEDECKE K, PIGNOT M, GOODY R S, SCHEIDIG A J, WEINHOLD E 2001 Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog. Nat Struct Biol 8: 121-125
-
(2001)
Nat Struct Biol
, vol.8
, pp. 121-125
-
-
Goedecke, K.1
Pignot, M.2
Goody, R.S.3
Scheidig, A.J.4
Weinhold, E.5
-
39
-
-
0032504248
-
Functional roles of conserved amino acid residues in DNA methyltransferases investigated by site-directed mutagenesis of the EcoRV adenine-N6-methyltransferase
-
ROTH M, HELM-KRUSE S, FRIEDRICH T, JELTSCH A 1998 Functional roles of conserved amino acid residues in DNA methyltransferases investigated by site-directed mutagenesis of the EcoRV adenine-N6-methyltransferase. J Biol Chem 273: 17333-17342
-
(1998)
J Biol Chem
, vol.273
, pp. 17333-17342
-
-
Roth, M.1
Helm-Kruse, S.2
Friedrich, T.3
Jeltsch, A.4
-
40
-
-
0033593476
-
Mutational analysis of target base flipping by the EcoRV adenine-N6 DNA methyltransferase
-
JELTSCH A, ROTH M, FRIEDRICH T 1999 Mutational analysis of target base flipping by the EcoRV adenine-N6 DNA methyltransferase. J Mol Biol 285: 1121-1130
-
(1999)
J Mol Biol
, vol.285
, pp. 1121-1130
-
-
Jeltsch, A.1
Roth, M.2
Friedrich, T.3
-
41
-
-
1842418773
-
Mutational analysis of basic residues in the N-terminal part of the rRNA:m6A methyltransferase ErmC'
-
MARAVIC G, BUJNICKI J M, FLOEGEL M 2004 Mutational analysis of basic residues in the N-terminal part of the rRNA:m6A methyltransferase ErmC'. Folia Microbiol 49: 3-7
-
(2004)
Folia Microbiol
, vol.49
, pp. 3-7
-
-
Maravic, G.1
Bujnicki, J.M.2
Floegel, M.3
-
42
-
-
0042736455
-
Mutational analysis defines the roles of conserved amino acid residues in the predicted catalytic pocket of the rRNA:m6A methyltransferase ErmC'
-
MARAVIC G, FEDER M, PONGOR S, FLOGEL M, BUJNICKI J M 2003 Mutational analysis defines the roles of conserved amino acid residues in the predicted catalytic pocket of the rRNA:m6A methyltransferase ErmC'. J Mol Biol 332: 99-109
-
(2003)
J Mol Biol
, vol.332
, pp. 99-109
-
-
Maravic, G.1
Feder, M.2
Pongor, S.3
Flogel, M.4
Bujnicki, J.M.5
-
43
-
-
0037770202
-
Versatility of aminoglycosides and prospects for their future
-
VAKULENKO S B, MOBASHERY S 2003 Versatility of aminoglycosides and prospects for their future. Clin Microbiol Rev 16: 430-450
-
(2003)
Clin Microbiol Rev
, vol.16
, pp. 430-450
-
-
Vakulenko, S.B.1
Mobashery, S.2
-
44
-
-
0038811889
-
Aminoglycoside and its derivatives as ligands to target the ribosome
-
TOK J B, BI L 2003 Aminoglycoside and its derivatives as ligands to target the ribosome. Curr Top Med Chem 3: 1001-1019
-
(2003)
Curr Top Med Chem
, vol.3
, pp. 1001-1019
-
-
Tok, J.B.1
Bi, L.2
-
45
-
-
0023238983
-
Interaction of antibiotics with functional sites in 16S ribosomal RNA
-
MOAZED D, NOLLER H F 1987 Interaction of antibiotics with functional sites in 16S ribosomal RNA. Nature 327: 389-394
-
(1987)
Nature
, vol.327
, pp. 389-394
-
-
Moazed, D.1
Noller, H.F.2
-
46
-
-
0025733603
-
Ribosomal RNA and translation
-
NOLLER H F 1991 Ribosomal RNA and translation. Annu Rev Biochem 60: 191-227
-
(1991)
Annu Rev Biochem
, vol.60
, pp. 191-227
-
-
Noller, H.F.1
-
47
-
-
0029825658
-
Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic
-
FOURMY D, RECHT MI, BLANCHARD S C, PUGLISI J D 1996 Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic. Science 274: 1367-1371
-
(1996)
Science
, vol.274
, pp. 1367-1371
-
-
Fourmy, D.1
Recht, M.I.2
Blanchard, S.C.3
Puglisi, J.D.4
-
48
-
-
0032571359
-
Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA
-
FOURMY D, YOSHIZAWA S, PUGLISI J D 1998 Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA. J Mol Biol 277: 333-345
-
(1998)
J Mol Biol
, vol.277
, pp. 333-345
-
-
Fourmy, D.1
Yoshizawa, S.2
Puglisi, J.D.3
-
49
-
-
0032571306
-
Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 S rRNA
-
FOURMY D, RECHT M I, PUGLISI J D 1998 Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 S rRNA. J Mol Biol 277: 347-362
-
(1998)
J Mol Biol
, vol.277
, pp. 347-362
-
-
Fourmy, D.1
Recht, M.I.2
Puglisi, J.D.3
-
50
-
-
0032538956
-
Structural origins of gentamicin antibiotic action
-
YOSHIZAWA S, FOURMY D, PUGLISI J D 1998 Structural origins of gentamicin antibiotic action. EMBO 117: 6437-6448
-
(1998)
EMBO
, vol.117
, pp. 6437-6448
-
-
Yoshizawa, S.1
Fourmy, D.2
Puglisi, J.D.3
-
51
-
-
0035805229
-
Recognition of cognate transfer RNA by the 30S ribosomal subunit
-
OGLE J M, BRODERSEN D E, CLEMONS W M, JR., TARRY M J, CARTERA P, RAMAKRISHNAN V 2001 Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science 292: 897-902
-
(2001)
Science
, vol.292
, pp. 897-902
-
-
Ogle, J.M.1
Brodersen, D.E.2
Clemons Jr., W.M.3
Tarry, M.J.4
Cartera, P.5
Ramakrishnan, V.6
-
52
-
-
0034886697
-
Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site
-
VICENS Q, WESTHOF E 2001 Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site. Structure (Camb) 9: 647-658
-
(2001)
Structure (Camb)
, vol.9
, pp. 647-658
-
-
Vicens, Q.1
Westhof, E.2
-
53
-
-
0035986708
-
Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding a site
-
VICENS Q, WESTHOF E 2002 Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding a site. Chem Biol 9: 747-755
-
(2002)
Chem Biol
, vol.9
, pp. 747-755
-
-
Vicens, Q.1
Westhof, E.2
-
54
-
-
0037470560
-
Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide
-
VICENS Q, WESTHOF E 2003 Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide. J Mol Biol 326: 1175-1188
-
(2003)
J Mol Biol
, vol.326
, pp. 1175-1188
-
-
Vicens, Q.1
Westhof, E.2
-
55
-
-
0031965013
-
In vitro selection and characterization of streptomycin-binding RNAs: Recognition discrimination between antibiotics
-
WALLACE S T, SCHROEDER R 1998 In vitro selection and characterization of streptomycin-binding RNAs: recognition discrimination between antibiotics. RNA 4: 112-123
-
(1998)
RNA
, vol.4
, pp. 112-123
-
-
Wallace, S.T.1
Schroeder, R.2
-
56
-
-
0034255243
-
RNA aptamers that specifically bind to a 16S ribosomal RNA decoding region construct
-
TOKI J B, CHO J, RANDO R R 2000 RNA aptamers that specifically bind to a 16S ribosomal RNA decoding region construct. Nucleic Acids Res 28: 2902-2910
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 2902-2910
-
-
Toki, J.B.1
Cho, J.2
Rando, R.R.3
-
57
-
-
0034602848
-
Modulation of RNA function by aminoglycoside antibiotics
-
SCHROEDER R, WALDSICH C, WANK H 2000 Modulation of RNA function by aminoglycoside antibiotics. EMBO J 19: 1-9
-
(2000)
EMBO J
, vol.19
, pp. 1-9
-
-
Schroeder, R.1
Waldsich, C.2
Wank, H.3
-
58
-
-
0033548073
-
Effect of mutations in the A site of 16 S rRNA on aminoglycoside antibiotic-ribosome interaction
-
RECHT M I, DOUTHWAITE S, DAHLQUIST K D, PUGLISI J D 1999 Effect of mutations in the A site of 16 S rRNA on aminoglycoside antibiotic-ribosome interaction. J Mol Biol 286: 33-43
-
(1999)
J Mol Biol
, vol.286
, pp. 33-43
-
-
Recht, M.I.1
Douthwaite, S.2
Dahlquist, K.D.3
Puglisi, J.D.4
-
59
-
-
0023091436
-
Sites of action of two ribosomal RNA methylases responsible for resistance to aminoglycosides
-
BEAUCLERK A A, CUNDLIFFE E 1987 Sites of action of two ribosomal RNA methylases responsible for resistance to aminoglycosides. J Mol Biol 193: 661-671
-
(1987)
J Mol Biol
, vol.193
, pp. 661-671
-
-
Beauclerk, A.A.1
Cundliffe, E.2
-
60
-
-
0022344252
-
Methylation of 16S ribosomal RNA and resistance to the aminoglycoside antibiotics gentamicin and kanamycin determined by DNA from the gentamicin-producer, Micromonospora purpurea
-
THOMPSON J, SKEGGS P A, CUNDLIFFE E 1985 Methylation of 16S ribosomal RNA and resistance to the aminoglycoside antibiotics gentamicin and kanamycin determined by DNA from the gentamicin-producer, Micromonospora purpurea. Mol Gen Genet 201: 168-173
-
(1985)
Mol Gen Genet
, vol.201
, pp. 168-173
-
-
Thompson, J.1
Skeggs, P.A.2
Cundliffe, E.3
-
61
-
-
0042268055
-
Plasmid-mediated high-level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation
-
GALIMAND M, COURVALIN P, LAMBERT T 2003 Plasmid-mediated high-level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation. Antimicrob Agents Chemother 47: 2565-2571
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 2565-2571
-
-
Galimand, M.1
Courvalin, P.2
Lambert, T.3
-
62
-
-
0344687292
-
Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa
-
YOKOYAMA K, DOI Y, YAMANE K, KUROKAWA H, SHIBATA N, SHIBAYAMA K, YAGI T, KATO H, ARAKAWA Y 2003 Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa. Lancet 362: 1888-1893
-
(2003)
Lancet
, vol.362
, pp. 1888-1893
-
-
Yokoyama, K.1
Doi, Y.2
Yamane, K.3
Kurokawa, H.4
Shibata, N.5
Shibayama, K.6
Yagi, T.7
Kato, H.8
Arakawa, Y.9
-
63
-
-
0026031443
-
Cloning and characterization of gentamicin-resistance genes from Micromonospora purpurea and Micromonospora rosea
-
KELEMEN G H, CUNDLIFFE E, FINANCSEKI 1991 Cloning and characterization of gentamicin-resistance genes from Micromonospora purpurea and Micromonospora rosea. Gene 98: 53-60
-
(1991)
Gene
, vol.98
, pp. 53-60
-
-
Kelemen, G.H.1
Cundliffe, E.2
Financseki3
-
64
-
-
0027324801
-
Analysis of the self-defense gene (fmrO) of a fortimicin A (astromicin) producer, Micromonospora olivasterospora: Comparison with other aminoglycoside-resistance-encoding genes
-
OHTA T, HASEGAWA M 1993 Analysis of the self-defense gene (fmrO) of a fortimicin A (astromicin) producer, Micromonospora olivasterospora: comparison with other aminoglycoside-resistance-encoding genes. Gene 127: 63-69
-
(1993)
Gene
, vol.127
, pp. 63-69
-
-
Ohta, T.1
Hasegawa, M.2
-
65
-
-
0026471641
-
Cloning and characterization of an aminoglycoside resistance determinant from Micromonospora zionensis
-
KOJIC M, TOPISIROVIC L, VASILJEVIC B 1992 Cloning and characterization of an aminoglycoside resistance determinant from Micromonospora zionensis. J Bacteriol 174: 7868-7872
-
(1992)
J Bacteriol
, vol.174
, pp. 7868-7872
-
-
Kojic, M.1
Topisirovic, L.2
Vasiljevic, B.3
-
66
-
-
0028867394
-
Construction of thiostrepton-inducible, high-copy-number expression vectors for use in Streptomyces spp
-
TAKANO E, WHITE J, THOMPSON C J, BIBB M J 1995 Construction of thiostrepton-inducible, high-copy-number expression vectors for use in Streptomyces spp. Gene 166: 133-137
-
(1995)
Gene
, vol.166
, pp. 133-137
-
-
Takano, E.1
White, J.2
Thompson, C.J.3
Bibb, M.J.4
-
67
-
-
0031705699
-
Analysis of a kanamycin resistance gene (kmr) from Streptomyces kanamyceticus and a mutant with increased aminoglycoside resistance
-
DEMYDCHUK J, OLIYNYK Z, FEDORENKO V 1998 Analysis of a kanamycin resistance gene (kmr) from Streptomyces kanamyceticus and a mutant with increased aminoglycoside resistance. J Basic Microbiol 38: 231-239
-
(1998)
J Basic Microbiol
, vol.38
, pp. 231-239
-
-
Demydchuk, J.1
Oliynyk, Z.2
Fedorenko, V.3
-
68
-
-
0023278592
-
Cloning of aminoglycoside-resistance determinants from Streptomyces tenebrarius and comparison with related genes from other actinomycetes
-
SKEGGS P A, HOLMES D J, CUNDLIFFE E 1987 Cloning of aminoglycoside- resistance determinants from Streptomyces tenebrarius and comparison with related genes from other actinomycetes. J Gen Microbiol 133: 915-923
-
(1987)
J Gen Microbiol
, vol.133
, pp. 915-923
-
-
Skeggs, P.A.1
Holmes, D.J.2
Cundliffe, E.3
-
69
-
-
0942279627
-
Plasmid-mediated 16S rRNA methylase in Serratia marcescens conferring high-level resistance to aminoglycosides
-
DOI Y, YOKOYAMA K, YAMANE K, WACHINO J, SHIBATA N, YAGI T, SHIBAYAMA K, KATO H, ARAKAWA Y 2004 Plasmid-mediated 16S rRNA methylase in Serratia marcescens conferring high-level resistance to aminoglycosides. Antimicrob Agents Chemother 48: 491-496
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 491-496
-
-
Doi, Y.1
Yokoyama, K.2
Yamane, K.3
Wachino, J.4
Shibata, N.5
Yagi, T.6
Shibayama, K.7
Kato, H.8
Arakawa, Y.9
-
70
-
-
0029833935
-
Translational autoregulation of the sgm gene from Micromonospora zionensis
-
KOJIC M, TOPISIROVIC L, VASILIEVIC B 1996 Translational autoregulation of the sgm gene from Micromonospora zionensis. J Bacteriol 178: 5493-5498
-
(1996)
J Bacteriol
, vol.178
, pp. 5493-5498
-
-
Kojic, M.1
Topisirovic, L.2
Vasilievic, B.3
-
71
-
-
0034977748
-
Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases
-
BUJNICKI J M, RYCHLEWSKI L 2001 Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases. Acta Microbiol Pol 50: 7-17
-
(2001)
Acta Microbiol Pol
, vol.50
, pp. 7-17
-
-
Bujnicki, J.M.1
Rychlewski, L.2
-
72
-
-
0028846665
-
Assays to detect and characterize synthetic agents that inhibit the ErmC methyltransferase
-
CLANCY J, SCHMIEDER B J, PETITPAS J W, MANOUSOS M, WILLIAMS J A, FAIELLA J A, GIRARD A E, MCGUIRK P R Assays to detect and characterize synthetic agents that inhibit the ErmC methyltransferase. J Antibiot (Tokyo) (1995) 48: 1273-1279
-
(1995)
J Antibiot (Tokyo)
, vol.48
, pp. 1273-1279
-
-
Clancy, J.1
Schmieder, B.J.2
Petitpas, J.W.3
Manousos, M.4
Williams, J.A.5
Faiella, J.A.6
Girard, A.E.7
Mcguirk, P.R.8
-
73
-
-
0033598415
-
Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis
-
HAJDUK P J, DINGES J, SCHKERYANTZ J M, JANOWICK D, KAMINSKI M, TUFANO M, AUGERI D J, PETROS A, NIENABER V, ZHONG P, HAMMOND R, COEN M, BEUTEL B, KATZ L, FESIK S W 1999 Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis. J Med Chem 42: 3852-3859
-
(1999)
J Med Chem
, vol.42
, pp. 3852-3859
-
-
Hajduk, P.J.1
Dinges, J.2
Schkeryantz, J.M.3
Janowick, D.4
Kaminski, M.5
Tufano, M.6
Augeri, D.J.7
Petros, A.8
Nienaber, V.9
Zhong, P.10
Hammond, R.11
Coen, M.12
Beutel, B.13
Katz, L.14
Fesik, S.W.15
-
74
-
-
0029926820
-
S-Adenosylmethionine and methylation
-
CHIANG P K, GORDON R K, TAL J, ZENG G C, DOCTOR B P, PARDHASARADHI K, MCCANN P P 1996 S-Adenosylmethionine and methylation. FASEB J 10: 471-480
-
(1996)
FASEB J
, vol.10
, pp. 471-480
-
-
Chiang, P.K.1
Gordon, R.K.2
Tal, J.3
Zeng, G.C.4
Doctor, B.P.5
Pardhasaradhi, K.6
Mccann, P.P.7
|