Macrolide antibiotic interaction and resistance on the bacterial ribosome

Current Opinion in Investigational Drugs

Volumn 4, Issue 2, 2003, Pages 140-148

  Poehlsgaard, Jacob ^a   Douthwaite, Stephen ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Macrolide resistance; MLSB antibiotics; Ribosome crystal structures; rRNA methylation

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL PROTEIN; CARBOMYCIN; CLINDAMYCIN; ERYTHROMYCIN; LINCOMYCIN; LINCOSAMIDE; MACROLIDE; MIKAMYCIN B; MYCINAMICIN; RIBOSOME RNA; SPIRAMYCIN; TELITHROMYCIN; TYLOSIN;

AMINO ACID SUBSTITUTION; ANTIBIOTIC BIOSYNTHESIS; ANTIBIOTIC RESISTANCE; BIOCHEMISTRY; CELL STRUCTURE; CRYSTAL STRUCTURE; DEINOCOCCUS RADIODURANS; DRUG BINDING SITE; DRUG DESIGN; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; GENE MUTATION; HALOARCULA; HUMAN; MOLECULAR MECHANICS; NONHUMAN; PROTEIN SYNTHESIS INHIBITION; REVIEW; RIBOSOME; RNA METHYLATION; X RAY CRYSTALLOGRAPHY;

ANTI-BACTERIAL AGENTS; BACTERIA; DRUG RESISTANCE, BACTERIAL; MACROLIDES; METHYLATION; MODELS, MOLECULAR; MUTATION; RIBOSOMES; RNA, RIBOSOMAL, 23S;

EID: 0037303518     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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