Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice

Journal of Clinical Investigation

Volumn 114, Issue 4, 2004, Pages 582-588

  Hata, Hiroshi ^a,b   Sakaguchi, Noriko ^a,c   Yoshitomi, Hiroyuki ^a,b   Iwakura, Yoichiroh ^d   Sekikawa, Kenji ^e   Azuma, Yoshiaki ^f   Kanai, Chieko ^g   Moriizumi, Eiko ^g   Nomura, Takashi ^a   Nakamura, Takashi ^b   Sakaguchi, Shimon ^a,c,h  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c RIKEN   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^f TEIJIN PHARMA LIMITED   (Japan)

^g TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^h JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6; RHEUMATOID FACTOR; TUMOR NECROSIS FACTOR ALPHA; AUTOANTIBODY; MESSENGER RNA; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CELL FUNCTION; CELL POPULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE ACTIVITY; DISEASE COURSE; DISEASE EXACERBATION; DISEASE MODEL; DISEASE SEVERITY; FEMALE; GENETIC TRANSCRIPTION; IMMUNOHISTOCHEMISTRY; INCIDENCE; JOINT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; QUANTITATIVE ANALYSIS; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; SYNOVIOCYTE; SYNOVITIS; T LYMPHOCYTE; TH1 CELL; TH2 CELL; ANIMAL; ARTHRITIS; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CELL DIVISION; COMPARATIVE STUDY; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; GENETICS; HETEROZYGOTE; HOMOZYGOTE; IMMUNOLOGY; MACROPHAGE; METABOLISM; MOUSE MUTANT; MOUSE STRAIN; PATHOLOGY; ULTRASTRUCTURE;

ANIMALS; ARTHRITIS, EXPERIMENTAL; AUTOANTIBODIES; CD4-POSITIVE T-LYMPHOCYTES; CELL DIVISION; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; HETEROZYGOTE; HOMOZYGOTE; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; INTERLEUKIN-10; INTERLEUKIN-6; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED STRAINS; MICE, KNOCKOUT; PROTEINS; RNA, MESSENGER; SYNOVIAL FLUID; SYNOVITIS; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4344590199     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200421795     Document Type: Article

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