-
1
-
-
0034727717
-
Primary pulmonary hypertension: A vascular biology and translational research 'Work in progress'
-
Archer, S. and Rich, S. (2000). Primary pulmonary hypertension: a vascular biology and translational research 'Work in progress'. Circulation 102, 2781-2791.
-
(2000)
Circulation
, vol.102
, pp. 2781-2791
-
-
Archer, S.1
Rich, S.2
-
2
-
-
0034682786
-
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1 during hypoxia
-
Chandel, N.S., McClintock, D.S., Feliciano, C.E., Teresa, M., Wood, J., Melendez, A., Rodriguez A.M., and Schumacker, P.T. (2000). Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1 during hypoxia. J. Biol. Chem. 275, 25130-25138.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25130-25138
-
-
Chandel, N.S.1
McClintock, D.S.2
Feliciano, C.E.3
Teresa, M.4
Wood, J.5
Melendez, A.6
Rodriguez, A.M.7
Schumacker, P.T.8
-
3
-
-
0032090254
-
Increased vascular endothelial growth factor production in the lungs of rats with hypoxia-induced pulmonary hypertension
-
Christou, H., Yoshida,, A., Arthur, V., Morita, T., and Kourembanas, S. (1998). Increased vascular endothelial growth factor production in the lungs of rats with hypoxia-induced pulmonary hypertension. Am. J. Respir. Cell. Mol. Biol. 18, 768-776.
-
(1998)
Am. J. Respir. Cell. Mol. Biol.
, vol.18
, pp. 768-776
-
-
Christou, H.1
Yoshida, A.2
Arthur, V.3
Morita, T.4
Kourembanas, S.5
-
4
-
-
0035930627
-
Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1α protein by the oxidative stressor arsenite
-
Duyndam, M.C., Hulscher, T.M., Fontijn, D., Pinedo, H.M., and Boven, E. (2001). Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1α protein by the oxidative stressor arsenite. J. Biol. Chem. 276, 48066-48076.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48066-48076
-
-
Duyndam, M.C.1
Hulscher, T.M.2
Fontijn, D.3
Pinedo, H.M.4
Boven, E.5
-
5
-
-
0027970536
-
Role of hydrogen peroxide in hypoxia-induced erythropoietin production
-
Fandrey, J., Frede, S., and Jelkmann, W. (1994). Role of hydrogen peroxide in hypoxia-induced erythropoietin production. Biochem. J. 303, 507-510.
-
(1994)
Biochem. J.
, vol.303
, pp. 507-510
-
-
Fandrey, J.1
Frede, S.2
Jelkmann, W.3
-
6
-
-
0037160034
-
p38 signaling-mediated hypoxia-inducible factor 1α and vascular endothelial growth factor induction by Cr(VI) in DU145 human prostate carcinoma cells
-
Gao, N., Jiang, B.H., Leonard, S.S., Corum, L., Zhang, Z., Roberts, J.R., Antonini, J., Zheng, J.Z., Flynn, D.C., Castranova, V., and Shi, X. (2002). p38 signaling-mediated hypoxia-inducible factor 1α and vascular endothelial growth factor induction by Cr(VI) in DU145 human prostate carcinoma cells. J. Biol. Chem. 277, 45041-45048.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45041-45048
-
-
Gao, N.1
Jiang, B.H.2
Leonard, S.S.3
Corum, L.4
Zhang, Z.5
Roberts, J.R.6
Antonini, J.7
Zheng, J.Z.8
Flynn, D.C.9
Castranova, V.10
Shi, X.11
-
7
-
-
0034039949
-
Enhanced expression of vascular endothelial growth factor in pulmonary plexogenic arteriopathy due to congenital heart disease
-
Geiger, R., Berger, R.M., Hess, J., Bogers, A.J., Sharma, H.S., and Mooi, W.J. (2000). Enhanced expression of vascular endothelial growth factor in pulmonary plexogenic arteriopathy due to congenital heart disease. J. Pathol. 191, 202-207.
-
(2000)
J. Pathol.
, vol.191
, pp. 202-207
-
-
Geiger, R.1
Berger, R.M.2
Hess, J.3
Bogers, A.J.4
Sharma, H.S.5
Mooi, W.J.6
-
8
-
-
2342667629
-
Primary pulmonary hypertension: An overview of epidemiology and pathogenesis
-
Ghamra, Z.W., and Dweik, RA. (2003). Primary pulmonary hypertension: an overview of epidemiology and pathogenesis. Cleve. Clin. J. Med. 70, S2-8.
-
(2003)
Cleve. Clin. J. Med.
, vol.70
-
-
Ghamra, Z.W.1
Dweik, R.A.2
-
9
-
-
0035816732
-
Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase
-
Görlach, A., Diebold, I., Schini-Kerth, V.B., Berchner-Pfannschmidt, U., Roth, U., Brandes, R.P., Kietzmann, T., and Busse, R. (2001). Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: role of the p22(phox)-containing NADPH oxidase. Circ. Res. 89, 47-54.
-
(2001)
Circ. Res.
, vol.89
, pp. 47-54
-
-
Görlach, A.1
Diebold, I.2
Schini-Kerth, V.B.3
Berchner-Pfannschmidt, U.4
Roth, U.5
Brandes, R.P.6
Kietzmann, T.7
Busse, R.8
-
10
-
-
0037954222
-
Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: Involvement of the GTPase Rac1
-
Görlach, A., Berchner-Pfannschmidt, U., Wotzlaw, C., Cool, R.H., Fandrey, J., Acker, H., Jungermann, K., and Kietzmann, T. (2003). Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1. Thromb. Haemost. 89, 926-935.
-
(2003)
Thromb. Haemost.
, vol.89
, pp. 926-935
-
-
Görlach, A.1
Berchner-Pfannschmidt, U.2
Wotzlaw, C.3
Cool, R.H.4
Fandrey, J.5
Acker, H.6
Jungermann, K.7
Kietzmann, T.8
-
11
-
-
0033181324
-
Interleukin-1β and tumor necrosis factor-α stimulate DNA binding of hypoxia-inducible factor-1
-
Hellwig-Burgel, T., Rutkowski, K., Metzen, E., Fandrey, J., Jelkmann, W. (1999). Interleukin-1β and tumor necrosis factor-α stimulate DNA binding of hypoxia-inducible factor-1. Blood 94, 1561-1567.
-
(1999)
Blood
, vol.94
, pp. 1561-1567
-
-
Hellwig-Burgel, T.1
Rutkowski, K.2
Metzen, E.3
Fandrey, J.4
Jelkmann, W.5
-
12
-
-
0034803631
-
Pathobiology of pulmonary hypertension. The role of platelets and thrombosis
-
Herve, P., Humbert, M., Sitbon, O., Parent, F., Nunes., H., Legal, C., Garcia, G., and Simonneau, G. (2001). Pathobiology of pulmonary hypertension. The role of platelets and thrombosis. Clin. Chest. Med. 22, 451-458.
-
(2001)
Clin. Chest Med.
, vol.22
, pp. 451-458
-
-
Herve, P.1
Humbert, M.2
Sitbon, O.3
Parent, F.4
Nunes, H.5
Legal, C.6
Garcia, G.7
Simonneau, G.8
-
13
-
-
0035877728
-
Rac1 activity is required for the activation of hypoxia-inducible factor 1
-
Hirota, K., and Semenza, G.L. (2001). Rac1 activity is required for the activation of hypoxia-inducible factor 1. J. Biol. Chem. 276, 21166-21172.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21166-21172
-
-
Hirota, K.1
Semenza, G.L.2
-
14
-
-
0029753008
-
Act2ivation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
-
Huang, L.E., Arany, Z., Livingston, D.M., and Bunn, H.F. (1996). Act2ivation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J. Biol. Chem. 271, 32253-32259.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
15
-
-
0036624857
-
Oxidative stress in patients with primary pulmonary hypertension
-
Irodova, N.L., Lankin, V.Z., Konovalova, G.K., Kochetov, A.G., and Chazova, I.E. (2002). Oxidative stress in patients with primary pulmonary hypertension. Bull. Exp. Biol. Med. 133, 580-582.
-
(2002)
Bull. Exp. Biol. Med.
, vol.133
, pp. 580-582
-
-
Irodova, N.L.1
Lankin, V.Z.2
Konovalova, G.K.3
Kochetov, A.G.4
Chazova, I.E.5
-
16
-
-
0032889677
-
Redox regulation of cellular signalling
-
Kamata, H., and Hirata, H. (1999). Redox regulation of cellular signalling. Cell Signal. 11, 1-14.
-
(1999)
Cell Signal.
, vol.11
, pp. 1-14
-
-
Kamata, H.1
Hirata, H.2
-
17
-
-
0035868277
-
Perivenous expression of the mRNA of the three hypoxia-inducible factor α-subunits, HIF1α, HIF2α and HIF3α, in rat liver
-
Kietzmann, T., Cornesse, Y., Brechtel, K., Modaressi, S., and Jungermann, K. (2001). Perivenous expression of the mRNA of the three hypoxia-inducible factor α-subunits, HIF1α, HIF2α and HIF3α, in rat liver. Biochem. J. 354, 531-537.
-
(2001)
Biochem. J.
, vol.354
, pp. 531-537
-
-
Kietzmann, T.1
Cornesse, Y.2
Brechtel, K.3
Modaressi, S.4
Jungermann, K.5
-
19
-
-
0036058185
-
Stabilization of hypoxia-inducible factor-1alpha is involved in the hypoxic stimuli-induced expression of vascular endothelial growth factor in osteoblastic cells
-
Kim, H.H., Lee, S.E., Chung, W.J., Choi, Y., Kwack, K., Kim, S.W., Kim, M.S., Park, H., and Lee, Z.H. (2002). Stabilization of hypoxia-inducible factor-1alpha is involved in the hypoxic stimuli-induced expression of vascular endothelial growth factor in osteoblastic cells. Cytokine 17, 14-27.
-
(2002)
Cytokine
, vol.17
, pp. 14-27
-
-
Kim, H.H.1
Lee, S.E.2
Chung, W.J.3
Choi, Y.4
Kwack, K.5
Kim, S.W.6
Kim, M.S.7
Park, H.8
Lee, Z.H.9
-
20
-
-
0037446983
-
Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells
-
Knowles, H.J., Raval, R.R., Harris, A.L., and Ratcliffe, P.J. (2003). Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells. Cancer Res. 63, 1764-1768.
-
(2003)
Cancer Res.
, vol.63
, pp. 1764-1768
-
-
Knowles, H.J.1
Raval, R.R.2
Harris, A.L.3
Ratcliffe, P.J.4
-
21
-
-
0031600968
-
2 sensors in hypoxic regulation of tyrosine hydroxylase gene expression
-
2 sensors in hypoxic regulation of tyrosine hydroxylase gene expression. Am. J. Physiol. 274, C167-74.
-
(1998)
Am. J. Physiol.
, vol.274
-
-
Kroll, S.L.1
Czyzyk-Krzeska, M.F.2
-
22
-
-
0037974675
-
Expression of VEGF and its receptors Flt-1 and Flk-1/KDR is altered in lambs with increased pulmonary blood flow and pulmonary hypertension
-
Mata-Greenwood, E., Meyrick, B., Soifer, S.J., Fineman, J.R., and Black, S.M. (2003). Expression of VEGF and its receptors Flt-1 and Flk-1/KDR is altered in lambs with increased pulmonary blood flow and pulmonary hypertension. Am. J. Physiol. Lung Cell. Mol. Physiol. 285, L222-231.
-
(2003)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.285
-
-
Mata-Greenwood, E.1
Meyrick, B.2
Soifer, S.J.3
Fineman, J.R.4
Black, S.M.5
-
23
-
-
0036830469
-
Regulation of gene expression by oxygen: NF-κB and HIF-1, two extremes
-
Michiels, C., Minet, E., Mottet, D., and Raes, M. (2002). Regulation of gene expression by oxygen: NF-κB and HIF-1, two extremes. Free Radic. Biol. Med. 33, 1231-1242.
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 1231-1242
-
-
Michiels, C.1
Minet, E.2
Mottet, D.3
Raes, M.4
-
24
-
-
0036846220
-
Detection of superoxide in vascular tissue
-
Munzel, T., Afanas'ev, I.B., Kleschyov, A.L., and Harrison, D.G. (2002). Detection of superoxide in vascular tissue. Arterioscler. Thromb. Vasc. Biol. 22, 1761-1768.
-
(2002)
Arterioscler Thromb. Vasc. Biol.
, vol.22
, pp. 1761-1768
-
-
Munzel, T.1
Afanas'ev, I.B.2
Kleschyov, A.L.3
Harrison, D.G.4
-
25
-
-
0030660501
-
Multiple redox regulation in NF-κB transcription factor activation
-
Piette, J., Piret, B., Bonizzi G., Schoonbroodt, S., Merville, M.P., Legrand-Poels, S., and Bours, V. (1997). Multiple redox regulation in NF-κB transcription factor activation. Biol. Chem. 378, 1237-1245.
-
(1997)
Biol. Chem.
, vol.378
, pp. 1237-1245
-
-
Piette, J.1
Piret, B.2
Bonizzi, G.3
Schoonbroodt, S.4
Merville, M.P.5
Legrand-Poels, S.6
Bours, V.7
-
26
-
-
0034282388
-
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1α in vascular smooth muscle cells
-
Richard, D.E., Berra, E., and Pouyssegur, J. (2000). Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1α in vascular smooth muscle cells. J. Biol. Chem. 275, 26765-26771.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26765-26771
-
-
Richard, D.E.1
Berra, E.2
Pouyssegur, J.3
-
27
-
-
0037362890
-
HIF hydroxylation and the mammalian oxygen-sensing pathway
-
Safran, M., and Kaelin Jr., W.G. (2003). HIF hydroxylation and the mammalian oxygen-sensing pathway. J. Clin. Invest. 111, 779-783.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 779-783
-
-
Safran, M.1
Kaelin Jr., W.G.2
-
29
-
-
0034901463
-
Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
-
Semenza, G. L. (2001). Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Trends. Mol. Med. 7, 345-350
-
(2001)
Trends. Mol. Med.
, vol.7
, pp. 345-350
-
-
Semenza, G.L.1
-
30
-
-
0038115172
-
Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1α (HIF-1α) accumulation via redox-dependent mechanisms
-
Shatrov, V.A., Sumbayev, V.V., Zhou, J., and Brune, B. (2003). Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1α (HIF-1α) accumulation via redox-dependent mechanisms. Blood 101, 4847-4849.
-
(2003)
Blood
, vol.101
, pp. 4847-4849
-
-
Shatrov, V.A.1
Sumbayev, V.V.2
Zhou, J.3
Brune, B.4
-
31
-
-
0034772039
-
Expression of angiogenesis-related molecules in plexiform lesions in severe pulmonary hypertension: Evidence for a process of disordered angiogenesis
-
Tuder, R.M., Chacon, M., Alger, L., Wang, J., Taraseviciene-Stewart, L., Kasahara, Y., Cool, C.D., Bishop, A.E., Geraci, M., Semenza, G.L. et al. (2001). Expression of angiogenesis-related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis. J. Pathol. 195, 367-374.
-
(2001)
J. Pathol.
, vol.195
, pp. 367-374
-
-
Tuder, R.M.1
Chacon, M.2
Alger, L.3
Wang, J.4
Taraseviciene-Stewart, L.5
Kasahara, Y.6
Cool, C.D.7
Bishop, A.E.8
Geraci, M.9
Semenza, G.L.10
-
32
-
-
0029123437
-
Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1
-
Wang, G.L., Jiang, B.H., and Semenza, G.L. (1995). Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1. Biochem. Biophys. Res. Commun. 212, 550-556.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.212
, pp. 550-556
-
-
Wang, G.L.1
Jiang, B.H.2
Semenza, G.L.3
-
33
-
-
0036320934
-
2-regulated gene expression
-
2-regulated gene expression. FASEB J. 16, 1151-1162.
-
(2002)
FASEB J.
, vol.16
, pp. 1151-1162
-
-
Wenger, R.H.1
-
34
-
-
0032189844
-
Induction of endothelial PAS domain protein-1 by hypoxia: Characterization and comparison with hypoxia-inducible factor-1α
-
Wiesener, M.S., Turley, H., Allen, W.E., Willam, C., Eckardt, K.U., Talks, K.L., Wood, S.M., Gatter, K.C., Harris, A.L., Pugh, C.W. et al. (1998). Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1α. Blood 92, 2260-2268.
-
(1998)
Blood
, vol.92
, pp. 2260-2268
-
-
Wiesener, M.S.1
Turley, H.2
Allen, W.E.3
Willam, C.4
Eckardt, K.U.5
Talks, K.L.6
Wood, S.M.7
Gatter, K.C.8
Harris, A.L.9
Pugh, C.W.10
-
35
-
-
0037947590
-
Redox regulation of HIF-1α levels and HO-1 expression in renal medullary interstitial cells
-
Yang, Z.Z., Zhang, A.Y., Yi, F.X., Li, P.L., and Zou, A.P. (2003). Redox regulation of HIF-1α levels and HO-1 expression in renal medullary interstitial cells. Am. J. Physiol. Renal Physiol. 284, F1207-1215.
-
(2003)
Am. J. Physiol. Renal. Physiol.
, vol.284
-
-
Yang, Z.Z.1
Zhang, A.Y.2
Yi, F.X.3
Li, P.L.4
Zou, A.P.5
-
36
-
-
0032169214
-
Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1α/ARNT
-
Zelzer, E., Levy, Y., Kahana, C., Shilo, B.Z., Rubinstein, M., and Cohen, B. (1998). Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1α/ARNT. EMBO J. 17, 5085-5094.
-
(1998)
EMBO J.
, vol.17
, pp. 5085-5094
-
-
Zelzer, E.1
Levy, Y.2
Kahana, C.3
Shilo, B.Z.4
Rubinstein, M.5
Cohen, B.6
|