-
1
-
-
0015462030
-
Combination cancer therapy: Presidential address
-
Frei E. Combination cancer therapy: Presidential address. Cancer Res. 32:1972;2593-2607.
-
(1972)
Cancer Res.
, vol.32
, pp. 2593-2607
-
-
Frei, E.1
-
2
-
-
0016756272
-
Continuous culture of fused cells secreting antibody of predefined specificity
-
Kohler G., Milstein C. Continuous culture of fused cells secreting antibody of predefined specificity. Nature. 256:1975;495-497.
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
3
-
-
0342832999
-
Improved oral drug delivery: Solubility limitations overcome by the use of prodrugs
-
Fleisher D., Bong R., Stewart B.H. Improved oral drug delivery: solubility limitations overcome by the use of prodrugs. Adv. Drug Deliv. Rev. 19:1996;115-130.
-
(1996)
Adv. Drug Deliv. Rev.
, vol.19
, pp. 115-130
-
-
Fleisher, D.1
Bong, R.2
Stewart, B.H.3
-
4
-
-
0343462226
-
Prodrugs and targeted drug delivery
-
Kearney A.S. Prodrugs and targeted drug delivery. Adv. Drug Deliv. Rev. 19:1996;225-239.
-
(1996)
Adv. Drug Deliv. Rev.
, vol.19
, pp. 225-239
-
-
Kearney, A.S.1
-
6
-
-
0010558895
-
Tumor cell biology: Tumor specific and associated antigens
-
in: M.R. Zalutsky (Ed.) CRC, Boca Raton, FL
-
A.M. Carroll, M.I. Greene, Tumor cell biology: tumor specific and associated antigens, in: M.R. Zalutsky (Ed.), Antibodies in Radiodiagnosis and Therapy. CRC, Boca Raton, FL, 1989, pp. 13-43.
-
(1989)
Antibodies in Radiodiagnosis and Therapy
, pp. 13-43
-
-
Carroll, A.M.1
Greene, M.I.2
-
7
-
-
0021269010
-
Strategies for production of monoclonal anti-idiotype antibodies against B-cell lymphomas
-
Thielemans K., Maloney D.G., Meeker T., Fujimoto J., Doss C., Warnke R.A., Bind J., Gralow K., Miller R.A., Levy R. Strategies for production of monoclonal anti-idiotype antibodies against B-cell lymphomas. J. Immunol. 133:1984;495-501.
-
(1984)
J. Immunol.
, vol.133
, pp. 495-501
-
-
Thielemans, K.1
Maloney, D.G.2
Meeker, T.3
Fujimoto, J.4
Doss, C.5
Warnke, R.A.6
Bind, J.7
Gralow, K.8
Miller, R.A.9
Levy, R.10
-
8
-
-
0029991439
-
HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastaic breast cancer
-
HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastaic breast cancer. J. Clin. Oncol. 14:1996;737-744.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
Baughman, S.4
Benz, C.C.5
Dantis, L.6
Sklarin, N.T.7
Seidman, A.D.8
Hudis, C.A.9
Moore, J.10
Rosen, P.P.11
Twadell, T.12
Henderson, I.C.13
Norton, L.14
-
9
-
-
0028049374
-
Humanization of murine monoclonal antibodies through variable domain resurfacing
-
Roguska M.A., Pedersen J.T., Keddy C.A., Henry A.H., Searle S.J., Lambert J.M., Goldmacher V.S., Blättler W.A., Rees A.R., Guild B.C. Humanization of murine monoclonal antibodies through variable domain resurfacing. Proc. Natl. Acad. Sci. USA. 91:1994;969-973.
-
(1994)
Proc. Natl. Acad. Sci. USA.
, vol.91
, pp. 969-973
-
-
Roguska, M.A.1
Pedersen, J.T.2
Keddy, C.A.3
Henry, A.H.4
Searle, S.J.5
Lambert, J.M.6
Goldmacher, V.S.7
Blättler, W.A.8
Rees, A.R.9
Guild, B.C.10
-
10
-
-
10344237543
-
A comparison of two murine monoclonal antibodies humanized by CDR-grafting and variable domain resurfacing
-
Roguska M.A., Pedersen J.T., Henry A.H., Searle S.M.J., Roja C.M., Avery B., Hoffee M., Cook S., Lambert J.M., Blattler W.A., Rees A.R., Guild G.C. A comparison of two murine monoclonal antibodies humanized by CDR-grafting and variable domain resurfacing. Protein Eng. 9:1996;895-904.
-
(1996)
Protein Eng.
, vol.9
, pp. 895-904
-
-
Roguska, M.A.1
Pedersen, J.T.2
Henry, A.H.3
Searle, S.M.J.4
Roja, C.M.5
Avery, B.6
Hoffee, M.7
Cook, S.8
Lambert, J.M.9
Blattler, W.A.10
Rees, A.R.11
Guild, G.C.12
-
11
-
-
0026684815
-
Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms
-
Yokota T., Milenic D.E., Whitlow M., Schlom J. Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res. 52:1992;3402-3408.
-
(1992)
Cancer Res.
, vol.52
, pp. 3402-3408
-
-
Yokota, T.1
Milenic, D.E.2
Whitlow, M.3
Schlom, J.4
-
12
-
-
0027249714
-
Microautoradiographic analysis of the normal organ distribution of radioiodinated single-chain Fv and other immunoglobulin forms
-
Yokota T., Milenic D.E., Whitlow M., Wood J.F., Hubert S.L., Schlom J. Microautoradiographic analysis of the normal organ distribution of radioiodinated single-chain Fv and other immunoglobulin forms. Cancer Res. 53:1993;3776-3783.
-
(1993)
Cancer Res.
, vol.53
, pp. 3776-3783
-
-
Yokota, T.1
Milenic, D.E.2
Whitlow, M.3
Wood, J.F.4
Hubert, S.L.5
Schlom, J.6
-
13
-
-
0028091566
-
Improved tumor targeting with chemically cross-linked recombinant antibody fragments
-
King D.J., Turner A., Farnsworth A.P.H., Adair J.R., Owens R.J., Pedley R.B., Baldock D., Proudfoot K.A., Lawson A.D.G., Beeley N.R.A., Millar K., Millican T.A., Boyce B.A., Antoniw P., Mountain A., Begent R.H.J., Shochat D., Yarranton Y.T. Improved tumor targeting with chemically cross-linked recombinant antibody fragments. Cancer Res. 54:1994;6176-6185.
-
(1994)
Cancer Res.
, vol.54
, pp. 6176-6185
-
-
King, D.J.1
Turner, A.2
Farnsworth, A.P.H.3
Adair, J.R.4
Owens, R.J.5
Pedley, R.B.6
Baldock, D.7
Proudfoot, K.A.8
Lawson, A.D.G.9
Beeley, N.R.A.10
Millar, K.11
Millican, T.A.12
Boyce, B.A.13
Antoniw, P.14
Mountain, A.15
Begent, R.H.J.16
Shochat, D.17
Yarranton, Y.T.18
-
14
-
-
0001874124
-
Epidermal growth factor and its receptor in human cancer
-
in: M. Sluyser (Ed.) VCH, Chichester
-
A.L. Harris, D. Neal, Epidermal growth factor and its receptor in human cancer, in: M. Sluyser (Ed.), Growth Factors and Oncogenes in Breast Cancer. VCH, Chichester, 1987, pp. 60-90.
-
(1987)
Growth Factors and Oncogenes in Breast Cancer
, pp. 60-90
-
-
Harris, A.L.1
Neal, D.2
-
15
-
-
0024998005
-
The epidermal growth factor receptor as a target for therapy
-
Harris A.L. The epidermal growth factor receptor as a target for therapy. Cancer Cells. 2:1990;321-323.
-
(1990)
Cancer Cells
, vol.2
, pp. 321-323
-
-
Harris, A.L.1
-
17
-
-
0025647695
-
Transforming growth factor-α
-
Massague J. Transforming growth factor-α J. Biol. Chem. 265:1990;21393-21396.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 21393-21396
-
-
Massague, J.1
-
18
-
-
0017767854
-
Melanotropin-daunomycin conjugate shows receptor-mediated cytotoxicity in cultured murine melanoma cells
-
Varga J.M., Asato N., Lande S., Lerner A.B. Melanotropin-daunomycin conjugate shows receptor-mediated cytotoxicity in cultured murine melanoma cells. Nature. 267:1977;56-58.
-
(1977)
Nature
, vol.267
, pp. 56-58
-
-
Varga, J.M.1
Asato, N.2
Lande, S.3
Lerner, A.B.4
-
19
-
-
0021891363
-
Hormone-drug conjugates
-
Academic Press
-
J.M. Varga, Hormone-drug conjugates, in: Methods in Enzymology, Academic Press 112, 1985, pp. 259-269.
-
(1985)
in: Methods in Enzymology
, vol.112
, pp. 259-269
-
-
Varga, J.M.1
-
20
-
-
0028002716
-
Preparation and characterization of interleukin-2-gelonin conjugates made using different cross-linking reagents
-
McIntyre G.D., Scott C.F., Ritz J., Blättler W.A., Lambert J.M. Preparation and characterization of interleukin-2-gelonin conjugates made using different cross-linking reagents. Bioconjugate Chem. 5:1994;88-97.
-
(1994)
Bioconjugate Chem.
, vol.5
, pp. 88-97
-
-
McIntyre, G.D.1
Scott, C.F.2
Ritz, J.3
Blättler, W.A.4
Lambert, J.M.5
-
21
-
-
0023191378
-
Target-selective cytotoxicity of methotrexate conjugated with monoclonal anti-MM46 antibody
-
Endo N., Takeda Y., Kishida K., Kato Y., Saito M., Umemoto N., Hara T. Target-selective cytotoxicity of methotrexate conjugated with monoclonal anti-MM46 antibody. Cancer Immunol. Immunother. 25:1987;1-6.
-
(1987)
Cancer Immunol. Immunother.
, vol.25
, pp. 1-6
-
-
Endo, N.1
Takeda, Y.2
Kishida, K.3
Kato, Y.4
Saito, M.5
Umemoto, N.6
Hara, T.7
-
22
-
-
0023727121
-
Biodistribution and tumor localization of a daunomycin-monoclonal antibody conjugate in nude mice with human tumor xenografts
-
Pimm M.V., Paul M.A., Ogumuyiwa Y., Baldwin R.W. Biodistribution and tumor localization of a daunomycin-monoclonal antibody conjugate in nude mice with human tumor xenografts. Cancer Immunol. Immunother. 27:1988;267-271.
-
(1988)
Cancer Immunol. Immunother.
, vol.27
, pp. 267-271
-
-
Pimm, M.V.1
Paul, M.A.2
Ogumuyiwa, Y.3
Baldwin, R.W.4
-
23
-
-
0023248720
-
Disposition of the monoclonal antibody-Vinca alkaloid conjugate KS1/4-DAVLB (LY256787) and free 4-desacetylvinblastine (DAVLB) in tumor-bearing nude mice
-
Spearman M.E., Goodwin R.M., Apelgren L.D., Bumol T.F. Disposition of the monoclonal antibody-Vinca alkaloid conjugate KS1/4-DAVLB (LY256787) and free 4-desacetylvinblastine (DAVLB) in tumor-bearing nude mice. J. Pharmacol. Exp. Ther. 241:1987;695-703.
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.241
, pp. 695-703
-
-
Spearman, M.E.1
Goodwin, R.M.2
Apelgren, L.D.3
Bumol, T.F.4
-
24
-
-
0021043785
-
Enhanced anti-tumor activity of mitomycin C conjugated with anti-α-fetoprotein antibody by a novel method of conjugation
-
Kato Y., Tsukada Y., Hara T., Hirai H. Enhanced anti-tumor activity of mitomycin C conjugated with anti-α-fetoprotein antibody by a novel method of conjugation. J. Appl. Biochem. 5:1983;313.
-
(1983)
J. Appl. Biochem.
, vol.5
, pp. 313
-
-
Kato, Y.1
Tsukada, Y.2
Hara, T.3
Hirai, H.4
-
25
-
-
0027225273
-
Immunochemotherapy of human colon carcinoma xenografts in nude mice using combinations of idarubicin-monoclonal antibody conjugates
-
Smyth M.J., Foster H.M., Andrew S.M., Teh J.G., Krauer K., McKenzie I.F.C., Pietersz G.A. Immunochemotherapy of human colon carcinoma xenografts in nude mice using combinations of idarubicin-monoclonal antibody conjugates. Immunol. Cell Biol. 71:1993;167-179.
-
(1993)
Immunol. Cell Biol.
, vol.71
, pp. 167-179
-
-
Smyth, M.J.1
Foster, H.M.2
Andrew, S.M.3
Teh, J.G.4
Krauer, K.5
McKenzie, I.F.C.6
Pietersz, G.A.7
-
26
-
-
0023152552
-
Selective enhancement of anti-tumor activity of N-acetyl melphalan upon conjugation to monoclonal antibodies
-
Smyth M.J., Pietersz G.A., McKenzie I.F.C. Selective enhancement of anti-tumor activity of N-acetyl melphalan upon conjugation to monoclonal antibodies. Cancer Res. 47:1987;62-69.
-
(1987)
Cancer Res.
, vol.47
, pp. 62-69
-
-
Smyth, M.J.1
Pietersz, G.A.2
McKenzie, I.F.C.3
-
27
-
-
0028067743
-
Antibody-targeted drugs for the therapy of cancer
-
Pietersz G.A., Krauer K. Antibody-targeted drugs for the therapy of cancer. J. Drug Targeting. 2:1994;183-215.
-
(1994)
J. Drug Targeting
, vol.2
, pp. 183-215
-
-
Pietersz, G.A.1
Krauer, K.2
-
28
-
-
0003046450
-
Conjugates of antibodies with cytotoxic drugs
-
in: C.W. Vogel (Ed.) Oxford University Press, New York
-
M. Sela, E. Hurwitz, Conjugates of antibodies with cytotoxic drugs, in: C.W. Vogel (Ed.), Immunoconjugates, Oxford University Press, New York, 1987, pp. 189-216.
-
(1987)
Immunoconjugates
, pp. 189-216
-
-
Sela, M.1
Hurwitz, E.2
-
29
-
-
0025398273
-
The linkage of cytotoxic drugs to antibodies for the treatment of cancer
-
Pietersz G.A. The linkage of cytotoxic drugs to antibodies for the treatment of cancer. Bioconjugate Chem. 1:1990;89-95.
-
(1990)
Bioconjugate Chem.
, vol.1
, pp. 89-95
-
-
Pietersz, G.A.1
-
30
-
-
0019170967
-
Soluble macromolecules as carriers for daunorubicin
-
Hurwitz E., Wilchek M., Pitha J. Soluble macromolecules as carriers for daunorubicin. J. Appl. Biochem. 2:1980;25-35.
-
(1980)
J. Appl. Biochem.
, vol.2
, pp. 25-35
-
-
Hurwitz, E.1
Wilchek, M.2
Pitha, J.3
-
31
-
-
0023890683
-
Nature of linkage and mode of action of methotrexate conjugated with antitumor antibodies: Implications for future preparation of conjugates
-
Endo N., Takeda Y., Umemoto N., Kishida K., Watanabe K., Saito M., Kato Y., Hara T. Nature of linkage and mode of action of methotrexate conjugated with antitumor antibodies: implications for future preparation of conjugates. Cancer Res. 48:1988;3330-3335.
-
(1988)
Cancer Res.
, vol.48
, pp. 3330-3335
-
-
Endo, N.1
Takeda, Y.2
Umemoto, N.3
Kishida, K.4
Watanabe, K.5
Saito, M.6
Kato, Y.7
Hara, T.8
-
32
-
-
0006052482
-
A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: In vitro and in vivo studies
-
Trouet A., Masquelier M., Baurain R., Campeneere D.D.-D. A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: in vitro and in vivo studies. Proc. Natl. Acad. Sci. USA. 79:1982;626-629.
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 626-629
-
-
Trouet, A.1
Masquelier, M.2
Baurain, R.3
Campeneere, D.D.-D.4
-
33
-
-
0024557322
-
Preparation and in vitro evaluation of a methotrexate-anti-MM46 monoclonal antibody conjugate via an oligopeptide spacer
-
Umemoto N., Kato Y., Endo N., Takeda Y., Hara T. Preparation and in vitro evaluation of a methotrexate-anti-MM46 monoclonal antibody conjugate via an oligopeptide spacer. Int. J. Cancer. 43:1989;677-684.
-
(1989)
Int. J. Cancer
, vol.43
, pp. 677-684
-
-
Umemoto, N.1
Kato, Y.2
Endo, N.3
Takeda, Y.4
Hara, T.5
-
34
-
-
0019786031
-
Cis-Aconityl spacer between daunomycin and macromolecular carriers: A model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate
-
Shen W.-C., Ryser H.J.-P. cis-Aconityl spacer between daunomycin and macromolecular carriers: a model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate. Biochem. Biophys. Res. Commun. 102:1981;1048-1054.
-
(1981)
Biochem. Biophys. Res. Commun.
, vol.102
, pp. 1048-1054
-
-
Shen, W.-C.1
Ryser, H.J.-P.2
-
35
-
-
0023730095
-
Pharmacokinetics and mechanism of action of a doxorubicin-monoclonal 9.2.27 conjugate directed to a human melanoma proteoglycan
-
Yang H.M., Reisfeld R.A. Pharmacokinetics and mechanism of action of a doxorubicin-monoclonal 9.2.27 conjugate directed to a human melanoma proteoglycan. J. Natl. Cancer Inst. 80:1988;1154-1157.
-
(1988)
J. Natl. Cancer Inst.
, vol.80
, pp. 1154-1157
-
-
Yang, H.M.1
Reisfeld, R.A.2
-
36
-
-
0023781775
-
Superiority of an acid-labile daunorubicin-monoclonal antibody immunoconjugate compared to free drug
-
Dillman R.O., Johnson D.E., Shawler D.L., Koziol J.A. Superiority of an acid-labile daunorubicin-monoclonal antibody immunoconjugate compared to free drug. Cancer Res. 48:1988;6097-6102.
-
(1988)
Cancer Res.
, vol.48
, pp. 6097-6102
-
-
Dillman, R.O.1
Johnson, D.E.2
Shawler, D.L.3
Koziol, J.A.4
-
37
-
-
0024561482
-
New antitumor monoclonal antibody-Vinca conjugate LY203725 and related compounds: Design, preparation and representative in vivo activity
-
Laguzza B.C., Nichols C.L., Briggs S.L., Cullinan D.J., Johnson D.A., Starling J.J., Baker A.l., Bumol T.F., Corvalan J.R.F. New antitumor monoclonal antibody-Vinca conjugate LY203725 and related compounds: design, preparation and representative in vivo activity. J. Med. Chem. 32:1989;548-555.
-
(1989)
J. Med. Chem.
, vol.32
, pp. 548-555
-
-
Laguzza, B.C.1
Nichols, C.L.2
Briggs, S.L.3
Cullinan, D.J.4
Johnson, D.A.5
Starling, J.J.6
Baker, A.L.7
Bumol, T.F.8
Corvalan, J.R.F.9
-
38
-
-
0025185802
-
Evaluation in vitro of adriamycin immunoconjugates synthesized using an acid-sensitive hydrazone link
-
Greenfield R.S., Kaneko T., Daues A., Edson M.A., Fitzgerald K.A., Olech L.J., Grattan J.A., Spitalny G.L., Braslawsky G.R. Evaluation in vitro of adriamycin immunoconjugates synthesized using an acid-sensitive hydrazone link. Cancer Res. 50:1990;6600-6607.
-
(1990)
Cancer Res.
, vol.50
, pp. 6600-6607
-
-
Greenfield, R.S.1
Kaneko, T.2
Daues, A.3
Edson, M.A.4
Fitzgerald, K.A.5
Olech, L.J.6
Grattan, J.A.7
Spitalny, G.L.8
Braslawsky, G.R.9
-
39
-
-
0023710359
-
P-Benzylthiocarbamoyl-aspartyl-daunorubicin-substituted polytrisacryl. A new drug acid-labile arm-carrier conjugate
-
Daussin F., Boschetti E., Delmotte F., Monsigny M. p-Benzylthiocarbamoyl-aspartyl-daunorubicin-substituted polytrisacryl. A new drug acid-labile arm-carrier conjugate. Eur. J. Biochem. 176:1988;625-628.
-
(1988)
Eur. J. Biochem.
, vol.176
, pp. 625-628
-
-
Daussin, F.1
Boschetti, E.2
Delmotte, F.3
Monsigny, M.4
-
40
-
-
0026073686
-
Inhibition of human renal cancer by monoclonal antibody-linked methotrexate in an ascites tumor model
-
Singh M., Ghose T., Kralovec J., Blair A.H., Belitsky P. Inhibition of human renal cancer by monoclonal antibody-linked methotrexate in an ascites tumor model. Cancer Immunol Immunother. 32:1991;331-334.
-
(1991)
Cancer Immunol Immunother.
, vol.32
, pp. 331-334
-
-
Singh, M.1
Ghose, T.2
Kralovec, J.3
Blair, A.H.4
Belitsky, P.5
-
41
-
-
0023583876
-
Monoclonal antibody-drug conjugates for site-directed chemotherapy: Preclinical pharmacology and toxicology studies
-
Johnson I.S., Spearman M.E., Todd G.C., Zimmerman J.L., Bumol T.F. Monoclonal antibody-drug conjugates for site-directed chemotherapy: preclinical pharmacology and toxicology studies. Cancer Treatment Revs. 14:1987;193-196.
-
(1987)
Cancer Treatment Revs.
, vol.14
, pp. 193-196
-
-
Johnson, I.S.1
Spearman, M.E.2
Todd, G.C.3
Zimmerman, J.L.4
Bumol, T.F.5
-
42
-
-
0031031895
-
Effect of linker variation on the stability, potency and efficacy of carcinoma-reactive BR64-Doxorubicin immunoconjugates
-
Trail P.A., Willner D., Knipe J., Henderson A.J., Lasch S.J., Zoekler M.E., Trailsmith M.D., Doyle T.W., King H.D., Casazza A.M., Braslawsky G.R., Brown J., Hofstead S.J., Greenfield R.S., Firestone R.A., Mosure K., Kadow K.F., Yang M.B., Hellstrom K.E., Hellstrom I. Effect of linker variation on the stability, potency and efficacy of carcinoma-reactive BR64-Doxorubicin immunoconjugates. Cancer Res. 57:1997;100-105.
-
(1997)
Cancer Res.
, vol.57
, pp. 100-105
-
-
Trail, P.A.1
Willner, D.2
Knipe, J.3
Henderson, A.J.4
Lasch, S.J.5
Zoekler, M.E.6
Trailsmith, M.D.7
Doyle, T.W.8
King, H.D.9
Casazza, A.M.10
Braslawsky, G.R.11
Brown, J.12
Hofstead, S.J.13
Greenfield, R.S.14
Firestone, R.A.15
Mosure, K.16
Kadow, K.F.17
Yang, M.B.18
Hellstrom, K.E.19
Hellstrom, I.20
more..
-
43
-
-
0027218284
-
Cure of xenografted human carcinomas by BR96-Doxorubicin immunoconjugates
-
Trail P.A., Willner D., Lasch S.J., Henderson A.J., Hofstead S., Casazza A.M., Firestone R.A., Hellstrom I., Hellstrom K.E. Cure of xenografted human carcinomas by BR96-Doxorubicin immunoconjugates. Science. 261:1993;212-215.
-
(1993)
Science
, vol.261
, pp. 212-215
-
-
Trail, P.A.1
Willner, D.2
Lasch, S.J.3
Henderson, A.J.4
Hofstead, S.5
Casazza, A.M.6
Firestone, R.A.7
Hellstrom, I.8
Hellstrom, K.E.9
-
44
-
-
0030050856
-
Preparation and functional evaluation of new doxorubicin immunoconjugates containing an acid-sensitive linker on small cell lung cancer
-
Froesch B.A., Stahel R.A. Preparation and functional evaluation of new doxorubicin immunoconjugates containing an acid-sensitive linker on small cell lung cancer. Cancer Immunol. Immunother. 42:1996;55-63.
-
(1996)
Cancer Immunol. Immunother.
, vol.42
, pp. 55-63
-
-
Froesch, B.A.1
Stahel, R.A.2
-
45
-
-
0028945068
-
Stabilization of chimeric BR96-Doxorubicin immunoconjugates
-
Barbour N.P., Paborji M., Alexander T.C., Coppola W.P., Bogardus J.P. Stabilization of chimeric BR96-Doxorubicin immunoconjugates. Pharm. Res. 12:1995;215-222.
-
(1995)
Pharm. Res.
, vol.12
, pp. 215-222
-
-
Barbour, N.P.1
Paborji, M.2
Alexander, T.C.3
Coppola, W.P.4
Bogardus, J.P.5
-
46
-
-
0021168147
-
Tumor and tissue distribution of a methotrexate-anti-EL4 immunoglobulin conjugate in EL4 lymphoma-bearing mice
-
Uadia P., Blair A.H., Ghose T. Tumor and tissue distribution of a methotrexate-anti-EL4 immunoglobulin conjugate in EL4 lymphoma-bearing mice. Cancer Res. 44:1984;4263-4266.
-
(1984)
Cancer Res.
, vol.44
, pp. 4263-4266
-
-
Uadia, P.1
Blair, A.H.2
Ghose, T.3
-
47
-
-
0001577078
-
Doxorubicin conjugated with a monoclonal antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude mice
-
Yang H.M., Reisfeld R.A. Doxorubicin conjugated with a monoclonal antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude mice. Proc. Natl. Acad. Sci. USA. 85:1988;1189-1193.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 1189-1193
-
-
Yang, H.M.1
Reisfeld, R.A.2
-
48
-
-
0025027766
-
Antitumor activity of adriamycin (hydrazone-linked) immunoconjugates compared with free adriamycin and specificity of tumor cell killing
-
Braslawsky G.R., Edson M.A., Pearce W., Kaneko T., Greenfield R.S. Antitumor activity of adriamycin (hydrazone-linked) immunoconjugates compared with free adriamycin and specificity of tumor cell killing. Cancer Res. 50:1990;6608-6614.
-
(1990)
Cancer Res.
, vol.50
, pp. 6608-6614
-
-
Braslawsky, G.R.1
Edson, M.A.2
Pearce, W.3
Kaneko, T.4
Greenfield, R.S.5
-
49
-
-
0024323595
-
Inhibition of human tumor growth in nude mice by a conjugate of doxorubicin with monoclonal antibody to epidermal growth factor receptor
-
Aboud-Pirak E., Hurwitz E., Bellot F., Schlessinger J., Sela M. Inhibition of human tumor growth in nude mice by a conjugate of doxorubicin with monoclonal antibody to epidermal growth factor receptor. Proc. Natl. Acad. Sci. USA. 86:1989;3778-3781.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 3778-3781
-
-
Aboud-Pirak, E.1
Hurwitz, E.2
Bellot, F.3
Schlessinger, J.4
Sela, M.5
-
50
-
-
0024511770
-
In vivo efficacy of monoclonal antibody-drug conjugates of three different subisotypes which bind the human tumor-associated antigen defined by the KS1/4 monoclonal antibody
-
Starling J.J., Maciak R.S., Hinson N.A., Nichols C.L., Briggs S.L., Laguzza B.C. In vivo efficacy of monoclonal antibody-drug conjugates of three different subisotypes which bind the human tumor-associated antigen defined by the KS1/4 monoclonal antibody. Cancer Immunol Immunother. 28:1989;171-178.
-
(1989)
Cancer Immunol Immunother.
, vol.28
, pp. 171-178
-
-
Starling, J.J.1
Maciak, R.S.2
Hinson, N.A.3
Nichols, C.L.4
Briggs, S.L.5
Laguzza, B.C.6
-
51
-
-
0025368366
-
Antitumor activity of the monoclonal antibody-Vinca alkaloid immunoconjugate LY203725 (KS1/4-4-desacetylvinblastine-3-carboxhydrazide) in a nude mouse model of human ovarian cancer
-
Apelgren L.D., Zimmerman D.L., Bruggs S.L., Bumol T.F. Antitumor activity of the monoclonal antibody-Vinca alkaloid immunoconjugate LY203725 (KS1/4-4-desacetylvinblastine-3-carboxhydrazide) in a nude mouse model of human ovarian cancer. Cancer Res. 50:1990;3540-3544.
-
(1990)
Cancer Res.
, vol.50
, pp. 3540-3544
-
-
Apelgren, L.D.1
Zimmerman, D.L.2
Bruggs, S.L.3
Bumol, T.F.4
-
52
-
-
0025288274
-
Phase I clinical comparative study of monoclonal antibody KS1/4 and KS1-4-methotrexate immunoconjugate in patients with non-small cell lung carcinoma
-
Elias D.J., Hirschowitz L., Kline L.E., Kroener J.F., Dillman R.O., Walker L.E., Robb J.A., Timms R.M. Phase I clinical comparative study of monoclonal antibody KS1/4 and KS1-4-methotrexate immunoconjugate in patients with non-small cell lung carcinoma. Cancer Res. 50:1990;4154-4159.
-
(1990)
Cancer Res.
, vol.50
, pp. 4154-4159
-
-
Elias, D.J.1
Hirschowitz, L.2
Kline, L.E.3
Kroener, J.F.4
Dillman, R.O.5
Walker, L.E.6
Robb, J.A.7
Timms, R.M.8
-
53
-
-
0028172671
-
Monoclonal antibody KS1-4-methotrexate immunoconjugate studies in non-small cell lung carcinoma
-
Elias D.J., Kline L.E., Robbins B.A., Johnson H.C.L., Pekny K., Benz M., Robb J.A., Walker L.E., Kosty M., Dillman R.O. Monoclonal antibody KS1-4-methotrexate immunoconjugate studies in non-small cell lung carcinoma. Am. J. Respir. Crit. Care Med. 150:1994;1114-1122.
-
(1994)
Am. J. Respir. Crit. Care Med.
, vol.150
, pp. 1114-1122
-
-
Elias, D.J.1
Kline, L.E.2
Robbins, B.A.3
Johnson, H.C.L.4
Pekny, K.5
Benz, M.6
Robb, J.A.7
Walker, L.E.8
Kosty, M.9
Dillman, R.O.10
-
54
-
-
0025095672
-
Disposition of a murine monoclonal antibody-Vinca conjugate (KS1/4-DAVLB) in patients with adenocarcinoma
-
Schneck D., Butler F., Dugan W., Littrell D., Petersen B., Bowsher R., DeLong A., Dorrbecker S. Disposition of a murine monoclonal antibody-Vinca conjugate (KS1/4-DAVLB) in patients with adenocarcinoma. Clin. Pharmacol, Ther. 47:1990;36-41.
-
(1990)
Clin. Pharmacol, Ther.
, vol.47
, pp. 36-41
-
-
Schneck, D.1
Butler, F.2
Dugan, W.3
Littrell, D.4
Petersen, B.5
Bowsher, R.6
DeLong, A.7
Dorrbecker, S.8
-
55
-
-
0001994518
-
Phase I studies with a murine monoclonal antibody-Vinca conjugate (KS1-4-DAVLB) in patients with adenocarcinoma
-
Schneck D., Butler F., Dugan W., Littrell D., Dorrbecker S., Petersen B., Bowsher R., DeLong A., Zimmerman J. Phase I studies with a murine monoclonal antibody-Vinca conjugate (KS1-4-DAVLB) in patients with adenocarcinoma. Antibody Immunoconjugates and Radiopharm. 2:1989;93-100.
-
(1989)
Antibody Immunoconjugates and Radiopharm.
, vol.2
, pp. 93-100
-
-
Schneck, D.1
Butler, F.2
Dugan, W.3
Littrell, D.4
Dorrbecker, S.5
Petersen, B.6
Bowsher, R.7
DeLong, A.8
Zimmerman, J.9
-
56
-
-
0000397322
-
Parametric model for BR96-doxorubicin pharamacokinetics (PK) in cancer patients
-
Grasela D., LoBuglio A., Murray J.L., Raymond R., Birkhofer M., Summerill R., Stewart M. Parametric model for BR96-doxorubicin pharamacokinetics (PK) in cancer patients. Proc. Am. Assoc. Cancer Res. 36:1995;1393.
-
(1995)
Proc. Am. Assoc. Cancer Res.
, vol.36
, pp. 1393
-
-
Grasela, D.1
LoBuglio, A.2
Murray, J.L.3
Raymond, R.4
Birkhofer, M.5
Summerill, R.6
Stewart, M.7
-
57
-
-
0008390806
-
In: Antibodies as carriers of cytotoxicity
-
H. Huber, W. Queiber (Eds.) Karger, Basel
-
H.-H. Sedlacek, G. Seemann, D. Hoffmann, J. Czech, P. Lorenz, C. Kolar, K. Bosslet, in: Antibodies as carriers of cytotoxicity. H. Huber, W. Queiber (Eds.), Contrib. Oncology, Karger, Basel, 43, 1992, pp. 75-82.
-
(1992)
Contrib. Oncology
, vol.43
, pp. 75-82
-
-
Sedlacek, H.-H.1
Seemann, G.2
Hoffmann, D.3
Czech, J.4
Lorenz, P.5
Kolar, C.6
Bosslet, K.7
-
58
-
-
9444235053
-
Eradication of large colon tumor xenografts by targeted delivery of maytansinoids
-
Liu C., Tadayoni B.M., Bourret L.A., Mattocks K.M., Derr S.M., Widdison W.C., Kedersha N.L., Ariniello P.D., Goldmacher V.S., Lambert J.M., Blättler W.A., Chari R.V.J. Eradication of large colon tumor xenografts by targeted delivery of maytansinoids. Proc. Natl. Acad. Sci. USA. 93:1996;8618-8623.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8618-8623
-
-
Liu, C.1
Tadayoni, B.M.2
Bourret, L.A.3
Mattocks, K.M.4
Derr, S.M.5
Widdison, W.C.6
Kedersha, N.L.7
Ariniello, P.D.8
Goldmacher, V.S.9
Lambert, J.M.10
Blättler, W.A.11
Chari, R.V.J.12
-
59
-
-
0026593928
-
Immunoconjugates containing novel maytansinoids: Promising anticancer drugs
-
Chari R.V.J., Martell B.A., Gross J.L., Cook S.B., Shah S.A., Blättler W.A., McKenzie S.J., Goldmacher V.S. Immunoconjugates containing novel maytansinoids: promising anticancer drugs. Cancer Res. 52:1992;127-131.
-
(1992)
Cancer Res.
, vol.52
, pp. 127-131
-
-
Chari, R.V.J.1
Martell, B.A.2
Gross, J.L.3
Cook, S.B.4
Shah, S.A.5
Blättler, W.A.6
McKenzie, S.J.7
Goldmacher, V.S.8
-
60
-
-
0029093035
-
Enhancement of the selectivity and anti-tumor activity of a CC-1065 analogue through immunoconjugate formation
-
Chari R.V.J., Jackel K.A., Bourret L.A., Derr S.M., Tadayoni B.M., Mattocks K.M., Shah S.A., Liu C., Blättler W.A., Goldmacher V.S. Enhancement of the selectivity and anti-tumor activity of a CC-1065 analogue through immunoconjugate formation. Cancer Res. 55:1995;4079-4084.
-
(1995)
Cancer Res.
, vol.55
, pp. 4079-4084
-
-
Chari, R.V.J.1
Jackel, K.A.2
Bourret, L.A.3
Derr, S.M.4
Tadayoni, B.M.5
Mattocks, K.M.6
Shah, S.A.7
Liu, C.8
Blättler, W.A.9
Goldmacher, V.S.10
-
61
-
-
0027194197
-
Preparation and characterization of monoclonal antibody conjugates of the calicheamicins: A novel and potent family of antitumor antibiotics
-
Hinman L.M., Hamaan P.R., Wallace R., Menendez A.T., Durr F.E., Upeslacis J. Preparation and characterization of monoclonal antibody conjugates of the calicheamicins: a novel and potent family of antitumor antibiotics. Cancer Res. 53:1993;3536-3542.
-
(1993)
Cancer Res.
, vol.53
, pp. 3536-3542
-
-
Hinman, L.M.1
Hamaan, P.R.2
Wallace, R.3
Menendez, A.T.4
Durr, F.E.5
Upeslacis, J.6
-
62
-
-
0025491169
-
Antibody conjugates with morpholinodoxorubicin and acid-cleavable linkers
-
Mueller B.M., Wrasidlo W.A., Reisfeld R.A. Antibody conjugates with morpholinodoxorubicin and acid-cleavable linkers. Bioconjugate Chem. 1:1990;325-330.
-
(1990)
Bioconjugate Chem.
, vol.1
, pp. 325-330
-
-
Mueller, B.M.1
Wrasidlo, W.A.2
Reisfeld, R.A.3
-
63
-
-
0016724870
-
Antimitotic activity of the potent tumor inhibitor maytansine
-
Remillard S., Rebhun L.I., Howie G.A., Kupchan S.M. Antimitotic activity of the potent tumor inhibitor maytansine. Science. 189:1977;1002-1005.
-
(1977)
Science
, vol.189
, pp. 1002-1005
-
-
Remillard, S.1
Rebhun, L.I.2
Howie, G.A.3
Kupchan, S.M.4
-
64
-
-
0022586257
-
The chemistry, mechanism of action and biological properties of CC-1065; A potent antitumor antibiotic
-
Reynolds V.L., McGovren J.P., Hurley L.H. The chemistry, mechanism of action and biological properties of CC-1065; a potent antitumor antibiotic. J. Antibiot. 39:1986;319-334.
-
(1986)
J. Antibiot.
, vol.39
, pp. 319-334
-
-
Reynolds, V.L.1
McGovren, J.P.2
Hurley, L.H.3
-
65
-
-
0001163468
-
Calicheamicins: Discovery, structure, chemistry, and interaction with DNA
-
Lee M.D., Ellestad G.A., Borders D.B. Calicheamicins: discovery, structure, chemistry, and interaction with DNA. Acc. Chem. Res. 24:1991;235-243.
-
(1991)
Acc. Chem. Res.
, vol.24
, pp. 235-243
-
-
Lee, M.D.1
Ellestad, G.A.2
Borders, D.B.3
|