Synthesis of highly potent second-generation taxoids through effective kinetic resolution coupling of racemic β-lactams with baccatins

Chirality

Volumn 12, Issue 5-6, 2000, Pages 431-441

  Lin, Songnian ^a   Geng, Xudong ^a   Qu, Chuanxing ^a   Tynebor, Robert ^a   Gallagher, David J ^a   Pollina, Elizabeth ^a   Rutter, Jessica ^a   Ojima, Iwao ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Asymmetric synthesis; Baccatin; Diastereoselective; Docetaxel; Kinetic resolution; Paclitaxel; Second generation taxoids

Indexed keywords

3' DEPHENYL 3' (2 METHYLPROPYL) 10 ACETYLDOCETAXEL 1,14 CARBONIC ACID; BACCATIN DERIVATIVE; BETA LACTAM DERIVATIVE; DOCETAXEL; LITHIUM DERIVATIVE; ORTATAXEL; PACLITAXEL; TAXOID; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHIRALITY; DIASTEREOISOMER; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL; REACTION ANALYSIS;

EID: 0034037058     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(2000)12:5/6<431::AID-CHIR24>3.0.CO;2-M     Document Type: Article

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