Phase I open study of the effects of ascending doses of the cytotoxic immunoconjagate CMB-401 (hCTMO1-calicheamicin) in patients with epithelial ovarian cancer

Annals of Oncology

Volumn 11, Issue 6, 2000, Pages 735-741

  Gillespie, A M ^a   Broadhead, T J ^b   Chan, S Y ^b   Owen, J ^a   Farnsworth, A P ^c   Sopwith, M ^c   Coleman, R E ^a  

^a WESTON PARK HOSPITAL   (United Kingdom)

^b NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^c UCB PHARMA   (Belgium)

Author keywords

Antibody; Calicheamicin; CMB 401; Immunotherapy; Ovarian cancer

Indexed keywords

ANTIBODY CONJUGATE; ANTINEOPLASTIC AGENT; CALICHEAMICIN DERIVATIVE; CMB 401; UNCLASSIFIED DRUG;

ADULT; AGED; ANEMIA; ARTICLE; BLEEDING; CANCER IMMUNOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; GRANULOCYTOPENIA; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER TOXICITY; LUNG TOXICITY; MAXIMUM PERMISSIBLE DOSE; MULTICENTER STUDY; NAUSEA; NEPHROTOXICITY; OVARY CANCER; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEPSIS; SOMNOLENCE; THROMBOCYTOPENIA; VOMITING;

EID: 0033752234     PISSN: 09237534     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008349300781     Document Type: Article

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