Structure of β-amyloid fibrils and its relevance to their neurotoxicity: Implications for the pathogenesis of Alzheimer's disease

Journal of Bioscience and Bioengineering

Volumn 99, Issue 5, 2005, Pages 437-447

  Irie, Kazuhiro ^a   Murakami, Kazuma ^a   Masuda, Yuichi ^a   Morimoto, Akira ^a   Ohigashi, Hajime ^a   Ohashi, Ryutaro ^a   Takegoshi, Kiyonori ^a   Nagao, Masaya ^a   Shimizu, Takahiko ^b   Shirasawa, Takuji ^b  

^a KYOTO UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Alzheimer's disease; Amyloid; A 40; A 42; Cerebral amyloid angiopathy; Familial Alzheimer's disease; Neurotoxicity; Oxidative stress; Solid state nuclear magnetic resonance

Indexed keywords

DISEASES; MOLECULAR STRUCTURE; NEUROLOGY; PATHOLOGY; STRUCTURAL ANALYSIS; TOXICITY;

ALZHEIMER'S DISEASES; CEREBRAL AMYLOID ANGIOPATHY; FIBRILIZATION; NEUROTOXICITY;

PROTEINS;

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42];

ALZHEIMER DISEASE; FAMILIAL DISEASE; FIBER; HUMAN; IN VITRO STUDY; NEUROTOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN AGGREGATION; PROTEIN STRUCTURE; REVIEW; SOLID STATE; VASCULAR AMYLOIDOSIS;

EID: 21044431809     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1263/jbb.99.437     Document Type: Article

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