Aggregation and neurotoxicity of mutant amyloid β (Aβ) peptides with proline replacement: Importance of turn formation at positions 22 and 23

Biochemical and Biophysical Research Communications

Volumn 295, Issue 2, 2002, Pages 306-311

  Morimoto, Akira ^a   Irie, Kazuhiro ^a   Murakami, Kazuma ^a   Ohigashi, Hajime ^a   Shindo, Mayumi ^b   Nagao, Masaya ^a   Shimizu, Takahiko ^c   Shirasawa, Takuji ^c  

^a KYOTO UNIVERSITY   (Japan)

^b Applied Biosystems Japan Ltd   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Alzheimer's disease (AD); Amyloid (A ); MTT; PC12; Proline; Thioflavin T (Th T); Turn

Indexed keywords

AMYLOID BETA PROTEIN; PROLINE;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BETA SHEET; CONTROLLED STUDY; NEUROTOXICITY; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; RAT;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MOLECULAR SEQUENCE DATA; PC12 CELLS; PEPTIDE FRAGMENTS; PROLINE; PROTEIN STRUCTURE, SECONDARY; RATS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0036069380     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)00670-8     Document Type: Article

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