Novel amyloid precursor protein gene missense mutation (D678N) in probable familial Alzheimer's disease

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 75, Issue 7, 2004, Pages 1039-1042

  Wakutani, Y ^a   Watanabe, K ^b   Adachi, Y ^a   Wada Isoe, K ^a   Urakami, K ^a   Ninomiya, H ^a   Saido, T C ^d   Hashimoto, T ^c   Iwatsubo, T ^c   Nakashima, K ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b Watanabe Hospital   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; AMYLOID PRECURSOR PROTEIN; GENOMIC DNA;

ADULT; AGED; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ARTICLE; CEREBROVASCULAR ACCIDENT; CHROMOSOME BAND; CONTROLLED STUDY; DISEASE COURSE; EXON; FAMILIAL DISEASE; FEMALE; GENE MUTATION; GENETIC ANALYSIS; HETEROZYGOSITY; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MISSENSE MUTATION; NEURORADIOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROBABILITY; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM;

AGED; ALZHEIMER DISEASE; ATROPHY; BRAIN; CARRIER PROTEINS; COGNITION DISORDERS; EXONS; GENE EXPRESSION; HUMANS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; MUTATION, MISSENSE; NEUROPSYCHOLOGICAL TESTS; PEDIGREE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 2542424288     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.2003.010611     Document Type: Article

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