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Volumn 1, Issue 14, 2003, Pages 2468-2473

Synthesis of potent β-secretase inhibitors containing a hydroxyethylamine dipeptide isostere and their structure-activity relationship studies

(4) Tamamura, Hirokazu a Kato, Terukazu a Otaka, Akira a Fujii, Nobutaka a

a KYOTO UNIVERSITY (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; ENZYME KINETICS; ESTERIFICATION; MOLECULAR STRUCTURE;

EPIMERIZATION;

ENZYME INHIBITION;

ASPARTIC PROTEINASE; DIPEPTIDE; ETHYLAMINE; HETEROCYCLIC COMPOUND; ISOENZYME; OLIGOPEPTIDE; PROTEINASE INHIBITOR; RECOMBINANT PROTEIN;

ACYLATION; AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; ESTERIFICATION; GENETICS; HUMAN; IC 50; MOLECULAR MIMICRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ACYLATION; AMINO ACID SEQUENCE; ASPARTIC ENDOPEPTIDASES; AZA COMPOUNDS; DIPEPTIDES; ESTERIFICATION; ETHYLAMINES; HUMANS; INHIBITORY CONCENTRATION 50; ISOENZYMES; MOLECULAR MIMICRY; OLIGOPEPTIDES; PROTEASE INHIBITORS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0141618463 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/b304842j Document Type: Article

Times cited : (75)

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