Toxicity of Dutch (E22Q) and flemish (A21G) mutant amyloid β proteins to human cerebral microvessel and aortic smooth muscle cells

Stroke

Volumn 31, Issue 2, 2000, Pages 534-538

  Wang, Zhenzhen ^b   Natté, Remco ^b   Berliner, Judith A ^b   Van Duinen, Sjoerd G ^b   Vinters, Harry V ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

Amyloid; Cerebral circulation; Microcirculation; Muscle, smooth; Mutation

Indexed keywords

AMYLOID BETA PROTEIN;

AORTA; ARTICLE; BRAIN BLOOD VESSEL; BRAIN CIRCULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; NEUROTOXICITY; POINT MUTATION; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULAR AMYLOIDOSIS;

EID: 0033951944     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.31.2.534     Document Type: Article

References (26)

1. Kawai M, Kalaria RN, Cras P, Siedlak SL, Velasco ME, Shelton ER, Chan HW, Greenberg BD, Perry G. Degeneration of vascular smooth muscle cells in cerebral amyloid angiopathy of Alzheimer disease. Brain Res. 1993;623:142-146.
2. Vinters HV, Wang ZZ, Secor DL. Brain parenchymal and microvascular amyloid in Alzheimer's disease. Brain Pathol. 1996;6:179-195.
3. Glenner GG, Wong CW. Alzheimer's disease and Down's syndrome: sharing of unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Commun. 1984;122:1131-1135.
4. Maat-Schieman MLC, van Duinen SG, Bornebroek M, Haan J, Roos RAC. Hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D), II: a review of histopathological aspects. Brain Pathol. 1996;6:115-120.
5. Van Duinen SG, Castano EM, Bots GTAM, Luyendijk W, Frangione B. Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease. Proc Natl Acad Sci U S A. 1987; 84:5991-5994.
6. Vinters HV, Secor DL, Read SL, Frazee JG, Tomiyasu U, Stanley TM, Ferreiro JA, Akers M-A. Microvasculature in brain biopsy specimens from patients with Alzheimer's disease: an immunohistochemical and ultrastructural study. Ultrastruct Pathol. 1994;18:333-348.
7. Wisniewski HM, Fraçkowiak J, Zóltowska A, Kim KS. Vascular β-amyloid in Alzheimer's disease angiopathy is produced by proliferating and degenerating smooth muscle cells. Int J Exp Clin Invest. 1994; 1:8-16.
8. Wisniewski HM, Wegiel J. β-Amyloid formation by myocytes of leptomeningeal vessels. Acta Neuropathol (Berl). 1994;87:233-241.
9. Natté R, Vinters HV, Maat-Schieman MLC, Bornebroek M, Haan J, Roos RAC, van Duinen SG. Microvasculopathy is associated with the number of cerebrovascular lesions in hereditary cerebral hemorrhage with amyloidosis, Dutch type. Stroke. 1998;29:1588-1594.
10. Vinters HV, Natté R. Maat-Schieman MLC, Van Duinen SG, Hegeman-Kleinn I, Welling-Graafland C, Haan J, Roos RAC. Secondary microvascular degeneration in amyloid angiopathy of patients with hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D). Acta Neuropathol (Berl). 1998;95:235-244.
11. Chartier-Harlin MC, Crawford F, Houlden H, Warren A, Hughes D, Fidani L, Goate A, Rossor M, Roques P, Hardy J, Mullan M. Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene. Nature. 1991; 353:844-846.
12. Haass C, Hung AY, Selkoe DJ, Teplow DB. Mutations associated with a locus for familial Alzheimer disease results in alternative processing of amyloid precursor protein. J Biol Chem. 1994;269:17741-17748.
13. Hendriks L, van Duijn CM, Cras P, Cruts M, van Hul W, van Harskamp F, Warren A, McInnis MG, Antonarakis SE, Martin J J, Hofman A, van Broeckhoven C. Presenik dementia and cerebral hemorrhage linked to a mutation at codon 692 of the β-amyloid precursor protein gene. Nature Genet. 1992;1:218-221.
14. Lannfelt L, Bogdanovic N, Appelgren H, Axelman K, Lilius L, Hansson G, Schenk D, Hardy J, Winblad B. Amyloid precursor protein mutations causes Alzheimer's disease in a Swedish family. Neurosci Lett. 1994; 168:254-256.
15. Murrel J, Farlow M, Ghetti B, Benson MD. A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. Science. 1991;254:97-99.
16. Cras P, van Harskamp F, Hendriks L, Ceuterick C, van Duijn CM, Stefanko SZ, Hofman A, Kros JM, van Boreckhoven C, Martin JJ. Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP692 Ala→Gly mutation. Acta Neuropathol (Berl). 1998;96:253-260.
17. Davis J, van Nostrand WE. Enhanced pathologic properties of Dutch-type mutant amyloid β-protein. Proc Natl Acad Sci U S A. 1996;93:2996-3000.
18. Cook BH, Granger HJ, Granger DN, Taylor AE, Smith EE. Metabolic profiles of canine cerebrovascular tree: a histochemical study. Stroke. 1978;9:165-168.
19. Nakamura A, Isoyama S, Watanabe T, Katoh M, Sawai T. Heterogeneous smooth muscle cell populations derived from small and larger arteries. Microvasc Res. 1998;55:14-28.
20. Vinters HV, Reave S, Costello P, Girvin JP, Moore SA. Isolation and culture of cells derived from human cerebral microvessels. Cell Tissue Res. 1987;249:657-667.
21. Navab M, Hough GP, Stevenson LW, Drinkwater DC, Lakes H, Fogelman AM. Monocyte migration into the subendothelial space of a co-culture of adult human aortic endothelial and smooth muscle cells. J Clin Invest. 1988;82:1853-1863.
22. De Jonghe C, Zehr C, Yager D, Prada CM, Younkin S, Hendriks L, Van Broeckhoven C, Eckman CB. Flemish and Dutch mutations in amyloid β precursor protein have different effects on amyloid β secretion. Neurobiol Dis. 1998;5:281-286.
23. 21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid β/A4 peptide. Neurosci Lett. 1993;161: 17-20.
24. Walsh DM, Lomakin A, Benedek GB, Condron MM, Teplow DB. Amyloid beta-protein fibrillogenesis: detection of a 7rotofibrillar intermediate. J Biol Chem. 1997;272:22364-22372.
25. Wisniewski T, Ghiso J, Frangione B. Peptides homologous to the amyloid protein of Alzheimer disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation. Biochem Biophys Res Commun. 1991;179:1247-1254.
26. van Nostrand WE, Rozemuller AJM, Chung R, Cotman CW, Saporito-Irwin SM. Amyloid β-protein precursor in cultured leptomeningeal smooth muscle cells. Int J Exp Clin Invest. 1994;1:1-8.