Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans

Psychopharmacology

Volumn 168, Issue 4, 2003, Pages 446-454

  Grillon, Christian ^a   Cordova, Jeremy ^b   Levine, Louise R ^c   Morgan III, Charles A ^b  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

Anxiolytic; Darkness; Fear; Fear potentiated startle; Glutamate; LY354740

Indexed keywords

ANXIOLYTIC AGENT; EGLUMETAD; GLUTAMIC ACID; METABOTROPIC RECEPTOR AGONIST; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DARKNESS; DRUG EFFECT; ELECTRODE; ELECTROSTIMULATION; FEAR; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NEUROTRANSMISSION; NORMAL HUMAN; PRIORITY JOURNAL; SHORT TERM MEMORY; STARTLE REFLEX; TRANQUILIZING ACTIVITY;

ADMINISTRATION, ORAL; ADULT; ANTI-ANXIETY AGENTS; ANXIETY; BICYCLO COMPOUNDS; DARKNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRODES; FEAR; FEMALE; HUMANS; MALE; PAIN MEASUREMENT; PHOTIC STIMULATION; REACTION TIME; RECEPTORS, METABOTROPIC GLUTAMATE; STARTLE REACTION;

EID: 0041488670     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-003-1444-8     Document Type: Article

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