In vitro and in vivo characterization of MPEP, an allosteric modulator of the metabotropic glutamate receptor subtype 5: Review article

Amino Acids

Volumn 23, Issue 1-3, 2002, Pages 207-211

  Kuhn, R ^a   Pagano, A ^a   Stoehr, N ^a   Vranesic, I ^a   Flor, P J ^a   Lingenhohl K ^a   Spooren, W ^a   Gentsch, C ^a   Vassout, A ^a   Pilc, A ^b   Gasparini, F ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

Anxiety; Group I metabotropic glutamate receptors; MPEP; Pain; SIB 1757

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 2 METHYL 6 (2 PHENYLVINYL)PYRIDINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 6 METHYL 2 PHENYLAZO 3 PYRIDINOL; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; LIGAND; LY 344595; LY 393675; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR ANTAGONIST; METHIONYLCYSTEINYLPROLYLGLYCINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ALLOSTERISM; ANXIETY NEUROSIS; BINDING AFFINITY; CONCENTRATION RESPONSE; CONFERENCE PAPER; DRUG ACTIVITY; DRUG BINDING SITE; DRUG EFFECT; DRUG INHIBITION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; HUMAN; IC 50; IONTOPHORESIS; NERVE CELL STIMULATION; NONHUMAN; PAIN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN HYDROLYSIS;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; BINDING SITES; BRAIN; EXCITATORY AMINO ACID ANTAGONISTS; LIGANDS; PAIN; PYRIDINES; RECEPTORS, METABOTROPIC GLUTAMATE;

ANIMALIA;

EID: 6444244298     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-001-0130-6     Document Type: Conference Paper

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