Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxycyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes

British Journal of Pharmacology

Volumn 123, Issue 3, 1998, Pages 497-504

  Cartmell, Jayne ^a   Adam, Geo ^a   Chaboz, Sylvie ^a   Henningsen, Robert ^a   Kemp, John A ^a   Klingelschmidt, Agnes ^a   Metzler, Veit ^a   Monsma, Frederick ^a   Schaffhauser, Hervé ^a   Wichmann, Jürgen ^a   Mutel, Vincent ^a,b  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

3H DCG IV; Metabotropic glutamate receptor; mGlu2 receptor; Radioligand binding

Indexed keywords

2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; 2 AMINO 3 PHOSPHONOPROPIONIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); KAINIC ACID; METABOTROPIC RECEPTOR; N ACETYLASPARTYLGLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; TRITIUM; 2-(2,3-DICARBOXYCYCLOPROPYL)GLYCINE; CYCLIC AMP; CYCLOPROPANE DERIVATIVE; DRUG DERIVATIVE; FORSKOLIN; GLYCINE; RECOMBINANT PROTEIN; SULFUR;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL MEMBRANE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; GENETIC TRANSFECTION; ISOTOPE LABELING; MEMBRANE BINDING; NONHUMAN; PH; PRIORITY JOURNAL; RECEPTOR BINDING; TEMPERATURE SENSITIVITY; ANIMAL; BIOSYNTHESIS; HAMSTER; METABOLISM; PROTEIN BINDING; RAT;

ANIMALS; CELL MEMBRANE; CHO CELLS; CRICETINAE; CYCLIC AMP; CYCLOPROPANES; FORSKOLIN; GLYCINE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); PROTEIN BINDING; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; RECOMBINANT PROTEINS; SULFUR RADIOISOTOPES; TRANSFECTION; TRITIUM;

EID: 15644374743     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701647     Document Type: Article

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