Interspersed repeats and other mementos of transposable elements in mammalian genomes

Current Opinion in Genetics and Development

Volumn 9, Issue 6, 1999, Pages 657-663

  Smit, Arian Fa ^a  

^a Axys Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REPETITIVE DNA;

GENE INSERTION; GENOME; HUMAN; MAMMAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVIEW; TRANSCRIPTION REGULATION; TRANSPOSON;

MAMMALIA;

EID: 0032784908     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(99)00031-3     Document Type: Review

References (55)

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47. ••] describe experiments that substantiate the DNA transposon origin of our immune system's recombination mechanism. One can not ask for a better example of a contribution of transposons and of the quirky nature of evolution.
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52. •] describe two proteins that at first sight appear to be transposases, but turn out to contain large amino-terminal domains derived from cellular genes. The existence of cellular transposase derived proteins with apparently intact active sites like the mariner derivative (Table 3) is intriguing for their potential influence on DNA stability.
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