Exon shuffling by L1 retrotransposition

Science

Volumn 283, Issue 5407, 1999, Pages 1530-1534

  Moran, John V ^a,b   DeBerardinis, Ralph J ^a   Kazazian Jr , Haig H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA; RNA DIRECTED DNA POLYMERASE;

ARTICLE; DNA FLANKING REGION; ENZYME ACTIVITY; EXON; GENE INSERTION; GENETIC TRANSCRIPTION; GENOME; HELA CELL; HUMAN; HUMAN CELL; LONG INTERSPERSED REPEAT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROPOSON; SEQUENCE ANALYSIS;

CODON, INITIATOR; EXONS; EXPRESSED SEQUENCE TAGS; GENE EXPRESSION; GENOME, HUMAN; GENTAMICINS; HELA CELLS; HUMANS; INTRONS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; POLY A; PROMOTER REGIONS (GENETICS); RECOMBINATION, GENETIC; TRANSCRIPTION, GENETIC;

EID: 0033525586     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.283.5407.1530     Document Type: Article

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39. We thank M. Kimberland for excellent technical assistance; A. Lotia for assistance with computer graphics; and J. Boeke, D. Ginsburg, E. Luning Prak, J. Goodier, and E. Ostertag for critical reading of the manuscript. Supported in part by Damon Runyon Postdoctoral fellowship DRG-1332 (J.V.M.) and NIH grant GM45398 (H.H.K.).