Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain

Genome Research

Volumn 10, Issue 11, 2000, Pages 1697-1710

  Onyango, Patrick ^a   Miller, Webb ^b   Lehoczky, Jessica ^c   Leung, Cheuk T ^a   Birren, Bruce ^c   Wheelan, Sarah ^a,d   Dewar, Ken ^c   Feinberg, Andrew P ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b The Pennsylvania State University   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; PROTEIN; PROTEIN P57; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHROMOSOME 7; CONTROLLED STUDY; CPG ISLAND; EXON; FEMALE; FETUS; GENE LOCUS; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC ORGANIZATION; GENOME IMPRINTING; HUMAN; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REGULATOR GENE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CHROMOSOMES, HUMAN, PAIR 11; CONSERVED SEQUENCE; CONTIG MAPPING; CPG ISLANDS; DNA, COMPLEMENTARY; FEMALE; GENOMIC IMPRINTING; HUMANS; INSULIN-LIKE GROWTH FACTOR II; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PROTEINS; RNA, MESSENGER; RNA, UNTRANSLATED; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY;

EID: 0033665147     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.161800     Document Type: Article

References (48)

1. Mechanism of imprinting on mouse distal chromosome 7
2. Imprinting of Igf2 and H19 from a 130 kb YAC transgene
3. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
4. Tandem repeats finder: A program to analyze DNA sequences
5. The Human Genome Project - An overview
6. The Mouse Genome Database (MGD): Expanding genetic and genomic resources for the laboratory mouse
7. Analysis of the quality and utility of random shotgun sequencing at low redundancies
8. The ontogeny of allele-specific methylation associated with imprinted genes in the mouse
9. New goals for the U.S. Human Genome Project: 1998-2003
10. Quality not quantity: The pufferfish genome
11. Comparative sequence analysis of the mouse and human Lgn1/SMA interval
12. Imprinting of a genomic domain of 11p15 and loss of imprinting in cancer: An introduction
13. CpG islands in vertebrate genomes
14. Long human-mouse sequence alignments reveal novel regulatory elements: A reason to sequence the mouse genome
15. CTCF mediates methylation-sensitive enhancer-blocking activity at the 1119/Igf2 locus
16. A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes
17. A novel human homolog of yeast nucleosome assembly protein, 65 kb centromeric to the p57(KIP2) gene, is biallelically expressed in fetal and adult tissues
18. Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13
19. Tumor cell growth arrest caused by subchromosomal transferable DNA fragments from human chromosome 11
20. Two novel genes in the center of the 11p15 imprinted domain escape genomic imprinting
21. Loss of imprinting of a paternally expressed transcript, with antisense orientation to K(v)LQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting
22. Low frequency of p57(KIP2) mutation in Beckwith-Wiedemann syndrome
23. Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements
24. Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons
25. Comparative sequence analysis of 634 kb of the mouse chromosome 16 region of conserved synteny with the human velocardiofacial syndrome region on chromosome 22q11.2
26. Comparative genome sequence analysis of the Bpa/Str region in mouse and Man
27. High throughput fingerprint analysis of large-insert clones
28. The promise of comparative genomics in mammals
29. Use of a novel system for defining a gene imprinting region
30. Relaxation of imprinted genes in human cancer
31. Screening large-insert libraries by hybridization
32. Degree of methylation of transgenes is dependent on gamete of origin
33. PipMaker-a web server for aligning two genomic DNA sequences
34. Structure of the imprinted mouse Snrpn gene and establishment of its parental-specific methylation pattern
35. H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis-acting regulatory region upstream of H19
36. Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumor
37. Relaxation of IGF2 imprinting in Wilms tumours associated with specific changes in IGF2 methylation
38. Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region
39. The mouse insulin-like growth factor II/cation-independent mannose 6-phosphate (IGF-II/MPR) receptor gene: Molecular cloning and genomic organization
40. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
41. A novel L23-related gene 40 kb downstream of the imprinted H19 gene is biallelically expressed in mid-fetal and adult human tissues
42. Disruption of insulin-like growth factor 2 imprinting in Beckwith-Weidemann syndrome
43. Shotgun sequencing
44. Imprinting insulation
45. Imprinted expression of the Igf2r gene depends on an intronic CpG island
46. Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes
47. Post-processing long pairwise alignments
48. Structure and expression of the mouse L23mrp gene downstream of the imprinted H19 gene: Biallelic expression and lack of interaction with the H19 enhancers