메뉴 건너뛰기




Volumn 19, Issue 1, 1998, Pages 19-24

The impact of L1 retrotransposons on the human genome

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BETA GLOBIN; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; DNA; ENDONUCLEASE; INTEGRASE; MESSENGER RNA; PROTEIN; RNA; RNA BINDING PROTEIN; RNA POLYMERASE II; TRANSPOSASE;

EID: 17344370076     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng0598-19     Document Type: Review
Times cited : (413)

References (68)
  • 1
    • 0028920059 scopus 로고
    • Ancestral, mammalian-wide subfamilies of LINE-1 repetitive sequences
    • Smit, A.F., Toth, G., Riggs, A.D. & Jurka, J. Ancestral, mammalian-wide subfamilies of LINE-1 repetitive sequences. J. Mol. Biol. 246, 401-417 (1995).
    • (1995) J. Mol. Biol. , vol.246 , pp. 401-417
    • Smit, A.F.1    Toth, G.2    Riggs, A.D.3    Jurka, J.4
  • 2
    • 0030479536 scopus 로고    scopus 로고
    • The origin of interspersed repeats in the human genome
    • Smit, A.F. The origin of interspersed repeats in the human genome. Curr. Opin. Genet. Dev. 6, 743-748 (1996).
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 743-748
    • Smit, A.F.1
  • 3
    • 0022349108 scopus 로고
    • Reverse transcription in the eukaryotic genome: Retroviruses, pararetroviruses, retrotransposons, and retrotranscripts
    • Temin, H.M. Reverse transcription in the eukaryotic genome: retroviruses, pararetroviruses, retrotransposons, and retrotranscripts. Mol. Biol. Evol. 2, 455-468 (1985).
    • (1985) Mol. Biol. Evol. 2 , pp. 455-468
    • Temin, H.M.1
  • 6
    • 0030662074 scopus 로고    scopus 로고
    • Molecular reconstruction of sleeping beauty, a Tc1-like transposon from fish, and its transposition in human cells
    • Ivies, Z., Hackett, P.B., Plasterk, R.H. & Izsvák, Z. Molecular Reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 91, 501-510 (1997).
    • (1997) Cell , vol.91 , pp. 501-510
    • Ivies, Z.1    Hackett, P.B.2    Plasterk, R.H.3    Izsvák, Z.4
  • 7
    • 0029938821 scopus 로고    scopus 로고
    • The viruses in all of us: Characteristics and biological significance of human endogenous retrovirus sequences
    • Lower, R., Lower, J. & Kurth, R. The viruses in all of us: characteristics and biological significance of human endogenous retrovirus sequences. Proc. Natl. Acad. Sci. USA 93, 5177-5184 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5177-5184
    • Lower, R.1    Lower, J.2    Kurth, R.3
  • 8
    • 0023946286 scopus 로고
    • Human genome organization: Alu, lines, and the molecular structure of metaphase chromosome bands
    • Korenberg, J.R. & Rykowski, M.C. Human genome organization: Alu, lines, and the molecular structure of metaphase chromosome bands. Cell 53, 391-400 (1988).
    • (1988) Cell , vol.53 , pp. 391-400
    • Korenberg, J.R.1    Rykowski, M.C.2
  • 9
    • 0023635633 scopus 로고
    • LINE-1: A mammalian transposable element
    • Fanning, T.G. & Singer, M.F. LINE-1: a mammalian transposable element. Biochim. Biophys. Acta 910, 203-212 (1987).
    • (1987) Biochim. Biophys. Acta , vol.910 , pp. 203-212
    • Fanning, T.G.1    Singer, M.F.2
  • 10
    • 0023867459 scopus 로고
    • Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man
    • Kazazian, H.H., Jr. et al. Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man. Nature 332, 164-166 (1988).
    • (1988) Nature , vol.332 , pp. 164-166
    • Kazazian Jr., H.H.1
  • 11
    • 0024655257 scopus 로고
    • Characterization of a nondeleterious L1 insertion in an intron of the human factor VIII gene and further evidence of open reading frames in functional L1 elements
    • Woods-Samuels, P. et al. Characterization of a nondeleterious L1 insertion in an intron of the human factor VIII gene and further evidence of open reading frames in functional L1 elements. Genomics 4, 290-296 (1989).
    • (1989) Genomics , vol.4 , pp. 290-296
    • Woods-Samuels, P.1
  • 12
    • 0028337602 scopus 로고
    • A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion
    • Holmes, S.E., Dombrowski, B.A., Krebs, C.M., Boehm, C.D. & Kazazian, H.H., Jr. A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion. Nature Genet. 7, 143-148 (1994).
    • (1994) Nature Genet. , vol.7 , pp. 143-148
    • Holmes, S.E.1    Dombrowski, B.A.2    Krebs, C.M.3    Boehm, C.D.4    Kazazian Jr., H.H.5
  • 13
    • 0027258342 scopus 로고
    • Insertion of a 5′ truncated L1 element into the 3′ end of exon 44 of the dystrophin gene resulted in skipping of the exon during splicing in a case of Duchenne muscular dystrophy
    • Narita, N. et al. Insertion of a 5′ truncated L1 element into the 3′ end of exon 44 of the dystrophin gene resulted in skipping of the exon during splicing in a case of Duchenne muscular dystrophy. J. Clin. Invest 91, 1862-1867 (1993).
    • (1993) J. Clin. Invest , vol.91 , pp. 1862-1867
    • Narita, N.1
  • 14
    • 0026503996 scopus 로고
    • Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer
    • Miki, Y. et al. Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer. Cancer Res. 52, 643-645 (1992).
    • (1992) Cancer Res. , vol.52 , pp. 643-645
    • Miki, Y.1
  • 15
    • 0023948714 scopus 로고
    • Unit-length Line-1 transcripts in human teratocarcinoma cells
    • Skowronski, J., Fanning, T.G. & Singer, M.F. Unit-length Line-1 transcripts in human teratocarcinoma cells. Mol. Cell. Biol. 8, 1385-1397 (1988).
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 1385-1397
    • Skowronski, J.1    Fanning, T.G.2    Singer, M.F.3
  • 16
    • 0027874926 scopus 로고
    • Haemophilia B due to a de novo insertion of a human-specific Alu subfamily member within the coding region of the factor IX gene
    • Vidaud, D. et al. Haemophilia B due to a de novo insertion of a human-specific Alu subfamily member within the coding region of the factor IX gene. Eur. J. Hum. Genet. 1, 30-36 (1993).
    • (1993) Eur. J. Hum. Genet. , vol.1 , pp. 30-36
    • Vidaud, D.1
  • 17
    • 0025951042 scopus 로고
    • A de novo Alu insertion results in neurofibromatosis type 1
    • Wallace, M.R. et al. A de novo Alu insertion results in neurofibromatosis type 1. Nature 353, 864-866 (1991).
    • (1991) Nature , vol.353 , pp. 864-866
    • Wallace, M.R.1
  • 19
    • 0028175530 scopus 로고
    • Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion
    • Kingsmore, S.F. et al. Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion. Nature Genet. 7, 136-141 (1994).
    • (1994) Nature Genet. , vol.7 , pp. 136-141
    • Kingsmore, S.F.1
  • 20
    • 0027996651 scopus 로고
    • The spastic mouse: Aberrant splicing of glycine receptor beta subunit mRNA caused by intronic insertion of L1 element
    • Mulhardt, C. et al. The spastic mouse: aberrant splicing of glycine receptor beta subunit mRNA caused by intronic insertion of L1 element. Neuron 13, 1003-1015 (1994).
    • (1994) Neuron , vol.13 , pp. 1003-1015
    • Mulhardt, C.1
  • 21
    • 8944258929 scopus 로고    scopus 로고
    • Dysfunction of the Orleans reeler gene arising from exon skipping due to transposition of a full-length copy of an active L1 sequence into the skipped exon
    • Takahara, T. et al. Dysfunction of the Orleans reeler gene arising from exon skipping due to transposition of a full-length copy of an active L1 sequence into the skipped exon. Hum. Mol. Genet. 5, 989-993 (1996).
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 989-993
    • Takahara, T.1
  • 22
    • 0030015959 scopus 로고    scopus 로고
    • Mutation detection in the med and medJ alleles of the sodium channel Scn8a. Unusual splicing due to a minor class AT-AC intron
    • Kohrman, D.C., Harris, J.B. & Meisler, M.H. Mutation detection in the med and medJ alleles of the sodium channel Scn8a. Unusual splicing due to a minor class AT-AC intron. J. Biol. Chem. 271, 17576-17581 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 17576-17581
    • Kohrman, D.C.1    Harris, J.B.2    Meisler, M.H.3
  • 23
    • 0031172188 scopus 로고    scopus 로고
    • The bg allele mutation is due to a LINE1 element retrotransposition
    • Perou, C.M., Pryor, R.J., Naas, T.P. & Kaplan, J. The bg allele mutation is due to a LINE1 element retrotransposition. Genomics 42, 366-368 (1997).
    • (1997) Genomics , vol.42 , pp. 366-368
    • Perou, C.M.1    Pryor, R.J.2    Naas, T.P.3    Kaplan, J.4
  • 24
    • 0024254164 scopus 로고
    • The intracisternal A-particle gene family: Structure and functional aspects
    • Kuff, E.L. & Lueders, K.K. The intracisternal A-particle gene family: structure and functional aspects. Adv. Cancer Res. 51, 183-276 (1988).
    • (1988) Adv. Cancer Res. , vol.51 , pp. 183-276
    • Kuff, E.L.1    Lueders, K.K.2
  • 26
    • 0028245837 scopus 로고
    • Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage
    • Michaud, E.J. et al. Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage. Genes Dev. 8, 1463-1472 (1994).
    • (1994) Genes Dev. , vol.8 , pp. 1463-1472
    • Michaud, E.J.1
  • 27
    • 0030048204 scopus 로고    scopus 로고
    • Molecular basis of the pleiotropic phenotype of mice carrying the hypervariable yellow (Ahvy) mutation at the agouti locus
    • Argeson, A.C., Nelson, K.K. & Siracusa, L.D. Molecular basis of the pleiotropic phenotype of mice carrying the hypervariable yellow (Ahvy) mutation at the agouti locus. Genetics 142, 557-567 (1996).
    • (1996) Genetics , vol.142 , pp. 557-567
    • Argeson, A.C.1    Nelson, K.K.2    Siracusa, L.D.3
  • 28
    • 0030787866 scopus 로고    scopus 로고
    • The mouse pale ear (ep) mutation is the homologue of human Hermansky-Pudlak syndrome
    • Gardner, J.M. et al. The mouse pale ear (ep) mutation is the homologue of human Hermansky-Pudlak syndrome. Proc. Natl. Acad. Sci. USA 94, 9238-9243 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9238-9243
    • Gardner, J.M.1
  • 29
    • 0031006852 scopus 로고    scopus 로고
    • The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: Positional complementation cloning and extragenic suppression
    • Hamilton, B.A. et al. The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: positional complementation cloning and extragenic suppression. Neuron 18, 711-722 (1997).
    • (1997) Neuron , vol.18 , pp. 711-722
    • Hamilton, B.A.1
  • 30
    • 0031229599 scopus 로고    scopus 로고
    • IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa
    • Kuster, J.E., Guarnieri, M.H., Ault, J.G., Flaherty, L. & Swiatek, P.J. IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa. Mamm. Genome 8, 673-681 (1997).
    • (1997) Mamm. Genome , vol.8 , pp. 673-681
    • Kuster, J.E.1    Guarnieri, M.H.2    Ault, J.G.3    Flaherty, L.4    Swiatek, P.J.5
  • 31
    • 0025062325 scopus 로고
    • Cloning of the T gene required in mesoderm formation in the mouse
    • Herrmann, B.G., Labeit, S., Poustka, A., King, T.R. & Lehrach, H. Cloning of the T gene required in mesoderm formation in the mouse. Nature 343, 617-622 (1990).
    • (1990) Nature , vol.343 , pp. 617-622
    • Herrmann, B.G.1    Labeit, S.2    Poustka, A.3    King, T.R.4    Lehrach, H.5
  • 32
    • 0025932612 scopus 로고
    • Inactivation of muscle chloride channel by transposon insertion in myotonic mice
    • Steinmeyer, K. et al. Inactivation of muscle chloride channel by transposon insertion in myotonic mice. Nature 354, 304-308 (1991).
    • (1991) Nature , vol.354 , pp. 304-308
    • Steinmeyer, K.1
  • 33
    • 0027477302 scopus 로고
    • Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of Ipr mice
    • Adachi, M., Watanabe-Fukunaga, R. & Nagata, S. Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of Ipr mice. Proc. Natl. Acad. Sci. USA 90, 1756-1760 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1756-1760
    • Adachi, M.1    Watanabe-Fukunaga, R.2    Nagata, S.3
  • 34
    • 0031570346 scopus 로고    scopus 로고
    • The molecular basis of the obese mutation in ob2J mice
    • Moon, B.C. & Friedman, J.M. The molecular basis of the obese mutation in ob2J mice. Genomics 42, 152-156 (1997).
    • (1997) Genomics , vol.42 , pp. 152-156
    • Moon, B.C.1    Friedman, J.M.2
  • 35
    • 0030031158 scopus 로고    scopus 로고
    • Mutations in the founder of the MIP gene family underlie cataract development in the mouse
    • Shiels, A. & Bassnett, S. Mutations in the founder of the MIP gene family underlie cataract development in the mouse. Nature Genet. 12, 212-215 (1996).
    • (1996) Nature Genet. , vol.12 , pp. 212-215
    • Shiels, A.1    Bassnett, S.2
  • 36
    • 0030768084 scopus 로고    scopus 로고
    • Murine model of Niemann-Pick C disease: Mutation in a cholesterol homeostasis gene
    • Loftus, S.K. et al. Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene. Science 277, 232-235 (1997).
    • (1997) Science , vol.277 , pp. 232-235
    • Loftus, S.K.1
  • 38
    • 0030606320 scopus 로고    scopus 로고
    • High frequency retrotransposition in cultured mammalian cells
    • Moran, J.V. et al. High frequency retrotransposition in cultured mammalian cells. Cell 87, 917-927 (1996).
    • (1996) Cell , vol.87 , pp. 917-927
    • Moran, J.V.1
  • 39
    • 0030903621 scopus 로고    scopus 로고
    • Many human L1 elements are capable of retrotransposition
    • Sassaman, D.M. et al. Many human L1 elements are capable of retrotransposition. Nature Genet. 16, 37-43 (1997).
    • (1997) Nature Genet. , vol.16 , pp. 37-43
    • Sassaman, D.M.1
  • 40
    • 0032518909 scopus 로고    scopus 로고
    • An actively retrotransposing, novel subfamily of mouse L1 elements
    • Naas, T.P. et al. An actively retrotransposing, novel subfamily of mouse L1 elements. EMBO J. 17, 590-597 (1998).
    • (1998) EMBO J. , vol.17 , pp. 590-597
    • Naas, T.P.1
  • 42
    • 0027450385 scopus 로고
    • Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition
    • Luan, D.D., Korman, M.H., Jakubczak, J.L. & Eickbush, T.H. Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition. Cell 72, 595-605 (1993).
    • (1993) Cell , vol.72 , pp. 595-605
    • Luan, D.D.1    Korman, M.H.2    Jakubczak, J.L.3    Eickbush, T.H.4
  • 43
    • 0025223152 scopus 로고
    • Identification, characterization, and cell specificity of a human LINE-1 promoter
    • Swergold, G.D. Identification, characterization, and cell specificity of a human LINE-1 promoter. Mol. Cell. Biol. 10, 6718-6729 (1990).
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6718-6729
    • Swergold, G.D.1
  • 44
    • 0028274570 scopus 로고
    • Developmental and cell type specificity of LINE-1 expression in mouse testis: Implications for transposition
    • Branciforte, D. & Martin, S.L. Developmental and cell type specificity of LINE-1 expression in mouse testis: implications for transposition. Mol. Cell. Biol. 14, 2584-2592 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2584-2592
    • Branciforte, D.1    Martin, S.L.2
  • 45
    • 0026553846 scopus 로고
    • Active LINE-1 retrotransposons in human testicular cancer
    • Bratthauer, G.L. & Fanning, T.G. Active LINE-1 retrotransposons in human testicular cancer. Oncogene 7, 507-510 (1992).
    • (1992) Oncogene , vol.7 , pp. 507-510
    • Bratthauer, G.L.1    Fanning, T.G.2
  • 46
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • Yoder, J.A., Walsh, C.P. & Bestor, T.H. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 13, 335-340 (1997).
    • (1997) Trends Genet. , vol.13 , pp. 335-340
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3
  • 47
    • 0029134032 scopus 로고
    • RNA polymerase III dependence of the human L1 promoter and possible participation of the RNA polymerase II factor YY1 in the RNA polymerase III transcription system
    • Kurose, K., Hata, K., Hattori, M. & Sakaki, Y. RNA polymerase III dependence of the human L1 promoter and possible participation of the RNA polymerase II factor YY1 in the RNA polymerase III transcription system. Nucleic Acids Res. 23, 3704-3709 (1995).
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3704-3709
    • Kurose, K.1    Hata, K.2    Hattori, M.3    Sakaki, Y.4
  • 48
    • 0027500890 scopus 로고
    • Binding of the ubiquitous nuclear transcription factor YY1 to a cis regulatory sequence in the human LINE-1 transposable element
    • Becker, K.G., Swergold, G.D., Ozato, K. & Thayer, R.E. Binding of the ubiquitous nuclear transcription factor YY1 to a cis regulatory sequence in the human LINE-1 transposable element. Hum. Mol. Genet. 2, 1697-1702 (1993).
    • (1993) Hum. Mol. Genet. , vol.2 , pp. 1697-1702
    • Becker, K.G.1    Swergold, G.D.2    Ozato, K.3    Thayer, R.E.4
  • 49
    • 0025026986 scopus 로고
    • Translation of LINE-1 DNA elements in vitro and in human cells
    • Leibold, D.M. et al. Translation of LINE-1 DNA elements in vitro and in human cells. Proc. Natl. Acad. Sci. USA 87, 6990-6994 (1990).
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6990-6994
    • Leibold, D.M.1
  • 50
    • 0030042251 scopus 로고    scopus 로고
    • Cytoplasmic ribonucleoprotein complexes containing human LINE-1 protein and RNA
    • Hohjoh, H. & Singer, M.F. Cytoplasmic ribonucleoprotein complexes containing human LINE-1 protein and RNA. EMBO J. 15, 630-639 (1996).
    • (1996) EMBO J. , vol.15 , pp. 630-639
    • Hohjoh, H.1    Singer, M.F.2
  • 51
    • 0030870342 scopus 로고    scopus 로고
    • Sequence-specific single-strand RNA binding protein encoded by the human LINE-1 retrotransposon
    • Hohjoh, H. & Singer, M.F. Sequence-specific single-strand RNA binding protein encoded by the human LINE-1 retrotransposon. EMBO J. 16, 6034-6043 (1997).
    • (1997) EMBO J. , vol.16 , pp. 6034-6043
    • Hohjoh, H.1    Singer, M.F.2
  • 52
    • 0025740894 scopus 로고
    • Ribonucleoprotein particles with LINE-1 RNA in mouse embryonal carcinoma cells
    • Martin, S.L. Ribonucleoprotein particles with LINE-1 RNA in mouse embryonal carcinoma cells. Mol. Cell. Biol. 11, 4804-4807 (1991).
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4804-4807
    • Martin, S.L.1
  • 53
    • 0028893337 scopus 로고
    • Characterization of a LINE-1 cDNA that originated from RNA present in ribonucleoprotein particles: Implications for the structure of an active mouse LINE-1
    • Martin, S.L. Characterization of a LINE-1 cDNA that originated from RNA present in ribonucleoprotein particles: implications for the structure of an active mouse LINE-1. Gene 153, 261-266 (1995).
    • (1995) Gene , vol.153 , pp. 261-266
    • Martin, S.L.1
  • 54
    • 0027144076 scopus 로고
    • Translation of the human LINE-1 element, L1Hs
    • McMillan, J.P. & Singer, M.F. Translation of the human LINE-1 element, L1Hs. Proc. Natl. Acad. Sci. USA 90, 11533-11537 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11533-11537
    • McMillan, J.P.1    Singer, M.F.2
  • 55
    • 0009969062 scopus 로고    scopus 로고
    • Human L1 retrotransposon encodes a conserved endonuclease required fo retrotransposition
    • Feng, Q., Moran, J.V., Kazazian, H.H. & Boeke, J.D. Human L1 retrotransposon encodes a conserved endonuclease required fo retrotransposition. Cell 87, 905-916 (1996).
    • (1996) Cell , vol.87 , pp. 905-916
    • Feng, Q.1    Moran, J.V.2    Kazazian, H.H.3    Boeke, J.D.4
  • 56
    • 0028923440 scopus 로고
    • Structure and function of the multifunctional DNA-repair enzyme exonuclease III
    • Mol, CD., Kuo, C.F., Thayer, M.M., Cunningham, R.P. & Tainer, J.A. Structure and function of the multifunctional DNA-repair enzyme exonuclease III. Nature 374, 381-386 (1995).
    • (1995) Nature , vol.374 , pp. 381-386
    • Mol, C.D.1    Kuo, C.F.2    Thayer, M.M.3    Cunningham, R.P.4    Tainer, J.A.5
  • 57
    • 0030728449 scopus 로고    scopus 로고
    • The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites
    • Gorman, M.A. et al. The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. EMBO J. 16, 6548-6558 (1997).
    • (1997) EMBO J. , vol.16 , pp. 6548-6558
    • Gorman, M.A.1
  • 58
    • 0025006614 scopus 로고
    • Origin and evolution of retroelements based upon their reverse transcriptase sequences
    • Xiong, Y. & Eickbush, T.H. Origin and evolution of retroelements based upon their reverse transcriptase sequences. EMBO J. 9, 3353-3362 (1990).
    • (1990) EMBO J. , vol.9 , pp. 3353-3362
    • Xiong, Y.1    Eickbush, T.H.2
  • 59
    • 0030819894 scopus 로고    scopus 로고
    • Telomerase catalytic subunit homologs from fission yeast and human
    • Nakamura, T.M. et al. Telomerase catalytic subunit homologs from fission yeast and human. Science 277, 955-959 (1997).
    • (1997) Science , vol.277 , pp. 955-959
    • Nakamura, T.M.1
  • 60
    • 0030848018 scopus 로고    scopus 로고
    • Telomerase and retrotransposons: Which came first?
    • Eickbush, T.H. Telomerase and retrotransposons: which came first? Science 277, 911-912 (1997).
    • (1997) Science , vol.277 , pp. 911-912
    • Eickbush, T.H.1
  • 61
    • 0030813818 scopus 로고    scopus 로고
    • Functional difference between the human LINE retrotransposon and retroviral reverse transcriptases for in vivo mRNA reverse transcriptase
    • Dhellin, O., Maestre, J. & Heidmann, T. Functional difference between the human LINE retrotransposon and retroviral reverse transcriptases for in vivo mRNA reverse transcriptase. EMBO J. 16, 6590-6602 (1997).
    • (1997) EMBO J. , vol.16 , pp. 6590-6602
    • Dhellin, O.1    Maestre, J.2    Heidmann, T.3
  • 62
    • 0031135862 scopus 로고    scopus 로고
    • LINEs and Alus - The polyA connection
    • Boeke, J.D. LINEs and Alus - the polyA connection. Nature Genet. 16, 6-7 (1997).
    • (1997) Nature Genet. , vol.16 , pp. 6-7
    • Boeke, J.D.1
  • 63
    • 0027483055 scopus 로고
    • A cellular protein binds B1 and Alu small cytoplasmic RNAs in vitro
    • Chang, D.Y. & Maraia, R.J. A cellular protein binds B1 and Alu small cytoplasmic RNAs in vitro. J. Biol. Chem. 268, 6423-6428 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 6423-6428
    • Chang, D.Y.1    Maraia, R.J.2
  • 64
    • 0028302027 scopus 로고
    • A human Alu RNA-binding protein whose expression is associated with accumulation of small cytoplasmic Alu RNA
    • Chang, D.Y. et al. A human Alu RNA-binding protein whose expression is associated with accumulation of small cytoplasmic Alu RNA. Mol. Cell. Biol. 14, 3949-3959 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3949-3959
    • Chang, D.Y.1
  • 65
    • 0028901106 scopus 로고
    • A trinucleotide repeat-associated increase in the level of Alu RNA-binding protein occurred during the same period as the major Alu amplification that accompanied anthropoid evolution
    • Chang, D.Y., Sasaki-Tozawa, N., Green, L.K. & Maraia, R.J. A trinucleotide repeat-associated increase in the level of Alu RNA-binding protein occurred during the same period as the major Alu amplification that accompanied anthropoid evolution. Mol. Cell. Biol. 15, 2109-2116 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2109-2116
    • Chang, D.Y.1    Sasaki-Tozawa, N.2    Green, L.K.3    Maraia, R.J.4
  • 66
    • 0031055331 scopus 로고    scopus 로고
    • Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons
    • Jurka, J. Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons. Proc. Natl. Acad. Sci. U.S.A. 94, 1872-1877 (1997).
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 1872-1877
    • Jurka, J.1
  • 67
    • 0031571661 scopus 로고    scopus 로고
    • cDNAs derived from primary and small cytoplasmic Alu (scAlu) transcripts
    • Shaikh, T.H., Roy, A.M., Kim, J., Batzer, M.A. & Deininger, P.L. cDNAs derived from primary and small cytoplasmic Alu (scAlu) transcripts. J. Mol. Biol. 271, 222-234 (1997).
    • (1997) J. Mol. Biol. , vol.271 , pp. 222-234
    • Shaikh, T.H.1    Roy, A.M.2    Kim, J.3    Batzer, M.A.4    Deininger, P.L.5
  • 68
    • 0029058441 scopus 로고
    • RNA template requirements for target DNA-primed reverse transcription by the R2 retrotransposable element
    • Luan, D.D. & Eickbush, T.H. RNA template requirements for target DNA-primed reverse transcription by the R2 retrotransposable element. Mol. Cell. Biol. 15, 3882-3891 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3882-3891
    • Luan, D.D.1    Eickbush, T.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.